KEGG   Amycolatopsis methanolica: AMETH_1485
Entry
AMETH_1485        CDS       T03230                                 
Symbol
ligA
Name
(GenBank) DNA ligase
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
amq  Amycolatopsis methanolica
Pathway
amq03030  DNA replication
amq03410  Base excision repair
amq03420  Nucleotide excision repair
amq03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:amq00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    AMETH_1485 (ligA)
   03410 Base excision repair
    AMETH_1485 (ligA)
   03420 Nucleotide excision repair
    AMETH_1485 (ligA)
   03430 Mismatch repair
    AMETH_1485 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:amq03032]
    AMETH_1485 (ligA)
   03400 DNA repair and recombination proteins [BR:amq03400]
    AMETH_1485 (ligA)
Enzymes [BR:amq01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     AMETH_1485 (ligA)
DNA replication proteins [BR:amq03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     AMETH_1485 (ligA)
DNA repair and recombination proteins [BR:amq03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     AMETH_1485 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     AMETH_1485 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     AMETH_1485 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      AMETH_1485 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 Nlig-Ia PTCB-BRCT HHH Zn_ribbon_Nudix
Other DBs
NCBI-ProteinID: AIJ21577
UniProt: A0A076MUQ2
LinkDB
Position
1511374..1513494
AA seq 706 aa
MSETPAAQDVTEVPAEVRERHGALAEEVRGHQFRYYVLDSPVISDGEFDALLKELERLES
EYPGLATPDSPTQNVGGTFSTDFVAVDHLERMMSLDNVFDEEELRAWVDRVEREVGGSTQ
YLCELKIDGLAINLLYEKGRLVRGLTRGDGRTGEDVTLNVRTLEQVPETLTGTDEYPVPD
LVEVRGEVFFRVEDFAELNARLVEAGKPPFANPRNTAAGSLRQKDPKVTRSRKLRLICHG
LGKREGFEPARQSEAYEALAAWGLPVSSHTKVVDKASELLDHIRYWGEHRHDAEHEIDGI
VVKVDQVSLQRRLGSTSRAPRWAIAYKYPPEEATTRLLDIQVNVGRTGRVTPFAVMEPVK
VAGSTVAMATLHNAQEVKRKGVLIGDRVVIRKAGDVIPEVLGPVVDVRTGDEREFIMPTF
CPECGTKLAHQKEGDVDIRCPNARSCPAQLRERLFHLAGRGAFDIEMLGYEAATALLESG
VVVDEGDIFDLDEEKLGRVELFRTKAGELSANGRKLLANLDSAKDRPLWRVLVALSIRHV
GPTAAQALAREFGSLEAIENADEAAMADVDGVGPTIAGALREWFAVDWHREVVEKWRRAG
VRMAEERDESVPRTLEGLSIVVTGSLNTFSRDEAKEAIMSRGGKAAGSVSKKTAFVVVGD
APGSKYDKAVQLKVPILDEGGFQVLLDRGPEAAAEVALPTEEPAGE
NT seq 2121 nt   +upstreamnt  +downstreamnt
gtgagtgagactccagccgcacaggacgtcaccgaggtccccgccgaggtccgcgagcgc
cacggcgcgctcgcggaagaggtgcgcgggcaccagttccggtactacgtgctggactcg
ccggtcatcagtgacggcgagttcgacgcgctgctcaaggagctggagcggctggagtcg
gagtacccgggcctggcgacgccggattcgccgacccagaacgtcggcggcactttctcc
accgacttcgtcgcggtcgaccacctcgagcgcatgatgagcctggacaacgtcttcgac
gaggaggagttgcgggcctgggtggaccgggtggagcgcgaggtcggcgggtccacgcag
tacctgtgcgagctcaagatcgacgggctggccatcaacctgctgtacgagaaggggcgg
ctggtccgcgggctcacccgcggcgacgggcggacgggtgaggacgtcacgctcaacgtc
cgcaccctcgagcaggtgccggagacgctgaccggcacggacgagtacccggtgcccgac
ctggtcgaggtgcgcggcgaggtgttcttccgggtcgaggacttcgcggagctcaacgcc
cggctggtcgaggcgggcaagccgccgttcgcgaacccgcgcaacaccgcggccgggtcg
ttgcggcagaaggacccgaaggtcacgcgcagccggaagctgcggctgatctgccacggc
ctcggcaagcgcgagggtttcgagccggcgcggcagtcggaggcctacgaggcgctggcg
gcgtgggggctgccggtgtccagccacacgaaggtcgtcgacaaggcgtccgagctgctg
gaccacatccggtactggggcgagcaccggcacgacgccgagcacgagatcgacggcatc
gtggtgaaggtcgaccaggtgtcgctgcagcggcggctgggcagcacgtcccgcgcgccg
cggtgggccatcgcctacaagtacccgccggaggaggcgaccacccggctgctcgacatc
caggtcaacgtcggccgcaccgggcgggtcacgccgttcgcggtgatggagccggtgaag
gtggccgggtcgacggtggcgatggcgacgctgcacaacgcgcaggaggtcaagcgcaag
ggcgtgctgatcggcgaccgcgtggtgatccgcaaggcgggcgacgtgatccccgaggtg
ctcggcccggtggtcgacgtgcgcaccggggacgagcgcgagttcatcatgcccacgttc
tgcccggagtgcggcacgaagctggcgcaccagaaggagggcgacgtcgacatccggtgc
cccaacgcccggtcgtgtcccgcgcagctgcgggagcggctgttccacctggccgggcgc
ggcgcgttcgacatcgagatgctgggctacgaggcggcgacggcgctgctggagtccggt
gtggtcgtcgacgagggcgacatcttcgacctggacgaggagaagctgggccgggtcgag
ctgttccgcaccaaggcgggggagctgtcggcgaacgggcgcaagctgctggccaacctg
gacagcgcgaaggaccgtccactgtggcgggtgctggtggcgttgtcgatccggcacgtc
ggccccaccgctgcccaggcgctggcgcgcgagttcggctcgctggaggcgatcgagaac
gccgacgaggccgcgatggccgatgtggacggtgtcgggccgacgatcgccggggcgttg
cgggagtggttcgccgtcgactggcaccgcgaggtggtggagaagtggcgccgagcgggg
gtccggatggcggaggagcgcgacgagtcggtgccgcgcacgctggagggcctgtccatc
gtggtgaccggttcgctgaacaccttctcgcgcgacgaggccaaggaggcgatcatgtcg
cgcggtggcaaggccgcgggctcggtgtcgaagaagacggcgttcgtcgtggtcggcgac
gcgcccgggtccaagtacgacaaggcggtgcagctgaaggtcccgatcctcgacgagggc
gggttccaggtgctgctggaccgcggcccggaggcagccgccgaggtggcgttgccgacg
gaggagccggccggtgagtga

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