KEGG   Actinoplanes missouriensis: AMIS_50640
Entry
AMIS_50640        CDS       T01795                                 
Name
(GenBank) putative beta-ketoacyl synthase alpha subunit
  KO
K05551  minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
ams  Actinoplanes missouriensis
Pathway
ams00253  Tetracycline biosynthesis
ams01056  Biosynthesis of type II polyketide backbone
ams01100  Metabolic pathways
ams01110  Biosynthesis of secondary metabolites
Module
ams_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:ams00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    AMIS_50640
   00253 Tetracycline biosynthesis
    AMIS_50640
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:ams01004]
    AMIS_50640
   01008 Polyketide biosynthesis proteins [BR:ams01008]
    AMIS_50640
Enzymes [BR:ams01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     AMIS_50640
    2.3.1.260  tetracycline polyketide synthase
     AMIS_50640
Lipid biosynthesis proteins [BR:ams01004]
 Polyketide synthase
  Component type
   AMIS_50640
Polyketide biosynthesis proteins [BR:ams01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     AMIS_50640
    Nonaketide PKS
     AMIS_50640
    Decaketide PKS
     AMIS_50640
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C Thiolase_N
Other DBs
NCBI-ProteinID: BAL90284
UniProt: I0HB97
LinkDB
Position
5366722..5367987
AA seq 421 aa
MSRRVVLTGIGVRAPGGAGTGEFWDLLTSGRSATRRISFFDPAPFRSQIAGECDFDPAAE
GLSAREIRRMDRAAQLAVVCARSAVAASGLAVDRLDPYRIGVVLGSAVAAATSLDNEYVV
MSDSGRAREVDPDYLSPHMFDHMTPGIMPAEVAWTVGAEGPVTMISNGCTSGLDAVGHAA
QLIREGAADVMVTGATDAPITPIVVASFDAIRATTPRNDDPEHASRPFDATRNGFVLAEG
SAMFVLEERAHALARGAHVYAELSGYATRSNAYHMTGLKPDGREMAAAITAALDDGRHDP
TDVHYVNAHGSATKQNDRHETAAFKRALGEHAYRTPVSSIKSMVGHSLGAVGAIELAACA
LAIEHQVVPPTANLHERDPECDLDYVPLTAREQRVDTVLSVGSGFGGFQSAVVLTRTGGD
R
NT seq 1266 nt   +upstreamnt  +downstreamnt
atgtcccgtcgtgtcgtgctgaccggaatcggggttcgcgcaccgggcggagccggaacc
ggagaattctgggacctgctgacctccggccgcagcgccacccgccgtatcagcttcttc
gaccccgcgccgttccggtcccagatcgccggggagtgtgacttcgacccggcggccgag
gggctctccgcccgcgagatccggcggatggaccgggcggcccagctcgccgtcgtctgt
gccaggtccgcggtcgccgccagcggtctcgccgtggaccggctcgacccgtaccggatc
ggggtggttctgggcagtgcggtcgccgccgccaccagcctcgacaacgagtacgtggtg
atgtcggactccggccgtgcccgcgaggtcgaccccgattatctgtccccgcacatgttc
gaccacatgacgcccgggatcatgccggccgaggtggcctggacggtcggcgccgagggc
ccggtcaccatgatctccaacggctgcacctcggggctggacgcggtgggacacgccgcc
cagctcatccgcgagggcgcggccgacgtcatggtcaccggcgccaccgacgcgccgatc
acgcccatcgtggtggccagcttcgacgctatccgggcgaccacgccccgcaacgacgac
ccggagcacgcctcccgtccgttcgacgccacccgcaacgggttcgtgctggccgagggc
tcggcgatgttcgtgctggaggagcgcgcgcacgcgctggcccgcggcgcccacgtctac
gccgagctgagcgggtacgccacccggtcgaacgcgtaccacatgaccggcctcaagccc
gacggccgggagatggcggccgcgatcaccgccgccctcgacgacggccggcacgacccc
accgacgtgcactacgtcaacgcgcacggctcggccaccaagcagaacgacaggcacgag
accgccgccttcaaacgcgcgctgggcgagcacgcgtaccggacgccggtcagctcgatc
aagtcgatggtcgggcactcgctcggcgcggtcggcgcgatcgaactggccgcctgcgcc
ctggcgatcgagcaccaggtggtgccgcccaccgcgaatctgcacgaacgcgatccggag
tgcgacctcgactacgtgccgctcaccgcccgtgagcaacgggtggacaccgtgctcagc
gtgggcagcgggttcggcggattccagagcgcggtggtgctgacacgtaccggaggagac
cgatga

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