KEGG   Amycolatopsis sp. AA4: CU254_22050
Entry
CU254_22050       CDS       T05278                                 
Name
(GenBank) pyruvate dehydrogenase
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
amyc  Amycolatopsis sp. AA4
Pathway
amyc00010  Glycolysis / Gluconeogenesis
amyc00020  Citrate cycle (TCA cycle)
amyc00620  Pyruvate metabolism
amyc00785  Lipoic acid metabolism
amyc01100  Metabolic pathways
amyc01110  Biosynthesis of secondary metabolites
amyc01120  Microbial metabolism in diverse environments
amyc01200  Carbon metabolism
amyc01210  2-Oxocarboxylic acid metabolism
Module
amyc_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:amyc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    CU254_22050
   00020 Citrate cycle (TCA cycle)
    CU254_22050
   00620 Pyruvate metabolism
    CU254_22050
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    CU254_22050
Enzymes [BR:amyc01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     CU254_22050
SSDB
Motif
Pfam: Transketolase_N Transketolase_C_1 PDH_E1_M Transketolase_C DXP_synthase_N NdhN
Other DBs
NCBI-ProteinID: ATY12834
UniProt: A0A2K8LWN8
LinkDB
Position
4734511..4736826
AA seq 771 aa
MSSAAPERLPDNDTVTVLREVQDRVLWLSAAIIDHANRVRPNPTGLKVGGHQASSASMVS
IMTALWFARLRAEDRVSVKPHASPVLHAINYLLGDLDEKYLTTLREFGGLQSYPSRSKDP
DQVDYSTGSVGIGATAPIWGALARRYVESHGGGAGTGRQYSLVGDAELDEGACWEAILDP
NVAELGEVVWIVDLNRQSLDRVVPNIGATRLQGMFEAAGWQVLTVKYGRLLQELFERPGG
SALRRRIDEMPNPEYQRLLRCTPAQLRERLATPELAPLLDTLDDETLHAAIRNLGGHDLS
ALLDTFDAIDDHRPTVVFAYTVKGFGLASEGHPQNHSSLLTAEQLGALAERVGISPENPW
QKFADGSAAAQLCASTAARLKRGPVELQPVPALPSDIGRTPSGRTTTQAALGRALLDLTR
EAPEAAELVVTLCPDVSSSTNLGGWVNKVGVWSPQERVDWFADDPETILHWRERPSGQHL
ELGIAEVNLVSALGELGTTWSRWGRPLLPIGVLYDPFVERALEPWSFGIYGGGQSILVGT
PSGVTLAPEGGAHQSVTTPSVGLEQPGCVTYEPAFALDVEWTLLASLSRLGRPDGTSAYL
RLSTRPVDQSLAAVPTDPAARERRRRQVVAGAYPIRTAAVARPDVTLVTMGAMVTEALEA
ASRLDALGKHADVVCVTSPGLLFRAVQARAGQDTADTWILESALPSERSAPMVTVLDGHP
HTLAFLANVHRVRAAHLGVTRFGQSGDLESVYRHHGIDTDSIIQAALDVAD
NT seq 2316 nt   +upstreamnt  +downstreamnt
gtgagcagcgccgcccccgaacgccttccggacaacgacacggtgaccgtcctgcgcgag
gtgcaggaccgggtgctgtggctgtcggccgcgatcatcgaccacgcgaaccgggtgcgg
ccgaatccgaccgggctcaaggtcggcgggcaccaggcgtccagcgcctcgatggtgtcg
atcatgaccgcgctgtggttcgcccggctgcgcgcggaggaccgcgtttcggtcaaacca
cacgcctcccccgtgctgcacgcgatcaactacttgctcggcgacctcgacgagaagtac
ctgacgacgctgcgcgagttcggcggcctgcagagctacccgtcgcgctcgaaggacccg
gaccaggtcgactactccaccggctcggtcggcatcggcgcgaccgccccgatctggggc
gcgctcgcccgccgctacgtcgaatcgcacggcggcggcgcgggcaccgggcggcagtac
tcgctggtcggcgacgcggagctggacgagggcgcgtgctgggaggccatcctcgacccg
aacgtggccgaactcggcgaggtcgtctggatcgtcgacctgaaccggcagtcgctcgac
cgcgtggtcccgaacatcggcgcgacccggctgcagggcatgttcgaggcggccggctgg
caggtgctgaccgtgaagtacgggcggctgctgcaggaactgttcgaacggccgggcggc
tccgcgctgcgccggcgcatcgacgagatgccgaacccggagtaccagcgcctcctccgg
tgcaccccggcccagctgcgcgaacgcctggccacgccggaactggctccgctgctcgac
accctcgacgacgaaacgctgcacgccgccatccgcaacctcggcggccacgacctgtcc
gcgctgctggacacgttcgacgccatcgacgaccaccggccgacggtcgttttcgcttac
acggtcaagggattcggcctggcgagcgaaggacatccgcagaaccactcgtcgctgctg
accgccgagcagctgggtgcgctggccgaacgcgtcgggatttcgccggagaacccgtgg
cagaagttcgccgacggctccgcggccgcccagctgtgcgcctcgaccgccgctcgcctg
aagcggggacccgttgagctgcaaccggttccggctctgccgtccgacatcggccgcacg
ccgtccggccgcaccacgacgcaggccgccctcggccgcgcactgctcgacctgacccgc
gaagctcccgaggcagcggaactcgtcgtgacgctgtgtccggacgtctcgtccagcacc
aacctcggcggctgggtcaacaaggtcggcgtgtggtcgccgcaggaacgcgtcgactgg
ttcgccgacgacccggagacgatcctgcactggcgcgagcggcccagcggacagcatctg
gaactgggcatcgccgaggtgaacctggtgagcgcgctcggggaactgggcacgacgtgg
tcgcgctggggccgcccgctgctgccgatcggggtgctctacgaccccttcgtggagcgc
gcgctggaaccgtggtcgttcgggatctacggcggcggacagtccattttggtcggcacc
ccgtccggcgtcacgctcgcgcccgagggcggtgcgcaccagtcggtgaccacgccgtcg
gtcgggctggaacagccgggctgcgtgacgtacgaacccgcgttcgcgctggacgtcgag
tggaccctgctggcgtccctttcgcggctcggccgccccgacggcacctcggcgtacctc
cggctctcgacccgcccggtggaccagagcctggccgcggtgccgaccgacccggccgcg
cgggagcgccgtcgccgccaggtcgtggcgggcgcgtacccgatccgcaccgccgcggtg
gcgcgcccggacgtcacgctggtgacgatgggcgcgatggtcaccgaggcgctggaagcc
gcctcccggctggacgcgctgggcaagcacgccgacgtcgtgtgcgtgacgagccccggc
ctgctgttccgcgccgtgcaggcccgggcgggccaggacaccgccgacacgtggatcctg
gagtcggcgctgccgtccgaacggtccgcgccgatggtgacggtgctcgacgggcacccg
cacacgctggcgttcctggcgaacgtccaccgcgtgcgggcggcgcacctgggcgtgacg
cggttcgggcagtcgggcgatctggagagcgtgtaccggcaccacggcatcgacacggac
agcatcatccaggcggcgctggacgtcgcggactga

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