KEGG   Arvicanthis niloticus (African grass rat): 117708961
Entry
117708961         CDS       T08817                                 
Symbol
Pik3r3
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
anu  Arvicanthis niloticus (African grass rat)
Pathway
anu01521  EGFR tyrosine kinase inhibitor resistance
anu01522  Endocrine resistance
anu01524  Platinum drug resistance
anu04012  ErbB signaling pathway
anu04014  Ras signaling pathway
anu04015  Rap1 signaling pathway
anu04024  cAMP signaling pathway
anu04062  Chemokine signaling pathway
anu04066  HIF-1 signaling pathway
anu04068  FoxO signaling pathway
anu04070  Phosphatidylinositol signaling system
anu04071  Sphingolipid signaling pathway
anu04072  Phospholipase D signaling pathway
anu04081  Hormone signaling
anu04140  Autophagy - animal
anu04145  Phagocytosis
anu04150  mTOR signaling pathway
anu04151  PI3K-Akt signaling pathway
anu04152  AMPK signaling pathway
anu04210  Apoptosis
anu04211  Longevity regulating pathway
anu04213  Longevity regulating pathway - multiple species
anu04218  Cellular senescence
anu04360  Axon guidance
anu04370  VEGF signaling pathway
anu04380  Osteoclast differentiation
anu04510  Focal adhesion
anu04517  IgSF CAM signaling
anu04518  Integrin signaling
anu04550  Signaling pathways regulating pluripotency of stem cells
anu04611  Platelet activation
anu04613  Neutrophil extracellular trap formation
anu04620  Toll-like receptor signaling pathway
anu04625  C-type lectin receptor signaling pathway
anu04630  JAK-STAT signaling pathway
anu04650  Natural killer cell mediated cytotoxicity
anu04660  T cell receptor signaling pathway
anu04662  B cell receptor signaling pathway
anu04664  Fc epsilon RI signaling pathway
anu04666  Fc gamma R-mediated phagosome formation
anu04668  TNF signaling pathway
anu04670  Leukocyte transendothelial migration
anu04722  Neurotrophin signaling pathway
anu04725  Cholinergic synapse
anu04750  Inflammatory mediator regulation of TRP channels
anu04810  Regulation of actin cytoskeleton
anu04910  Insulin signaling pathway
anu04914  Progesterone-mediated oocyte maturation
anu04915  Estrogen signaling pathway
anu04917  Prolactin signaling pathway
anu04919  Thyroid hormone signaling pathway
anu04923  Regulation of lipolysis in adipocytes
anu04926  Relaxin signaling pathway
anu04929  GnRH secretion
anu04930  Type II diabetes mellitus
anu04931  Insulin resistance
anu04932  Non-alcoholic fatty liver disease
anu04933  AGE-RAGE signaling pathway in diabetic complications
anu04935  Growth hormone synthesis, secretion and action
anu04960  Aldosterone-regulated sodium reabsorption
anu04973  Carbohydrate digestion and absorption
anu05010  Alzheimer disease
anu05017  Spinocerebellar ataxia
anu05020  Prion disease
anu05100  Bacterial invasion of epithelial cells
anu05135  Yersinia infection
anu05142  Chagas disease
anu05146  Amoebiasis
anu05160  Hepatitis C
anu05161  Hepatitis B
anu05162  Measles
anu05163  Human cytomegalovirus infection
anu05164  Influenza A
anu05165  Human papillomavirus infection
anu05166  Human T-cell leukemia virus 1 infection
anu05167  Kaposi sarcoma-associated herpesvirus infection
anu05168  Herpes simplex virus 1 infection
anu05169  Epstein-Barr virus infection
anu05170  Human immunodeficiency virus 1 infection
anu05171  Coronavirus disease
anu05200  Pathways in cancer
anu05203  Viral carcinogenesis
anu05205  Proteoglycans in cancer
anu05206  MicroRNAs in cancer
anu05207  Chemical carcinogenesis - receptor activation
anu05208  Chemical carcinogenesis - reactive oxygen species
anu05210  Colorectal cancer
anu05211  Renal cell carcinoma
anu05212  Pancreatic cancer
anu05213  Endometrial cancer
anu05214  Glioma
anu05215  Prostate cancer
anu05218  Melanoma
anu05220  Chronic myeloid leukemia
anu05221  Acute myeloid leukemia
anu05222  Small cell lung cancer
anu05223  Non-small cell lung cancer
anu05224  Breast cancer
anu05225  Hepatocellular carcinoma
anu05226  Gastric cancer
anu05230  Central carbon metabolism in cancer
anu05231  Choline metabolism in cancer
anu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
anu05415  Diabetic cardiomyopathy
anu05417  Lipid and atherosclerosis
anu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:anu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    117708961 (Pik3r3)
   04014 Ras signaling pathway
    117708961 (Pik3r3)
   04015 Rap1 signaling pathway
    117708961 (Pik3r3)
   04370 VEGF signaling pathway
    117708961 (Pik3r3)
   04630 JAK-STAT signaling pathway
    117708961 (Pik3r3)
   04668 TNF signaling pathway
    117708961 (Pik3r3)
   04066 HIF-1 signaling pathway
    117708961 (Pik3r3)
   04068 FoxO signaling pathway
    117708961 (Pik3r3)
   04070 Phosphatidylinositol signaling system
    117708961 (Pik3r3)
   04072 Phospholipase D signaling pathway
    117708961 (Pik3r3)
   04071 Sphingolipid signaling pathway
    117708961 (Pik3r3)
   04024 cAMP signaling pathway
    117708961 (Pik3r3)
   04151 PI3K-Akt signaling pathway
    117708961 (Pik3r3)
   04152 AMPK signaling pathway
    117708961 (Pik3r3)
   04150 mTOR signaling pathway
    117708961 (Pik3r3)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    117708961 (Pik3r3)
   04517 IgSF CAM signaling
    117708961 (Pik3r3)
   04518 Integrin signaling
    117708961 (Pik3r3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    117708961 (Pik3r3)
   04140 Autophagy - animal
    117708961 (Pik3r3)
  09143 Cell growth and death
   04210 Apoptosis
    117708961 (Pik3r3)
   04218 Cellular senescence
    117708961 (Pik3r3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    117708961 (Pik3r3)
   04550 Signaling pathways regulating pluripotency of stem cells
    117708961 (Pik3r3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    117708961 (Pik3r3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    117708961 (Pik3r3)
   04613 Neutrophil extracellular trap formation
    117708961 (Pik3r3)
   04620 Toll-like receptor signaling pathway
    117708961 (Pik3r3)
   04625 C-type lectin receptor signaling pathway
    117708961 (Pik3r3)
   04650 Natural killer cell mediated cytotoxicity
    117708961 (Pik3r3)
   04660 T cell receptor signaling pathway
    117708961 (Pik3r3)
   04662 B cell receptor signaling pathway
    117708961 (Pik3r3)
   04664 Fc epsilon RI signaling pathway
    117708961 (Pik3r3)
   04666 Fc gamma R-mediated phagosome formation
    117708961 (Pik3r3)
   04670 Leukocyte transendothelial migration
    117708961 (Pik3r3)
   04062 Chemokine signaling pathway
    117708961 (Pik3r3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    117708961 (Pik3r3)
   04923 Regulation of lipolysis in adipocytes
    117708961 (Pik3r3)
   04929 GnRH secretion
    117708961 (Pik3r3)
   04915 Estrogen signaling pathway
    117708961 (Pik3r3)
   04914 Progesterone-mediated oocyte maturation
    117708961 (Pik3r3)
   04917 Prolactin signaling pathway
    117708961 (Pik3r3)
   04926 Relaxin signaling pathway
    117708961 (Pik3r3)
   04935 Growth hormone synthesis, secretion and action
    117708961 (Pik3r3)
   04919 Thyroid hormone signaling pathway
    117708961 (Pik3r3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    117708961 (Pik3r3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    117708961 (Pik3r3)
  09156 Nervous system
   04725 Cholinergic synapse
    117708961 (Pik3r3)
   04722 Neurotrophin signaling pathway
    117708961 (Pik3r3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    117708961 (Pik3r3)
  09158 Development and regeneration
   04360 Axon guidance
    117708961 (Pik3r3)
   04380 Osteoclast differentiation
    117708961 (Pik3r3)
  09149 Aging
   04211 Longevity regulating pathway
    117708961 (Pik3r3)
   04213 Longevity regulating pathway - multiple species
    117708961 (Pik3r3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117708961 (Pik3r3)
   05206 MicroRNAs in cancer
    117708961 (Pik3r3)
   05205 Proteoglycans in cancer
    117708961 (Pik3r3)
   05207 Chemical carcinogenesis - receptor activation
    117708961 (Pik3r3)
   05208 Chemical carcinogenesis - reactive oxygen species
    117708961 (Pik3r3)
   05203 Viral carcinogenesis
    117708961 (Pik3r3)
   05230 Central carbon metabolism in cancer
    117708961 (Pik3r3)
   05231 Choline metabolism in cancer
    117708961 (Pik3r3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    117708961 (Pik3r3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    117708961 (Pik3r3)
   05212 Pancreatic cancer
    117708961 (Pik3r3)
   05225 Hepatocellular carcinoma
    117708961 (Pik3r3)
   05226 Gastric cancer
    117708961 (Pik3r3)
   05214 Glioma
    117708961 (Pik3r3)
   05221 Acute myeloid leukemia
    117708961 (Pik3r3)
   05220 Chronic myeloid leukemia
    117708961 (Pik3r3)
   05218 Melanoma
    117708961 (Pik3r3)
   05211 Renal cell carcinoma
    117708961 (Pik3r3)
   05215 Prostate cancer
    117708961 (Pik3r3)
   05213 Endometrial cancer
    117708961 (Pik3r3)
   05224 Breast cancer
    117708961 (Pik3r3)
   05222 Small cell lung cancer
    117708961 (Pik3r3)
   05223 Non-small cell lung cancer
    117708961 (Pik3r3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    117708961 (Pik3r3)
   05170 Human immunodeficiency virus 1 infection
    117708961 (Pik3r3)
   05161 Hepatitis B
    117708961 (Pik3r3)
   05160 Hepatitis C
    117708961 (Pik3r3)
   05171 Coronavirus disease
    117708961 (Pik3r3)
   05164 Influenza A
    117708961 (Pik3r3)
   05162 Measles
    117708961 (Pik3r3)
   05168 Herpes simplex virus 1 infection
    117708961 (Pik3r3)
   05163 Human cytomegalovirus infection
    117708961 (Pik3r3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    117708961 (Pik3r3)
   05169 Epstein-Barr virus infection
    117708961 (Pik3r3)
   05165 Human papillomavirus infection
    117708961 (Pik3r3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    117708961 (Pik3r3)
   05100 Bacterial invasion of epithelial cells
    117708961 (Pik3r3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    117708961 (Pik3r3)
   05142 Chagas disease
    117708961 (Pik3r3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    117708961 (Pik3r3)
   05017 Spinocerebellar ataxia
    117708961 (Pik3r3)
   05020 Prion disease
    117708961 (Pik3r3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    117708961 (Pik3r3)
   05418 Fluid shear stress and atherosclerosis
    117708961 (Pik3r3)
   05415 Diabetic cardiomyopathy
    117708961 (Pik3r3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    117708961 (Pik3r3)
   04932 Non-alcoholic fatty liver disease
    117708961 (Pik3r3)
   04931 Insulin resistance
    117708961 (Pik3r3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    117708961 (Pik3r3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    117708961 (Pik3r3)
   01524 Platinum drug resistance
    117708961 (Pik3r3)
   01522 Endocrine resistance
    117708961 (Pik3r3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:anu04131]
    117708961 (Pik3r3)
Membrane trafficking [BR:anu04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    117708961 (Pik3r3)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 SH2_1 Bap31_Bap29_C DicA_C ODF2_C Legum_prodom CC2-LZ
Other DBs
NCBI-GeneID: 117708961
NCBI-ProteinID: XP_076790515
LinkDB
Position
5:complement(36864087..36948217)
AA seq 461 aa
MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSEVTNGMKDSFVSL
QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
KYGFSEPLTFNSVVELISHYRHESLAQYNPKLDVKLTYPVSRYQQDQLVKEDNIDAVGKN
LQEFHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQYSKDY
IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKVRLEQDLKKQALDNREIDKKMNSIKP
DLIQLRKIRDQHLVWLNHRGVRQRRLNAWLGIKNEDMDESCFINEDDENLPHYDEKTWFV
EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
NT seq 1386 nt   +upstreamnt  +downstreamnt
atgtacaatacggtgtggagtatggaccgcgatgacgcagactggagggaggtgatgatg
ccctattcgacagaactgatattttatattgaaatggatcctccagctcttccaccaaag
ccgcctaagccaatgacatcagaggttacaaatggaatgaaggacagttttgtttctctt
caagatgcagagtggtactggggtgatatttccagggaagaggtaaatgacaaattgcgg
gacatgccagatggtaccttcttagttcgtgatgcctcaacaaaaatgcagggggactat
acattgaccttgaggaagggaggaaataataagttaataaagatctatcatcgggatggt
aaatacggcttctctgagccactgacgtttaattctgtggtggagctcatcagccactat
cgccatgagtctctggctcagtacaaccccaaactcgacgtgaagctgacgtacccagtg
tcgagataccaacaggatcagttggtaaaagaagataacattgatgcagtaggtaaaaac
ctgcaagagttccactctcagtatcaggagaagagcaaagaatatgataggctgtatgaa
gaatacaccagaacgtcacaggagatccagatgaagaggaccgccattgaagccttcaat
gagacgattaagatatttgaggagcagtgtcatacccaggaacagtacagtaaagactac
atcgagcggtttcgcagagaggggaatgagaaggagattgagcgaattatgatgaattat
gacaaattgaaatcacgtcttggtgagattcatgatagcaaagtgcgtcttgagcaggac
ttgaagaaacaagctttggacaaccgggaaatagataaaaaaatgaatagcatcaaacct
gacctgatccagctccgtaagatccgagatcagcaccttgtatggctcaatcacagagga
gtgaggcagaggcgcctgaacgcctggctggggatcaagaacgaggacatggatgaaagc
tgttttatcaatgaggacgatgagaacctgccacattacgatgagaaaacctggtttgtg
gaggatatcaaccgagtacaagcagaggacttgctttatgggaaaccagatggtgcattc
ttaattcgtgagagtagcaaaaaaggatgttatgcttgttctgtggttgcagacggggaa
gtgaagcactgtgtcatctatagcactgctcgcggatacggctttgcagagccctacaac
ctgtacagctcactgaaggagctggtgctccactaccagcagacgtccctggttcagcac
aacgactccctcaatgtcaggctcgcctaccctgtccacgcacagatgccttcgctctgc
agataa

DBGET integrated database retrieval system