Arvicanthis niloticus (African grass rat): 117704516
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Entry
117704516 CDS
T08817
Symbol
Itch
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu04120
Ubiquitin mediated proteolysis
anu04144
Endocytosis
anu04330
Notch signaling pathway
anu04668
TNF signaling pathway
anu04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
117704516 (Itch)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
117704516 (Itch)
04668 TNF signaling pathway
117704516 (Itch)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
117704516 (Itch)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
117704516 (Itch)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
anu04131
]
117704516 (Itch)
04121 Ubiquitin system [BR:
anu04121
]
117704516 (Itch)
Enzymes [BR:
anu01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
117704516 (Itch)
Membrane trafficking [BR:
anu04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
117704516 (Itch)
Ubiquitin system [BR:
anu04121
]
Ubiquitin ligases (E3)
HECT type E3
117704516 (Itch)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
117704516
NCBI-ProteinID:
XP_034352574
LinkDB
All DBs
Position
2:124559807..124641097
Genome browser
AA seq
864 aa
AA seq
DB search
MSDSGPQLDSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPTSKLCFRVWSHQTLKSDVLLGTAGLDIYETLKSNNMKLEEVVMTL
QLVGDKEPTETMGDLSVCLDGLQVETEVVTNGETSCSESATQSDDGCRPRDETRVSTNGS
EDPEVAASGENKRASGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSTNSDSD
GSSTGSLPPTNTNVNTSTSEGATSGLIIPLTISGGSGPRPLNTVSQAPLPPGWEQRVNQH
GRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQ
WQLQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNH
NTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRATTYIDPRTGKSALDNG
PQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWV
IFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFR
FIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEEC
GLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE
GFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRSSKQIMWFWQFVKEI
DNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPP
YKSYEQLKEKLLFAIEETEGFGQE
NT seq
2595 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggaccacagcttgattcaatgggtagcctgaccatgaaatctcaactt
cagatcactgtcatctcagccaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtagaagttacagtagatgggcagtcaaagaagacagaaaaatgcaacaataca
aacagtcccaagtggaagcaacccctcacagttatcgttacccctacaagtaaattatgt
tttcgtgtgtggagtcaccagaccttgaaatctgatgttttattgggaactgctggatta
gatatttatgaaacattaaagtcaaacaatatgaaacttgaagaagtagttatgactttg
cagcttgtaggtgacaaagagccaacagagacaatgggagatttgtcagtttgtctcgat
gggctgcaagtggaaactgaagttgttacaaatggggaaacttcatgctcagagagtgct
acacagagtgatgatggctgcagacccagggatgaaacaagagtgagcacaaatggatca
gaggaccctgaggttgcagcatcaggggaaaacaagagggccagtggaaacaattctcca
tccctttcaaatggtggttttaagccttctagacctcctagaccttcgagaccacctcca
cccaccccacgaagaccagcttctgtcaatggctcaccatctacgaattctgacagtgat
ggatctagtacaggctctttgccaccaacaaatacaaatgtaaatacaagtacatccgaa
ggagcaacatctggattaataatccctcttactatatctggaggctcaggccccagaccc
ctgaatactgtaagccaagctcccctaccacctgggtgggagcagagagtaaaccagcat
gggcgtgtttactacgtagaccatgttgaaaagcgaacaacatgggacagaccggaacct
ctacctcctggctgggaacggcgtgtggacaatatgggacgtatttattatgttgaccat
ttcacaagaaccacaacatggcagaggccaaccttggaatctgtccggaactatgaacag
tggcagctacagcgtagtcagcttcagggagcaatgcagcagtttaaccagagattcatc
tatgggaatcaagatttgtttgctacatcacaaaacaaagaatttgatccccttggtcct
ttgccccctggatgggagaagagaactgatagcaacggaagagtatattttgtcaaccac
aacactcggattacacagtgggaagaccccagaagccaaggtcagttaaatgaaaagccc
ttaccagaaggctgggaaatgagattcacagtggacggaattccatattttgtggaccac
aatagaagagcaactacttatatagatccacgaacaggaaaatcagccttagacaatgga
ccccagatagcctatgttcgggacttcaaggcaaaagttcagtatttccggttctggtgt
cagcaactggccatgccacagcatataaagatcacagtgacaagaaaaaccttgtttgag
gattcctttcaacagatcatgagcttcagcccgcaagatctgagaagacgtttgtgggtg
attttcccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttctt
ttgtcacatgaagtgctgaacccaatgtattgcctgtttgaatatgcagggaaggataac
tactgcctgcagataaaccccgcttcttacatcaatccagaccacctgaaatacttccgt
tttattggcagatttattgccatggctctattccatgggaaattcatagatactggattt
tctttaccattctataaacgtatcctgaataaaccagttggacttaaggatttagaatct
attgatccagaattttacaattctctcatctgggttaaagaaaacaatatcgaagaatgt
ggtttggaaatgtacttctcagttgataaagaaattctaggtgaaattaagagtcatgat
ttgaaacccaatggtggcaatattcttgtgacagaagaaaataaggaggaatacatcagg
atggtagctgagtggaggttgtctcgaggtgttgaagagcagacacaagctttctttgag
ggctttaatgaaattcttccccagcaatatttgcaatattttgatgcgaaggaattagag
gtccttttgtgtggaatgcaagagattgatttgaatgactggcagagacatgccatctac
cgtcactacaccaggtcaagcaagcagatcatgtggttttggcagtttgttaaagaaatt
gataatgagaaaaggatgaggcttctgcagtttgttactggaacctgccgactgccagtg
ggaggatttgctgaccttatggggagtaatggaccacagaagttctgcattgaaaaagtt
ggcaaagaaaattggttacccagaagccatacttgttttaaccgcctggacctcccacca
tacaagagctacgagcaactgaaggaaaagctgttatttgccattgaagaaacagaagga
tttggacaagagtaa
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