KEGG   Apodemus sylvaticus (European woodmouse): 127696212
Entry
127696212         CDS       T10613                                 
Symbol
Fgfr3
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X1
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
asyl  Apodemus sylvaticus (European woodmouse)
Pathway
asyl01521  EGFR tyrosine kinase inhibitor resistance
asyl04010  MAPK signaling pathway
asyl04014  Ras signaling pathway
asyl04015  Rap1 signaling pathway
asyl04020  Calcium signaling pathway
asyl04144  Endocytosis
asyl04151  PI3K-Akt signaling pathway
asyl04550  Signaling pathways regulating pluripotency of stem cells
asyl04810  Regulation of actin cytoskeleton
asyl05200  Pathways in cancer
asyl05206  MicroRNAs in cancer
asyl05219  Bladder cancer
asyl05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:asyl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    127696212 (Fgfr3)
   04014 Ras signaling pathway
    127696212 (Fgfr3)
   04015 Rap1 signaling pathway
    127696212 (Fgfr3)
   04020 Calcium signaling pathway
    127696212 (Fgfr3)
   04151 PI3K-Akt signaling pathway
    127696212 (Fgfr3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    127696212 (Fgfr3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    127696212 (Fgfr3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    127696212 (Fgfr3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    127696212 (Fgfr3)
   05206 MicroRNAs in cancer
    127696212 (Fgfr3)
   05230 Central carbon metabolism in cancer
    127696212 (Fgfr3)
  09162 Cancer: specific types
   05219 Bladder cancer
    127696212 (Fgfr3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    127696212 (Fgfr3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:asyl01001]
    127696212 (Fgfr3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:asyl04090]
    127696212 (Fgfr3)
Enzymes [BR:asyl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     127696212 (Fgfr3)
Protein kinases [BR:asyl01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   127696212 (Fgfr3)
CD molecules [BR:asyl04090]
 Proteins
  127696212 (Fgfr3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set FGFR3_TM C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 127696212
NCBI-ProteinID: XP_052054740
LinkDB
Position
11:complement(77275384..77290776)
AA seq 803 aa
MVVPACVLVFCVAVVAGATSEPPVPEQRAVRRAAELPGPEPSQQEQVTFGSGDTVELSCH
PPGGAPTGPTVWAKDGAGLVASHRILVGLQRLQVLNASHEDAGVYVCQHRLTRRVLCHFS
VRVTDAPSSGDDEDGEDVAEDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSI
SWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVL
ERSPHRPILQAGLPANQTAILGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYV
TVLKSWISENVEADARLRLANVSERDGGEYLCRATNFIGVAEKAFWLRVHGPQAAEEELM
EADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKVSRFPLKRQQV
SLESNSSMNSNTPLVRIARLSSGEGPVLANVSELELPADPKWELSRTRLTLGKPLGEGCF
GQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLG
ACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSFDACRLPEEQLTCKDLVSCAYQVAR
GMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAP
EALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDL
YMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPSSSSS
GDDSVFTHDLLPPGPPSNGGPRT
NT seq 2412 nt   +upstreamnt  +downstreamnt
atggtagtcccggcctgcgtgctagtgttctgcgtggcggtcgtggctggagctacttcc
gagcctcctgttccagagcagcgagctgtgcggagagcggcagagcttccagggcctgaa
cctagccagcaggagcaggtgacgtttggcagtggggacaccgtggagctgagctgccac
ccgcccgggggtgcccccacaggccccactgtctgggctaaggatggtgcggggctggtg
gcctcccaccgcatcctggtagggcttcagaggcttcaagtgctaaatgcctcccatgag
gatgcaggggtctacgtctgccagcatcggctaactcggcgtgtgctatgccacttcagt
gtgcgagtgacagatgctccatcctcaggagatgacgaagatggggaggacgtggctgaa
gacacaggggctccttattggactcgcccagagcgcatggataagaaactgctggcagtg
ccagctgcaaacactgtacgcttccgctgccctgctgctggcaaccctaccccctccatt
tcctggctgaagaatggcaaagaattccgaggagagcatcgcattgggggcatcaagctc
cgccatcagcagtggagcttggtcatggaaagtgtggtgccctctgatcgtggcaactat
acctgcgtggtcgagaacaagttcggcagcatccggcagacgtacaccctggatgtgctg
gagcgctccccacaccggcccatcctgcaggctgggctgccggccaaccagacagccatt
ctgggcagtgacgtggagttccactgcaaggtgtacagcgatgcacagccacacatccag
tggctgaagcacgtggaagtgaacggcagcaaggtgggccctgacggcacgccctacgtc
acggtgctcaagtcctggatcagtgagaatgtggaggcagacgcacgcctccgcctggcc
aatgtgtcggagcgggacgggggcgagtacctctgtcgagccaccaatttcataggcgtg
gctgagaaggccttttggctgcgtgttcacgggccccaagcagctgaggaggagctgatg
gaagctgatgaggctggcagtgtgtacgcaggcatcctcagctacggggtgggcttcttc
ctcttcatcctggtggtggcggctgtgacgctctgccgcctgcgcagtcccccaaagaag
ggcctgggctcgcccaccgtgcacaaggtctctcgtttcccgcttaagcgacagcaggtg
tccttggaatccaactcctctatgaactccaacacacccctcgtgcggattgcccggctg
tcgtcaggagaaggtcctgttctggccaatgtttctgaacttgaactgcctgctgacccc
aagtgggagctctccaggacccggctgacactcggtaagcctcttggagaaggctgcttt
ggacaggttgtcatggctgaagctattggcatcgacaaggaccgtactgccaagcctgtc
actgtggccgtgaagatgttgaaagatgatgccactgacaaggacctgtcagacctggta
tctgagatggagatgatgaaaatgattggcaagcacaagaacatcattaacctgctgggg
gcctgcacccagggtgggcccctgtacgtgctggtggagtatgcagccaagggcaatcta
cgggagttcctgcgggctcggcgacctccgggcatggactactcctttgatgcctgcagg
ctaccagaagaacagcttacctgcaaggatctagtgtcctgtgcctaccaggtggcacga
ggcatggaatacttggcttcccagaagtgtattcacagagacttggctgccagaaatgtc
ctggtgaccgaggacaatgtgatgaagattgcagactttggcctggcccgagatgtgcac
aacctggattactacaagaagaccacaaatggccggctacctgtgaagtggatggcacca
gaggccctttttgaccgagtctacacccaccagagtgatgtctggtcctttggtgtcctt
ctctgggagatctttactctggggggctcaccgtatcctggcatcccagtggaagagctt
ttcaagctgttgaaagagggacaccgcatggacaagccagccaactgcacacatgacctg
tacatgatcatgcgggaatgttggcatgcagtgccttcacagaggcccaccttcaagcag
ttggtagaggatttagaccgcatcctcactgtgacatcaactgacgagtacttggacctc
tctgtgccgtttgagcagtactctccaggtggccaggatactcctagctccagctcgtcc
ggggatgactctgtgttcacccatgacctgctacccccaggcccacccagtaatggggga
cctcggacgtga

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