KEGG   Arvicanthis niloticus (African grass rat): 143436221
Entry
143436221         CDS       T08817                                 
Symbol
Mdm2
Name
(RefSeq) E3 ubiquitin-protein ligase Mdm2 isoform X1
  KO
K06643  E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
Organism
anu  Arvicanthis niloticus (African grass rat)
Pathway
anu01522  Endocrine resistance
anu01524  Platinum drug resistance
anu04068  FoxO signaling pathway
anu04110  Cell cycle
anu04115  p53 signaling pathway
anu04120  Ubiquitin mediated proteolysis
anu04144  Endocytosis
anu04151  PI3K-Akt signaling pathway
anu04218  Cellular senescence
anu04625  C-type lectin receptor signaling pathway
anu04919  Thyroid hormone signaling pathway
anu05163  Human cytomegalovirus infection
anu05165  Human papillomavirus infection
anu05169  Epstein-Barr virus infection
anu05200  Pathways in cancer
anu05202  Transcriptional misregulation in cancer
anu05203  Viral carcinogenesis
anu05205  Proteoglycans in cancer
anu05206  MicroRNAs in cancer
anu05214  Glioma
anu05215  Prostate cancer
anu05218  Melanoma
anu05219  Bladder cancer
anu05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:anu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    143436221 (Mdm2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    143436221 (Mdm2)
   04151 PI3K-Akt signaling pathway
    143436221 (Mdm2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    143436221 (Mdm2)
  09143 Cell growth and death
   04110 Cell cycle
    143436221 (Mdm2)
   04115 p53 signaling pathway
    143436221 (Mdm2)
   04218 Cellular senescence
    143436221 (Mdm2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    143436221 (Mdm2)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    143436221 (Mdm2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    143436221 (Mdm2)
   05202 Transcriptional misregulation in cancer
    143436221 (Mdm2)
   05206 MicroRNAs in cancer
    143436221 (Mdm2)
   05205 Proteoglycans in cancer
    143436221 (Mdm2)
   05203 Viral carcinogenesis
    143436221 (Mdm2)
  09162 Cancer: specific types
   05214 Glioma
    143436221 (Mdm2)
   05220 Chronic myeloid leukemia
    143436221 (Mdm2)
   05218 Melanoma
    143436221 (Mdm2)
   05219 Bladder cancer
    143436221 (Mdm2)
   05215 Prostate cancer
    143436221 (Mdm2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    143436221 (Mdm2)
   05169 Epstein-Barr virus infection
    143436221 (Mdm2)
   05165 Human papillomavirus infection
    143436221 (Mdm2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    143436221 (Mdm2)
   01522 Endocrine resistance
    143436221 (Mdm2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:anu04131]
    143436221 (Mdm2)
   04121 Ubiquitin system [BR:anu04121]
    143436221 (Mdm2)
Enzymes [BR:anu01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     143436221 (Mdm2)
Membrane trafficking [BR:anu04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    143436221 (Mdm2)
Ubiquitin system [BR:anu04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   MDM2/MDM4 proteins
    143436221 (Mdm2)
SSDB
Motif
Pfam: zf-C3HC4_3 Zn_ribbon_RanBP SWIB zf-RING_2 JetB zf-FPG_IleRS
Other DBs
NCBI-GeneID: 143436221
NCBI-ProteinID: XP_076776420
LinkDB
Position
22:complement(39476037..39499848)
AA seq 495 aa
MCNTNMSVSAEGAASTSQIPASEQETLVRPKPLLLKLLKFVGAQKDTYTMKEIIFYIGQY
IMTKRLYDEKQQHIVYCSNDLLGDVFGVSSFSVKEHRKIYAMIYRNLVVVSQQDSGPSMS
ESRCQPEGGSDLKDPVQAPQEENPSSSDLVSRPSTSSRRRAISETEENTDELPGERQRKR
HRSLSFDESLGLCVLREICCEGSSSSSSSSSSSSSSSSESMEAASQQDPDDGLSEHSGDC
LDQDSVSDQFSVEFEVESLDSEDYSLSDEGHELSDEDDEVYRVTVYQAGESDADSFEEDP
EISLADYWKCSSCSEMNPPLPSHCNRCWTLRENWLPEDKGKDKVAISEKVKLENSAQAEE
GLDVPDGKKLTENDAKDLYAEDPEEKATQMPLSQESDDYSQPSTSSSIVYSSQESVRELK
EETQDKEESMESSFSVNAVEPCVICQGRPKNGCIVHGKTGHLMSCFTCAKKLKKRNKPCP
VCRQPIQMIVLTYFS
NT seq 1488 nt   +upstreamnt  +downstreamnt
atgtgcaataccaacatgtctgtgtctgccgagggtgctgcaagcacctcacagattcca
gcttcggaacaagagactctggttagaccaaaaccattgcttttgaagttgttgaagttc
gttggagcacagaaagatacgtacactatgaaagagattatcttttatattggccagtat
attatgactaaaagactgtatgacgagaagcagcagcacattgtgtactgctctaacgat
cttctaggagatgtgtttggagtctccagtttctctgtgaaggagcacaggaaaatatat
gcaatgatctacagaaacttagtggttgtaagtcagcaagactctggcccatcgatgagt
gagagcagatgccagcctgaaggtgggagtgacctaaaggaccctgtgcaagcgccacaa
gaagagaacccttcttcttctgatttagtttctagaccgtctacctcatctagaaggaga
gcaattagtgagacagaagagaacacagatgaactgcctggtgaacgacagagaaagcgc
cacagatcgctgtcctttgatgagagcctgggtctgtgtgtgctgagggagatctgctgt
gagggaagcagcagcagcagcagcagcagtagcagcagcagcagtagcagcagcgagtcc
atggaggccgcctcgcagcaggatcctgatgatggcctaagtgaacattccggtgactgc
ctggatcaggattcagtttctgatcagtttagtgtagaatttgaagttgaatctcttgac
tcggaagattacagcctgagtgacgaagggcacgagctctcagatgaggatgatgaggtc
taccgggtcaccgtctatcaggcaggagaaagtgatgcggactcttttgaggaagatcct
gaaatttccttagctgactattggaaatgtagctcgtgcagtgagatgaacccgcccctt
ccatcacactgcaacagatgctggaccctccgggagaactggcttccagaagacaaaggg
aaagataaagtggctatctctgaaaaagtcaaactggaaaactcagctcaggcagaagaa
ggcttagatgtgcctgatggcaaaaaactgacagagaatgatgctaaggacttgtatgcc
gaggaccctgaggagaaagccacacagatgcccctgtcacaggagagtgacgactattcc
cagccatccacctccagcagcattgtttatagcagccaagaaagcgtccgagagttgaag
gaagagacacaggacaaagaggaaagcatggagtctagcttctctgtgaatgccgtcgaa
ccgtgtgtgatttgccaggggcggcccaaaaatggttgcattgttcacggcaaaaccgga
cacctcatgtcatgtttcacatgtgcaaagaagctaaagaaaaggaacaagccctgccca
gtgtgcagacagcctatccaaatgatcgtgctgacttacttcagttag

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