Amycolatopsis sp. DSM 110486: K1T34_36170
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Entry
K1T34_36170 CDS
T10626
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
amyd Amycolatopsis sp. DSM 110486
Pathway
amyd00909
Sesquiterpenoid and triterpenoid biosynthesis
amyd01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
amyd00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
K1T34_36170 (shc)
Enzymes [BR:
amyd01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
K1T34_36170 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
K1T34_36170 (shc)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
TED_complement
Motif
Other DBs
NCBI-ProteinID:
QYN18156
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All DBs
Position
complement(7459596..7461518)
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AA seq
640 aa
AA seq
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MTQTVPGTSTSDTPRERSRTPEETLAAGIEFLRGEQDAAGWWKGELSTNVTMDAEDLLLR
QFLGILTEQQKEESARWIRSQQRDDGTWANFPGGPADLSTTVEAWVALRLAGDPAHAPWL
VEAAGWIRAHGGLESTRVFTRIWLAMFGQWSWADLPNLPPELIFLPSWFPLNVYDFACWA
RQTIVPLTIVGTLRPKRKLPFDVAELRVGESPKKSAAPWTWDGVFQNLDTALHTYAKLPF
NPVRKVAMRQAAEWILARQESDGSWGGIQPPWVYSILALHLLGYSLDHPALKAGLEGLED
FTVREETEQGWVRRLEACQSPVWDTALAMTALLDAGVSPGDETLVRATEWMLGEEITVPG
DWMVRRPSLAPGGFAFEFANDGYPDTDDTAEVVLALRRMGRPDHLRIRGAIDRSVKWLEG
MQSSDGGWGAFDADNTQVLATKLPFCDFGAVIDPPSADVTAHVVEMLAAEGKADTTECRR
GVKWLLDNQEADGSWFGRWGANYVYGTGAVVPALVLAGMPASDVRIRRAVRYLTEHQNPN
GGWGEDLRSYDDPGKWSGRGESTPSQTAWALLALLAAGERDSAATTEGVAWLCEQQRADG
GWDEDFHTGTGFPGDFYLSYHLYRVVFPLSALGRYVRSSS
NT seq
1923 nt
NT seq
+upstream
nt +downstream
nt
atgacgcagaccgtccccgggacgtccacttcggacaccccgcgcgaacgctcgcgtact
ccggaagaaaccctcgccgccgggatcgagttcctgcgcggcgagcaggacgcggccggc
tggtggaagggtgagctctccaccaacgtcacgatggacgccgaagacctgctgctgcgc
cagttcctcggcattctcaccgaacagcagaaagaagagtcggcgcgctggatccgatcg
cagcaaagggacgacggcacgtgggccaacttccccggcggcccggccgacttgtcgacc
accgtggaggcgtgggtcgccctgcggctggccggtgacccggcccacgcgccgtggctc
gtcgaggcggccggctggatccgcgcgcacggcggtctggagagcacccgcgtgttcacg
cggatctggctcgcgatgttcgggcagtggtcgtgggccgacctgccgaacctgccaccg
gagctgatcttcctgccgtcgtggtttccgctcaacgtctacgacttcgcgtgctgggca
cgccagaccatcgtgccgctcacgatcgtcggcacgctgcggccgaagcgaaagctgccg
ttcgacgtggccgaactgcgcgtcggtgagagcccgaagaagtccgcggcgccgtggacg
tgggacggggtgttccagaacctcgacaccgcgctgcacacgtatgcgaagctgccgttc
aacccggtgcgcaaggtcgcgatgcgccaggccgccgagtggatcctggcgcgccaggag
tccgacggctcgtggggcggcatccagccgccgtgggtgtactcgatcctcgcgctgcac
ctgctcggctattcgctcgaccaccccgcgctcaaagccggcctcgaaggtctcgaagac
ttcaccgtccgcgaggagaccgaacagggctgggtgcgccggctcgaggcgtgccagtcg
ccggtgtgggataccgcgctcgcgatgaccgcgctgctcgacgcgggcgtctcccccggc
gacgagacgctggtgcgcgcgacggagtggatgctgggcgaggagatcaccgtgccgggc
gactggatggtgcgccgcccgtcgctcgcgccgggcgggttcgcgttcgagttcgccaac
gacggttaccccgacaccgacgacaccgccgaggtggtgctggcgctgcggcgcatgggc
cggcccgaccacctgcgcatccgcggggcgatcgaccgcagcgtgaagtggctcgaaggc
atgcagtccagcgacggcggctggggcgcgttcgacgcggacaacacgcaggtgctcgcc
acgaagctgccgttctgcgacttcggtgccgtgatcgacccgccgtcggcggacgtcacc
gcgcacgtcgtggagatgctggcggccgagggcaaggcggacacgaccgaatgccgccgt
ggcgtgaagtggttgctggacaaccaggaggccgacggttcgtggttcggccggtggggc
gcgaactacgtgtacggcacgggcgcggtcgtgcccgcgctggtcctcgccgggatgccg
gcctcggacgtccggatccgccgcgccgtgcggtacctgaccgagcaccagaaccccaac
ggcggctggggcgaggacctgcgctcctacgacgacccggggaagtggtcgggccgcggc
gagtcgacgccgtcgcagaccgcgtgggcgctgctcgcgctgctggccgccggcgagcgg
gactccgccgcgacgacggagggcgtggcatggctgtgcgagcagcagcgcgcagacggc
ggctgggacgaggacttccacaccggcacgggcttccccggcgatttctacctgtcgtac
cacctctaccgcgtcgtgttcccgctgtcggcgctgggccggtacgtgcggagctcctcg
tga
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