Apodemus sylvaticus (European woodmouse): 127666227
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Entry
127666227 CDS
T10613
Symbol
Bace2
Name
(RefSeq) beta-secretase 2
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
asyl Apodemus sylvaticus (European woodmouse)
Pathway
asyl05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
asyl00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
127666227 (Bace2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
asyl01002
]
127666227 (Bace2)
Enzymes [BR:
asyl01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
127666227 (Bace2)
Peptidases and inhibitors [BR:
asyl01002
]
Aspartic peptidases
Family A1: pepsin family
127666227 (Bace2)
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GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
127666227
NCBI-ProteinID:
XP_052014973
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Position
15:complement(557225..655836)
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AA seq
514 aa
AA seq
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MGALLRALLLPLLPQWLLSAVPALAPAPFTLPLQVTGATNHRASAVSGLGTPELPRADGL
ALALEPVRATANFLAMVDNLQGDSGRGYYLEMLIGTPPQKVQILVDTGSSNFAVAGAPHS
YIDTYFDSESSSTYHPKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESE
NFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPNIFSMQMCGAGLPVAGSGT
NGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRD
ENASHSFRITILPQLYIQPMMGAGFNYECYRFGISSSTNALVIGATVMEGFYVVFDRAQR
RVGFAVSPCAEIAGTTVSEISGPFSTEDIASNCVPAQALNEPILWIVSYALMSVCGAILL
VLILLLLLPLHCRHAPRDPEVVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctgcttcgagcactcttgctcccgctgctgcctcagtggctcttgagtgcg
gtccccgcactggcccccgcgcccttcacgctgcccctccaagtgacaggggccacaaac
cacagagcctcggctgtttccgggctcgggacccctgagttaccccgggccgatggcctg
gccctcgcactggagcctgtcagggctaccgccaacttcttggctatggtggacaatctt
cagggagactctggccgtggctactacctggagatgctgatcgggacccctccacagaag
gtacagattcttgtggacaccggaagcagtaacttcgctgtggcaggtgccccacactcc
tacatagacacctactttgactcagagagctccagcacataccaccccaagggctttgat
gtcactgtgaagtacacacagggaagctggactggctttgttggtgaagaccttgtcacc
atcccaaaaggcttcaacacctctttcttggtcaatattgccactatttttgagtctgag
aatttctttttgcctgggattaaatggaatggaatccttggacttgcttatgctgccttg
gccaagccatcaagctctctggagaccttttttgattccctggtggcccaagcaaagatt
ccgaacattttctccatgcagatgtgcggggctggattgccagtagctggatctggtacc
aacggaggtagtcttgtcctgggtggaattgaaccaagtttgtataaaggagatatctgg
tataccccaattaaagaggaatggtactatcaaatagagatcctgaaattggaaattggg
ggccagagtcttaacctggactgcagagagtataacgcagacaaggccattgtggacagt
ggtaccacactcctgcgcctaccccagaaggtgtttgatgcagtggtggaagctgtggca
cgcacatctctgattccagagttttctgatggcttctggacgggggcccagctggcatgc
tggacaaattctgaaacaccatgggcgtatttccctaagatttctatctacctgagagat
gagaatgccagtcactctttcaggatcaccattctgccacagctctacattcagcccatg
atgggagctggtttcaattatgaatgctaccgttttggtatctcctcttccacaaatgcg
ctggtgattggtgccactgtgatggagggcttctacgtggtctttgacagagctcagagg
agggtgggctttgctgtgagtccctgtgcagagattgcaggtaccacagtgtctgaaatt
tctgggcccttttccaccgaagacatagccagcaactgtgttccagcacaagctctgaat
gaacccatcttgtggattgtgtcctatgccctgatgagtgtgtgcggggccattctccta
gttctgatcctccttctgctgctcccgctgcactgccgacatgccccccgagaccctgag
gtagttaacgatgagtcctcactagtcagacatcgatggaaatga
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