KEGG   Amycolatopsis methanolica: AMETH_3562
Entry
AMETH_3562        CDS       T03230                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
amq  Amycolatopsis methanolica
Pathway
amq00270  Cysteine and methionine metabolism
amq00450  Selenocompound metabolism
amq00670  One carbon pool by folate
amq01100  Metabolic pathways
amq01110  Biosynthesis of secondary metabolites
amq01230  Biosynthesis of amino acids
amq04980  Cobalamin transport and metabolism
amq04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:amq00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    AMETH_3562 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    AMETH_3562 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    AMETH_3562 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    AMETH_3562 (metH)
   04980 Cobalamin transport and metabolism
    AMETH_3562 (metH)
Enzymes [BR:amq01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     AMETH_3562 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding CdhD
Other DBs
NCBI-ProteinID: AIJ23654
UniProt: A0A076MSP4
LinkDB
Position
complement(3675931..3679473)
AA seq 1180 aa
MSGRFSSPLLDALAARVVVADGAMGTALQAHELSLDDFAGLEGCNEILNVTRPDVVRGIH
RTYLEAGADAVETNTFGANLANLGEYGIADRIAELAEAGARLARETADEHATPDRPRFVL
GSVGPGTKLPTLGHAPYARLRDAYVEQVTGLLHGGVDAVLVETSQDLLQTKAAILGARRA
MRAVGREVPVIASITVETTGTMLLGTEVAAALAALEPLGIDVIGLNCATGPAEMSEHLRT
LSKSARVPLSVMPNAGLPELGPDGAVYPLSPEGLAEALSGFVREFGVGLVGGCCGTTGEH
IRQLAEAVRDADRAPRRPRHEPGVSSLYQAVPFEQDASVLMVGERTNANGSKKFREAMLE
GRYEDCVEIAREQTRDGAHLLDLCVDYVGRDGAADMAELAGRLATASTLPIMLDSTEPAV
LQAGLERLGGRCVVNSVNYEDGDGPGSRFQKIMRLVSEHGAAVVVMCIDEEGQARTAEWK
VRVATRTIEDLVTNWGMRVSDIIVDCLTFPITTGQEETRRDALETIEAIRELKRRYPEVQ
TTLGISNVSFGLNAAARQVLNSVFLHECVEAGLTTAIVHASKILPMARIPDEQREVALDL
VYDRRREGYDPLQKLMSLFEGVSAASRRASRAEELAALPLFERLERRIVDGERTGLEADL
DAALAEKPALDIVNDILLSGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMDKTD
SSGKGKIVLATVKGDVHDIGKNLVDIILSNNGYDVINLGIKQPVNAILDAADDHGADAIG
MSGLLVKSTVIMKENLEEMNSRGVAQRWPVLLGGAALTRTYVENDLAELYQGDVRYARDA
FEGLRLMDTIMAAKHGRAPEISAEEAAKRAERKARRERSLRIAEARKSAREPEAPIPARS
DVATDVPVPVPPFWGTRVVKGIPVAEYAALVDERATFLGQWGLRGARGGQGPSYEQLVET
EGRPRLRYWLDRLATDGVLQHAAVVYGYFPAVAEGNDLVVLTEAHADAPERTRFTFPRQT
RDRYLCLADFFRPRATGEVDVLPLTLVTMGQPIADYANELFANDAYRDYLEVHGLGVQLT
EALAEYWHRRVRQELHFTSGRAVADEDPRSVEDFFKLGYRGARFSLGYGACPNLEDRATI
VELLDAERIGVKLSEEFQLHPEQSTDAIVAHHPEAKYFNT
NT seq 3543 nt   +upstreamnt  +downstreamnt
atgtccggtcgattctcgtcaccgctgctggacgccctcgccgcgcgtgtggtcgtggcg
gacggggcgatgggcacggcgctgcaggcgcacgagctgtccctggacgacttcgcgggc
ctggaaggctgcaacgagatcctgaacgtgacccgcccggacgtggtgcggggcatccac
cgcacctacctggaggccggcgcggacgcggtcgagacgaacaccttcggcgcgaacctg
gcgaacctgggggagtacgggatcgccgaccgcatcgccgagctggccgaggcgggcgcg
cggctggcacgggagaccgccgacgagcacgcgacgccggaccgcccgcggttcgtgctg
ggctcggtcggccccggcacgaagctgcccacgctcggccacgcgccgtacgcgcggctg
cgggacgcctacgtcgagcaggtcaccggcctgctgcacggcggggtggacgcggtgctg
gtggagacgtcgcaggacctgctgcagaccaaggcggcgatcctgggtgcgcgccgggcg
atgcgcgccgtcggccgcgaggtgccggtgatcgcttcgatcacggtcgagacgaccggg
acgatgctgctgggcaccgaggtcgccgccgcgctggccgcgctggagccgctgggcatc
gacgtgatcgggctgaactgcgcgaccggcccggcggagatgagcgagcacctgcggacg
ctgtcgaagtcggcgcgggtcccgctgtcggtgatgcccaacgccggcctgcccgagctg
ggcccggacggcgcggtgtacccgctgtcgccggaaggactggccgaggcgctgtccggt
ttcgtgcgcgagttcggcgtcggcctggtcggcggctgctgcggcaccaccggcgagcac
atccggcagctggccgaggcggtgcgggacgccgaccgcgcgccccgccggccgcggcac
gagcccggcgtgtcctcgctgtaccaggcggtgccgttcgagcaggacgcctcggtgctg
atggtgggggagcgcaccaacgccaacggctccaagaagttccgcgaggccatgctcgaa
ggccgctacgaggactgcgtggagatcgcccgcgagcagacccgcgacggcgcgcacctg
ctggacctgtgcgtggactacgtcggccgggacggcgcggcggacatggccgagctggcc
gggcggctggcgacggcgtccacgctgccgatcatgctcgactccaccgagcccgcggtg
ctccaggccggcctggaacggctgggcggccggtgcgtggtcaacagcgtcaactacgag
gacggcgacggcccgggctcgcgcttccagaagatcatgcggctggtgtccgagcacggc
gccgcggtcgtggtgatgtgcatcgacgaggagggccaggcccgcacagccgagtggaag
gtccgcgtcgccacccgcacgatcgaggacctggtcaccaactggggcatgcgcgtctcc
gacatcatcgtcgactgcctgaccttcccgatcaccaccgggcaggaggagacccgccgc
gacgcgctggagacgatcgaggcgatccgcgagctcaagcgccgctacccggaggtgcag
acgacgctgggcatctccaacgtctccttcgggctcaacgccgccgcgcgccaggtgctc
aactcggtgttcctgcacgagtgcgtcgaagccgggctgaccacggcgatcgtgcacgcg
tcgaagatcctgccgatggcgcggatcccggacgagcagcgggaggtcgcgctcgacctg
gtctacgaccgccgccgggagggctacgacccgctgcagaagctgatgtcgctgttcgag
ggcgtctcggccgcgtcgcgccgggcttcgcgcgccgaggagctggccgcgctgccgctg
ttcgagcggctggagcggcggatcgtcgacggcgagcgcaccgggctggaggccgacctc
gacgccgcgctggcggagaaaccggcgctggacatcgtcaacgacatcctgctgtccggc
atgaagaccgtgggcgagctgttcgggtccggccagatgcagctgccgttcgtgctgcag
tcggccgaggtcatgaagaccgcggtggcctacctcgaaccgcacatggataagacggac
tcgtcgggcaaggggaagatcgtcctggccacggtcaagggcgacgtgcacgacatcggc
aagaacctggtcgacatcatcctgtcgaacaacggttacgacgtgatcaacttgggtatc
aagcagcccgtcaacgcgatcctggacgcggccgacgatcacggcgcggacgcgatcggc
atgtccgggctgctggtgaagtccacggtgatcatgaaggagaacctggaggagatgaac
tcccgcggcgtcgcccagcgctggcccgtcctgctcggcggcgcggcattgacccgcacc
tacgtcgagaacgacctcgccgagctctaccagggcgacgtccgctacgcgcgggacgcg
ttcgagggcctgcggctgatggacacgatcatggcggccaagcacggccgggcgccggag
atcagcgcggaggaggcggccaagagagcggagcgcaaggcccgccgcgagcggtccctg
cgcatcgccgaagcccgcaagtccgcccgagagccggaggcccccattcccgcccgttcc
gatgtcgcgaccgacgtgcccgtgcccgtgccgccgttctggggcacccgggtggtgaag
ggcatcccggtcgccgagtacgccgcactggtcgacgagcgcgcgactttcctcgggcag
tggggcctgcgcggcgcccgcggcgggcaggggcccagctacgagcagctggtggagacc
gaagggcgcccgcggctgcggtactggctggaccggctggccaccgacggggtcctgcag
cacgccgcggtggtgtacggctacttcccggccgtggccgagggcaacgacctggtggtg
ctgaccgaggcgcacgccgacgcgccggagcggacccggttcacgttcccgcggcagacc
cgcgaccgctacctgtgcctggccgacttcttccggcctcgcgccaccggcgaggtcgac
gtgctgccgctgaccctggtcactatggggcagccgatcgccgactatgccaacgagctg
ttcgcgaacgacgcctaccgcgactacctggaggtccacggcctcggcgtgcagctcacc
gaggcgctggccgagtactggcaccgccgcgtgcggcaggagctgcacttcaccagcggc
cgcgcggtcgccgacgaggacccgcgctcggtcgaggacttcttcaaactgggctaccgc
ggcgcccgcttctccctcggctacggcgcctgcccgaacctggaggaccgcgcgaccatc
gtggagctgctcgacgcggaacggatcggggtgaagctgtccgaggagttccagctgcac
cccgagcagtccaccgacgcgatcgtggcccaccaccccgaggccaagtacttcaacacc
tga

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