Amycolatopsis sp. EV170708-02-1: MJQ72_28280
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Entry
MJQ72_28280 CDS
T10873
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
amye Amycolatopsis sp. EV170708-02-1
Pathway
amye00010
Glycolysis / Gluconeogenesis
amye00020
Citrate cycle (TCA cycle)
amye00620
Pyruvate metabolism
amye00785
Lipoic acid metabolism
amye01100
Metabolic pathways
amye01110
Biosynthesis of secondary metabolites
amye01120
Microbial metabolism in diverse environments
amye01200
Carbon metabolism
amye01210
2-Oxocarboxylic acid metabolism
Module
amye_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amye00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MJQ72_28280 (aceE)
00020 Citrate cycle (TCA cycle)
MJQ72_28280 (aceE)
00620 Pyruvate metabolism
MJQ72_28280 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MJQ72_28280 (aceE)
Enzymes [BR:
amye01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MJQ72_28280 (aceE)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
UMP00376
LinkDB
All DBs
Position
6252003..6254798
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AA seq
931 aa
AA seq
DB search
MAPQNDGASGKETPARVRVIRDGLAAHLPDIDPEETAEWLDSFDEALARGGQQRARYLML
RILERARERHVGVPALTSTDYVNTIPTENEPWFPGDEEIERRYRAYIRWNAAIMVHRAQR
PGVGVGGHISTYGSSAALYEVGFNHFFRGKDHSGGGDQIFIQGHASPGIYARAFLEGRLT
ENQLDGFRQEFSHAGEGGGLPSYPHPRLMPEFWENPTVSMGLGPMNAIYQARFNRYLRDR
GIKDTSDQHVWAFLGDGEMDEPESRGLIHVAASEGLDNLTFVINCNLQRLDGPVRGNGKI
IQELESYFRGAGWNVIKVIWGREWDSLLHADRDGALVNLMNTTPDGDFQTYKANDGAFVR
EHFFGRDPRTKELVKDLTDADVWNLKRGGHDYRKVYAAYKSSLEHHGQPTVILAHTIKGY
GLGPSFEGRNATHQMKKLTLDDLKLFRDAQRIPISDEELERDPKLPPYYHPGKESPEIEY
MLGRRKALGGFLPERRPKASKALVLPGDKVYEGIRKGSGKQEVATTMAFVRLVRELAKDS
EIGKRIVPIIPDEARTFGLDSMFPTAKIYNPHGQTYTSVDASLMLAYKESEKGVILHEGI
NEAGSTASFTAVGTSYATHGEPMIPIYIFYSMFGFQRTGDGLYAAADQMARGFVLGATAG
RTTLTGEGLQHADGHSLLLAATNPAVVAYDAAWSFEIAHIVRDGLRRMYGETGPDGNGEN
IFYYMTIYNEPYQQPAEPENLDVDGLLKGLYKYADAPSGDGPEAQILVSGVTMPDALRAQ
RMLAEEWGVRAAVWSATSWTELRREAVEADHDNLLHPGDTPRVPYVTQKLSGANGPVVAV
SDWMRAVPDLIRPWVPNDMLTLGTDGFGFSDTRPAARRKFLVDAQSIVVGTLSALAKRGE
IDQSKAAEAARKYRLDDVAAAGPQLSDSGSA
NT seq
2796 nt
NT seq
+upstream
nt +downstream
nt
ttggccccgcagaacgacggcgcctccggcaaggagaccccggcacgcgtccgcgtcatc
cgtgacggattggcggcgcacctgcccgacatcgacccggaggagaccgccgaatggctg
gactccttcgacgaggcgctggccaggggtggtcagcagcgcgcccggtacctgatgctg
cgcatcctcgagcgggccagggagcgccacgtcggcgtcccggcgctgacgtcgacggac
tacgtcaacaccatccccaccgagaacgaaccctggttccccggtgacgaggagatcgag
cgccggtatcgcgcctacatccggtggaacgccgcgatcatggtgcaccgcgcgcagcgt
cccggcgtcggcgtcggcgggcacatctcgacctacggctcgtccgcggcgctgtacgaa
gtgggcttcaaccacttcttccgcggcaaggaccactcgggcggcggcgaccagatcttc
atccagggccacgcctcccccggcatctacgcccgcgcgttcctcgagggcaggctgacc
gagaaccagctggacggcttccgccaggagttctcgcacgccggcgagggcggcggcctg
ccgtcgtacccgcacccgcggctgatgccggagttctgggagaacccgaccgtgtccatg
ggcctcggcccgatgaacgcgatctaccaggcgcgcttcaaccgctacctgcgcgatcgc
ggcatcaaggacaccagcgaccagcacgtctgggcgttcctcggcgacggcgagatggac
gagccggaatcgcgcggcctcatccacgtggccgcgagcgaaggcctcgacaacctgacc
ttcgtgatcaactgcaacctgcagcggctcgacggcccggtgcgcggcaacggcaagatc
atccaggagctggagtcgtacttccgcggcgccggctggaacgtcatcaaggtcatctgg
ggccgcgagtgggactcgctgctgcacgcggaccgcgacggcgcgctggtcaacctgatg
aacaccacgccggacggcgatttccagacctacaaggccaacgacggcgccttcgtccgc
gagcacttcttcggccgcgacccgcggaccaaggaactggtcaaggacctcaccgacgcc
gacgtctggaacctcaagcgcggcgggcacgactaccgcaaggtctacgcggcctacaag
tcgtcgctggagcaccacggccagccgacggtcatcctggcccacaccatcaagggttac
ggcctcggaccgtccttcgagggccgcaacgccacgcaccagatgaagaagctcaccctc
gacgacctcaagctgttccgggacgcccagcgcatcccgatcagcgacgaggagctcgag
cgcgacccgaagctgccgccgtactaccaccccggcaaggaatcgccggagatcgagtac
atgctcggccgccgcaaggcgctgggcgggttcctgccggagcgccgcccgaaggcctcg
aaggccctcgtgctgcccggcgacaaggtctacgaaggcatccgcaagggctcgggcaag
caggaggtcgccaccacgatggcgttcgtccggctcgtccgcgagctggcgaaggactcc
gagatcggcaagcggatcgtcccgatcatcccggacgaggcgcgcaccttcggcctcgac
tcgatgttcccgacggccaagatctacaacccgcacggccagacgtacacgtcggtcgac
gcgagcctgatgctggcctacaaggagtccgaaaagggcgtcatcctgcacgagggcatc
aacgaggccggctcgaccgcgtcgttcaccgccgtcggcacctcgtacgccacgcacggc
gagccgatgatcccgatctacatcttctactcgatgttcgggttccagcggaccggtgac
ggcctctacgcggcggcggaccagatggcccgcgggttcgtgctcggcgccaccgccggc
cgcaccacgctgaccggtgaaggcctgcagcacgccgacgggcactcgctgctgctggcg
gcgaccaacccggccgtcgtggcctacgacgcggcgtggtcgttcgagatcgcccacatc
gtgcgggacggccttcgccggatgtacggcgagaccgggccggacggcaacggcgagaac
atcttctactacatgacgatctacaacgagccctaccagcagcccgccgagcccgagaac
ctcgacgtcgacggcctgctcaagggtctctacaagtacgcggacgccccgtcgggcgac
ggcccggaggcgcagatcctggtctccggcgtcaccatgccggacgcgctgcgtgcccag
cggatgctggccgaggagtggggcgtacgcgcggccgtgtggtcggcgacgtcgtggacc
gagctgcggcgcgaggccgtcgaggccgaccacgacaacctgctccacccgggcgacacc
ccgcgtgtgccgtacgtcacgcagaagctgtccggcgcgaacggaccggtcgtcgcggtc
tcggactggatgcgggccgtgccggacctcatccgcccgtgggtgccgaacgacatgctg
acgctgggcaccgacgggttcggattctccgacacccgtcccgccgcccggcggaagttc
ctggtcgacgcccagtcgatcgtggtcggcacgctgagcgcgctcgccaagcgcggcgag
atcgaccagtcgaaggcggcggaggcggcgcgcaagtaccgtctcgacgacgtcgccgcc
gcgggtccgcagttgtcggactccggtagcgcctga
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