Amycolatopsis orientalis: SD37_06840
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Entry
SD37_06840 CDS
T06703
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
aori
Amycolatopsis orientalis
Pathway
aori00020
Citrate cycle (TCA cycle)
aori00630
Glyoxylate and dicarboxylate metabolism
aori00785
Lipoic acid metabolism
aori01100
Metabolic pathways
aori01110
Biosynthesis of secondary metabolites
aori01120
Microbial metabolism in diverse environments
aori01200
Carbon metabolism
aori01210
2-Oxocarboxylic acid metabolism
Module
aori_M00009
Citrate cycle (TCA cycle, Krebs cycle)
aori_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
aori00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SD37_06840 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
SD37_06840 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SD37_06840 (kgd)
Enzymes [BR:
aori01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SD37_06840 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SD37_06840 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SD37_06840 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SD37_06840 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ANN15397
UniProt:
A0A193BT58
LinkDB
All DBs
Position
complement(1412576..1416247)
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AA seq
1223 aa
AA seq
DB search
MYDQFLADPTSVDAAWHDFFADFKPTQAAQTKADDARQTVKDGPGTNGQASTPSPQTVRN
AESTAKQTAPKTEAKAPAKPAPKTEAKAAAPKAAPAKAPAKAPAKPAEKDAEPESKQLRG
AAAAIAKNMDASLSVPTATSVRAVPAKLMADNRIVINNHLKRTRGGKISFTHLIGYAMVR
ALKDFPNMNRHYQLIDGKPFAITPEHVNFGLAIDMKGKEGSRTLVVASIKATENMTFMQF
WQAYEDIVKKARTGKLTADDFAGTTISLTNPGGIGTNHSVPRLQAGQGAIIGVGAMQYPA
HFEGTSEKALVDLGVSKIMTLTSTYDHRIIQGAESGEFLKRIHELLLGEDGFYDDVFTSL
RLPYEPIRWVADIPDGPVDKTARVIELIDAFRMRGHLMADTDPLNYRQRSHADLDVLSHG
LTLWDLDREFPVGGFAGQERMKLRDILGVLRNSYCRTVGIEYTHILDPEERRWIQDRVEI
PHEKPDPAVQKYVLSKLNAAEAFETFLQTKYVGQKRFSLEGGETAIPLLDTILDKAAEHE
LDEVVIGMPHRGRLNVLANIVGKPIAQIFQEFEGNLDPGQAHGSGDVKYHLGAEGKYFRM
FGDGETKVSLTANPSHLETVDPVLEGIVRAKQDILDKGGEGFTVLPVLMHGDAAFAGQGV
VAETLNLALLRGYRTGGTVHVIVNNQVGFTTAPEHSRSSQYATDVAKMIGSPIFHVNGDD
PEAAHWVAKLAVDYRQAFHKDVVIDLICYRRRGHNEGDDPSMTQPAMYDIIDTKRSVRKT
YTESLIGRGDISVEEAEAALRDFSSQLEHVFNEVRELEKHPAKASPSVEEEQQVPAKVPT
ATTTEVIEHIGDAFLNVPEGFTPHPRVKPVMERRHKMSREGGIDWAFGELLAFGSLAMEG
RLVRLSGQDSRRGTFTQRHSVLIDRKNGQEYSPLASLAEGQGRVMIYDSALSEYAAVGFE
YGYSVANSEALVMWEAQFGDFVNGAQTVIDEYISSGEAKWGQLSDVVLLLPHGHEGQGPD
HTSGRIERFLSLCAEGSMTVAVPSTPANYFHLLRRHALDGVNRPLVVFTPKSMLRNKAAT
SAVEDFTGQSKFMSVIDDAVVDPSKVRKVLLTSGKLYWELVAERTKREANDIAIVRVEQY
YPLPKKKLVAALERYNGAPAVWVQEEPENQGAWPFFGLNLPRKLPEVFSSLDVVSRRPMA
APSAGSSKVHEVEQKALIARAFD
NT seq
3672 nt
NT seq
+upstream
nt +downstream
nt
atgtacgaccagttcctcgccgaccccacctcagtcgatgccgcctggcacgacttcttc
gcggacttcaagccaacgcaggccgcgcagacgaaggctgacgacgcacgtcagaccgtc
aaggatggcccgggcaccaacggccaggcctccacgccgtcgccgcagacggtccgcaac
gccgagtccaccgcgaagcagaccgctccgaagacggaggcgaaggcgcccgcgaagccg
gccccgaagaccgaagcgaaggcggccgcgcccaaggcggcccccgcgaaggccccggcg
aaggctcccgccaagccggccgagaaggacgccgagccggagtcgaagcagctccgtggc
gccgcggccgcgatcgcgaagaacatggacgcctcgctgtcggtgccgacagcgacgagt
gtgcgcgccgtcccggcgaagttgatggccgacaaccgcatcgtcatcaacaaccacctc
aagcgcacgcgcggcggaaagatctccttcacgcacctcatcggttacgcgatggtccgt
gcgctgaaggacttcccgaacatgaaccggcactaccagctgatcgacgggaagccgttc
gcgatcacgccggagcacgtgaacttcggtctcgcgatcgacatgaagggcaaggaaggc
tcccgcacgctcgtcgtggcctccatcaaggccaccgagaacatgaccttcatgcagttc
tggcaggcctacgaagacatcgtcaagaaggcccgcaccggcaagctgaccgccgacgac
ttcgccggcaccacgatctcgctgaccaaccccggcgggatcggcaccaaccactcggtg
ccgcggctgcaggccggtcagggcgcgatcatcggcgtcggcgccatgcagtacccggcg
cacttcgagggcaccagcgagaaggccctggtcgacctcggcgtctcgaagatcatgacg
ctgacctcgacctatgaccaccgcatcatccagggtgcggagtcgggcgagttcctcaag
cgaatccacgagctgctgctgggcgaggacggcttctacgacgacgtcttcaccagcctg
cgcctgccgtacgagccgatccgctgggtcgccgacatcccggacggcccggtcgacaag
accgcgcgcgtgatcgagctgatcgacgccttccgcatgcgcggtcacctgatggccgac
accgacccgctgaactaccggcagcgcagccacgccgacctcgacgtcctctcccacggc
ctgaccctgtgggacctggaccgcgagttcccggtcggcggcttcgccggccaggagcgg
atgaagctgcgtgacatcctcggggtgctgcgcaactcctactgccgcaccgtgggcatc
gagtacacgcacatcctcgaccccgaagagcgccgctggatccaggaccgcgtcgagatc
ccgcacgagaagccggaccccgccgtccagaagtacgtgctctcgaagctcaacgccgcc
gaggcgttcgagaccttcctgcagaccaagtacgtcggccagaagcggttctccctcgaa
ggcggcgagaccgcgatcccgctgctggacaccatcctggacaaggccgccgagcacgaa
ctcgacgaggtcgtcatcggcatgccgcaccgcggccgcctgaacgtgctcgcgaacatc
gtcggcaagccgatcgcgcagatcttccaggagttcgagggcaacctcgacccgggccag
gcgcacggctccggtgacgtgaagtaccacctcggtgccgagggcaagtacttccgcatg
ttcggcgacggcgagaccaaggtgtcgctgaccgcgaacccgtcgcacctggagaccgtc
gacccggtcctcgagggcatcgtccgcgcgaagcaggacatcctcgacaagggtggcgag
ggcttcaccgtcctccccgtcctcatgcacggcgacgcggccttcgcgggccagggtgtc
gtggccgagaccctgaacctggcgctgctgcgcggttaccgcaccggcggcaccgtgcac
gtcatcgtcaacaaccaggtcggcttcaccaccgcgcccgagcactcgcggtcgagccag
tacgccaccgacgtcgcgaagatgatcggctcgccgatcttccacgtgaacggtgacgac
cccgaggccgcgcactgggtggccaagctggccgtcgactaccgccaggcgttccacaag
gacgtcgtgatcgacctgatctgctaccgccgccgcggccacaacgagggcgacgaccct
tcgatgacgcagccggcgatgtacgacatcatcgacacgaagcgttcggtccggaagacc
tacaccgaatcgctgatcggccgcggcgacatctccgtcgaagaggccgaagccgcgttg
cgtgacttctccagccagctggagcacgtcttcaacgaggtccgcgagctggagaagcac
ccggcgaaggccagcccctcggtcgaagaggagcagcaggtcccggccaaggtgcccacc
gccaccaccaccgaggtcatcgagcacatcggggacgcgttcctcaacgtgcccgagggc
ttcaccccgcacccgcgggtcaagccggtcatggagcgccgccacaagatgtcccgcgaa
ggcggcatcgactgggcgttcggcgagctgctcgcgttcggctcgctggccatggaaggc
cgcctggtgcggctgtccggccaggactcccgccgcggcaccttcacccagcgccactcg
gtgctgatcgaccgcaagaacggccaggagtactcgccgctggcgagcctggccgagggc
cagggccgcgtgatgatctacgactcggcgctgtccgagtacgcggcggtcggcttcgaa
tacggctactccgtggccaactccgaagcgctggtcatgtgggaagcgcagttcggtgac
ttcgtcaacggcgcgcagaccgtcatcgacgagtacatctcctccggcgaggccaagtgg
ggccagctgtcggacgtcgtgctgctgctgccgcacggccacgaaggccagggcccggac
cacacctccggccgcatcgagcgcttcctctcgctgtgcgcggaaggctcgatgaccgtc
gcggtgccgtcgaccccggcgaactacttccacctcctccgccgtcacgcgctcgacgga
gtcaaccgcccgctggtggtcttcacccccaagtcgatgctgcgcaacaaggcggcgact
tcggcggtcgaggacttcaccggccagtcgaagttcatgtcggtcatcgacgacgccgtc
gtcgacccgtcgaaggtgcgcaaggtcctgctgacgtcgggcaagctgtactgggaactg
gtggccgagcggacgaagcgcgaggcgaacgacatcgcgatcgtgcgcgtcgagcagtac
tacccgctgccgaagaagaagctggtggcggcgctcgagcgctacaacggcgcgcccgcg
gtctgggtccaggaggagccggagaaccagggtgcgtggccgttcttcggcctgaacctg
ccgcggaagctcccggaggtgttctccagcctggacgtcgtgtcgcggcgcccgatggcc
gcgccgtcggccggttcgtccaaggtgcacgaggtcgagcagaaggcgctgatcgctcgg
gccttcgactga
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