Amycolatopsis roodepoortensis: NQK81_32195
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Entry
NQK81_32195 CDS
T08507
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
aroo
Amycolatopsis roodepoortensis
Pathway
aroo00020
Citrate cycle (TCA cycle)
aroo00630
Glyoxylate and dicarboxylate metabolism
aroo00785
Lipoic acid metabolism
aroo01100
Metabolic pathways
aroo01110
Biosynthesis of secondary metabolites
aroo01120
Microbial metabolism in diverse environments
aroo01200
Carbon metabolism
aroo01210
2-Oxocarboxylic acid metabolism
Module
aroo_M00009
Citrate cycle (TCA cycle, Krebs cycle)
aroo_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
aroo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
NQK81_32195
00630 Glyoxylate and dicarboxylate metabolism
NQK81_32195
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NQK81_32195
Enzymes [BR:
aroo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
NQK81_32195
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
NQK81_32195
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
NQK81_32195
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
NQK81_32195
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
UUV29402
LinkDB
All DBs
Position
complement(6716286..6720029)
Genome browser
AA seq
1247 aa
AA seq
DB search
MSSSSPASQFGPNEWVVEEMYDQFLADPSSVDAAWHDFFADFKPTQDAQAKADDARQNSG
EPGNEGPGANGQAAAQPSPQTVRNAESTAKQTAPKNAPAKAAPKTEAKAAAPKAAPKADP
KPAEKAPAKPAEKDAEPESKQLRGAAAAIAKNMDASLSVPTATSVRAVPAKLMADNRIVI
NNHLKRTRGGKISFTHLIGYAMVRALKNFPNMNRHYQLIDGKPFAVTPEHVNFGLAIDMK
GKEGARTLVVASIKATENMTFMQFWQAYEEIVKKARNGKLTADDFAGTTISLTNPGGIGT
NHSVPRLQAGQGAIIGVGAMQYPAHFEGTSEKALVDLGVSKIMTLTSTYDHRIIQGAESG
EFLKRIHELLLGEDGFYDDVFTSLRLPYEPIRWVADIPDGPVDKTARVIELIDAFRMRGH
LMADTDPLNYRQRSHADLDVLSHGLTLWDLDREFPVGGFAGQERMKLRDILGVLRNSYCR
TVGIEYTHILDPEERRWIQDRVEIPHEKPDPAVQKYVLSKLNAAEAFETFLQTKYVGQKR
FSLEGGETAIPLLDTLLDKAAEHELDEVVIGMPHRGRLNVLANIVGKPIAQIFQEFEGNL
DPGQAHGSGDVKYHLGAEGKYFRMFGDGETKVSLTANPSHLETVDPVLEGIVRAKQDILD
KGGEGFTVLPVLMHGDAAFAGQGVVAETLNLALLRGYRTGGTVHVIVNNQVGFTTAPEHS
RSSQYATDVAKMIGSPIFHVNGDDPEAAHWVAKLAVDYRQAFHKDVVIDLICYRRRGHNE
GDDPSMTQPAMYDIIDTKRSVRKTYTESLIGRGDISVEEAEAALRDFSSQLEHVFNEVRE
LEKHPAKASPSVEEEQQVPAKVPTATTTEVIEHIGDAFLNVPEGFTPHPRVKPVMERRHK
MSREGGIDWAFGELLAFGSLAMEGRLVRLSGQDSRRGTFTQRHSVLIDRKTGQEYSPLQN
LAEGQGRVMIYDSALSEYAAVGFEYGYSVANSEALVMWEAQFGDFVNGAQTVIDEYISSG
EAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLSLCAEGSMTVAVPSTPANYFHLLRRH
ALDGVNRPLVVFTPKSMLRNKAATSAVEDFTGQSKFMSVIDDVDVDPSKVRKVLLTSGKL
YWELVAERTKREANDIAIVRVEQYYPLPKKKLLAALERYNGAPAVWVQEEPENQGAWPFF
GLNLPRKLPEVFSSLDVVSRRPMAAPSAGSSKVHEVEQKALIARAFD
NT seq
3744 nt
NT seq
+upstream
nt +downstream
nt
gtgtccagcagcagccctgcgtcacaattcggccccaacgagtgggtcgtcgaggaaatg
tacgaccagttccttgccgaccccagctcagtcgatgccgcctggcacgacttcttcgcg
gacttcaagccaacgcaggacgcgcaggcgaaggctgacgacgcacgtcagaactccgga
gagcccggcaacgagggtcccggcgccaacggccaggccgccgcccagccgtcgcctcag
acagtccgcaacgccgagtccaccgcgaagcagaccgctccgaagaacgcccccgcgaag
gccgccccgaagaccgaggcgaaggcggcggcgcccaaagccgcgcccaaggccgacccc
aagccggctgagaaggcccccgccaagcccgccgagaaggacgccgagccggagtcgaag
cagctccgcggcgccgcggcggcgatcgcgaagaacatggacgcctcgctgtccgtgccg
acggccacgagcgtgcgcgccgtcccggcgaagctgatggccgacaaccgcatcgtcatc
aacaaccacctcaagcgcacgcgcggcggcaagatctccttcacgcacctcatcgggtac
gcgatggtccgcgcgctgaagaacttcccgaacatgaaccggcactaccagctgatcgac
gggaagccgttcgcggtcacgccggagcacgtgaacttcggtctcgcgatcgacatgaag
ggcaaggaaggcgcccgcacgctcgtcgtggcctccatcaaggccaccgagaacatgacc
ttcatgcagttctggcaggcctacgaggagatcgtcaagaaggcccgcaacggcaagctg
accgccgacgacttcgccggcaccacgatctcgctgaccaaccccggcggcatcggcacc
aaccactcggtgccgcgcctgcaggcgggccagggcgcgatcatcggcgtcggcgccatg
cagtacccggcgcacttcgagggcaccagcgagaaggccctggtcgacctcggcgtctcc
aagatcatgacgctgacctcgacctacgaccaccgcatcatccagggcgcggagtcgggc
gagttcctcaagcgcatccacgagctgctgctcggcgaggacggcttctacgacgacgtc
ttcaccagcctgcgcctgccctacgagccgatccgctgggtcgccgacatcccggacggc
ccggtcgacaagaccgcgcgcgtgatcgagctgatcgacgccttccgcatgcgcggtcac
ctgatggccgacaccgacccgctgaactaccggcagcgcagccacgccgacctcgacgtc
ctctcccacggcttgaccctgtgggacctggaccgcgagttcccggtcggcggcttcgcc
ggccaggagcggatgaagctgcgcgacatcctcggcgtcctgcgcaactcgtactgccgc
accgtcggcatcgagtacacgcacatcctcgaccccgaggagcgccgctggatccaggac
cgcgtcgagatcccgcacgagaagccggaccccgccgtccagaagtacgtgctctcgaag
ctcaacgccgccgaggcgttcgagaccttcctgcagaccaagtacgtcggccagaagcgg
ttctccctcgaaggcggcgagacggcgatcccgctgctcgacacgctgctggacaaggcc
gccgagcacgagctcgacgaggtcgtcatcggcatgccgcaccgcggccgcctgaacgtg
ctcgcgaacatcgtcggcaagccgatcgcgcagatcttccaggagttcgagggcaacctc
gacccgggccaggcgcacggttccggtgacgtgaagtaccacctcggcgccgagggcaag
tacttccgcatgttcggcgacggcgagaccaaggtgtcgctgaccgcgaacccgtcgcac
ctggagaccgtcgacccggtcctcgagggcatcgtccgcgcgaagcaggacatcctcgac
aagggtggcgagggcttcaccgtcctccccgtcctgatgcacggcgacgcggccttcgcg
ggccagggtgtcgtggccgaaaccctgaacctggcgctgctgcgcgggtaccgcaccggc
ggcaccgtgcacgtcatcgtcaacaaccaggtcggcttcaccaccgcgcccgagcactcg
cggtcgagccagtacgccaccgacgtcgcgaagatgatcggctccccgatcttccacgtg
aacggcgacgaccccgaggccgcgcactgggtggccaagctggccgtcgactaccgccag
gcgttccacaaggacgtcgtgatcgacctgatctgctaccgccgccgcggccacaacgag
ggcgacgacccctcgatgacgcagccggcgatgtacgacatcatcgacacgaagcgttcg
gtccggaagacctacaccgaatcgctgatcggccgcggcgacatctccgtcgaagaggcc
gaagccgcgttgcgcgacttctccagccagctggagcacgtgttcaacgaggtccgcgag
ctggagaagcacccggcgaaggccagcccctcggtcgaggaggagcagcaggtcccggcg
aaggtgcccacggcgaccaccaccgaggtcatcgagcacatcggcgacgccttcctcaac
gtgcccgagggcttcaccccgcacccgcgggtcaagccggtcatggagcgccgccacaag
atgtcccgcgaaggcggcatcgactgggcgttcggtgagctgctcgccttcggttcgctg
gccatggagggccgcctggtgcggctgtccggccaggactcccgccgcggcacgttcacc
cagcgccactcggtgctgatcgaccgcaagaccggccaggagtactcgccgctgcagaac
ctggccgagggccagggccgcgtgatgatctacgactcggcgctgtcggagtacgcggcg
gtcggcttcgaatacggctactccgtggccaactccgaagcgctggtcatgtgggaagcg
cagttcggtgacttcgtcaacggcgcgcagaccgtcatcgacgagtacatctcctccggc
gaggccaagtggggccagctctccgacgtcgtgctgctgctgccgcacggccacgagggc
cagggcccggaccacacctccggccgcatcgagcgtttcctctcgctgtgcgcggagggc
tcgatgaccgtcgcggtcccgtcgaccccggcgaactacttccacctgctccgccgtcac
gcgctcgacggagtcaaccggccgctcgtggtcttcacccccaagtcgatgctgcgcaac
aaggcggcgacctcggcggtcgaggacttcaccggccagtcgaagttcatgtcggtcatc
gacgacgtcgatgtcgacccgtcgaaggtgcgcaaggtcctgctgacctcgggcaagctg
tactgggagctggtggccgagcgcaccaagcgcgaggcgaacgacatcgcgatcgtgcgg
gtcgagcagtactacccgctgccgaagaagaagctgctggcggcgctcgagcgctacaac
ggcgctcccgcggtctgggtccaggaggagccggagaaccagggtgcgtggccgttcttc
ggcctgaacctgccgcggaagctcccggaggtgttctccagcctggacgtcgtgtcgcgt
cgtccgatggcggcgccgtcggccggttcgtccaaggtgcacgaggtcgagcagaaggcg
ctgatcgcgcgggccttcgactga
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