KEGG   Amycolatopsis sp. EV170708-02-1: MJQ72_18240
Entry
MJQ72_18240       CDS       T10873                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
amye  Amycolatopsis sp. EV170708-02-1
Pathway
amye03030  DNA replication
amye03410  Base excision repair
amye03420  Nucleotide excision repair
amye03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:amye00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    MJQ72_18240 (ligA)
   03410 Base excision repair
    MJQ72_18240 (ligA)
   03420 Nucleotide excision repair
    MJQ72_18240 (ligA)
   03430 Mismatch repair
    MJQ72_18240 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:amye03032]
    MJQ72_18240 (ligA)
   03400 DNA repair and recombination proteins [BR:amye03400]
    MJQ72_18240 (ligA)
Enzymes [BR:amye01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     MJQ72_18240 (ligA)
DNA replication proteins [BR:amye03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     MJQ72_18240 (ligA)
DNA repair and recombination proteins [BR:amye03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     MJQ72_18240 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     MJQ72_18240 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     MJQ72_18240 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      MJQ72_18240 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 DNA_ligase_ZBD PTCB-BRCT Nlig-Ia HHH BRCT_2
Other DBs
NCBI-ProteinID: UMP06630
LinkDB
Position
3869246..3871378
AA seq 710 aa
MSSELPENPGPAQDVTDVPADVRERHAELAEEIRGHQFRYYVLDSPIVSDGQFDELLNEL
QAIEDEHPGLVTPESPTQNVGGTFSTEFVAHDHLERMLSLDNVFDTEEFETWVERVQKEI
GATKYLAELKIDGLAINLLYENGRLTRALTRGDGRTGEDVTLNVRTLEQVPERLTGTDEF
PVPALVEVRGEVFFRVEDFLALNAKMVEAGKDPYANPRNTAAGSLRQKDPKITKSRNLRL
ICHGLGKREGFEPKRQSEAYDALAAWGLPVSPHSKVLTSGEELLEHIRYWGEHRHDAEHE
IDGVVIKVDEVALQRRLGTTSRAPRWAIAYKYPPEEAITTLLDIQVNVGRTGRVTPFAVM
EPVKVAGSTVAMATLHNQEEVKRKGVLIGDKVVIRKAGDVIPEVLGPVADARTGEEREFV
MPLRCPNCDTELAYQKEGDIDIRCPNAQFCPAQRRERLFHLASRNVFDIEVVGYEAAVAL
LDAGVVHDEGDIFDLDEEKLLQVELFRTKAGELSANGRKLLENLESVKDRPLWRVIVGLS
IRHVGPTAAQALAREFGSLERIENASEEELAAVDGVGPTIVRAAKEWFEVDWHREIVEKW
RAAGVRMEEERDESVPRNLEGLSIVVTGSLNDYSRDEAKEFIMARGGKAAGSVSKKTAFV
VVGDAPGTKYDKAVQLKVPVLDENGFRVLLEDGPEAAAELALVTEEEPGD
NT seq 2133 nt   +upstreamnt  +downstreamnt
gtgagcagcgaacttcccgagaaccccggtccggcgcaggacgtcacggacgtgcccgcc
gacgtccgcgaaaggcatgccgagctggcggaggagatccgcgggcaccagttccggtac
tacgtgctggattcaccgatcgtgtccgacggccagttcgacgagctgctcaacgaactc
caggccatcgaggacgaacatccggggctggtgacgccggagtcgccgacgcagaacgtc
ggtggcaccttctccaccgagttcgtcgcgcacgaccacctcgagcgcatgctcagcctc
gacaacgtcttcgacaccgaggagttcgagacctgggtcgagcgggtccagaaggagatc
ggcgcgacgaagtacctcgccgaactgaagatcgacgggctcgcgatcaacctgctgtac
gagaacggccgcctcacccgcgcgctgaccaggggcgacggccgcaccggtgaggacgtc
acgctcaacgtccgcacgctggagcaggtgcccgagcggctgaccgggacggacgagttc
cctgtgcccgcgctggtcgaggtccgcggcgaggtgttcttccgcgtcgaggacttcctg
gcgctgaacgcgaagatggtcgaggcgggcaaggatccgtacgcgaacccgcgcaacacg
gccgctggttcgctacggcagaaggatcccaagatcacgaagtcgcgcaatctgcggctg
atctgccacggcctcggcaaacgcgagggtttcgagccgaagcgtcaatccgaggcgtac
gacgcgctcgccgcgtggggcctgccggtctcgccgcacagcaaggtgctgacttccggc
gaggagctgctggagcacatccggtactggggcgagcatcgccacgacgccgagcacgag
atcgacggcgtcgtcatcaaggtcgacgaggtcgcgctgcagcggcgtctaggcacgacg
tcgcgggcgccgcgctgggcgatcgcctacaagtacccgcccgaagaggcgatcaccacg
ctcctggacatccaggtcaacgtcggccgcaccggtcgcgtcaccccgttcgcggtgatg
gagccggtgaaggtggccggatccacggtcgcgatggcgacgctgcacaaccaggaagag
gtcaagcgcaagggtgtgctgatcggggacaaggtcgtcatccgcaaggcgggcgacgtc
atccccgaggtgctcggcccggtggcggacgcgcgcaccggcgaagagcgcgagttcgtc
atgccgctgcgctgccccaactgcgacaccgaactggcgtaccagaaggagggcgacatc
gacatccgttgcccgaacgcgcagttctgccccgcgcagcggcgggagcggctgttccat
ctggcgagccggaacgtcttcgacatcgaggtggtcgggtacgaggccgcggtggcgctg
ctggacgccggtgtcgtgcacgacgagggcgacatcttcgacctggacgaggagaagctg
ctccaggtcgagctgttccgcaccaaggcgggggagctctcggccaacgggcgcaaactg
ctggagaacctggaatcggtcaaggatcgtccactgtggagggtcatcgtcgggctgtcg
atccggcacgtgggcccgacggccgcacaggcgctcgcccgggaattcggttcgctggaa
cggatcgagaacgcctccgaagaggagctcgccgccgtcgacggggtcgggccgaccatc
gtgcgggccgcgaaggaatggttcgaggtcgattggcaccgcgagatcgtcgagaagtgg
cgcgcggcgggcgtgcggatggaggaggagcgcgacgagtccgtcccgcgcaacctcgaa
ggcctgtccatcgtcgtcaccggctcgctgaacgactactcccgagacgaggccaaggag
ttcatcatggcccgcggcgggaaggcggccggttcggtgtcgaagaagacggcgttcgtc
gtcgtcggcgacgcgccgggcacgaagtacgacaaggccgtgcagctgaaagtgccggtg
ctcgacgagaacggcttccgcgtgctcctggaagacgggcccgaggccgcggccgagctg
gcgctggtgaccgaggaggaacccggtgactga

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