Amycolatopsis sp. AA4: CU254_38625
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Entry
CU254_38625 CDS
T05278
Name
(GenBank) 2-oxo acid dehydrogenase subunit E2
KO
K09699
2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:
2.3.1.168
]
Organism
amyc
Amycolatopsis sp. AA4
Pathway
amyc00280
Valine, leucine and isoleucine degradation
amyc00640
Propanoate metabolism
amyc00785
Lipoic acid metabolism
amyc01100
Metabolic pathways
amyc01110
Biosynthesis of secondary metabolites
amyc01210
2-Oxocarboxylic acid metabolism
Module
amyc_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amyc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
CU254_38625
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
CU254_38625
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CU254_38625
Enzymes [BR:
amyc01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.168 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
CU254_38625
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Motif
Pfam:
2-oxoacid_dh
Biotin_lipoyl
E3_binding
Biotin_lipoyl_2
HlyD_3
HlyD_D23
Motif
Other DBs
NCBI-ProteinID:
ATY15647
UniProt:
A0A2K8M4T4
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Position
8325128..8326519
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AA seq
463 aa
AA seq
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MPEYKQFPLSDTAEGLTEADILAWRVKPGDTVTVNQIVVEVETAKAAVELPIPWAGVVTE
LHVEPGQTVEVGTPILTVDVDPDGKASPAPAAAPAAAESAPAEEEMKPLVGYGSKAAGTT
RRARKHPNVALGASDAPNATLGASHAPNATLGQPPAPAAPAGSAAPRGGYVPLAKPPVRK
LAKDLGVDLHSLTGSADGGVITREDVHRAANGSAAPAVSTVSTVESGYDPATRERRVPIK
GVRKATAAAMVQSAYTAPHVTEFLTVDVTPMMELREKLKKSREFSGVKLTPLAFAAKAVC
LAAKRTPDVNAVWDEAAQEIVYKDYVHLGIAAATPRGLVVPKIRDADSLSLKELAVALTE
LTDVAREGKTTPAAMLGGTFTITNVGVFGVDTGTPIINPGESAILAVGAIRDTPWVVDGE
IKVRKVMQLSLSFDHRVVDGQQGSEFLADVGALLADPAVAITY
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagtacaaacagtttcccttgtcggacacggcggaggggctcaccgaggccgac
atcctcgcctggcgcgtgaagccgggcgacacggtgacggtcaaccagatcgtggtcgag
gtcgagaccgcgaaggccgccgtcgagctgccgatcccgtgggccggcgtggttaccgag
ctgcacgtggaaccggggcagacggtggaggtcgggacgccgatcctgaccgtggacgtg
gatccggacgggaaagcctcgcccgctcccgccgccgcccccgctgccgcggagtccgct
cccgccgaggaggagatgaagccgctggtcggctacggctccaaggcggccgggaccacc
cgccgggctcgaaagcaccccaatgtggcattgggtgcgtcagatgcaccgaacgccaca
ttgggtgcgtcgcatgcacccaatgccacattggggcaacccccggccccagcggcaccg
gccggatcagcggcaccgcgcggcggttacgtcccgctggccaaaccgccggttcgcaag
ctggccaaggatctcggcgtcgacctgcactcgctcaccggcagcgcggacggcggcgtg
atcacccgcgaggacgtgcaccgagccgccaatggttccgcggctcccgcagtgtccact
gtgtccactgtggagtccggctacgacccggccacccgcgagcggcgcgtgccgatcaag
ggcgtccgcaaggcgaccgcggccgcgatggtgcagagcgcgtacaccgctccgcacgtc
acggagttcctcaccgtcgacgtcacgccgatgatggaactgcgcgagaagctcaagaag
tcgcgcgaattcagcggcgtcaagctcactccgctggcgttcgcggcgaaggccgtgtgc
ctcgcggcgaagcgcacgccggacgtcaacgcggtgtgggacgaggccgcgcaggagatc
gtctacaaggactacgtgcacctcggcatcgcggcggcgaccccgcgcggtctcgtcgtg
ccgaagatccgggacgcggattccttgtcgctcaaggaactcgcggtcgcgctcaccgag
ctgaccgacgtcgcgcgcgagggcaagacgacgccggcggcgatgctgggcggcacgttc
acgatcaccaacgtcggcgtgttcggcgtcgacaccggcacgccgatcatcaacccgggc
gaatcggcgatcctggccgtcggggcgatccgcgacaccccgtgggtggtcgacggcgag
atcaaggtgcgcaaggtgatgcagctgtcgctgagcttcgaccaccgggtggtcgacgga
cagcaggggtcggagttcctcgccgacgtcggcgcgctgctcgccgatccggcggtcgcg
atcacgtactga
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