KEGG   Aotus nancymaae (Ma's night monkey): 105705018
Entry
105705018         CDS       T10127                                 
Symbol
PIK3R3
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
anan  Aotus nancymaae (Ma's night monkey)
Pathway
anan01521  EGFR tyrosine kinase inhibitor resistance
anan01522  Endocrine resistance
anan01524  Platinum drug resistance
anan04012  ErbB signaling pathway
anan04014  Ras signaling pathway
anan04015  Rap1 signaling pathway
anan04024  cAMP signaling pathway
anan04062  Chemokine signaling pathway
anan04066  HIF-1 signaling pathway
anan04068  FoxO signaling pathway
anan04070  Phosphatidylinositol signaling system
anan04071  Sphingolipid signaling pathway
anan04072  Phospholipase D signaling pathway
anan04081  Hormone signaling
anan04140  Autophagy - animal
anan04145  Phagocytosis
anan04150  mTOR signaling pathway
anan04151  PI3K-Akt signaling pathway
anan04152  AMPK signaling pathway
anan04210  Apoptosis
anan04211  Longevity regulating pathway
anan04213  Longevity regulating pathway - multiple species
anan04218  Cellular senescence
anan04360  Axon guidance
anan04370  VEGF signaling pathway
anan04380  Osteoclast differentiation
anan04510  Focal adhesion
anan04517  IgSF CAM signaling
anan04518  Integrin signaling
anan04550  Signaling pathways regulating pluripotency of stem cells
anan04611  Platelet activation
anan04613  Neutrophil extracellular trap formation
anan04620  Toll-like receptor signaling pathway
anan04625  C-type lectin receptor signaling pathway
anan04630  JAK-STAT signaling pathway
anan04650  Natural killer cell mediated cytotoxicity
anan04660  T cell receptor signaling pathway
anan04662  B cell receptor signaling pathway
anan04664  Fc epsilon RI signaling pathway
anan04666  Fc gamma R-mediated phagosome formation
anan04668  TNF signaling pathway
anan04670  Leukocyte transendothelial migration
anan04722  Neurotrophin signaling pathway
anan04725  Cholinergic synapse
anan04750  Inflammatory mediator regulation of TRP channels
anan04810  Regulation of actin cytoskeleton
anan04910  Insulin signaling pathway
anan04914  Progesterone-mediated oocyte maturation
anan04915  Estrogen signaling pathway
anan04917  Prolactin signaling pathway
anan04919  Thyroid hormone signaling pathway
anan04923  Regulation of lipolysis in adipocytes
anan04926  Relaxin signaling pathway
anan04929  GnRH secretion
anan04930  Type II diabetes mellitus
anan04931  Insulin resistance
anan04932  Non-alcoholic fatty liver disease
anan04933  AGE-RAGE signaling pathway in diabetic complications
anan04935  Growth hormone synthesis, secretion and action
anan04960  Aldosterone-regulated sodium reabsorption
anan04973  Carbohydrate digestion and absorption
anan05010  Alzheimer disease
anan05017  Spinocerebellar ataxia
anan05020  Prion disease
anan05100  Bacterial invasion of epithelial cells
anan05135  Yersinia infection
anan05142  Chagas disease
anan05146  Amoebiasis
anan05160  Hepatitis C
anan05161  Hepatitis B
anan05162  Measles
anan05163  Human cytomegalovirus infection
anan05164  Influenza A
anan05165  Human papillomavirus infection
anan05166  Human T-cell leukemia virus 1 infection
anan05167  Kaposi sarcoma-associated herpesvirus infection
anan05168  Herpes simplex virus 1 infection
anan05169  Epstein-Barr virus infection
anan05170  Human immunodeficiency virus 1 infection
anan05171  Coronavirus disease
anan05200  Pathways in cancer
anan05203  Viral carcinogenesis
anan05205  Proteoglycans in cancer
anan05206  MicroRNAs in cancer
anan05207  Chemical carcinogenesis - receptor activation
anan05208  Chemical carcinogenesis - reactive oxygen species
anan05210  Colorectal cancer
anan05211  Renal cell carcinoma
anan05212  Pancreatic cancer
anan05213  Endometrial cancer
anan05214  Glioma
anan05215  Prostate cancer
anan05218  Melanoma
anan05220  Chronic myeloid leukemia
anan05221  Acute myeloid leukemia
anan05222  Small cell lung cancer
anan05223  Non-small cell lung cancer
anan05224  Breast cancer
anan05225  Hepatocellular carcinoma
anan05226  Gastric cancer
anan05230  Central carbon metabolism in cancer
anan05231  Choline metabolism in cancer
anan05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
anan05415  Diabetic cardiomyopathy
anan05417  Lipid and atherosclerosis
anan05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:anan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    105705018 (PIK3R3)
   04014 Ras signaling pathway
    105705018 (PIK3R3)
   04015 Rap1 signaling pathway
    105705018 (PIK3R3)
   04370 VEGF signaling pathway
    105705018 (PIK3R3)
   04630 JAK-STAT signaling pathway
    105705018 (PIK3R3)
   04668 TNF signaling pathway
    105705018 (PIK3R3)
   04066 HIF-1 signaling pathway
    105705018 (PIK3R3)
   04068 FoxO signaling pathway
    105705018 (PIK3R3)
   04070 Phosphatidylinositol signaling system
    105705018 (PIK3R3)
   04072 Phospholipase D signaling pathway
    105705018 (PIK3R3)
   04071 Sphingolipid signaling pathway
    105705018 (PIK3R3)
   04024 cAMP signaling pathway
    105705018 (PIK3R3)
   04151 PI3K-Akt signaling pathway
    105705018 (PIK3R3)
   04152 AMPK signaling pathway
    105705018 (PIK3R3)
   04150 mTOR signaling pathway
    105705018 (PIK3R3)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    105705018 (PIK3R3)
   04517 IgSF CAM signaling
    105705018 (PIK3R3)
   04518 Integrin signaling
    105705018 (PIK3R3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    105705018 (PIK3R3)
   04140 Autophagy - animal
    105705018 (PIK3R3)
  09143 Cell growth and death
   04210 Apoptosis
    105705018 (PIK3R3)
   04218 Cellular senescence
    105705018 (PIK3R3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105705018 (PIK3R3)
   04550 Signaling pathways regulating pluripotency of stem cells
    105705018 (PIK3R3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105705018 (PIK3R3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105705018 (PIK3R3)
   04613 Neutrophil extracellular trap formation
    105705018 (PIK3R3)
   04620 Toll-like receptor signaling pathway
    105705018 (PIK3R3)
   04625 C-type lectin receptor signaling pathway
    105705018 (PIK3R3)
   04650 Natural killer cell mediated cytotoxicity
    105705018 (PIK3R3)
   04660 T cell receptor signaling pathway
    105705018 (PIK3R3)
   04662 B cell receptor signaling pathway
    105705018 (PIK3R3)
   04664 Fc epsilon RI signaling pathway
    105705018 (PIK3R3)
   04666 Fc gamma R-mediated phagosome formation
    105705018 (PIK3R3)
   04670 Leukocyte transendothelial migration
    105705018 (PIK3R3)
   04062 Chemokine signaling pathway
    105705018 (PIK3R3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105705018 (PIK3R3)
   04923 Regulation of lipolysis in adipocytes
    105705018 (PIK3R3)
   04929 GnRH secretion
    105705018 (PIK3R3)
   04915 Estrogen signaling pathway
    105705018 (PIK3R3)
   04914 Progesterone-mediated oocyte maturation
    105705018 (PIK3R3)
   04917 Prolactin signaling pathway
    105705018 (PIK3R3)
   04926 Relaxin signaling pathway
    105705018 (PIK3R3)
   04935 Growth hormone synthesis, secretion and action
    105705018 (PIK3R3)
   04919 Thyroid hormone signaling pathway
    105705018 (PIK3R3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    105705018 (PIK3R3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    105705018 (PIK3R3)
  09156 Nervous system
   04725 Cholinergic synapse
    105705018 (PIK3R3)
   04722 Neurotrophin signaling pathway
    105705018 (PIK3R3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105705018 (PIK3R3)
  09158 Development and regeneration
   04360 Axon guidance
    105705018 (PIK3R3)
   04380 Osteoclast differentiation
    105705018 (PIK3R3)
  09149 Aging
   04211 Longevity regulating pathway
    105705018 (PIK3R3)
   04213 Longevity regulating pathway - multiple species
    105705018 (PIK3R3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105705018 (PIK3R3)
   05206 MicroRNAs in cancer
    105705018 (PIK3R3)
   05205 Proteoglycans in cancer
    105705018 (PIK3R3)
   05207 Chemical carcinogenesis - receptor activation
    105705018 (PIK3R3)
   05208 Chemical carcinogenesis - reactive oxygen species
    105705018 (PIK3R3)
   05203 Viral carcinogenesis
    105705018 (PIK3R3)
   05230 Central carbon metabolism in cancer
    105705018 (PIK3R3)
   05231 Choline metabolism in cancer
    105705018 (PIK3R3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105705018 (PIK3R3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105705018 (PIK3R3)
   05212 Pancreatic cancer
    105705018 (PIK3R3)
   05225 Hepatocellular carcinoma
    105705018 (PIK3R3)
   05226 Gastric cancer
    105705018 (PIK3R3)
   05214 Glioma
    105705018 (PIK3R3)
   05221 Acute myeloid leukemia
    105705018 (PIK3R3)
   05220 Chronic myeloid leukemia
    105705018 (PIK3R3)
   05218 Melanoma
    105705018 (PIK3R3)
   05211 Renal cell carcinoma
    105705018 (PIK3R3)
   05215 Prostate cancer
    105705018 (PIK3R3)
   05213 Endometrial cancer
    105705018 (PIK3R3)
   05224 Breast cancer
    105705018 (PIK3R3)
   05222 Small cell lung cancer
    105705018 (PIK3R3)
   05223 Non-small cell lung cancer
    105705018 (PIK3R3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105705018 (PIK3R3)
   05170 Human immunodeficiency virus 1 infection
    105705018 (PIK3R3)
   05161 Hepatitis B
    105705018 (PIK3R3)
   05160 Hepatitis C
    105705018 (PIK3R3)
   05171 Coronavirus disease
    105705018 (PIK3R3)
   05164 Influenza A
    105705018 (PIK3R3)
   05162 Measles
    105705018 (PIK3R3)
   05168 Herpes simplex virus 1 infection
    105705018 (PIK3R3)
   05163 Human cytomegalovirus infection
    105705018 (PIK3R3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105705018 (PIK3R3)
   05169 Epstein-Barr virus infection
    105705018 (PIK3R3)
   05165 Human papillomavirus infection
    105705018 (PIK3R3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    105705018 (PIK3R3)
   05100 Bacterial invasion of epithelial cells
    105705018 (PIK3R3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    105705018 (PIK3R3)
   05142 Chagas disease
    105705018 (PIK3R3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105705018 (PIK3R3)
   05017 Spinocerebellar ataxia
    105705018 (PIK3R3)
   05020 Prion disease
    105705018 (PIK3R3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105705018 (PIK3R3)
   05418 Fluid shear stress and atherosclerosis
    105705018 (PIK3R3)
   05415 Diabetic cardiomyopathy
    105705018 (PIK3R3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105705018 (PIK3R3)
   04932 Non-alcoholic fatty liver disease
    105705018 (PIK3R3)
   04931 Insulin resistance
    105705018 (PIK3R3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105705018 (PIK3R3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105705018 (PIK3R3)
   01524 Platinum drug resistance
    105705018 (PIK3R3)
   01522 Endocrine resistance
    105705018 (PIK3R3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:anan04131]
    105705018 (PIK3R3)
Membrane trafficking [BR:anan04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    105705018 (PIK3R3)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 SH2_1 DicA_C ODF2_C Transcrip_act Exonuc_VII_L
Other DBs
NCBI-GeneID: 105705018
NCBI-ProteinID: XP_012289983
Ensembl: ENSANAG00000037471
UniProt: A0A2K5F486
LinkDB
Position
Unknown
AA seq 461 aa
MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVTNGMKDCSVSL
QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKP
DLIQLRKIRDQHLVWLNHKGVRQKRLNAWLGIKNEDADENYFINEEDENLPHYDEKTWFV
EDINRVQAEDLLYGKPDGSFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPIHAQMPSLCR
NT seq 1386 nt   +upstreamnt  +downstreamnt
atgtacaatacggtgtggagtatggaccgcgatgacgcagactggagggaggtgatgatg
ccctattcgacagaactgatattttatattgaaatggatcctccagctcttccaccaaaa
ccacctaagccaatgacttcagcagttacaaatggaatgaaggactgttctgtttctctt
caggatgcagaatggtattggggggatatttcaagggaggaggtaaatgacaaattgcgg
gatatgccagatgggaccttcttggtccgagatgcctcaacaaaaatgcagggagattat
actttgactttgcggaagggaggcaataataaattaataaagatctatcaccgggatggt
aaatatggcttttctgatcctctgacatttaattctgtggtggagctcattaaccactat
caccatgaatctcttgctcagtacaatcccaaacttgatgtgaagctgatgtacccagtg
tcccgataccaacaggatcagttggtaaaagaagataatattgatgcagtaggtaaaaaa
ctgcaagaataccactctcagtatcaggagaagagtaaagagtatgataggctatatgaa
gaatatactagaacatcccaggaaatacagatgaagaggactgcaatagaagcttttaat
gaaacaattaaaatatttgaagagcagtgtcacacacaagaacaacacagcaaagaatat
attgagcgatttcgcagagaggggaatgaaaaggagattgaacgaattatgatgaattat
gataaattgaaatcacgtctgggcgagattcatgatagcaaaatgcgtctagagcaggat
ttgaagaaacaagctttggacaaccgagaaatagataaaaaaatgaatagtatcaaacct
gacctgatccagctgcgaaagatccgagatcaacaccttgtatggctcaatcacaaagga
gtgagacagaaacgcctgaatgcctggctgggaattaagaatgaggatgctgatgagaac
tattttattaatgaggaagatgaaaacctgccccactatgatgagaaaacctggtttgtt
gaggatatcaatcgagtacaagcagaggatttgctttatgggaaacctgatggttcattc
ttaattcgtgagagtagcaagaaaggatgctatgcttgctctgtggtggccgatggggaa
gtgaagcactgtgtgatctacagcactgctcggggctatggctttgctgagccctacaac
ctgtacagctctctgaaggagctggtgctccattaccagcagacatccttggttcagcac
aacgactccctcaacgtcaggcttgcctaccctattcatgcacagatgccctcgctctgc
agataa

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