KEGG   Actinocatenispora sera: Asera_43220
Entry
Asera_43220       CDS       T07446                                 
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine methyltransferase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
aser  Actinocatenispora sera
Pathway
aser00270  Cysteine and methionine metabolism
aser00450  Selenocompound metabolism
aser00670  One carbon pool by folate
aser01100  Metabolic pathways
aser01110  Biosynthesis of secondary metabolites
aser01230  Biosynthesis of amino acids
aser04980  Cobalamin transport and metabolism
aser04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:aser00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Asera_43220 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Asera_43220 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Asera_43220 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Asera_43220 (metH)
   04980 Cobalamin transport and metabolism
    Asera_43220 (metH)
Enzymes [BR:aser01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Asera_43220 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding CM_2 DUF3197 GlnR_1st
Other DBs
NCBI-ProteinID: BCJ30214
UniProt: A0A810L413
LinkDB
Position
4515839..4519360
AA seq 1173 aa
MANAKLLDIVRDRVLLADGGMGTMLQAADPTLDDFQGHEGCNEILNVTRPEVVRGIHDAY
FAAGSDCVETNTFGANFGNLGEYGIVERTTELAEAGARLAREVADGWSSPDRPRFVLGSM
GPGTKLPTLGHAPFATLRDSYQQAAAGLITGGADALIVETCQDLLQAKSAVIGAKRAMAA
AGVTVPLICHVTVETTGTMLVGSEIGAALTALEPLGVDFIGLNCATGPAEMAEHLRYLSQ
HARVRLSVMPNAGLPELTPDGARYPLTPDELAAALDEFVSDYGASLVGGCCGTTPEHIAR
VAERVAGTTPASRTPSTEPGVSSMYHHVPFRQDAGVLMIAERTNANGSKVFRDKMLAGDF
AGCVEIARDQARSGSHLLDLCIDYVGRDGSVDMREIAGRFATASTLPIMLDSTEPAVIEA
GLETLGGRCVVNSVNYEDGDGPESRFARAMPIIREHGAAVVALTIDEEGQARTAEWKERV
AVRMIEDLTGNWGLSTADILVDCLTFPVSTGQEETRRDALETIEAIRRIHARYPEVNFTL
GVSNVSFGLNPAARQVLNSVFLHECVQAGLSSAIVHASKILPMSKIPDDQREVALDLVYD
RRREGYDPLQKLIEMFEGVDAASARASRAEELAALPLVERLKRRIIDGERNGLDDDLAAA
LAEGYRALDIVNDILLDGMKVVGDLFGSGQMQLPFVLQSAEVMKAAVAYLEPHMEATDEA
GKGTIVLATVKGDVHDIGKNLVDIILSNNGYTVVNIGIKQPIAAILEAAEQHQADVIGMS
GLLVKSTVVMKDNLAEMMARGLHSRWPVMLGGAALTRAYVEDDLRGQFEGDVHYAKDAFE
GLSLMDKVMAARRGGAPVIDPEREAQLAKRRERRARQQSMVADTAPDLYDASVRSDVATD
VDVPRPPFFGTRVAKGIPLNDYAAMLDERATFLGQWGLKPTRGGDGPSYEELAESEGRPR
LRYWLERLATDKLIEAAVVYGYFPCYSEGNDLVVLDENGHSERARFTLPRQRRDRRLCIA
DFFRPKESGELDVVAFQLVTVGPAISDYTAKLFADNAYRDYLEVHGLSVQLAEALAEYWH
RRIRTELVLPGGTTVADSDPGDLAGMLKTEFRGCRYAFGYSACPDLEERAKVVSLLDPDR
INVSLSEEYQLSPEQSTDALVVHHPEASYFNAR
NT seq 3522 nt   +upstreamnt  +downstreamnt
gtggcaaacgcgaagctgttggacatcgtccgtgaccgggtgctgctcgccgacggcggg
atgggcaccatgctgcaggccgccgaccccaccttggacgacttccagggccacgagggc
tgcaacgagatcctcaacgtgaccaggcccgaggtggtgcgcggcatccacgacgcgtac
ttcgcggccggttccgactgcgtcgagacgaacacgttcggcgcgaacttcggcaacctg
ggcgagtacggcatcgtcgagcgcaccacggagctcgccgaggccggcgcccggctggcg
cgcgaggtcgccgacggctggtccagtccggaccggccgcggttcgtgctcggctcgatg
gggcccggcacgaagctgcccacgctcggccacgcgccgttcgccaccctgcgcgactcg
taccagcaggccgcggccggcctgatcaccggcggcgccgacgcgctgatcgtggagacc
tgccaggacctgctgcaggccaagtccgcggtgatcggggccaagcgggcgatggccgcg
gccggtgtcacggtgccgctgatctgccacgtcacggtcgagacgaccggaaccatgctg
gtcggcagcgagatcggcgcggcgctgaccgcgctggagccgctgggcgtcgacttcatc
ggcctcaactgcgcgaccggcccggccgagatggccgagcacctgcgctacctgtcccag
cacgcccgggtgcggctgtcggtgatgcccaacgccggcctgccggagctgaccccggac
ggcgcccgctacccgctgaccccggacgagctggccgccgcgctggacgagttcgtgtcc
gactacggtgcgtcgctggtcggcggctgctgcggcaccacgccggagcacatcgcccgg
gtggccgagcgggtcgccggcacgaccccggcttcgcggacgccgagcaccgagcccggc
gtgtcctcgatgtaccaccacgtgccgttccggcaggacgccggcgtgctgatgatcgcc
gagcgcaccaacgccaacggctcgaaggtgttccgggacaagatgctcgccggcgacttc
gccggctgcgtggagatcgcccgggaccaggcccggtccggttcgcacctgctcgacctg
tgcatcgactacgtcggccgggacggcagcgtggacatgcgcgagatcgccggccggttc
gccaccgcgagcacgctgccgatcatgctcgactcgaccgagccggcggtgatcgaggcc
ggcctggagacgctcggcggccggtgcgtggtcaactcggtcaactacgaggacggcgac
gggccggagtcccggttcgcccgcgccatgccgatcatccgcgagcacggcgccgcggtc
gtcgcgctgaccatcgacgaggagggccaggcgcggaccgcggagtggaaggaacgcgtc
gcggtccgcatgatcgaggacctgaccggcaactggggcctgtccaccgccgacatcctg
gtcgactgcctgaccttcccggtgtccaccgggcaggaggagacccggcgcgacgcgctg
gagacgatcgaggcgatccggcgcatccacgcccggtacccggaggtcaacttcaccctc
ggcgtgtcgaacgtgtcgttcggcctgaacccggcggcccggcaggtgctcaattcggtg
ttcctgcacgagtgcgtgcaggccgggttgtcctcggcgatcgtgcacgcgagcaagatc
ctgccgatgtcgaagatcccggacgaccagcgcgaggtcgccctcgacctggtgtacgac
cggcgccgggagggctacgacccgctgcagaagctgatcgagatgttcgagggcgtcgac
gcggcgtccgcgcgggccagccgggcggaggagctcgccgcgttgccgctggtcgaacgg
ctcaagcggcgcatcatcgacggcgagcgcaacggcctggacgacgatctcgccgcggcg
ctggccgaggggtacagggcgctcgacatcgtcaacgacatcctgctggacggcatgaag
gtggtcggtgacctgttcgggtccggccagatgcagctgccgttcgtgctccagtcggcc
gaggtgatgaaggccgcggtggcctacctggagccgcacatggaggccaccgacgaggcc
ggcaagggcacgatcgtgctggccacggtcaagggcgacgtgcacgacatcggcaagaac
ctggtcgacatcatcctgtccaacaacgggtacacggtcgtcaacatcggcatcaagcag
ccgatcgcggcgatcctggaggcggccgagcagcaccaggccgacgtcatcggcatgtcc
ggcctgctggtcaagtcgaccgtggtgatgaaggacaacctggccgagatgatggcccgc
gggctgcactcgcgctggccggtgatgctcggcggcgccgcgctgacccgggcgtacgtg
gaggacgacctgcgcggccagttcgagggcgacgtgcactacgccaaggacgcgttcgag
ggcctgtcgctgatggacaaggtgatggcggcccgccgcggcggcgcaccggtcatcgac
ccggagcgcgaggcgcagctggcgaagcggcgcgagcgccgggcccggcagcagtccatg
gtcgccgacaccgcccccgacctgtacgacgcgtcggtgcgctcggacgtcgcgaccgac
gtggacgtgccccggccgccgttcttcgggaccagggtggccaagggcatcccgctcaac
gactacgcggcgatgctcgacgagcgggccaccttcctcggccagtgggggctcaagccc
acccgtggcggtgacggcccgtcgtacgaggagctggccgagtccgagggccggccccgg
ctgcggtactggctggagcggctcgccaccgacaagctcatcgaggcggccgtggtgtac
gggtacttcccgtgctactcggagggcaacgacctcgtcgtgctggacgagaacgggcac
tccgagcgggcccggttcaccctgccgcggcagcgtcgggaccgccggctgtgcatcgcc
gacttcttccgcccgaaggagtccggcgagctcgatgtggtggcgttccagctggtcacg
gtgggcccggcgatcagcgactacaccgcgaagctgttcgccgacaacgcctaccgcgac
tacctggaggtgcacgggctgtcggtgcagctggccgaggcgctcgcggagtactggcac
cgccggatccgcaccgagctggtgctgcccggcggcaccaccgtcgccgactccgacccg
ggcgatctcgccggcatgctgaagaccgagttccgcggctgccggtacgcgttcggctac
tcggcctgcccggatctggaggagcgggcgaaggtggtctcgctgctcgacccggaccgg
atcaacgtctcgctgtcggaggagtaccagctcagcccggagcagtcgaccgacgcgctg
gtcgtccaccaccccgaggcgagctacttcaacgcccgctga

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