Aotus nancymaae (Ma's night monkey): 105722070
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Entry
105722070 CDS
T10127
Symbol
HSD11B1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1 isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
anan Aotus nancymaae (Ma's night monkey)
Pathway
anan00140
Steroid hormone biosynthesis
anan00980
Metabolism of xenobiotics by cytochrome P450
anan01100
Metabolic pathways
anan05204
Chemical carcinogenesis - DNA adducts
Module
anan_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
anan00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
105722070 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
105722070 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
105722070 (HSD11B1)
Enzymes [BR:
anan01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
105722070 (HSD11B1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
2-Hacid_dh_C
Shikimate_DH
Pyr_redox_3
Pyr_redox_2
AdoHcyase_NAD
Motif
Other DBs
NCBI-GeneID:
105722070
NCBI-ProteinID:
XP_012314673
Ensembl:
ENSANAG00000022488
UniProt:
A0A2K5CJR8
LinkDB
All DBs
Position
Unknown
AA seq
291 aa
AA seq
DB search
MAFMKKHLLPILGLFVAYYYYSAYEEFRPEMLQGKKVIVTGASKGIGREIAYHLAKMGAH
VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH
ITNTSLHFFHDDIHHVRKSMEVNFLSYVVLTVAAVPMLKQSNGSIVVVSSVAGKVAYPMI
SAYSASKFALDGFFSSIRKEYLMAEVNVSITLCVLGLIDTDTAMKAVSGIINMQAAPKEE
CALEIIKGGVLRQEEVYYDSSLWTTLLLRNPSRKILEFLRSTSYSTDRLIN
NT seq
876 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaacatctcctccccattctggggctcttcgtggcctactactac
tattctgcgtatgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggcgccagcaaagggatcggaagagaaatagcttatcatctggcgaagatgggagcccat
gtggtggtgacagcgaggtcaaaagaaactctacagaaggtggtatcccactgcctggag
cttggagcagcctcagcacactacattgctggcaccatggaagacatgaccttcgcagag
caatttgttgcccaagcgggaaagctcatgggaggactagacatgctcattctcaaccac
atcaccaacacttccttgcatttttttcatgatgacattcaccatgtgcgcaaaagcatg
gaggtcaacttcctcagttacgtggtcctgactgtggctgccgtgcccatgctgaagcag
agcaatggaagcattgtggtcgtctcctctgtggctggaaaagtggcttatccaatgatt
tctgcctattctgcaagcaagtttgctttggatgggttcttctcctccatcagaaaggaa
tatttaatggctgaggtcaatgtgtcaatcactctctgtgttctcggcctcatagacaca
gacacagccatgaaggcagtctctgggataatcaatatgcaagcggctccgaaggaggaa
tgtgccctggagataatcaaagggggagttctgcgccaagaggaagtgtattatgacagc
tcactctggaccactctcctgctgagaaatccatccaggaagatcctggaatttctccgt
tcgacgagttacagtacggacagattgataaactag
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