Amycolatopsis rhabdoformis: VSH64_29065
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Entry
VSH64_29065 CDS
T09694
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
arhd
Amycolatopsis rhabdoformis
Pathway
arhd00020
Citrate cycle (TCA cycle)
arhd00630
Glyoxylate and dicarboxylate metabolism
arhd00785
Lipoic acid metabolism
arhd01100
Metabolic pathways
arhd01110
Biosynthesis of secondary metabolites
arhd01120
Microbial metabolism in diverse environments
arhd01200
Carbon metabolism
arhd01210
2-Oxocarboxylic acid metabolism
Module
arhd_M00009
Citrate cycle (TCA cycle, Krebs cycle)
arhd_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
arhd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
VSH64_29065
00630 Glyoxylate and dicarboxylate metabolism
VSH64_29065
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
VSH64_29065
Enzymes [BR:
arhd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
VSH64_29065
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
VSH64_29065
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
VSH64_29065
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
VSH64_29065
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
DUF7513
Motif
Other DBs
NCBI-ProteinID:
WSE26919
UniProt:
A0ABZ1HYI0
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All DBs
Position
6337033..6340770
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AA seq
1245 aa
AA seq
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MSSSSPASQFGPNEWLVEEMYDQFLADPSSVDAAWHDFFADFKPTQTAQAKADSARQSTA
TPATTGSNGHASEPSPKAVQNAESAARQSAPAKPAAAPAPAPAPKSAPAKSAPAKPATQA
APAAAKEPAAKEEPETKQLRGAAAAIAKNMDASLTVPTATSVRAVPAKLMADNRIVINNH
LKRTRGGKISFTHLIGYAMVRALKSFPNMNRHYQVIDGKPFSVTPEHVNFGLAIDMKGKE
GARTLVVASVKGVEDMSFLQFWQAYEDVIKKARNNKLTADDFAGTTISLTNPGGIGTNHS
VPRLSAGQGAIIGVGAMQYPAAFEGTSEKTLVDLAVSKIMTLTSTYDHRIIQGAESGEYL
KRIHELLLGEDGFYDDVFTSLRLPYEPIRWVADIPEGPVDKTARVIELIDAFRTRGHLMA
DTDPLNYRQRSHVDLDVISHGLTLWDLDREFPVGGFAGQEKMKLRDILGVLRGSYCRTVG
IEYTHILDPEERRWIQERVEIPHEKPDATVQKYVLSKLNAAEAFETFLQTKYVGQKRFSL
EGGETAIPLLDTILDKAAEHELDEVVIGMPHRGRLNVLANIVGKPISQIFQEFEGNLDPG
QAHGSGDVKYHLGAEGKYFRMFGDGETKVSLASNPSHLETVDPVLEGIVRAKQDILDKGG
EGYTVLPVLMHGDAAFAGQGVVAETLNLALLRGYRTGGTVHVIVNNQVGFTTAPEHSRSS
QYATDVAKMIGSPIFHVNGDDPEAAHWVAQLAVEYRQAFHKDVVIDLICYRRRGHNEGDD
PSMTQPAMYDIIDTKRSVRKIYTESLIGRGDISVDEAEAALRDFSSQLEHVFNEVRELEK
HPAKASPSVEEEQQVPAKVTTAVSTEVVERIGDAFLNVPEGFSPHPRVKPVMERRHKMSR
EGDVDWAFGELLAFGSLAMEGRLVRLSGQDSRRGTFTQRHSVFIDRKTGQEYSPLQNLAE
GQGRVMIYDSALSEYAAVGFEYGYAVANPESLVMWEAQFGDFVNGAQTVIDEYISSGEAK
WGQRSDVVLLLPHGHEGQGPDHTSGRIERFLSLCAEGSMTVAVPSTPANYFHLLRRHALD
GIQRPLVVFTPKSMLRNKAATSAVEDFTGQSRFMSVIDDTTQNPDGVRKVLLTSGKLYWE
LVAERNKREAHDVAIVRIEQYYPLPKRKLLAAIERYSNATQIAWVQEEPENQGAWPFFGL
NLPRKFPEVFAGLQVVSRRPMAAPSAGSSKVHEVEQKALIAKAFD
NT seq
3738 nt
NT seq
+upstream
nt +downstream
nt
gtgtccagcagcagccctgcgtcacagttcggccccaacgagtggttggtcgaggaaatg
tacgaccagttcctcgcggacccttcctcagtcgatgccgcctggcacgacttcttcgcg
gacttcaagccgacgcagacggcacaggccaaggccgacagtgcgcgccagagcaccgcc
acccctgccacgaccggcagcaacggccacgcgagcgagccgtcccccaaggcggtccag
aacgccgagtcggcggcccggcagtcggccccggcgaagcccgccgcggcacccgcgccg
gctccggccccgaagagcgcgcccgccaagagcgcgcccgcgaagccggccacgcaggcc
gcgccggccgccgccaaggagccggccgccaaggaagagcccgagacgaagcagctgcgc
ggcgccgcggcggcgatcgcgaagaacatggacgcgtcgctgaccgtcccgaccgccacg
agcgtgcgcgccgtgccggcgaagctgatggcggacaaccgcatcgtcatcaacaaccac
ctcaagcgcacgcggggcggcaagatctcgttcacgcacctcatcggttacgcgatggtg
cgcgcgctgaagtcgttcccgaacatgaaccggcactaccaggtgatcgacggcaagccg
ttctcggtcacgccggagcacgtgaacttcggtctcgccatcgacatgaagggcaaggag
ggtgcgcgcaccctcgtcgtggcctcggtcaagggcgtcgaagacatgtccttcctgcag
ttctggcaggcgtatgaggacgtgatcaagaaggcccgcaacaacaagctcaccgcggac
gacttcgccggcaccaccatctcgctgaccaacccgggcggcatcggcaccaaccactcg
gtgccgcgcctgtcggccggccagggcgcgatcatcggcgtcggtgcgatgcagtacccg
gcggcgttcgagggcacgagcgagaagacgctggtcgacctcgccgtcagcaagatcatg
acgctcacctcgacgtacgaccaccgcatcatccagggcgcggagtcgggcgagtacctc
aagcgcatccacgagctgctgctcggcgaagacggcttctacgacgacgtcttcaccagc
ctgcgcctgccgtacgagccgatccgctgggtcgccgacatccccgagggcccggtcgac
aagaccgcccgcgtgatcgagctgatcgacgcgttccgcacgcgcggtcacctcatggcc
gacacggacccgctgaactaccgccagcgcagccacgtcgacctcgacgtgatctcccac
ggcctcaccctgtgggacctcgaccgcgagttcccggtcggcggcttcgccggccaggag
aagatgaagctgcgcgacatcctgggcgtgctgcgcggctcgtactgccgcaccgtcggc
atcgagtacacgcacatcctcgaccccgaggaacgccgctggatccaggagcgcgtggag
atcccgcacgagaagccggacgccacggtccagaagtacgtgctctcgaagctcaacgcc
gccgaggcgttcgagaccttcctgcagacgaagtacgtgggccagaagcgcttctcgctg
gaaggcggcgagacggcgatcccgctgctcgacaccatcctcgacaaggccgccgagcac
gagctcgacgaggtcgtgatcggcatgccgcaccgcggccgcctcaacgtgctggccaac
atcgtcggcaagccgatcagccagatcttccaggagttcgagggcaacctcgacccgggc
caggcccacggttccggcgacgtgaagtaccacctcggcgccgagggcaagtacttccgc
atgttcggcgacggcgagacgaaggtgtcactggcctcgaacccgtcgcacctcgagacg
gtggacccggtgctcgagggcatcgtgcgcgccaagcaggacatcctcgacaagggcggc
gagggctacaccgtgctgccggtgctgatgcacggcgacgcggccttcgcgggccagggt
gtggtggccgagacgctgaacctggcgctgctgcgcgggtaccgcaccggcggcaccgtg
cacgtgatcgtgaacaaccaggtcggcttcaccaccgcgccggagcactcgcgctcctcg
cagtacgccaccgacgtcgcgaagatgatcggctcgccgatcttccacgtgaacggcgac
gaccccgaagccgcccactgggtggcccagctggccgtggagtaccgccaggcgttccac
aaggacgtggtcatcgacctcatctgctaccgccgccgcggccacaacgagggcgacgac
ccctcgatgacgcagccggcgatgtacgacatcatcgacaccaagcgctcggtccggaag
atctacaccgagtcgctgatcggccgcggggacatctccgtggacgaggccgaggccgcg
ctgcgcgacttctcgagccagctcgagcacgtgttcaacgaggtgcgcgagctcgagaag
cacccggcgaaggcgagcccctcggtcgaggaagagcagcaggtgccggcgaaggtcacc
acggccgtctccaccgaggtcgtggagcgcatcggcgacgcgttcctcaacgtgcccgag
ggcttcagcccccacccgcgcgtgaagccggtgatggagcggcgccacaagatgtcgcgc
gaaggcgacgtcgactgggccttcggcgagctgctcgcgttcggttcgctggcgatggag
ggccgcctggtgcggctgtccggccaggactcgcgccgcggcacgttcacgcagcggcac
tcggtgttcatcgaccgcaagaccggccaggagtactcgccgctgcagaacctggccgag
ggccagggccgcgtgatgatctacgactcggcgctgtcggagtacgcggccgtcggcttc
gagtacggctacgcggtcgccaaccccgagtcgctcgtgatgtgggaagcgcagttcggt
gacttcgtcaacggcgcgcagaccgtgatcgacgagtacatctcctcgggcgaggccaag
tggggccagcgctccgacgtcgtgctgctgctgccgcacggccacgagggccagggcccg
gaccacacgtcgggccgcatcgagcgcttcctctcgctgtgcgccgagggctcgatgacc
gtcgccgtgccgtcgacgccggcgaactacttccacttgctgcgccgccacgctctcgac
ggcatccagcgcccgctggtggtcttcacgccgaagtcgatgctgcgcaacaaggccgcg
acgtcggcggtcgaggacttcaccgggcagagccgcttcatgtccgtgatcgacgacacc
acccagaaccccgacggcgtccgcaaggtgctgctgacctcgggcaagctctactgggag
ctcgtggccgagcgcaacaagcgcgaagcccacgacgtcgcgatcgtgcgcatcgagcag
tactacccgctgccgaagcgcaagctgctggccgccatcgagcgctacagcaacgcgacg
cagatcgcgtgggtccaggaagagccggagaaccagggtgcgtggccgttcttcggcctc
aacctgccgcggaagttcccggaggtcttcgcgggcctgcaggtcgtgtcgcgtcgcccg
atggccgcgccgtcggccggttcgtcgaaggtgcacgaggtcgagcagaaggcgctgatc
gcgaaggcgttcgactga
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