Arvicanthis niloticus (African grass rat): 117718073
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Entry
117718073 CDS
T08817
Symbol
Bace2
Name
(RefSeq) beta-secretase 2
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
117718073 (Bace2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
anu01002
]
117718073 (Bace2)
Enzymes [BR:
anu01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
117718073 (Bace2)
Peptidases and inhibitors [BR:
anu01002
]
Aspartic peptidases
Family A1: pepsin family
117718073 (Bace2)
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Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
117718073
NCBI-ProteinID:
XP_034371467
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All DBs
Position
12:78718080..78807396
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AA seq
514 aa
AA seq
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MGALLRALLLPLLAQWLLSAVPALAPAPFTLPLQVAGATNHRASAVPGLGTPELPRADGL
ALALEPARATANFLAMVDNLQGDSGRGYYLEMLIGTPPQKVQILVDTGSSNFAVAGAPHS
YIDTYFDSESSSTYRPKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNSSFLVNIATIFESE
NFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDIFSMQMCGAGLPVAGSGT
NGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRD
ENASRSFRITILPQLYIQPMMGAGFNYECYRFGISSSTNALVIGATVMEGFYVVFDRAQR
RVGFAVSPCAEIAGTTVSEISGPFSTEDIASNCVPAQALNEPILWIVSYALMSVCGAILL
VLIFLLLLPLHCRHAPRDPEVVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctgcttcgagcactcttgctcccgctgctggcgcagtggctcttgagcgca
gtccctgcgctggcccccgcgcccttcacgctgcccctccaagtggccggggccacgaac
cacagagcctcggctgttcccgggctcgggaccccagagttgccccgggccgatggcctg
gccctcgcactggagcctgccagggctaccgccaacttcttggctatggtggacaacctt
cagggggactctggccgcggctactacctggagatgctgatcgggacccctccgcagaag
gtacagattcttgtggacaccggaagcagtaacttcgctgtggcaggtgccccacactcc
tacatagacacctactttgactcagagagctccagcacataccgccccaagggctttgat
gtcactgtgaagtacacacagggaagctggactggctttgttggtgaggaccttgtcacg
atcccaaaaggcttcaacagctctttcttggtcaatattgccactattttcgagtctgag
aatttctttttgcctgggattaaatggaatggaatccttggacttgcttatgctgctttg
gccaagccatcaagttctctggagaccttttttgattccctggtggcccaagcaaagatt
ccagacattttctccatgcagatgtgtggggctggattgccagtagctggatctggtacc
aacggaggtagtcttgtccttggtgggattgaaccaagtttgtataaaggagatatctgg
tataccccgattaaagaggaatggtactatcaaatagagatcctgaaattggaaattgga
ggccagagcctcaacctggactgtagagagtataatgcagacaaggccattgtggacagt
ggcactacgctcctgcgcctgccccagaaggtgtttgatgcagtggtggaagctgtggca
cgcacatctctgattccagagttttctgatggcttctggacaggggcccagctggcatgc
tggacaaattctgaaacaccatgggcatatttccctaagatttctatctacctgagagat
gagaacgccagtcgctccttccggatcaccattctgccgcagctctacattcagcccatg
atgggagctgggttcaattatgaatgctaccgttttggcatctcctcttccacaaatgca
ctggtgattggtgccaccgtgatggaaggcttctatgtggtctttgacagagctcagagg
agggtgggctttgcagtgagtccctgtgcagagattgcaggtaccacagtgtctgaaatt
tctgggcccttttccacggaagacatagccagcaactgtgttccagcacaggctctgaat
gagcccatcttgtggattgtgtcttatgctctgatgagtgtgtgcggagccattctcctg
gttctgatcttcctgctgctgctcccgttgcactgccgacatgccccccgagaccctgag
gtggttaatgatgagtcctcactagtcagacatcgctggaaatga
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