Aotus nancymaae (Ma's night monkey): 105732981 Help Entry 105732981         CDS       T10127                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism anan  Aotus nancymaae (Ma's night monkey) Pathway anan00230   Purine metabolism anan01100   Metabolic pathways anan01522   Endocrine resistance anan04015   Rap1 signaling pathway anan04020   Calcium signaling pathway anan04022   cGMP-PKG signaling pathway anan04024   cAMP signaling pathway anan04062   Chemokine signaling pathway anan04072   Phospholipase D signaling pathway anan04081   Hormone signaling anan04082   Neuroactive ligand signaling anan04114   Oocyte meiosis anan04211   Longevity regulating pathway anan04213   Longevity regulating pathway - multiple species anan04261   Adrenergic signaling in cardiomyocytes anan04270   Vascular smooth muscle contraction anan04371   Apelin signaling pathway anan04540   Gap junction anan04611   Platelet activation anan04713   Circadian entrainment anan04714   Thermogenesis anan04723   Retrograde endocannabinoid signaling anan04724   Glutamatergic synapse anan04725   Cholinergic synapse anan04727   GABAergic synapse anan04750   Inflammatory mediator regulation of TRP channels anan04911   Insulin secretion anan04912   GnRH signaling pathway anan04913   Ovarian steroidogenesis anan04914   Progesterone-mediated oocyte maturation anan04915   Estrogen signaling pathway anan04916   Melanogenesis anan04918   Thyroid hormone synthesis anan04921   Oxytocin signaling pathway anan04922   Glucagon signaling pathway anan04923   Regulation of lipolysis in adipocytes anan04925   Aldosterone synthesis and secretion anan04926   Relaxin signaling pathway anan04927   Cortisol synthesis and secretion anan04928   Parathyroid hormone synthesis, secretion and action anan04934   Cushing syndrome anan04935   Growth hormone synthesis, secretion and action anan04970   Salivary secretion anan04971   Gastric acid secretion anan04972   Pancreatic secretion anan04976   Bile secretion anan05032   Morphine addiction anan05163   Human cytomegalovirus infection anan05166   Human T-cell leukemia virus 1 infection anan05200   Pathways in cancer anan05207   Chemical carcinogenesis - receptor activation anan05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:anan00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105732981 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105732981 (ADCY2)    04371 Apelin signaling pathway     105732981 (ADCY2)    04020 Calcium signaling pathway     105732981 (ADCY2)    04072 Phospholipase D signaling pathway     105732981 (ADCY2)    04024 cAMP signaling pathway     105732981 (ADCY2)    04022 cGMP-PKG signaling pathway     105732981 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     105732981 (ADCY2)    04081 Hormone signaling     105732981 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105732981 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     105732981 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105732981 (ADCY2)    04062 Chemokine signaling pathway     105732981 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     105732981 (ADCY2)    04922 Glucagon signaling pathway     105732981 (ADCY2)    04923 Regulation of lipolysis in adipocytes     105732981 (ADCY2)    04912 GnRH signaling pathway     105732981 (ADCY2)    04913 Ovarian steroidogenesis     105732981 (ADCY2)    04915 Estrogen signaling pathway     105732981 (ADCY2)    04914 Progesterone-mediated oocyte maturation     105732981 (ADCY2)    04921 Oxytocin signaling pathway     105732981 (ADCY2)    04926 Relaxin signaling pathway     105732981 (ADCY2)    04935 Growth hormone synthesis, secretion and action     105732981 (ADCY2)    04918 Thyroid hormone synthesis     105732981 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     105732981 (ADCY2)    04916 Melanogenesis     105732981 (ADCY2)    04925 Aldosterone synthesis and secretion     105732981 (ADCY2)    04927 Cortisol synthesis and secretion     105732981 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105732981 (ADCY2)    04270 Vascular smooth muscle contraction     105732981 (ADCY2)   09154 Digestive system    04970 Salivary secretion     105732981 (ADCY2)    04971 Gastric acid secretion     105732981 (ADCY2)    04972 Pancreatic secretion     105732981 (ADCY2)    04976 Bile secretion     105732981 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     105732981 (ADCY2)    04727 GABAergic synapse     105732981 (ADCY2)    04725 Cholinergic synapse     105732981 (ADCY2)    04723 Retrograde endocannabinoid signaling     105732981 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     105732981 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     105732981 (ADCY2)    04213 Longevity regulating pathway - multiple species     105732981 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     105732981 (ADCY2)    04714 Thermogenesis     105732981 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105732981 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     105732981 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105732981 (ADCY2)    05163 Human cytomegalovirus infection     105732981 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     105732981 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105732981 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105732981 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105732981 (ADCY2) Enzymes [BR:anan01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105732981 (ADCY2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  105732981 NCBI-ProteinID:  XP_021531042 Ensembl:  ENSANAG00000023768 LinkDB All DBs Position Unknown AA seq 1091 aa AA seqDB search MWQEAMRRRRYLRDRAEEAAGGGDGLPRSRDWLYESYYCMSQQHPLIVFLLLIVMGACLA LLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWICLVAM GYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSAT PGAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQ ERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFT RLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVK MGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGG VPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPR HTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTL RTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKVLEKEYRATALPAF KYYVTCACLIFFCIFIVQILVLPKTSVLGISFGTAFLLLAFILFVCFAGQLLQCSKKASP PLMWLLKSSGIIANRPWPRISLTIVTTAIILTMAVFNMFFLSDSEETIPPTANTSNTSFS ALNNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNTILLHT HAHVLGDYSQVLFERPGIWKDLKTMGSVSLSIFFITLLVLGRQNEYYCRLDFLWKNKFKK EREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYHQSYDCVCVMFASIPDFKEFY TESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHA QEPERQYMHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDI WGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFVNTEM SRSLSQSNVAS NT seq 3276 nt NT seq  +upstreamnt  +downstreamnt atgtggcaggaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggaggcggcg ggcggcggagacgggctgccgcggtcccgggactggctctacgagtcctactactgcatg agccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggcgcctgcctcgcc ctgctcgccgtcttcttcgcgctcgggctggaagttgaagaccatgtggcatttttaata acagttccaactgccctggcaattttctttgcgatatttatcctggtctgcattgagtct gtgtttaagaagctgctgcgcctcttctcattggtgatatggatatgccttgttgccatg ggatacctcttcatgtgtttcggaggcactgtctctccctgggaccaggtatcattcttc ctcttcatcatcttcgtggtgtacactatgctgcccttcaacatgcgagatgccatcatt gccagtgtcctcacctcctcctcccacaccatcgtgcttagcgtctgcctgtctgcgaca ccgggggccaaggagcacctggtctggcagatcctggccaatgtgatcattttcatctgt gggaacctggcaggagcctaccataagcacctcatggagcttgctcttcagcaaacatat caggacacatgtaattgcatcaagtcccggatcaagttggaatttgaaaaacgtcaacag gagcggcttctgctgtccctgctgccggcccacatcgctatggagatgaaagcagagatc attcagaggctgcagggtcccaaggcgggccagatggagaacacaaataacttccacaac ctgtacgtgaagcggcataccaacgtgagcatcttatatgctgatatcgttggctttacc cggctggcaagtgactgctccccaggagaactcgtccacatgctgaatgagctcttcgga aagtttgatcaaattgcaaaggagaatgaatgcatgagaattaaaattttgggagactgc tactactgtgtatctggacttcctatatctctccctaaccatgccaagaactgtgtgaaa atgggactggacatgtgtgaagccataaagaaagtgagggatgctactggagttgatatc aacatgcgcgtgggtgtgcattctgggaacgtcctgtgtggcgtgattggtctgcagaag tggcagtacgatgtgtggtcccatgacgtgaccttggccaaccacatggaagctggaggg gtccctggacgtgttcacatttcttctgtcaccctggagcacttgaatggcgcttataaa gtagaggagggagatggtgacattagggacccatatttaaaacagcacctggtgaaaacc tacttcgtaatcaaccccaagggagaacgacggagccctcagcatctcttcagacctcgc cacaccctcgacggagccaaaatgagggcctcggtccgcatgacccggtacttggagtcc tggggggcagccaagccctttgcacacctacatcacagggacagcatgaccacagagaac ggcaagatcagcaccacggatgtaccgatgggtcagcataattttcaaaatcgcacctta agaaccaagtcacaaaagaaaagatttgaagaagaattgaatgaaaggatgattcaagca attgatggaatcaacgcacaaaagcaatggctcaagtctgaagatattcagagaatctca ctgcttttctataacaaagtactagaaaaagaataccgggccacggcactgccagcgttc aagtattacgtgacttgtgcctgtctcatattcttctgtatcttcattgtgcagattctc gtgctgccaaaaacatccgtcctgggcatctcctttgggactgcgtttctcttgctggcc ttcatcctcttcgtctgctttgctggacagcttctgcaatgcagcaaaaaagcttctccc ccgctcatgtggcttttgaagtcttccggcatcattgccaaccgcccctggccacggatt tctctgacgatcgtcaccacggccatcatactaaccatggccgtgttcaacatgtttttc ctgagtgactccgaggaaacaatccctccaactgccaatacatcaaacacaagtttttca gcgttaaataatcaggcagcgattctgcgtgcacaaaatttatttttcctcccgtacttt atatacagctgcattctgggactcatatcctgctccgtgttcctgcgggtgaactacgag ctgaagatgttgatcatgatggtggccttggtgggctacaacaccatcctgctccacacc cacgcccacgtcctgggtgactacagccaggtcttgtttgagagaccaggcatttggaaa gacctaaagaccatgggctctgtgtctctctctatattcttcatcacactgcttgttctg ggtagacagaatgaatattactgtaggttagacttcttatggaagaacaagttcaaaaaa gagcgggaggagatagagaccatggagaacctgaaccgcgtgctgctggagaacgtgctt cctgcgcacgtggctgagcacttcctggccaggagcctgaagaatgaggacctataccac cagtcctatgactgcgtctgcgtcatgtttgcctccattccggatttcaaagagttttat acagaatccgacgtgaacaaggagggcttggaatgccttcggctcctgaacgagatcatc gctgactttgatgatcttctgtccaagccaaaattcagtggagttgaaaagatcaagacc attggcagcacatacatggcagcgacaggtctgagcgctgtgcccagccaggagcatgcc caggagcctgagcggcagtacatgcacattggcaccatggtggagtttgcttttgctctg gtagcgaagctggatgccatcaacaagcactccttcaacgacttcaaactgcgagtgggt attaaccatggaccggtaatagctggtgtaattggagctcagaagccgcaatatgatatc tggggcaacaccgtcaatgtggccagtaggatggacagcactggagtcctggacaaaata caggtcaccgaggaaacaagcctcgtcctgcagaccctcggatacacgtgcacctgtcga ggaataatcaatgtgaaaggaaagggggacctgaagacgtactttgtaaacacggaaatg tcaaggtccctttcccagagcaacgtggcatcctga

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