KEGG   Akkermansia muciniphila: Amuc_1961
Entry
Amuc_1961         CDS       T00736                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
amu  Akkermansia muciniphila
Pathway
amu00270  Cysteine and methionine metabolism
amu00450  Selenocompound metabolism
amu00670  One carbon pool by folate
amu01100  Metabolic pathways
amu01110  Biosynthesis of secondary metabolites
amu01230  Biosynthesis of amino acids
amu04980  Cobalamin transport and metabolism
amu04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:amu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Amuc_1961
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Amuc_1961
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Amuc_1961
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Amuc_1961
   04980 Cobalamin transport and metabolism
    Amuc_1961
Enzymes [BR:amu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Amuc_1961
SSDB
Motif
Pfam: S-methyl_trans Met_synt_B12 Pterin_bind B12-binding_2 B12-binding MtrH EipA Deltameth_res MIT
Other DBs
NCBI-ProteinID: ACD05774
UniProt: B2UNQ8
LinkDB
Position
2377647..2381408
AA seq 1253 aa
MSRASRTERLDYLKDQLRKRVVILDGAMGTNIQKFRLGEGDYRGERFADAECYPNDLKNN
NDLLVLTRPDIILDIHRRFLDTGRTDILETCTFGATSIGQHDYFWHRPEEGSHKDQQYFQ
EVVDAPELKALVRELNLAAAALARQACDEAEAADGKPRLVAGSIGPMPVTCSLSPDVNDP
GFRAVNFRQLRQAYRDQVLALLEGGVDMLLVETIFDTLNAKAALFAIEEIFEEQPESSVP
VMVSVTLTDKAGRTLSGQTIEAFWNSIRHVRPFSVGINCALGPDLMRPFAEELSGLADCH
MSIYANAGLPNPLSPTGYDLLPADMARFMKEYAEQGLLNIVGGCCGTTPEHIGAIAAAVE
GMPPRVPAPQTPALRLSGYEAYNHTREKNTLFVGERCNVAGSPKFARLIREGNYEEAVSI
ARQQVENGALVLDFCFDDGLIDGPQAMVRFLNLVSAEPDIARVPFMVDSSKWEVLEAGLQ
CMQGKGIVNSISLKEGEEEFLKKAALIKKYGAAVVVMAFDEQGQAANYEDRVRISRRAYD
LLVNRVQFPPEDIIFDPNVLTVGTGIAEHADYALDFFKAAGWISRNLPHAHISGGISNVS
FAFRGNNPVREAMHSAFLYHATQQGLDMCIVNAGMLEVYDNIPKDRLELIEDVLLNRRTD
ATERLTDYAEKLAAEKTGDGKEKKTVQAWREQDVAKRLEYSLIKGITEFVDADTEEAFQE
LGSPLNVIEGPLMAGMKVVGQLFGDGKMFLPQVVKSARVMKQAVAWLTPYIEADSKGAAK
AGKAVIATVKGDVHDIGKNIVGVVLSCNGFEMIDLGVMVHCDTILDRAEAEQADLVMLSG
LITPSLEEMSHVAAEMERRGMTIPLMVGGATTSALHTALKIAPHYQGAVVHTEDASQVVP
AAASLVGEKKDSYIAAVKARQEELRNNHENKPVRDLLPLEKARELRWKGAEGGYLPPVPA
RLGPVSIGSLHSSVSCGCCSDDPRYYVTVQELIERMDWTPFFHAWELHGTWDRARREFRT
KDPSKAEAAAALYQDALRLLEQAVKENRYQARGVIGIFPANSTASHDDITVWADESRTIP
LATLLTQRQQLDKQGKPRLALADFIAPEGVRDYVGAMAVSIHGSRRWAKEWEARNDSYRA
LLVSSLADRLVEAFAAIAHDKLRLLWNIPEGSGVRPACGYPSQPDHQEKETVFTLLHARE
EAGMSLTETWMMQPVSSVCALVFSHPESTYFSVGVTGEDQQEDYASRKRASRP
NT seq 3762 nt   +upstreamnt  +downstreamnt
atgagcagagcatccagaacagaacgccttgattacctgaaagaccagttacgtaaaagg
gttgtcatcctggatggcgccatgggcaccaatatccaaaaattcaggctgggagaggga
gattaccgcggagaacgttttgcggatgcggaatgctatcccaacgatttaaagaataat
aacgaccttctggttctgaccaggccggatatcattcttgatattcaccgccgctttctt
gacacgggacggacggatattctggaaacctgcacattcggagctaccagcatcggccag
catgattatttctggcaccgtccggaggaaggcagccacaaggaccagcagtatttccag
gaagtggtggacgcccccgaattgaaggcccttgtccgggaattgaatttggcggcagcc
gcactggcccggcaggcatgcgacgaagcggaagctgcagacggcaagccccgcctggtg
gccgggtccatcggccccatgcccgtcacctgttccctgtcccccgacgtgaatgatccc
ggtttccgcgccgtgaatttccgccagctcaggcaggcgtaccgggatcaggtgctggcc
ctgctggaagggggggtggacatgctgctggtggagacgattttcgacacgctgaacgcc
aaggcagccctgttcgccattgaagaaatttttgaggaacaaccggaaagctctgttccg
gtcatggtatccgtaacgctgacggacaaagccggacgcacgctgtccggccagacgatt
gaagcattctggaactccatccgccacgttcgccccttctccgtaggcatcaattgcgcc
ctggggccggacctgatgcgcccctttgcggaagaactgtccggactggcagattgccac
atgtccatttatgcgaatgccgggcttcccaacccgctcagccctaccggctacgacctt
ctgccggcggatatggcccggttcatgaaggaatacgcggaacagggcctgctgaacatc
gtgggcggctgctgcggaaccactccggagcatatcggcgccattgcggctgccgtggaa
ggaatgcctccgcgcgttccggctccccaaacgcccgcgcttcgcctgtccggatatgaa
gcgtacaaccatacgcgggaaaaaaacaccctctttgtcggggaacgctgcaatgtggcg
ggttcccccaaattcgcccgcctgattcgtgaaggaaattacgaggaagcggtatccatt
gcccggcagcaggtggaaaacggcgcgctggtattggatttctgttttgacgacggcctg
atcgacgggccgcaggccatggtccgcttcctgaaccttgtttccgcagagccggatatc
gcccgcgttcctttcatggtggattcctccaagtgggaggtgctggaagcggggctccaa
tgcatgcagggcaagggaatcgtgaattccatttctctgaaggagggggaagaagaattc
ctgaagaaagcggcgctgattaaaaagtacggcgcagcggtcgtggtcatggcgtttgac
gaacagggacaggccgccaattacgaggaccgcgtccgcatctccagacgggcctatgac
ttgctggtaaaccgggtgcagtttcctccggaagacatcatttttgacccgaacgtcctg
accgtaggcaccggcattgcggaacacgccgattacgctcttgatttcttcaaggccgca
ggctggatctcccggaacctgccgcatgcccacatttccggcggcatttccaatgtctcc
tttgctttccgcggcaacaacccggtgcgggaagccatgcattccgctttcctgtaccac
gctacgcagcaggggctggacatgtgcatcgtgaatgccgggatgctggaggtgtacgac
aatattcccaaggacaggctggagctgattgaagacgttctgctgaaccggaggacggac
gccacggaacgcctgacggattacgcggaaaaactggctgcggaaaaaaccggagacgga
aaggagaaaaaaaccgtacaggcctggagggagcaggacgttgccaaacgtctggaatat
tctcttatcaagggcattaccgaatttgttgacgcggatacggaggaggcttttcaggag
ctggggtctccgctgaacgtgattgaaggccctctgatggccggcatgaaggtcgtcggg
caactgttcggggacggcaaaatgttcctgccgcaggtggtgaaaagcgcccgcgtcatg
aaacaggctgtagcctggctcaccccctatatagaagcggacagcaaaggagccgccaag
gcgggaaaagccgtgatcgccaccgtgaagggggacgtgcatgacatcggcaaaaatatc
gtcggcgtggtgttgagctgcaatggttttgaaatgattgacctgggcgtcatggtccat
tgcgataccattctggaccgggcggaagcggaacaggcggacctggtgatgctttccggg
ctgatcaccccttccctggaagagatgtcccatgtagccgcggagatggaacgccggggg
atgaccattcccctgatggtggggggagctacgacgtcagccctgcatacggccctgaaa
atagccccccattatcaaggagccgtggtgcatacggaggatgcctcccaggtggttccc
gcagccgcctccctggtgggagaaaaaaaggattcctacattgccgccgtgaaggcccgg
caggaggaattgcgcaacaatcatgaaaacaaacccgtccgggacctcctgcccctggag
aaagccagggaattgcgctggaagggagcggaaggcggctatctcccccccgttcccgcc
cgtcttggcccggtttccatcggcagcctgcacagctccgtaagctgcggctgctgcagt
gacgatccacgttattacgtaactgttcaggagcttatcgagcgcatggactggacgcct
tttttccacgcctgggagctgcacggcacatgggaccgcgcccgccgggagttccgcacc
aaagacccgtccaaggctgaggcggccgcggcgctgtaccaggacgccctccgcttgctg
gaacaggccgtgaaggaaaaccgctaccaggcgcgcggcgtcataggcattttcccggcc
aattcaacagccagccatgacgacatcaccgtctgggctgatgaatccagaaccattccc
ctggctacgctgctgacgcagcgccagcaactggacaaacaggggaaaccccggctggcg
ctggcggacttcatcgctcccgaaggcgtcagggattacgtgggggccatggcggtcagc
atccacggctcccgccgctgggcaaaggaatgggaagccagaaacgactcctaccgcgcc
ctgctggtcagctctctggcggaccgcctggtggaggctttcgcggccatcgcccatgac
aagctgcgccttttgtggaatattccggaagggtccggcgtgcgacctgcctgcgggtac
cccagccagccggaccaccaggaaaaggaaaccgtcttcaccctgctccacgcccgggag
gaagcgggcatgagcctgacggaaacatggatgatgcagcccgtttcttccgtctgcgcc
ctcgtcttctcccatccggaaagcacttatttctccgtgggcgtcaccggggaagaccag
caggaggattacgcctccagaaaacgggcctcccggccctga

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