Amycolatopsis sp. AA4: CU254_32270
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Entry
CU254_32270 CDS
T05278
Symbol
kgd
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
amyc
Amycolatopsis sp. AA4
Pathway
amyc00020
Citrate cycle (TCA cycle)
amyc00630
Glyoxylate and dicarboxylate metabolism
amyc00785
Lipoic acid metabolism
amyc01100
Metabolic pathways
amyc01110
Biosynthesis of secondary metabolites
amyc01120
Microbial metabolism in diverse environments
amyc01200
Carbon metabolism
amyc01210
2-Oxocarboxylic acid metabolism
Module
amyc_M00009
Citrate cycle (TCA cycle, Krebs cycle)
amyc_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
amyc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CU254_32270 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
CU254_32270 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CU254_32270 (kgd)
Enzymes [BR:
amyc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CU254_32270 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CU254_32270 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CU254_32270 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CU254_32270 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
DUF3007
Motif
Other DBs
NCBI-ProteinID:
ATY14575
UniProt:
A0A2K8M9M7
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All DBs
Position
6991167..6994856
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AA seq
1229 aa
AA seq
DB search
MASSSPASQFGANEWLVEEMYERFLADPQSVDAAWHDFFADYKPTPGGNGTQAGENGEVK
SSAPAPAAKPAPAAKSSAAPAAKAPAAKAPAAKAPAAKSAPAAKAAPAEKPAPAKTAPES
KQLRGAAAAIAKNMDASLAVPTATSVRAVPAKLMADNRIVINNHLKRTRGGKISFTHLIG
YAMVRALKDFPNMNRHYQLIDGKPFAVTPEHVNFGLAIDMKGKDDSRTLVVASIKATENM
TFMQFWQAYEEIVKKARTNKLTADDFAGTTISLTNPGGIGTNHSVPRLQAGQGAIIGVGA
MQYPASFEGTSEKTLVDLAVSKIMTLTSTYDHRIIQGAESGEFLKRIHELLLGEDGFYDD
VFTSLRLPYEPIRWVADIPDGPVDKTARVMELIEAFRMRGHLMADTDPLNYRQRSHHDLD
VLSHGLTLWDLDREFAVGDFSSRERMKLRDILGVLRDSYCRTVGVEYTHILDPEERGWIQ
ERVEVRHSKPEPSAQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGGETAIPLLDTILDK
AAEHELDEVVIGMPHRGRLNVLANIVGKPISQIFQEFEGNLDPGQAHGSGDVKYHLGAEG
KYFRMFGDGETRVSLASNPSHLETVDPVLEGIVRAKQDILDKGGEGYTVLPVLMHGDAAF
AGQGVVAETLNLALLRGYRTGGTVHVIVNNQVGFTTAPEHSRSSQYATDVAKMIGAPVFH
VNGDDPEAAYWVAKLAVDYRQAFHKDVVIDLVCYRRRGHNEGDDPSMTQPAMYDIIDSKR
SVRKTYTESLIGRGDISVEEAEAALRDFSSQLEHVFNEVRELERHPAKASPSVEGEQQIP
AKVATAVSREVVEKIGDAFVNLPEGFTPHPRVKPVMERRHKMSREGGIDWAFGELLAFGS
LALEGRLVRLSGQDSRRGTFTQRHSVFIDRKNGQEYSPLQHLADGQGRVMIYDSALSEYA
AVGFEYGYSVANSDALVMWEAQFGDFVNGAQTVIDEYISSGEAKWGQRSDVVLLLPHGHE
GQGPDHTSGRIERFLSLCAEASMTVAVPSTPANYFHLLRRHALDGIQRPLIVFTPKSMLR
NKAATSSVEDFTGQSRFMSVIDDATQDPAKIRKVLLTSGKLYWELVAEREKRGADDVAIV
RIEQYYPLPKKKLLAAVERYTNAQQIAWVQEEPENQGAWPFFGLNLPRKFPEFFGGLDVV
ARRPMAAPSAGSSKVHEVEQKALIAKAFD
NT seq
3690 nt
NT seq
+upstream
nt +downstream
nt
gtggccagcagcagtcccgcatcgcagttcggtgccaatgagtggctcgtcgaggaaatg
tacgagcggtttctcgcggacccccagtcggtagacgccgcctggcacgatttcttcgcc
gactacaagcccactccgggcggcaacggcacgcaggcgggagagaacggagaggtcaag
tcctccgctccggcccccgcggccaagcccgcgccggccgcgaagtcctcggccgccccc
gcggccaaggcgcccgccgccaaggctccggcggcgaaggccccggccgccaagagcgcg
ccggccgcgaaggccgccccggccgagaagcccgctccggccaagaccgccccggaatcc
aagcagctccgcggtgccgcggcggcgatcgccaagaacatggacgcctcgctcgccgtg
ccgaccgcgaccagcgtgcgcgccgtgccggcgaagctgatggcggacaaccgcatcgtc
atcaacaaccacctcaagcgcacccgcggcggcaagatctccttcacgcacctcatcggc
tacgccatggtgcgggcgctgaaggacttcccgaacatgaaccggcactaccagctgatc
gacgggaagccgttcgcggtcacgccggagcacgtgaacttcggcctcgcgatcgacatg
aagggcaaggacgactcccgcactctcgtcgtggcctcgatcaaggccaccgagaacatg
accttcatgcagttctggcaggcctacgaggagatcgtcaagaaggcccgcacgaacaag
ctcaccgcggacgacttcgcgggcaccaccatctcgctcaccaacccgggcggcatcggc
accaaccactcggtgccgcggctgcaggcgggccagggcgcgatcatcggcgtcggcgcg
atgcagtacccggcgtcgttcgagggcaccagcgagaagaccctggtcgacctcgcggtc
agcaagatcatgacgctgacctcgacctatgaccaccgcatcatccagggcgcggagtcc
ggcgagttcctaaagcgcattcacgaactgctgctcggcgaggacggcttctacgacgac
gtcttcaccagcctgcggctgccgtacgagccgatccgctgggtcgccgacatcccggac
ggcccggtcgacaagaccgcgcgcgtcatggagctgatcgaggcgttccggatgcgcggc
cacctgatggccgacaccgacccgctgaactaccgccagcgcagccaccacgacctggac
gtgctcagccacggcctgaccctgtgggacctggaccgcgagttcgccgtcggcgacttc
tccagccgcgagcggatgaagctgcgcgacatcctcggcgtgctgcgcgactcgtactgc
cgcacggtcggggtggagtacacgcacatcctcgaccccgaggagcgcggctggatccag
gagcgcgtcgaggtccggcacagcaagccggagccgtccgcgcagaagtacatcctgtcg
aagctcaacgccgccgaggcgttcgagaccttcctgcagaccaagtacgtcggccagaag
cggttctcgctggagggcggcgagaccgcgatcccgctgctcgacaccatcctggacaag
gccgccgagcacgagctcgacgaggtcgtcatcggcatgccgcaccgcggccggctgaac
gtgctggcgaacatcgtcggcaagccgatcagccagatcttccaggagttcgagggcaac
ctcgacccgggccaggcgcacggttccggcgacgtgaagtaccacctcggcgccgagggc
aagtacttccggatgttcggcgacggggagacccgggtgtcgctggcgtccaacccgtcg
cacctggagaccgtcgacccggtcctcgagggcatcgtccgcgccaagcaggacatcctc
gacaagggcggcgagggctacaccgtgctgccggtcctgatgcacggcgacgcggccttc
gcgggccagggcgtcgtggccgagaccctgaacctggcgctgctgcgcggctaccgcacc
ggcggcaccgtgcacgtcatcgtcaacaaccaggtcggcttcaccaccgcgccggagcac
tcgcgctccagccagtacgccaccgacgtcgcgaagatgatcggcgcgccggtcttccac
gtgaacggcgacgacccggaggccgcgtactgggtcgcgaagctggcggtcgactaccgc
caggcgttccacaaggacgtcgtgatcgacctggtctgctaccgccgccgcgggcacaac
gagggcgacgacccgtcgatgacgcagccggcgatgtacgacatcatcgattcgaagcgt
tcggtccggaagacctacaccgaatcgctgatcggccggggcgacatctccgtcgaggag
gccgaggccgcgctgcgcgacttctccagccagctcgagcacgtcttcaacgaggtccgc
gaactggagcggcacccggcgaaggcgagcccgtcggtcgagggcgagcagcagatcccg
gcgaaggtcgccaccgccgtgtcgcgcgaggtcgtcgagaagatcggcgacgcgttcgtc
aacctgcccgagggcttcaccccgcacccgcgggtcaagccggtcatggagcgccgccac
aagatgtcccgcgagggcggcatcgactgggcgttcggcgaactgctcgcgttcgggtcg
ctggcgctggaaggccgtctcgtgcggctgtccggccaggactcccggcgcggcaccttc
acccagcggcactcggtgttcatcgaccgcaagaacggccaggagtactcgccgctgcag
cacctggccgacggccagggccgcgtgatgatctacgactcggcgctgtcggagtacgcg
gccgtcggcttcgagtacggctactcggtggcgaactccgacgcgctggtgatgtgggaa
gcgcagttcggcgacttcgtcaacggcgcgcagaccgtgatcgacgagtacatctcctcc
ggcgaggccaagtggggccagcgctcggacgtcgtgctgctgctgccgcacggccacgag
ggccagggcccggaccacacgtccggccggatcgagcggttcctgtcgctgtgcgcggaa
gcgtcgatgaccgtcgcggtgccgtccaccccggcgaactacttccacctgctgcgccgg
cacgccctcgacggcatccagcgtccgctgatcgtcttcaccccgaagtcgatgctgcgg
aacaaggcggcgacctcgtcggtcgaggacttcaccggccagagccggttcatgtcggtg
atcgacgacgcgacgcaggacccggcgaagatccgcaaggtgctgctcacctcgggcaag
ctctactgggagctggtggccgagcgcgagaagcgcggcgcggacgacgtcgcgatcgtg
cggatcgagcagtactacccgctgccgaagaagaagctgctggccgcggtggagcgctac
acgaacgcccagcagatcgcgtgggtccaggaagagccggaaaaccagggcgcgtggccg
ttcttcggcctcaacctgccgcggaagttcccggagttcttcggcgggctcgacgtggtg
gcgcggcgtccgatggccgccccgtcggcgggttcgtccaaggtgcacgaggtcgagcag
aaggcgctgatcgccaaggcgttcgactga
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integrated database retrieval system
