Aotus nancymaae (Ma's night monkey): 105712654 Help Entry 105712654         CDS       T10127                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism anan  Aotus nancymaae (Ma's night monkey) Pathway anan01524   Platinum drug resistance anan04115   p53 signaling pathway anan04210   Apoptosis anan04215   Apoptosis - multiple species anan04217   Necroptosis anan04620   Toll-like receptor signaling pathway anan04621   NOD-like receptor signaling pathway anan04622   RIG-I-like receptor signaling pathway anan04623   Cytosolic DNA-sensing pathway anan04625   C-type lectin receptor signaling pathway anan04657   IL-17 signaling pathway anan04668   TNF signaling pathway anan04932   Non-alcoholic fatty liver disease anan04936   Alcoholic liver disease anan05010   Alzheimer disease anan05016   Huntington disease anan05022   Pathways of neurodegeneration - multiple diseases anan05132   Salmonella infection anan05134   Legionellosis anan05142   Chagas disease anan05145   Toxoplasmosis anan05152   Tuberculosis anan05160   Hepatitis C anan05161   Hepatitis B anan05162   Measles anan05163   Human cytomegalovirus infection anan05164   Influenza A anan05165   Human papillomavirus infection anan05167   Kaposi sarcoma-associated herpesvirus infection anan05168   Herpes simplex virus 1 infection anan05169   Epstein-Barr virus infection anan05170   Human immunodeficiency virus 1 infection anan05200   Pathways in cancer anan05203   Viral carcinogenesis anan05416   Viral myocarditis anan05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:anan00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     105712654 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     105712654 (CASP8)    04215 Apoptosis - multiple species     105712654 (CASP8)    04217 Necroptosis     105712654 (CASP8)    04115 p53 signaling pathway     105712654 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     105712654 (CASP8)    04621 NOD-like receptor signaling pathway     105712654 (CASP8)    04622 RIG-I-like receptor signaling pathway     105712654 (CASP8)    04623 Cytosolic DNA-sensing pathway     105712654 (CASP8)    04625 C-type lectin receptor signaling pathway     105712654 (CASP8)    04657 IL-17 signaling pathway     105712654 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105712654 (CASP8)    05203 Viral carcinogenesis     105712654 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     105712654 (CASP8)    05161 Hepatitis B     105712654 (CASP8)    05160 Hepatitis C     105712654 (CASP8)    05164 Influenza A     105712654 (CASP8)    05162 Measles     105712654 (CASP8)    05168 Herpes simplex virus 1 infection     105712654 (CASP8)    05163 Human cytomegalovirus infection     105712654 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     105712654 (CASP8)    05169 Epstein-Barr virus infection     105712654 (CASP8)    05165 Human papillomavirus infection     105712654 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     105712654 (CASP8)    05134 Legionellosis     105712654 (CASP8)    05152 Tuberculosis     105712654 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105712654 (CASP8)    05142 Chagas disease     105712654 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     105712654 (CASP8)    05016 Huntington disease     105712654 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     105712654 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105712654 (CASP8)    05416 Viral myocarditis     105712654 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     105712654 (CASP8)    04932 Non-alcoholic fatty liver disease     105712654 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     105712654 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:anan01002]     105712654 (CASP8) Enzymes [BR:anan01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      105712654 (CASP8) Peptidases and inhibitors [BR:anan01002]  Cysteine peptidases   Family C14: caspase family    105712654 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN ARM_TT21_5th Motif Other DBs NCBI-GeneID:  105712654 NCBI-ProteinID:  XP_064229257 LinkDB All DBs Position Unknown AA seq 496 aa AA seqDB search MVPGKGGADYIFLPFEKMAFSKMLFDIGEELGSEELAALKFLSLDYIPQRKQEPIKDALM LFQRLQEKRMLEESNLSFLKELLFRINRLDLLNKYLDTSKEEMERELQTPGSAQISAYRV MLYQISEDVSRSELRSFKFLLNKEISKCKLDDDMNLLDIFIEMEKRVILGEEKLDVLKRV CDQINKSLLKIINDYEEFSRERRMSLERSSDESSNGEELFGVMAISDSPREQDSESQASD KVYQMKNKPRGYCLIINNHDFRKAREEVPKLHSIKDRNGTHLDAEALSKTFEELHFEIRP YNDCTGEKIYEILQSYQRMDHSNKDCFICCILSHGDKGVIYGTDGHEAPIYELTSQFTGL KCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGM ATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILAILTEVNYEVSNKDDKKNMGKQM PQPTFTLRKKLVFSSD NT seq 1491 nt NT seq  +upstreamnt  +downstreamnt atggtgcccggaaagggtggagcggattacatcttcctaccttttgaaaagatggccttc agcaaaatgctttttgatattggagaagaactgggaagtgaagaactggctgccctcaag ttcctgagcctggactacatcccacaaaggaagcaagaacccatcaaggatgccttgatg ttattccagagactccaggaaaagagaatgttggaggaaagtaatctgtccttcctgaag gagctgctcttccgaattaatagattggatttgctgaataaatatctagacactagcaag gaggagatggaaagggaacttcagacaccgggcagtgctcagatttctgcctacagggtc atgctctatcagatttcagaagatgtgagcagatcagaattgaggtcttttaagtttctt ttgaataaggagatctccaaatgcaaactggatgatgacatgaacctgctggatattttc atagagatggagaagagggtcatcctgggagaagaaaagttggatgtcctgaaaagagtc tgtgaccaaatcaacaagagcctgctgaagataatcaatgactatgaagaattcagcaga gagagaagaatgagccttgaaagaagttcagatgaatcttcaaatggggaagagttgttt ggggtaatggcaatctcggactctccaagagaacaggacagtgaatcacaggcttcggac aaagtttaccaaatgaaaaataaacctcggggatattgtctgatcatcaacaatcatgat tttcgcaaagcacgggaggaagtgcccaaactccacagcattaaggataggaatggaaca cacctggatgcagaggctttgagcaagacctttgaagagcttcattttgagatcaggccc tacaatgactgcacaggagagaaaatctatgagattttgcaatcctaccaacgcatggac cacagtaacaaggactgcttcatctgctgtatcctctcccatggagacaagggcgtcatc tacggcactgatggacatgaggcccccatatatgagctgacatctcagttcactggtttg aagtgcccttcccttgctggaaaaccaaaagtgttttttattcaggcttgtcagggggat aactaccagaaaggtatacctgttgagactgattcagaggagcaaccctatttagaaatg gacttatcatcacctcagacgagatatatcccagatgaggctgactttctactggggatg gccactgtgaataactgtgtttcctaccgaaaccctgcggagggaacctggtatatccag tcactttgccagagtctgagagaacggtgtcctcgaggcgatgatattctcgccatcctg actgaagtgaactatgaagtcagcaacaaagacgataagaagaacatggggaagcagatg ccgcagcccactttcacactaagaaaaaaacttgttttctcttctgattga

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