Amycolatopsis methanolica: AMETH_5760
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Entry
AMETH_5760 CDS
T03230
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
amq
Amycolatopsis methanolica
Pathway
amq00020
Citrate cycle (TCA cycle)
amq00630
Glyoxylate and dicarboxylate metabolism
amq00785
Lipoic acid metabolism
amq01100
Metabolic pathways
amq01110
Biosynthesis of secondary metabolites
amq01120
Microbial metabolism in diverse environments
amq01200
Carbon metabolism
amq01210
2-Oxocarboxylic acid metabolism
Module
amq_M00009
Citrate cycle (TCA cycle, Krebs cycle)
amq_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
amq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
AMETH_5760 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
AMETH_5760 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AMETH_5760 (kgd)
Enzymes [BR:
amq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
AMETH_5760 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
AMETH_5760 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
AMETH_5760 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
AMETH_5760 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AIJ25852
UniProt:
A0A076N777
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All DBs
Position
5936664..5940359
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AA seq
1231 aa
AA seq
DB search
MSSSSPASQFGPNEWLVEEMYDQFLADPSSVDAAWHEFFSDFKPTQTTESKPDAAPAPVR
EQPAKPGNGQVNQAATAPAAPAQPKPAAKPAAQPAKPAAAKPAAAKPAAAATKPAAEPES
KQLRGAAAAIAKNMDASLAVPTATSVRAVPAKLMADNRIVINNHLKRTRGGKISFTHLIG
YAMVRALQDFPNMNRHYALVDGKPHAVTPEHVNLGLAIDMKGKDGGRALVVASIKNCENM
TFRQFWQAYEDIVKKARNNKLTADDFAGTTISLTNPGGIGTNHSVPRLQAGQGAIIGVGA
MQYPAHFEGTSEETLVKLGISKIMTLTSTYDHRIIQGAESGEYLKRIHELLLGEDGFYDD
IFTSLRLPYEPVRWVSDIPEGEIDKTARVLELIDAYRMRGHLMADTDPLNYRQRRHEDLD
VLSHGLTLWDLDREFAVGGFAGQQKMKLRDVLGVLRDSYCRTVGVEYTHILDPEERRWIQ
DRVEVPHAKPDPNVQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGGETVIPMLDTVLDK
AAEHELDEVVIGMPHRGRLNVLANIVGKPISQIFQEFEGNLDPGQAHGSGDVKYHLGAEG
KYFRMFGDGETRVSLTANPSHLETVDPVLEGIVRAKQDILDKGDSDTGGFSVLPVLLHGD
AAFAGQGVVAETLNLALLRGYRTGGTVHIIINNQVGFTTAPEHSRSSQYATDVAKMIGAP
IFHVNGDDPEAAHWVAKLAVDYRQAFNKDVVIDMICYRRRGHNEGDDPSMTQPAMYDIID
TKRSVRKTYTESLIGRGDISVEEAEAALRDFSSQLEHVFNEVRELEKHPIAPSPSVEEEQ
QVPAKVPTAVPAEVIERIGDAFVNVPEGFTPHPRVKPVMERRYKMSREGGVDWAFGELLA
FGSLAMEGRLVRLSGQDSRRGTFTQRHSVLIDRKTGREYAPLQNLAEDQGRVMIYDSALS
EYAAVGFEYGYSVANSDALVLWEAQFGDFVNGAQTVIDEYISSGEAKWGQRSDVVLLLPH
GHEGQGPDHTSGRIERFLSLCAEGSMTVAVPSTPANYFHLLRRHALDGIQRPLIVFTPKS
MLRNKAATSGLEDFTGDSKFMSVIDDAEVEPGKVRKVLLTSGKLYWELVAERAKRDADDV
AIVRIEQYYPLPKKKLLAALERYTGAEVVWVQEEPENQGAWPFFGLHLPRMFPDVLGKLD
VVSRRPMAAPSAGSSKVHEVEQKALIAKAFS
NT seq
3696 nt
NT seq
+upstream
nt +downstream
nt
gtgtccagcagcagccctgcgtcacagttcggccccaacgaatggctcgtcgaggagatg
tacgaccagttcctcgccgacccctcttcagtagacgccgcatggcacgagttcttctcg
gacttcaagccgacgcagaccacggagtcgaagccggacgccgcacccgcgcccgtccgt
gagcagcccgccaagccgggcaacggccaggtcaaccaggctgcgacggccccggccgcg
cccgcccagccgaagcccgccgccaagccggccgcgcaacccgccaagccggccgccgcc
aagcccgccgccgcgaagccggccgccgcggcgacgaagccggccgccgagccggagagc
aagcagctgcggggcgccgcggccgcgatcgccaagaacatggacgcctcgctggccgtg
ccgaccgccaccagcgtgcgcgcggtcccggccaagctgatggccgacaaccgcatcgtc
atcaacaaccacctcaagcgcacccgcggcgggaagatctcgttcacgcacctcatcggc
tacgccatggtgcgggcgctgcaggacttcccgaacatgaaccggcactacgccctggtc
gacggcaagccgcacgccgtcacgccggagcacgtgaacctcggcctcgccatcgacatg
aagggcaaggacggggggcgcgcgctggtcgtcgcctcaatcaagaactgcgagaacatg
acgttccgccagttctggcaggcctacgaggacatcgtcaagaaggcccgcaacaacaag
ctgaccgcggacgacttcgcgggcaccaccatttcgctgaccaacccgggcggcatcggc
accaaccactcggtgccgcggctgcaggccgggcagggcgcgatcatcggcgtcggcgcc
atgcagtacccggcgcacttcgagggcaccagcgaggagaccctcgtcaagctgggcatc
agcaagatcatgacgctgacctcgacctacgaccaccgcatcatccagggtgccgagtcg
ggcgagtacctcaagcgcatccacgagttgctgctcggcgaggacggcttctacgacgac
atcttcacgtcgctgcggctgccctacgagccggtccgctgggtctccgacatccccgag
ggcgagatcgacaagaccgcccgggtactggagctgatcgacgcgtaccggatgcgcggc
cacctgatggccgacaccgacccgctgaactaccgccagcgccgccacgaggacctggac
gtcctctcgcacggcctgaccctgtgggacctggaccgcgagttcgcggtcggcgggttc
gccggccagcagaagatgaagctgcgcgacgtgctgggcgtgctgcgtgactcctactgc
cggaccgtcggcgtcgagtacacccacatcctggacccggaggagcgccgctggatccag
gaccgcgtggaggtcccgcacgccaagccggaccccaatgtccagaagtacatcctgtcg
aagctgaacgcggccgaggcgttcgagacgttcctgcagacgaagtacgtcggccagaag
cggttctcgctggagggcggcgagaccgtcatcccgatgctggacaccgtcctggacaag
gccgccgagcacgagctcgacgaggtcgtcatcggcatgccgcaccgcggccgcctcaac
gtgctggccaacatcgtcggcaagccgatctcgcagatcttccaggagttcgagggcaac
ctcgacccgggccaggcgcacggctccggcgacgtgaagtaccacctgggcgcggagggc
aagtacttccgcatgttcggcgacggcgagacccgggtgtcgctgaccgcgaacccgtcg
cacctggagaccgtcgacccggtgctcgaaggcatcgtccgcgcgaagcaggacatcctc
gacaagggcgacagcgacaccggcggcttctcggtgctacccgtgctgctgcacggtgac
gcggcgttcgccggccagggtgtcgtggcggagacgctgaacctggcgctgctgcgcggc
taccgcaccggcggcaccgtgcacatcatcatcaacaaccaggtcggcttcaccaccgca
ccggagcactcgcggtcttcgcagtacgcgacggacgtggcgaagatgatcggcgccccg
atcttccacgtgaacggcgacgacccggaggcagcgcactgggtggccaagctggccgtc
gactaccgccaggcgttcaacaaggacgtcgtcatcgacatgatctgctaccgccgccgc
ggccacaacgagggcgacgacccgtcgatgacgcagccggcgatgtacgacatcatcgac
acgaagcgttcggtgcggaagacctacaccgagtcgctgatcggccgcggtgacatctcg
gtcgaggaggccgaggccgcgctgcgggacttctcgagccagctggagcacgtcttcaac
gaggtccgcgagctggagaagcacccgatcgcaccgagcccctccgtcgaggaggagcaa
caggtgcccgcgaaggtgccgaccgcggtgcccgccgaggtgatcgagcggatcggtgac
gcgttcgtcaacgtccccgagggcttcaccccgcacccgcgcgtcaagccggtcatggag
cggcggtacaagatgtcccgcgagggcggcgtcgactgggccttcggcgagctgctcgcg
ttcggttcgctggcgatggagggccgcctggtgcggctgtccggccaggactctcgccgc
ggcacgttcacgcagcgccactcggtgctgatcgaccgcaagaccggccgggagtacgcg
ccgctgcagaacctggccgaggaccagggccgcgtgatgatctacgactcggccctgtcc
gagtacgcggcggtcggtttcgagtacggctactcggtggccaacagcgacgcgctcgtg
ctgtgggaagcccagttcggcgacttcgtcaacggcgcccagacggtcatcgacgagtac
atctcgtccggtgaggcgaagtggggccaacggtcggacgtcgtgctgctgctgccgcac
ggccacgagggccagggcccggaccacacgtcgggccgcatcgagcggttcctgtcgctg
tgcgccgaggggtcgatgaccgtggcggtcccgtcgaccccggcgaactactttcacctg
ctgcgacgccacgcgctggacggcatccagcgcccgctgatcgtcttcacgccgaagtcg
atgctgcgcaacaaggcggcgacgtccggcctggaggacttcaccggcgactcgaagttc
atgtcggtgatcgacgacgccgaggtggagcccggcaaggtccggaaggtgctgctgacc
tccggcaagctctactgggagctggtggccgagcgggccaagcgcgacgccgacgatgtg
gccatcgtgcgcatcgagcagtactacccgctgccgaagaagaagctgctggcggcgctc
gagcgctacaccggcgccgaggtcgtgtgggtccaggaggagcccgagaaccagggcgcg
tggccgttcttcggcctccacctgccgcgcatgttcccggacgtgctcggcaagctggac
gtcgtctcgcggcgtccgatggccgccccgtcggccggctcgtcgaaggtgcacgaggtg
gagcagaaggcgctgatcgccaaggccttcagctga
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