KEGG   Actinoplanes oblitus: ACTOB_001901
Entry
ACTOB_001901      CDS       T09687                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
aou  Actinoplanes oblitus
Pathway
aou00270  Cysteine and methionine metabolism
aou00450  Selenocompound metabolism
aou00670  One carbon pool by folate
aou01100  Metabolic pathways
aou01110  Biosynthesis of secondary metabolites
aou01230  Biosynthesis of amino acids
aou04980  Cobalamin transport and metabolism
aou04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:aou00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    ACTOB_001901 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    ACTOB_001901 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    ACTOB_001901 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    ACTOB_001901 (metH)
   04980 Cobalamin transport and metabolism
    ACTOB_001901 (metH)
Enzymes [BR:aou01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     ACTOB_001901 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: WIM98304
LinkDB
Position
2069696..2073280
AA seq 1194 aa
MTETVTKLRDLLAERVLVLDGAWGTMLQGAKLTPADYRGELIPADHPQDVTGDPDLLILT
RPDVILDVHRQYLAAGADITTTNTFTATSIAQADYGLEHLVREMNIQGARLARQAADEFG
GRFVAGSVGPLNVTLSLSPRVDEPAYRAVTFDQVKAAYAEQIAALAEGGVDLLLIETIFD
TLNAKAAIAAAKEVAPHLPLWISVTIVDLSGRTLSGQTVEAFWRSIERAHPLVVGVNCAL
GATEARPHVAELARLSDTFVAAHPNAGLPNAFGGYDETPAQTARLIGEYADSGLVNIVGG
CCGTTPPHIAAIAEAVRGAAPRRIDPPAPTTRFSGLEPFAIGPDTGFVMIGERTNVTGSA
KFRRLIEADDYQAAVDVALDQVRGGANLLDVNMDADLLDSERAMTTFLNLIATEPEVARI
PIMIDSSKWNVLEAGLKCVQGKGVVNSISLKEGPAAFLEQARKIRSFGAGVVVMAFDEQG
QADTTERKVAICGRAYDLLVEDGFDPTDIIFDPNVLAVATGIAEHNGYAKAFIEALPLIK
QRCPGARTSGGISNLSFAFRGNDIVREAMHSAFLFHAVRAGLDMGIVNAGQLAVYQDIPA
DLLELVEDVLFDRRPDATDRLVTFASTVTGSAAKREVDLSWREAPVEERLSYALVHGIVD
FIEADTEEARQKLPRPLDVIEGPLMDGMGVVGDLFGSGKMFLPQVVKSARVMKRSVAYLL
PYMEKDKAEGARGQGKVVLATVKGDVHDIGKNIVGVVLGCNNYEVIDLGVMVPTAKILDT
AIAEGADAIGLSGLITPSLDEMVAVGAEMQRRGLTLPLLIGGATTSKQHTAVRIAPAYDG
PTVHVLDASRVVGVVSDLLDAERAVKLDDANRAEQQRLREQHEKRHAQPLLTLEQARANR
ETVDFAELPTPAFTGVREVQPTIAELREMIDWQFLFLAWELKGKYPAILKEPVARELFDD
ANAMLDQIIADGSFQARGLYGFWPAHRQGDDIVLANGHRLPMLRQQTEKPAGRANRCLAD
YIAPAGDHLGGFAVAIHGAEKLATRFEAEHDDYKAIMVKALADRLAEAFAEYLHLKARRD
WFEPDARPKLEDLHAERFRGIRPALGYPACPDHSEKKDLFQLLDTGRIGVGLTESFAMTP
AAAVSGLIFAHPEAKYFTVGRLGKDQVEDYAARRGVPVAEVERWLRPNLAYSID
NT seq 3585 nt   +upstreamnt  +downstreamnt
gtgactgagaccgtcaccaagctgcgcgacctgctcgccgagcgggtcctcgtcctcgac
ggggcctggggcacgatgctgcagggcgccaagctgaccccggccgactaccgtggcgag
ctcatccccgccgatcacccgcaggacgtcaccggcgaccccgacctgctgatcctcacc
cggccggacgtgatcctcgacgtccaccggcagtacctggcggccggcgccgacatcacc
acgaccaacacgttcaccgctaccagcatcgcccaggccgactacggcctggagcacctg
gtgcgggagatgaacatccagggtgcccggctcgcccggcaggccgccgacgagttcggc
ggccggttcgtggccggctcggtcggcccgctgaacgtgacgctctcgctctcgccccgg
gtcgacgagccggcctaccgtgcggtcaccttcgaccaggtcaaggcggcgtacgcggag
cagatcgcggccctcgccgagggtggcgtcgacctgctgctgatcgagacgatcttcgac
acgctgaacgcgaaggcggcgatcgcggcggccaaggaggtcgccccgcacctcccgctg
tggatctcggtgaccatcgtcgacctctccggccggaccctgtccgggcagaccgtggag
gccttctggcgctcgatcgagcgggcgcacccgctggtggtcggcgtgaactgcgcactc
ggcgcgaccgaggcccgcccgcacgtggcggaactggcccggctgtcggacaccttcgtc
gccgcccacccgaacgcgggcctgccgaacgccttcggcggctacgacgagaccccggcg
cagaccgcccggctgatcggcgagtacgccgactccggcctggtcaacatcgtcggcggc
tgctgcggcaccacgccgccgcacatcgccgcgatcgccgaggcggtgcgcggcgcggcc
ccgcggcggatcgacccgccggcgccgaccacccggttcagcggcctggagccgttcgcg
atcggcccggacaccggcttcgtgatgatcggcgagcggaccaacgtgaccggctcggcc
aagttccgccggttgatcgaggccgacgactaccaggccgccgtcgacgtggcgctggac
caggtccgtggcggcgccaacctgctcgacgtgaacatggacgccgacctgctggacagc
gagcgggcgatgaccacgttcctcaacctgatcgcgaccgagccggaggtggcccggatc
ccgatcatgatcgacagctcgaagtggaacgtgctggaggccggcctcaagtgcgtgcag
ggcaagggcgtggtcaactcgatcagcctgaaggaggggcccgcggcgttcctggagcag
gcccgcaagatccgctcgttcggcgccggtgtggtggtgatggccttcgacgaacagggc
caggccgacaccaccgagcgcaaggtcgccatctgcgggcgagcgtatgacctgctggtc
gaggacggcttcgacccgaccgacatcatcttcgacccgaacgtgctggccgtcgccacc
ggcatcgccgagcacaacggctacgccaaggcgttcatcgaggcgctgccgctgatcaag
cagcgctgcccgggtgcccggaccagcggcggcatctccaacctgtccttcgccttccgg
ggcaacgacatcgtccgcgaggcgatgcactcggcgttcctgttccacgccgtccgggcc
ggcctggacatgggcatcgtcaacgccggtcagctcgccgtctaccaggacatcccggcc
gacctgctggagctggtcgaggacgtgctcttcgaccgccggccggacgccaccgaccgg
ctggtcaccttcgcctccacggtcaccggcagcgccgccaagcgtgaggtcgacctgtcc
tggcgggaggcgccggtcgaggagcgtctgtcgtacgccctggtgcacggcatcgtcgac
ttcatcgaggcggacaccgaggaggcccggcagaaactgccccggccgctcgacgtgatc
gagggcccgctgatggacggcatgggcgtggtcggcgacctgttcggctccggcaagatg
ttcctgccccaggtggtcaagagcgcccgggtgatgaagcggtcggtcgcctacctgctg
ccgtacatggagaaggacaaggccgagggtgcccgcggtcagggcaaggtggtgctcgcc
acggtcaagggcgacgtccacgacatcggcaagaacatcgtcggcgtggtgctcggctgc
aacaactacgaggtgatcgacctcggcgtgatggtgccgaccgcgaagatcctggacacc
gcgatcgccgagggcgccgacgcgatcggcctgtccggcctgatcaccccgtcgctggac
gagatggtcgcggtcggcgccgagatgcagcgccgcgggctcaccctgccgctgctgatc
ggtggcgccaccacgtccaagcagcacaccgcggtgcgcatcgcgccggcgtacgacggg
cccaccgtccacgtcctggacgcgtcccgggtcgtcggcgtcgtctccgacctgctcgac
gccgagcgcgcggtgaagctcgacgacgccaaccgcgccgagcagcagcgcctgcgcgag
cagcacgagaaacggcacgcccagccgctgctcaccctcgagcaggcccgggccaaccgg
gagaccgtcgacttcgccgagctgcccacgcccgccttcaccggtgtccgtgaggtccag
ccgaccatcgccgagctgcgcgagatgatcgactggcagttcctcttcctggcctgggag
ctgaagggcaagtacccggcgatcctgaaggagccggtcgccagggagctcttcgacgac
gccaacgcgatgctcgaccagatcatcgcggacggttcgttccaggcgcgcggcctctac
ggcttctggcccgcgcaccgccagggcgacgacatcgtgctggcgaacgggcaccgcctc
ccgatgctgcgccagcagaccgagaaaccggccggccgcgccaaccgctgcctcgccgac
tacatcgcgccggccggcgaccacctcggcggtttcgcggtggccatccacggcgccgag
aagctggcgacgaggttcgaggccgagcacgacgactacaaggccatcatggtcaaggct
ctggccgaccggctggccgaggcgttcgccgagtacctgcacctcaaggcccgccgcgac
tggttcgagccggacgcccggcccaagctggaggatctgcacgccgagcggttccgcggc
atccgcccggccctgggctaccccgcctgcccggaccacagcgagaagaaggacctcttc
cagctgctcgacaccggccggatcggcgtcggcctgaccgagtcgttcgcgatgaccccg
gccgccgccgtcagcgggctgatcttcgcgcacccggaggcgaagtacttcaccgtcggc
cggttgggtaaggatcaggtggaggactacgccgcccggcgcggcgtgccggtcgccgag
gtggaacgctggctgcgaccgaacctggcgtactcgatcgactga

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