Amycolatopsis sp. AA4: CU254_13920
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Entry
CU254_13920 CDS
T05278
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
amyc
Amycolatopsis sp. AA4
Pathway
amyc00909
Sesquiterpenoid and triterpenoid biosynthesis
amyc01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
amyc00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
CU254_13920 (shc)
Enzymes [BR:
amyc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
CU254_13920 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
CU254_13920 (shc)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
TED_complement
Prenyltrans
Motif
Other DBs
NCBI-ProteinID:
ATY11433
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All DBs
Position
complement(2951853..2953763)
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AA seq
636 aa
AA seq
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MTQTVPRTAASAPAARTAADTVAAAVQFLRREQDRAGWWKGELATNVTMDAEDLLLRHFL
GILTPQIAEESARWIRSQQRADGTWANFPDGPADLSTTVEAWVALRLAGDPADAPWLATA
AEWIREHGGIEATRVFTRIWLAMVGQWSWDDLPSLPPELIFLPSWFPLNVYDFACWARQT
IVPLTIVGTLRPARKLPFDVAELRTGKRPPKPRAPWTWDGVFQNLDTALHAYAKLPLNPV
RKLALKQAAEWILARQEADGSWGGIQPPWVYSILALHLLGYSLDHPALKAGIAGLDGFTI
REKTDQGWVRRLEACQSPVWDTALAMTALLDAGVSPGDESLVRAAEWMLGEEIRVPGDWA
VRRPSLKPGGFAFEFANDGYPDTDDTAEVVLALRRMGKPDHLRIREAVDRSVAWLEGMQS
SDGGWGAFDADNTQVLTTRLPFCDFGAVIDPPSADVTAHVVEMLAAEGKADTRECRRGIR
WLWDNQEADGSWFGRWGANYVYGTGAVVPALVAAGVPGTDPRIRRAVRWLAEHQNDDGGW
GEDLRSYDDRSWAGRGDSTPSQTAWALLALLAAGERESTVVARGVEWLCERQRPDGGWDE
DKHTGTGFPGDFYLSYHLYRVVFPLSALGRYVRGGS
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atgacccagaccgtcccccggaccgccgcctccgcgcccgccgcccgcaccgccgccgac
acggtcgccgcggcggtccagttcctgcgccgcgagcaggaccgtgccggatggtggaag
ggcgaactcgccaccaacgtcacgatggacgccgaagacctgctgctgcggcatttcctc
gggatcctcacgccgcagatcgccgaggagtcggcgcgctggatccgctcgcagcagcgc
gccgacggcacctgggcgaacttcccggacggcccggctgacctctccacgacggtcgag
gcgtgggtcgcgctgcggctggccggcgacccggcggacgccccgtggctggccacggcc
gcggagtggatccgcgagcacggcgggatcgaggcgacccgggtgttcacccggatctgg
ctcgcgatggtcggccagtggtcgtgggacgacctgccgagcctgccgccggagctgatc
ttcctgccgtcgtggttcccgctcaacgtctacgacttcgcgtgctgggcccggcagacc
atcgtgccgctgaccatcgtcggcacgctgcgcccggcgcggaagctgcccttcgatgtc
gccgagctgcgcaccggcaagcgaccgccgaagccgcgcgcgccgtggacgtgggacggc
gtgttccagaatctcgacaccgcgctgcacgcgtacgcgaaactgccgctcaacccggtg
cggaagctcgcgctcaagcaggcggcggagtggattctcgcgcggcaggaggccgacggt
tcgtggggcgggatccagccgccgtgggtgtactcgatcctcgcgctgcacctgctcggc
tattcgctcgaccatcccgcgctcaaggccgggatcgccgggctcgacggattcaccatc
cgggagaagaccgaccagggctgggtgcggcggctcgaagcgtgccagtcgccggtgtgg
gacaccgcgctggcgatgaccgcgctgctcgacgcgggcgtgtcccccggcgacgaaagc
ctggtccgggccgcggagtggatgctgggcgaggaaatccgggtcccgggagactgggcg
gtgcggcggccttcgctgaagcccggcgggttcgcgttcgagttcgccaacgacggctac
ccggacaccgacgacaccgccgaggtggtgctcgcgctgcggcggatgggcaaaccggat
cacctgcggatccgcgaggcggtcgaccggagcgtcgcgtggctggaggggatgcagtcc
agcgacggcggctggggcgcgttcgacgcggacaacacacaggtgctgacgacgcggttg
ccgttctgcgatttcggcgcggtgatcgacccgccgtcggcggacgtgaccgcgcacgtg
gtcgaaatgctggccgcggaagggaaagcggacacccgcgaatgccgtcgcgggatccgg
tggctatgggacaaccaggaggcggacggttcgtggttcggccggtggggcgcgaactac
gtgtacggcacgggcgcggtggtgcccgcgctggtcgcggccggggtccccgggaccgat
ccgcggatccggcgggcggtgcggtggctggccgagcaccagaacgacgatggcggatgg
ggcgaggacctgcggtcgtacgacgatcgatcgtgggccggacgtggtgattcgacgcct
tcgcagacggcgtgggcattgctggcgttgctggctgccggagagcgagagtccacagtg
gtcgcccggggcgtcgagtggctgtgcgaacggcagcgtccagacggtggctgggacgag
gacaagcacaccgggaccggcttcccgggcgacttttacctgtcgtatcacctgtatcgc
gtggtgttcccgctgtccgcgctcggccggtacgtacggggcgggtcatga
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