Aotus nancymaae (Ma's night monkey): 105705813 Help Entry 105705813         CDS       T10127                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism anan  Aotus nancymaae (Ma's night monkey) Pathway anan04010   MAPK signaling pathway anan04014   Ras signaling pathway anan04015   Rap1 signaling pathway anan04022   cGMP-PKG signaling pathway anan04066   HIF-1 signaling pathway anan04068   FoxO signaling pathway anan04072   Phospholipase D signaling pathway anan04081   Hormone signaling anan04150   mTOR signaling pathway anan04151   PI3K-Akt signaling pathway anan04152   AMPK signaling pathway anan04211   Longevity regulating pathway anan04213   Longevity regulating pathway - multiple species anan04520   Adherens junction anan04910   Insulin signaling pathway anan04913   Ovarian steroidogenesis anan04923   Regulation of lipolysis in adipocytes anan04930   Type II diabetes mellitus anan04931   Insulin resistance anan04932   Non-alcoholic fatty liver disease anan04960   Aldosterone-regulated sodium reabsorption anan05010   Alzheimer disease anan05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:anan00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105705813 (INSR)    04014 Ras signaling pathway     105705813 (INSR)    04015 Rap1 signaling pathway     105705813 (INSR)    04066 HIF-1 signaling pathway     105705813 (INSR)    04068 FoxO signaling pathway     105705813 (INSR)    04072 Phospholipase D signaling pathway     105705813 (INSR)    04022 cGMP-PKG signaling pathway     105705813 (INSR)    04151 PI3K-Akt signaling pathway     105705813 (INSR)    04152 AMPK signaling pathway     105705813 (INSR)    04150 mTOR signaling pathway     105705813 (INSR)   09133 Signaling molecules and interaction    04081 Hormone signaling     105705813 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     105705813 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105705813 (INSR)    04923 Regulation of lipolysis in adipocytes     105705813 (INSR)    04913 Ovarian steroidogenesis     105705813 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     105705813 (INSR)   09149 Aging    04211 Longevity regulating pathway     105705813 (INSR)    04213 Longevity regulating pathway - multiple species     105705813 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     105705813 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     105705813 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     105705813 (INSR)    04932 Non-alcoholic fatty liver disease     105705813 (INSR)    04931 Insulin resistance     105705813 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:anan01001]     105705813 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:anan04090]     105705813 (INSR) Enzymes [BR:anan01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      105705813 (INSR) Protein kinases [BR:anan01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    105705813 (INSR) CD molecules [BR:anan04090]  Proteins   105705813 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  105705813 NCBI-ProteinID:  XP_064238069 Ensembl:  ENSANAG00000021860 LinkDB All DBs Position Unknown AA seq 1382 aa AA seqDB search MGAGSHRGAAAAPLLVAVAALFLGAAGQMYPGEVCPGMDIRNNLSRLHELENCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTSKGKTSCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPGDPTKCVACRNYYLDGRCVDSCPPPYYQFQDWRCVNFSFCQDLHYKCKNSRRQS CYQYVIHNNKCLPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEREKIIDSVTSAQDLRGC TVVNGSLIINIRGGNNLAVELEANLGLIEEISGYLKIRRSYALVSLAFFRKLRLIRGETL EAGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE KNDIALKTNGDQASCENELIKFSSIRTSSDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPQRSSDPTSQSHPGWLMRNLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTAATNPSVPLDPISVSNSSSQIILKWKPPTDPNGNITHYLVFWQ RQVEDSELFELDYCLKGLKLPSRTWSPPVESEGFQKQNQSEEEDLAGECCSCPKTDSQIQ KELEESSFRKTFEDYLHNVVFIPRRTSPGPGAENSRPTRKRRSLDDIGNMTEAEPTVAAL PNTSSTMESMSPEEPKPFEKVVNRESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYV SARTMPEAKADDIVSPVTHEILENNIVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV SRKHFTLERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVSDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYIFLRKRQQDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNAKDVIKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGIFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMEGGYLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVSLLKDDLHPSFPEVSFFHSEENKAPESEELEVE FEDMENVPLDRSSHCQREEAGGRDGGSSLGLKRSYEEHIPYTHMNGGKKNGRILALPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggagccaccggggggcggcggccgcgccgctgctggtggcggtggctgcg ctgttcttgggcgccgcgggccaaatgtaccccggagaggtgtgccctggcatggatatc cggaacaacctcagcaggctgcatgagctggagaattgctctgtcatcgaaggacactta cagatactcctgatgttcaaaacgaggcccgaagatttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtctatgggctcgagagcctgaaa gacctgttccccaacctcaccgtcatccggggatcgagactgttcttcaactatgcgctg gtcatcttcgagatggttcacctcaaggaactcggcctctacagcctgatgaacatcacc cggggttctgtccgcattgagaagaacaatgagctctgctacttggccactattgactgg tcccgtatcctggattccgtggaggacaattacatcgtgttgaacaaagatgacaacgag gagtgtggagacatctgtccaggtacctcgaagggcaagaccagctgccctgccaccgtc atcaacgggcagtttgtcgaacggtgttggactcacagtcactgtcagaaagtttgcccg accatctgtaagtcacacggctgcaccgcagaaggcctctgttgccatagtgagtgcttg ggcaactgttctgagcccggtgaccccaccaagtgcgtggcctgccgcaactactacctg gacggcaggtgtgtggactcctgcccgcccccatactaccagttccaggactggcgctgc gtgaacttcagcttctgccaggacctgcactacaaatgcaagaattcgcggaggcagagc tgctaccagtacgtcattcacaacaacaagtgcctccccgagtgtccctctgggtacacg atgaattccagcaacttgatgtgcaccccgtgcctgggtccctgtcccaaggtgtgccac cttctagaacgcgagaaaatcatcgactcagtgacgtctgcccaggatctccgaggatgc accgttgtcaatgggagtctgatcatcaacattcgaggaggcaacaatctggcagttgag ctagaagccaacctcggcctcattgaagaaatttcagggtatctaaaaatccgccgatcc tacgctctggtatcacttgccttctttcggaagttgcgtctgattcgaggagagaccttg gaagccgggaactactccttctatgccttggacaaccagaacctaaggcagctctgggac tggagcaaacacaaccttaccatcactcaggggaaactcttcttccactataaccccaaa ctctgcttgtcagaaatccacaagatggaagaagtttcaggaaccaaggggcgccaggag aagaatgacattgccttaaagaccaatggggaccaagcatcctgtgaaaatgaattaatt aaattttcttccattcggacaagttctgacaagatcttgctgaaatgggagccgtactgg ccccctgacttccgagatctcttggggttcatgctgttctacaaagaggccccttatcag aatgtgacggagttcgatgggcaggatgcttgtggttccaacagttggacggtggtagac attgacccgccccagaggtccagtgaccccacatcacagagccacccaggatggctgatg cggaatctcaagccctggacccagtatgctatctttgtgaagaccctggtcaccttttcc gatgaacgccggacctatggggccaagagtgacatcatttatgtccagacagctgccacc aacccgtccgtgccactggatccaatctcagtgtctaactcatcatcccagattattttg aagtggaaaccccccacagaccccaacggcaatatcacccactacctggttttctggcag aggcaggtggaagacagtgagctcttcgagttggattattgcctcaaagggttgaagctg ccctcgaggacctggtctccaccagttgagtctgaaggttttcagaagcagaaccagagt gaagaggaggatttggccggcgagtgttgctcctgtccaaagacagactctcagatccag aaggagctggaggagtcctcgtttaggaagacgtttgaggattacctgcacaatgtggtt ttcatccccagaagaacctctccaggccctggtgcggagaactctaggccgactcgaaaa cgcaggtcccttgacgacattgggaacatgacggaggccgagcccacggtggcagctctc cccaacacttcctcgaccatggagtccatgagtccggaggagcccaagcccttcgagaag gtggtgaacagagagtcgctggtcatctctggcttgcgacacttcacgggctatcgcatc gagctgcaggcttgcaaccaagacacccccgaggaacggtgcagcgtggcagcctatgtc agcgccaggaccatgcctgaagccaaggctgatgacattgtcagccctgtgacccatgaa atccttgagaacaacatcgtccacttgatgtggcaggagccaaaggagcccaatggtctg atcgtgctgtatgaagtgagttatcggcgatacggcgatgaggagctgcatctctgcgtc tcccgcaagcacttcactctggaacggggctgcaggctgcgcgggctgtcaccggggaac tacagcgtgcgagtccgggccacttccctagcgggcaacggctcctggacggaacccacc tatttctacgtgtcagactacttagatgtcccatcaaatattgcaaaaattatcatcggc cccctcatctttgtctttctcttcagtgttgtgattggaagtatttatatattcctgaga aagagacagcaagatggaccgctgggcccactttatgcttcttcaaaccctgagtatctc agtgccagtgatgtgtttccatgctctgtgtacgtgccggacgagtgggaggtgcctcga gagaagatcaccctccttcgtgagctggggcagggctccttcggcatggtgtatgagggc aacgccaaggacgtcatcaagggtgaggcagagacccgcgtggcggtgaagacggtcaac gagtcagccagcctccgagagcggattgagttcctcaatgaggcctcggtcatgaagggc ttcacctgccatcatgtggtgcgcctcctgggagtggtgtccaagggccagcccacgctg gtggtgatggagctgatggctcacggggacctgaagagctacctccgttctctgcggcca gaagctgagaacaatcccggccgccctccccccaccctgcaagagatgattcagatggca gcagagattgctgacgggatggcttacctgaacgccaagaagtttgtgcatcgggacctg gcagccagaaactgcatggtcgctcatgatttcactgtcaaaattggagactttggaatg accagagacatctatgaaacggattactaccggaaagggggcaagggtctgctccctgtg cggtggatggcgccagagtccctgaaggacgggatctttaccacttcttccgacatgtgg tcctttggcgtggtcctttgggaaatcaccagcttggccgaacagccttaccaaggcctg tctaatgaacaagtgttgaaattcgtcatggaaggagggtatctggatcaacctgacaac tgtccagagagagtgaccgatctcatgcgtatgtgctggcaattcaaccccaagatgagg ccaaccttcctggagattgtcagcttgctcaaggatgacttgcaccctagctttccggag gtgtccttctttcacagtgaggagaacaaggctcccgagagtgaggagctggaggtggag tttgaggatatggagaacgtgcccctggatcgttcctcccactgtcagagggaggaggcc gggggccgggatggagggtcctcgctgggtctcaagcggagctacgaagaacacatcccc tacacccacatgaacggaggcaagaagaacgggcggattctggccttgcctcggtccaat ccttcctaa

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