KEGG   Amycolatopsis sp. FBCC-B4732: MUY14_13030
Entry
MUY14_13030       CDS       T08335                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
aprt  Amycolatopsis sp. FBCC-B4732
Pathway
aprt00270  Cysteine and methionine metabolism
aprt00450  Selenocompound metabolism
aprt00670  One carbon pool by folate
aprt01100  Metabolic pathways
aprt01110  Biosynthesis of secondary metabolites
aprt01230  Biosynthesis of amino acids
aprt04980  Cobalamin transport and metabolism
aprt04981  Folate transport and metabolism
Module
aprt_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:aprt00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    MUY14_13030 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    MUY14_13030 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    MUY14_13030 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    MUY14_13030 (metH)
   04980 Cobalamin transport and metabolism
    MUY14_13030 (metH)
Enzymes [BR:aprt01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     MUY14_13030 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: UOX91497
LinkDB
Position
3047154..3050711
AA seq 1185 aa
MSDRLSSPFLEVLGSRVLVADGAMGTALQAHDLSLDDFGGLEGCNEILNVTRPDVVRSVH
RGYLEAGADAVETNTFGANFANFAEYDITGRIFELAEAGARLAREAADEFATPDRPRFVL
GSVGPGTKLPTLGHAPFTTLRDAYQEQVRGLLAGGVDAVIVETTQDILQTKASIIGAKRA
MAADGRRVPVLASITVETTGTMLLGTEVGAALAALEPLGIDVIGLNCATGPAEMSEHLRQ
LAKHARVPLSVMPNAGLPELGPDGAVYPLGPEALVEALTGFVREFGVGLVGGCCGTTDEH
IRQLAAAVADTAPVPRRPRPEPGVSSLYQAVPFKQDASVLMIGERTNANGSKAFRTAMLE
GRWDDCVEIAREQTRDGAHLLDLCVDYVGRDGTADMAELAGRLATASTLPIMLDSTEVPV
LRAGLQRLGGRGAVNSVNYEDGAGPESRFTKVMELVSEYGAAVVALTIDEEGQARTARKK
ADIATRLIEDITGNWGLRTSDIIVDALTFTIATGQEESRRDGAETIEAIREIKRRHPEVQ
TTLGLSNISFGLNPAARQVLNSVFLHECVQAGLDTAIVHASKILPMARIPDDRRAVALDL
IHDRRREGYDPLQELMALFEGVSAASSKASRAEELAALPLFERLERRIVDGERNGLADDL
DAALEQRPALQIINDTLLSGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAHLEPHMEKED
DDAGKGRIVLATVRGDVHDIGKNLVDIILSNNGYEVVNLGIKQPITTILDAAEEQGADAI
GMSGLLVKSTVIMKENLQEMNSRGVSARWPVLLGGAALTRSYVENDLTELYLGDVRYARD
AFEGLRLMDAIMAAKRGESPLVDTGAEQKRVERKERRERSLRIAEARKARKAEEEALEGP
PPERSDVATDVPLPVPPFWGSRVVKGIALADYAAMLDERATFMGQWGLKGARGGAGPTYD
ELVESEGRPRLRYWLDRLTADGVLATAAVVYGYFPCVAEGDDLVVLTEPEPDAPERLRFT
FPRQRRDRRLCLADFYRPREAGEVDVVPFTVVTMGQPIADYANELFAANAYRDYLEVHGL
GVQLTEALAEYWHCRIRGELTLPGGVAVASDDPDDVEDFFKLGYRGARFSLGYGACPDLE
DRAKIVALLEPGRIGVKLSEEYQLHPEQSTDAIVCHHPEAKYFNT
NT seq 3558 nt   +upstreamnt  +downstreamnt
atgtccgaccgcctgtcgtcgccgtttctcgaagtcctgggctcgcgcgtcctggtggcc
gacggggcgatgggtactgcgctgcaggcccacgacctgagcctggacgacttcggtggg
ctggaaggctgcaacgagatcctcaacgtcacccggccggacgtcgtccggtccgtgcac
cgcggctacctcgaagcgggtgcggacgcggtcgagaccaacactttcggggcgaatttc
gccaacttcgccgaatacgacatcaccggccggatcttcgagctggccgaagccggcgcc
cggctggctcgggaggccgcggacgagttcgcgacgccggatcgcccgcggttcgtgctc
ggctcggtcggccccggcacgaagctcccgacactcggccacgcgccgttcaccaccctg
cgggacgcctaccaggagcaggtccgcggcctgctggccggcggcgtggacgcggtgatc
gtcgagaccacccaggacatcctccagacgaaggcgtcgatcatcggcgcgaagcgggcg
atggccgccgacggccgacgggtgccggtcctcgcttcgatcaccgtcgaaacgaccggg
accatgctgctcggcaccgaggtcggtgcggcactggccgcgctcgagccgctcggcatc
gacgtcatcgggctcaactgcgccaccggcccggccgagatgagcgagcacctgcggcag
ctggccaagcacgcgcgggtgccgctgtcggtgatgcccaacgccggcctgcccgagctc
ggcccggacggcgccgtctacccgctcggcccggaagcgctggtcgaggcgctgaccggg
ttcgtccgcgagttcggcgtcggcctggtcggcggctgctgcgggacgaccgacgagcac
atccggcagctcgcggccgcggtcgcggacaccgcgccggtgccgcggcggccgcggccc
gagcccggcgtgtcgtcgctgtaccaggcggtgccgttcaagcaggacgccagcgtgctg
atgatcggcgagcggaccaacgccaacggctcgaaggcgttccgcaccgcgatgctcgag
ggccgctgggacgactgcgtcgagatcgcccgcgagcagacccgcgacggcgcccacctg
ctcgacctctgcgtcgactacgtcgggcgcgacggcaccgccgacatggccgagctcgcc
gggcggctcgccaccgcgtcgacgctgccgatcatgctcgactccaccgaggtcccggtg
ctgcgcgccgggctgcagcggctcggcggccgcggcgcggtcaactccgtcaactacgag
gacggcgccgggccggagtcgcggttcacgaaggtcatggagctggtcagcgagtacggc
gccgccgtcgtcgccctgaccatcgacgaagaaggccaggcgcggaccgcgcggaagaag
gccgacatcgcgacccggctgatcgaggacatcaccgggaactgggggctgcgcacctcc
gacatcatcgtcgacgccctcacgttcaccatcgccaccggacaggaggaatcgcgccgc
gacggggccgagacgatcgaagcgatccgcgagatcaagcgacgccaccccgaggtccag
accacgctcggcctgtccaacatctccttcgggctcaaccccgccgcgcggcaggtgctg
aactcggtcttcctgcacgagtgcgtacaggcggggctggacaccgcgatcgtgcacgcg
tcgaagatcctcccgatggcgcggatcccggacgaccgccgcgcggtcgccctcgacctg
atccacgaccgccgccgcgagggctacgacccgctgcaggagctgatggccctgttcgag
ggcgtgagcgcggcgtcgtcgaaggcgtcgcgcgccgaggaactggccgcgctgccgctg
ttcgaacgcctggaacgccggatcgtcgacggcgagcgcaacggcctggccgacgacctc
gacgcggcgctggaacagcggcccgccctgcagatcatcaacgacaccctgctgtcgggc
atgaagaccgtcggcgagctgttcgggtccgggcagatgcagctgccgttcgtgctgcag
tccgccgaggtgatgaaggcggccgtcgcgcacctcgagccgcacatggagaaggaggac
gacgacgccggcaaggggcggatcgtgctggccaccgtccgcggcgacgtgcacgacatc
ggcaagaacctcgtcgacatcatcctgtccaacaacggctacgaggtcgtcaacctcggc
atcaagcagccgatcacgaccatcctggacgcggccgaggagcagggcgccgacgcgatc
gggatgtccgggctgctggtgaagtcgaccgtgatcatgaaggagaacctccaggagatg
aactcccggggcgtctccgcgcgctggccggtgctgctcggcggcgccgcgctcacccgg
tcgtacgtggagaacgacctcacggagctctacctcggcgacgtccgctacgcgcgggac
gcgttcgagggcctgcggctgatggacgcgatcatggccgccaagcgcggggaatcgccg
ctggtggacaccggcgccgagcagaagcgcgtggagcgcaaggaacggcgtgagcgctcc
ctgcggatcgccgaagcgcgcaaggcccgcaaagccgaggaggaagcgctcgaaggcccg
ccgccggagcggtcggacgtcgccaccgacgtcccgctgccagtgccgccgttctggggt
tcgcgcgtggtcaagggcatcgcgctcgccgactacgccgcgatgctcgacgaacgcgcg
accttcatggggcagtgggggctcaagggcgcccgcggcggcgccgggccgacgtacgac
gagctcgtcgagtccgaaggacggccgcggctgcggtactggctcgaccggctgaccgcc
gacggcgtcctggccaccgcggccgtcgtctacggctacttcccgtgcgtcgccgagggc
gacgacctggtcgtgctcaccgagcccgagccggacgcgcccgagcggctgcggttcacc
ttcccgcgccagcgccgcgaccggcggctctgtctggccgacttctaccggccgcgggag
gcgggcgaagtcgacgtcgtgccgttcaccgtcgtgaccatgggccagccgatcgcggat
tacgcgaacgagctgttcgccgcgaacgcctaccgcgactacctggaggtgcacggcctc
ggcgtccagctcaccgaggcactggccgagtactggcactgccgcatccggggcgagctg
actctccccggcggtgtggcggtcgcctcagacgaccccgacgacgtcgaggacttcttc
aagctcggctaccgtggagcgaggttctccctgggctatggcgcctgtcccgatctcgag
gaccgggcgaagatcgtcgcgctcctcgagccgggccgcatcggcgtcaagctgtccgag
gagtaccagctgcaccccgagcagtcgaccgacgcgatcgtctgccaccacccggaagcg
aagtacttcaacacctga

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