KEGG   Arvicanthis niloticus (African grass rat): 117697279
Entry
117697279         CDS       T08817                                 
Symbol
Pten
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
anu  Arvicanthis niloticus (African grass rat)
Pathway
anu00562  Inositol phosphate metabolism
anu01100  Metabolic pathways
anu01521  EGFR tyrosine kinase inhibitor resistance
anu04068  FoxO signaling pathway
anu04070  Phosphatidylinositol signaling system
anu04071  Sphingolipid signaling pathway
anu04115  p53 signaling pathway
anu04140  Autophagy - animal
anu04150  mTOR signaling pathway
anu04151  PI3K-Akt signaling pathway
anu04218  Cellular senescence
anu04510  Focal adhesion
anu04931  Insulin resistance
anu05165  Human papillomavirus infection
anu05166  Human T-cell leukemia virus 1 infection
anu05200  Pathways in cancer
anu05206  MicroRNAs in cancer
anu05208  Chemical carcinogenesis - reactive oxygen species
anu05213  Endometrial cancer
anu05214  Glioma
anu05215  Prostate cancer
anu05218  Melanoma
anu05222  Small cell lung cancer
anu05224  Breast cancer
anu05225  Hepatocellular carcinoma
anu05230  Central carbon metabolism in cancer
anu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
anu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:anu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    117697279 (Pten)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    117697279 (Pten)
   04070 Phosphatidylinositol signaling system
    117697279 (Pten)
   04071 Sphingolipid signaling pathway
    117697279 (Pten)
   04151 PI3K-Akt signaling pathway
    117697279 (Pten)
   04150 mTOR signaling pathway
    117697279 (Pten)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    117697279 (Pten)
  09143 Cell growth and death
   04115 p53 signaling pathway
    117697279 (Pten)
   04218 Cellular senescence
    117697279 (Pten)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    117697279 (Pten)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117697279 (Pten)
   05206 MicroRNAs in cancer
    117697279 (Pten)
   05208 Chemical carcinogenesis - reactive oxygen species
    117697279 (Pten)
   05230 Central carbon metabolism in cancer
    117697279 (Pten)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    117697279 (Pten)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    117697279 (Pten)
   05214 Glioma
    117697279 (Pten)
   05218 Melanoma
    117697279 (Pten)
   05215 Prostate cancer
    117697279 (Pten)
   05213 Endometrial cancer
    117697279 (Pten)
   05224 Breast cancer
    117697279 (Pten)
   05222 Small cell lung cancer
    117697279 (Pten)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    117697279 (Pten)
   05165 Human papillomavirus infection
    117697279 (Pten)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    117697279 (Pten)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    117697279 (Pten)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    117697279 (Pten)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:anu01009]
    117697279 (Pten)
Enzymes [BR:anu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     117697279 (Pten)
    3.1.3.48  protein-tyrosine-phosphatase
     117697279 (Pten)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     117697279 (Pten)
Protein phosphatases and associated proteins [BR:anu01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    117697279 (Pten)
SSDB
Motif
Pfam: PTEN_C2 Tc-R-P PTP-SAK DSPc PTP-NADK Y_phosphatase PTPlike_phytase Y_phosphatase3 DUF3256
Other DBs
NCBI-GeneID: 117697279
NCBI-ProteinID: XP_034344177
LinkDB
Position
1:140013383..140083949
AA seq 403 aa
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHSQITKV
NT seq 1212 nt   +upstreamnt  +downstreamnt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaatattattgctatgggatttcctgcagaa
agacttgaaggtgtgtacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctatgtgctgagagacattatgacaccgccaaa
tttaactgcagagttgcacagtatccttttgaagaccataacccaccacagctagaattg
atcaaacccttctgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaatccactgtaaagctggaaagggacggactggtgtaatgatttgtgcatatttattg
catcggggcaaatttttaaaggcacaagaggccctagacttttatggggaagtaaggacc
agagacaaaaagggagtaacgattcccagtcagaggcgctatgtatattattatagctac
ctgttaaagaatcacctggattacagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggacccacgagacgggaggacaagttcatgtac
tttgagttccctcagccattgcctgtgtgtggtgacatcaaagtagagttcttccacaaa
cagaacaagatgctcaaaaaggacaaaatgtttcacttttgggtaaatacgttcttcata
ccaggaccagaggaaacctcagaaaaagtggaaaatggaagtctttgtgatcaggaaatc
gatagcatttgcagtatagaacgtgcagataatgacaaggagtatcttgtactcacccta
acaaaaaatgatcttgacaaagcaaacaaagacaaggccaaccgatacttctctccaaat
tttaaggtgaaattatactttacaaaaacagtagaggagccatcaaatccagaggctagc
agttcaacttctgtgactccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcattcacaaatt
acaaaagtctga

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