Actinobacillus pleuropneumoniae AP76 (serotype 7): APP7_0834
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Entry
APP7_0834 CDS
T00717
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
apa
Actinobacillus pleuropneumoniae AP76 (serotype 7)
Pathway
apa00010
Glycolysis / Gluconeogenesis
apa00020
Citrate cycle (TCA cycle)
apa00620
Pyruvate metabolism
apa00785
Lipoic acid metabolism
apa01100
Metabolic pathways
apa01110
Biosynthesis of secondary metabolites
apa01120
Microbial metabolism in diverse environments
apa01200
Carbon metabolism
apa01210
2-Oxocarboxylic acid metabolism
Module
apa_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
apa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
APP7_0834 (aceE)
00020 Citrate cycle (TCA cycle)
APP7_0834 (aceE)
00620 Pyruvate metabolism
APP7_0834 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
APP7_0834 (aceE)
Enzymes [BR:
apa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
APP7_0834 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ACE61486
UniProt:
B3GXM7
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Position
complement(928358..930838)
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AA seq
826 aa
AA seq
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MNTIPVSAQPAYPGDHKIERRIRSAVRWNAIAMVLRSQKKDLDLGGHISTFQSAATMYEV
CYNHFFKAATEKNGGDLVFFQGHAAPGMYARAYVEGRLTEEQLDNFRQEAFTDGLSSYPH
PKLMPEFWQFSTVSMGLGPVNAIYQARFLKYLENRGLKDTADQKVYAFLGDGEMDEIESK
GALTFAAREKLDNLIFTVSCNLQRLDGPVNGNGKIIQELEGLFTGAGWEVIKVLWGGNWD
KLFAKDTSGKLAQLMMEVVDGDYLTFKSKDGAYIREHFFGRYPETAALVADMTDDEIWDL
RRGAHDSEKLYAAYAKAQKSDKPVVILAHQVKGYKIPEAESKNTAHQSKKMSLENLKGFR
DYFELPLTDEQVESLEYIKFAEGSEEYNYIHGHRKALNGYVPARRAKFDVEYKVPALDEF
KALLAEQPRGISTTMAFTRALNILLKDKNIGKTIVPMIVDEARTFGMEGLFRQVGIYNPH
GQNYTPSDRDLVAYYREAKDGQVLQEGINELGGAASWVAAATSYSVSNQPMIPFFIYYSM
FGFQRVGDMMWLAGDQLARGFMVGGTSGRTTLNGEGLQHEDGHSHIQAGIIPNCVTYDPS
FAFEVAVIMQDGINRMYGEKQENVFYYMTTLNEVMEQPAMPEGAEEGIRKGLYKFETVKG
KGKGHVQLLGSGSIMRHVREAAQILANDYGVTSDVFSAPSFNELAREGNDAVRWNLLHPT
AEQRIPYVAQVLADLPTVASTDYVKQYADQIRAFVPSKHYHVLGTDGFGRSDSRANLREH
FEVDARYVVIAALSQLAKEGTVETKVVADAIAKFGLNVDRINPLYA
NT seq
2481 nt
NT seq
+upstream
nt +downstream
nt
gtgaatactatccctgtaagcgcacaacctgcatatcccggcgatcataaaattgaacgt
cgtatccgttctgcagtacgttggaatgctattgcaatggttttacgtagccagaagaaa
gatctcgacttaggtggtcatatttctactttccaatcagcggcaacgatgtatgaagtg
tgctataaccacttcttcaaagcggcgactgaaaaaaatggcggcgacttagtatttttc
caaggtcacgccgcgccgggtatgtatgctcgtgcttatgttgaaggtcgtttaacggaa
gagcaattagataacttccgtcaagaagcgtttaccgacggtttatcttcatatcctcac
ccgaaattaatgcccgaattttggcaattctcaaccgtatcaatgggtttaggtcccgtt
aatgcgatttaccaagcgcgtttcttaaaatatcttgaaaaccgcggtttaaaagatacc
gctgatcaaaaagtatatgcgttcttaggcgacggcgagatggatgaaatcgagtctaaa
ggtgcattaactttcgcagcgcgtgaaaaattagataacttaattttcacagtaagctgt
aacttacaacgtttagacggtccggtaaacggtaacggtaaaatcattcaagaattagaa
ggtttatttaccggtgcgggctgggaagtaattaaagtattatggggcggtaactgggat
aaattattcgcaaaagatacctctggtaaattagcgcaattaatgatggaagtggttgat
ggcgactacttaaccttcaaatcgaaagacggtgcttatatccgtgaacacttcttcggt
cgttaccctgaaacagccgcattagttgcggatatgaccgatgatgagatttgggatctt
cgccgtggtgcgcacgacagtgaaaaactttatgccgcatatgcgaaagcacaaaaatca
gacaaaccggttgtgattttagcgcaccaagttaaaggttataaaattcctgaagcggaa
agtaaaaataccgctcaccaatcgaaaaaaatgtcattagaaaacttaaaaggcttccgt
gactacttcgaattaccattgacggatgaacaagtagaaagcttagagtacatcaagttt
gccgaaggttctgaagaatacaactacattcacggtcaccgtaaagcattaaacggttat
gtgccggctcgtcgtgccaaattcgacgtagagtataaagtccctgcattagatgaattt
aaagcattacttgcagaacaaccacgtggtatttcaaccacaatggcgtttacacgtgca
ttaaatatcttattaaaagataaaaatatcggtaaaaccatcgttccgatgatcgtggac
gaagcgcgtacattcggtatggaaggtttattccgtcaagtgggtatttacaacccgcac
ggtcaaaactataccccttcagaccgtgatttagtggcttactaccgtgaagcgaaagac
ggtcaagtattacaagaaggtatcaacgaattaggtggtgcggcatcttgggtggctgcg
gcgacttcttactccgtaagtaaccaaccgatgatcccgttcttcatctattactcaatg
ttcggtttccaacgtgtgggcgatatgatgtggttggcaggtgaccaattagcgcgcggt
ttcatggttggcggtacttcaggtcgtacaactttaaacggtgaaggcttacaacacgaa
gacggtcacagccatatccaagcgggtattattcctaactgtgtaacttatgatccatca
tttgcgtttgaagtagcggtaattatgcaagacggtattaaccgtatgtatggtgaaaaa
caagaaaatgttttctactatatgacaacattaaacgaagtaatggagcagcctgcaatg
cctgaaggtgcagaagagggtatccgtaaaggtttatataaatttgaaacggttaaaggt
aaaggtaaaggtcacgttcagttattaggttcaggttctattatgcgtcacgttcgtgaa
gcagcacagatccttgcgaatgactacggcgtaacttcagatgtattctcagctccgtca
tttaacgagctagctcgtgaaggtaacgatgcagtacgttggaacttattacacccgaca
gcagaacaacgcattccttatgtagcgcaagtattagcggacttaccgacagtcgcttca
accgactatgtaaaacaatatgcggatcaaattcgtgcattcgtaccaagcaaacactat
cacgtgttaggtacggacggtttcggtcgttcggacagccgtgcgaacttacgtgagcat
ttcgaagtagatgcgcgttatgttgttattgcagcattatcacaattagcgaaagaaggc
acggtagaaacgaaagttgttgctgatgcaatcgctaaattcggcttaaacgtagatcgt
attaacccgttatacgcataa
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