Actinomyces slackii: NCTC11923_02074
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Entry
NCTC11923_02074 CDS
T06783
Symbol
aceE
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
asla
Actinomyces slackii
Pathway
asla00010
Glycolysis / Gluconeogenesis
asla00020
Citrate cycle (TCA cycle)
asla00620
Pyruvate metabolism
asla00785
Lipoic acid metabolism
asla01100
Metabolic pathways
asla01110
Biosynthesis of secondary metabolites
asla01120
Microbial metabolism in diverse environments
asla01200
Carbon metabolism
asla01210
2-Oxocarboxylic acid metabolism
Module
asla_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
asla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
NCTC11923_02074 (aceE)
00020 Citrate cycle (TCA cycle)
NCTC11923_02074 (aceE)
00620 Pyruvate metabolism
NCTC11923_02074 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NCTC11923_02074 (aceE)
Enzymes [BR:
asla01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
NCTC11923_02074 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
VEG75408
UniProt:
A0A3S4SUK4
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All DBs
Position
1:2512931..2515690
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AA seq
919 aa
AA seq
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MSPTSDSTPLIDGLLTKVADNDPDETSEWRESLDALIEEKGGPRARFILLSMLAQARKKN
VTVPGQTTTAYVNTIPVEDEPYFPGDEALERTYRRWLRWNAAVMVTRAQRPGIGVGGHIS
SYASTATLYEVGFNHFFRGKDHPGGGDHLFFQGHASPGNYARAFIEGRLSEADLDGFRQE
VSHPARGEGRGIPSYPHPRRMEDFWEYPTVSMGLGPAEAIYQAWFDKYLTGAGIKDTSQQ
HTWAFLGDGEMDEPESRGMLQLAAHQQLDNLTFVVNCNLQRLDGPVRGNGKIVQELEAFF
KGAGWNVIKVLWGRGWDQLLAADKDHALEHLMMETLDGDYQTFKANNGAYVREHFFNRDP
RTAELVKDWTDDEIWALQRGGNDYRKMYAAYKAATEHKGQPTVILAHTVKGYLLGEHFAG
RNATHQMKKLTLDDLKALRDRLHIPITDEQLEANPKMPPYYRPNQDDPALLYMLDRRRQL
GGFLPERRDSGKQLELPGDKTYEVLKAGSGKREIASTMAFVQLLKELIKDKGIGRRIVPI
VPDESRTFGLESLFPTKKIFNTQGQNYTPVDADMMLSYRESTSGQLMHTGINEAGSAALF
QVVGTSYSTHDEPMIPVYIFYSMFGFQRTADQFWAAGDQLARGFIIGATAGRTTLTGEGT
QHMDGHSPIIAATNDAVITYDPGYAYEMRHIVRDALERWYGPDSGRNRDVMYYLTVYNEP
IHQPAEPEDVDVEGIIRGLHRLQAAPEGEGPVVQLLASGVGLPWIEEARRLLAEDWGVRA
GTWSVTSWNELRREALEVERANFLAPDAEQRVPYVTSRLSEAQGPFIATSDYDHLIADQI
RPWVPGDYRTLGADGYGFSDTRAAARRHYLIDAQSVVVKALQALVDQGSLGRHVLSEAIG
RYDLHNVNAGTSGGQGGEA
NT seq
2760 nt
NT seq
+upstream
nt +downstream
nt
gtgagccctacaagcgactccacgcctctcatcgacggcctcctgaccaaggtcgccgac
aatgaccccgatgagaccagcgagtggcgcgaatccctcgacgccctcatcgaggagaag
ggcggtccccgggcgcgcttcatcctcttgtcgatgctcgcccaggcccgcaagaagaat
gtcaccgtccccgggcagaccaccaccgcctacgtcaacacgatcccggtggaggacgag
ccctacttccccggtgatgaggccctggagcgcacctaccgccgctggctgcgctggaac
gccgcggtcatggtcacacgcgcccagcgcccggggatcggggtgggcggccacatctcc
tcctacgcctccaccgccacgctctacgaggtgggcttcaaccacttcttccgcggcaag
gaccatcccggcggcggggaccacctcttcttccagggccacgcctcccccggcaactac
gcgcgagccttcatcgaggggcgcctgagcgaggccgatctcgacggcttccgccaggag
gtctcccaccccgcgcgcggcgagggccgcggcatcccctcctacccgcacccgcgccgc
atggaggacttctgggagtaccccaccgtgtccatgggcctgggcccggcagaggccatc
taccaggcctggttcgacaagtacctcaccggtgccggcatcaaggacaccagccagcag
cacacatgggccttcctgggcgacggcgagatggacgagcccgagtcccgcggcatgctg
cagctcgccgcccaccagcagctggacaacctgaccttcgtcgtcaactgcaacctccag
cggctcgacggcccggtgcgcggcaacggcaagatcgtccaggagctcgaggccttcttc
aagggcgcgggctggaacgtcatcaaggtcctgtggggccgcggctgggatcagctgctg
gccgcggacaaggaccacgccctggagcacctcatgatggagacgctcgacggcgactac
cagaccttcaaggccaataacggcgcctacgtgcgcgagcacttcttcaaccgcgatccg
cgcaccgccgagctcgtcaaggactggaccgatgacgagatctgggccctgcagcgcggg
ggcaacgactaccgcaagatgtacgccgcctacaaggccgccaccgagcacaagggccag
cccaccgtcatcctggcccacaccgtcaagggctacctgctgggcgagcacttcgccggg
cgcaacgccacccaccagatgaagaagctcaccctcgacgacctcaaggcgctgcgcgac
cgcctccacatcccgatcacggatgagcagctcgaggccaacccgaagatgccgccgtac
taccggcccaaccaggacgacccggccctgctctacatgctcgatcgccgtcgccagctc
ggcgggttcctgcccgagcgccgcgactccggcaagcagctcgagctccccggggacaag
acctatgaggtgctcaaggccggatcgggcaagcgcgagatcgcctcgaccatggccttc
gtccagctgctcaaggagctcatcaaggacaagggcatcgggcgccgcatcgtgccgatc
gttcccgacgagtcgcgcaccttcggcctggagtccctcttccccaccaagaagatcttc
aacacccagggccagaactacacgcccgtggatgccgacatgatgctgtcctaccgggag
tccacctccggccagctcatgcacaccggcatcaacgaggccggctcagccgccctgttc
caggtggtgggcaccagctactccacccatgacgagccgatgatcccggtctacatcttc
tactcgatgttcggcttccagcgcacggccgaccagttctgggcggccggggatcagctg
gcgcgaggcttcatcatcggggccaccgccgggcgcaccaccctgaccggtgagggcacc
cagcacatggatggccactcccccatcatcgcggccaccaacgacgccgtgatcacctac
gaccccggctacgcctacgagatgcggcacatcgtgcgcgacgccctggagcgctggtac
gggccggactcgggccgcaaccgggatgtcatgtactacctgacggtctacaacgagccc
atccaccagcccgctgagccggaggatgtcgacgtcgagggcatcatccgcggcctgcac
cgccttcaggcggcccctgagggcgagggaccggtggtccagctcctcgcctccggcgtg
gggctgccctggatcgaggaggcgcgccgcctcctggccgaggactggggcgtgcgcgca
gggacctggtcggtcaccagctggaacgagctgcgccgcgaggccctggaagtggagagg
gccaacttcctggctcccgacgccgagcagcgcgtcccctatgtgacctcccggctctcc
gaggcccagggccccttcatcgccaccagcgactacgaccacctcatcgccgaccagatc
cgcccctgggtcccgggcgactaccgcaccctgggcgccgacggctacggcttctccgac
acccgcgccgcggcgcgccgccactacctcatcgacgcccagtccgtcgtggtcaaggcg
ctccaggcgctggtcgatcagggatccctgggccgccacgtgctgtccgaggccatcggc
cgctacgacctccacaatgtcaacgccggaacctccggcggtcagggcggggaggcctga
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