Amycolatopsis mongoliensis: QRX60_00125
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Entry
QRX60_00125 CDS
T09938
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
amog
Amycolatopsis mongoliensis
Pathway
amog00010
Glycolysis / Gluconeogenesis
amog00020
Citrate cycle (TCA cycle)
amog00620
Pyruvate metabolism
amog00785
Lipoic acid metabolism
amog01100
Metabolic pathways
amog01110
Biosynthesis of secondary metabolites
amog01120
Microbial metabolism in diverse environments
amog01200
Carbon metabolism
amog01210
2-Oxocarboxylic acid metabolism
Module
amog_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amog00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
QRX60_00125 (aceE)
00020 Citrate cycle (TCA cycle)
QRX60_00125 (aceE)
00620 Pyruvate metabolism
QRX60_00125 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
QRX60_00125 (aceE)
Enzymes [BR:
amog01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
QRX60_00125 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
WIY02319
UniProt:
A0A9Y2JRN7
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All DBs
Position
30104..32899
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AA seq
931 aa
AA seq
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MAPQNDGASGKETPARVRVIRDGLAAHLPDIDPEETAEWLDSFDEALARGGQQRARYLML
RILERARERNVGVPALTSTDYVNTIPTENEPWFPGDEEIERRYRAYIRWNAAIMVHRAQR
PGVGVGGHISTYASSAALYEVGFNHFFRGKDHSGGGDQIYIQGHASPGIYARAFLEGRLT
EQQLDGFRQEYSHAGEGGGLPSYPHPRLMPEFWENPTVSMGLGPMNAIYQARFNRYLRDR
GIKNTDDQHVWAFLGDGEMDEAESRGLIHVAAGEGLDNLTFVINCNLQRLDGPVRGNGKI
IQELESYFRGAGWNVIKVIWGREWDSLLHADRDGALVNLMNVTPDGDYQTYKANDGAFVR
EHFFGRDPRTKDLVKDLSDADIWNLKRGGHDYRKVYAAYKSALEHHGQPTVILAHTIKGY
GLGPAFEGRNATHQMKKLTLDDLKLFRDSQRIPISDEELERDPKLPPYYHPGANSPEIEY
LIGRRKALGGFLPERRPKAAKALVLPGDKVYEGIRKGSGKQEVATTMAFVRLVRELAKDS
EIGKRVVPIIPDEARTFGLDSMFPTAKIYNPHGQTYTSVDASLMLAYKESEKGQLLHEGI
NEAGSTASFTAVGTSYATHGEPMIPIYIFYSMFGFQRTGDGLYAAADQMARGFVLGATAG
RTTLTGEGLQHADGHSLLLAATNPAAVAYDPAWSFEIAHIVKDGLRRMYGEAGPDGNGEN
VFYYMTIYNEPYQQPAEPENLDVDGLLKGLYKYAGAPEGDGPEVQILVSGVTMPDALKAQ
KMLAEEWGVRASVWSATSWTELRREAVEIDHDNLLYPGSEPRVPYVTEALSRANGPVVAV
SDWMRAVPDLIRPYVPTDMLTLGTDGFGFSDTRPAARRKFLVDAESITVGALSILAKRGE
VDQAKVLEAATKYRLDDIAAAGPQTSDSGSA
NT seq
2796 nt
NT seq
+upstream
nt +downstream
nt
ttggccccgcagaacgacggcgcctccggcaaggagaccccggcacgcgtacgcgtcatc
cgtgacggattggcggcgcacctgcccgacatcgacccggaggagaccgccgagtggctg
gactccttcgacgaggcgctggccaggggaggtcagcagcgggcccggtacctgatgctg
cgcatcctggagcgcgcccgggaacgcaacgtcggcgtacccgcgctgacctcgacggac
tacgtcaacaccatccccaccgagaacgaaccgtggttccccggtgacgaggagatcgag
cgccggtaccgggcctacatccggtggaacgccgcgatcatggtgcatcgggcgcagcgc
cccggcgtcggcgtcggcgggcacatctcgacctacgcctcctccgccgcgctctacgaa
gtcgggttcaaccacttcttccgcggcaaggaccactccggcggcggcgaccagatctac
atccagggccacgcctcccccggcatctacgcccgcgcgttcctcgagggccggctgacc
gagcagcagctcgacggcttccgccaggagtactcgcacgccggcgagggcggcggcctg
ccgtcgtacccgcacccgcggctgatgccggagttctgggagaacccgacggtgtcgatg
ggcctcggcccgatgaacgccatctaccaggcgcggttcaaccgctacctgcgcgaccgc
ggcatcaagaacaccgacgaccagcacgtctgggcgttcctcggcgacggcgagatggac
gaggccgagtcgcgcggcctgatccacgtcgcggccggcgagggcctcgacaacctgacc
ttcgtgatcaactgcaacctgcagcggctcgacggcccggtgcgcggcaacggcaagatc
atccaggagctggagtcgtacttccgcggcgccggctggaacgtcatcaaggtcatctgg
ggccgcgagtgggactcgctgctgcacgccgaccgcgacggcgcgctggtcaacctgatg
aacgtgacgcccgacggcgactaccagacgtacaaggccaacgacggcgccttcgtccgc
gagcacttcttcggccgcgacccgcggacgaaggacctggtcaaggacctctccgacgcc
gacatctggaacctcaagcgcggcggccacgactaccgcaaggtctacgcggcgtacaag
tcggcgctggagcaccacggccagccgacggtgatcctggcccacaccatcaagggctac
ggcctgggcccggcgttcgagggccgcaacgccacgcaccagatgaagaagctcaccctc
gacgacctgaagctgttccgcgactcgcagcggatcccgatcagcgacgaggagctcgag
cgcgacccgaagctgccgccgtactaccacccgggcgcgaactcgcccgagatcgagtac
ctgatcggccgccgcaaggcgctcggcggcttcctgccggaacgccgcccgaaggccgcc
aaggcgctcgtgctgcccggcgacaaggtctacgagggcatccggaagggctccggcaag
caggaggtcgccaccacgatggcgttcgtccggctggtccgcgagctggcgaaggactcc
gagatcggcaagcgcgtcgtcccgatcatcccggacgaggcccgcaccttcggcctcgac
tcgatgttccctacggccaagatctacaacccgcacggccagacgtacacctcggtcgac
gcgagcctgatgctggcctacaaggagtccgagaagggccagctgctgcacgagggcatc
aacgaggcgggctcgaccgcgtcgttcaccgccgtcggcacgtcgtacgcgacgcacggc
gagccgatgatcccgatctacatcttctactcgatgttcgggttccagcggaccggtgac
ggcctgtacgccgccgccgaccagatggcccgcgggttcgtcctcggcgccaccgccggc
cgcaccacgctgaccggcgagggcctgcagcacgccgacgggcactcgctgctgctggcg
gcgaccaacccggccgcggtcgcctacgacccggcgtggtcgttcgagatcgcgcacatc
gtgaaggacggcctgcgccggatgtacggcgaggccggcccggacggcaacggcgagaac
gtcttctactacatgacgatctacaacgagccgtaccagcagcccgccgagccggagaac
ctcgacgtcgacggcctgctgaagggtctgtacaagtacgctggcgcgcccgagggcgac
ggcccggaggtgcagatcctcgtctcgggcgtcacgatgccggacgcgctcaaggcccag
aagatgctggccgaagagtggggtgtgcgggcgtcggtgtggtcggccacgtcgtggacc
gagctgcggcgcgaggccgtcgagatcgaccacgacaacctgctctacccgggcagcgag
ccgcgcgtgccgtacgtcaccgaggcgctttcacgcgcgaacggcccggtcgtggcggtg
tcggactggatgcgcgcggtgccggacctgatccgcccgtacgtgccgaccgacatgctg
acgctgggcaccgacgggttcgggttctccgacacccggccggcggcgcggcggaagttc
ctggtcgacgccgagtcgatcaccgtcggcgcgctgtcgatcctggccaagcgcggcgag
gtcgaccaggcgaaggtcctcgaagcggccacgaagtaccggctcgacgacatcgcggcc
gccgggccgcagacgtcggattccggcagcgcgtga
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