KEGG   ORTHOLOGY: K05094
Entry
K05094                      KO                                     

Symbol
FGFR3, CD333
Name
fibroblast growth factor receptor 3 [EC:2.7.10.1]
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map04010  MAPK signaling pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04144  Endocytosis
map04151  PI3K-Akt signaling pathway
map04550  Signaling pathways regulating pluripotency of stem cells
map04810  Regulation of actin cytoskeleton
map05200  Pathways in cancer
map05206  MicroRNAs in cancer
map05219  Bladder cancer
map05230  Central carbon metabolism in cancer
Disease
H00010  Multiple myeloma
H00022  Bladder cancer
H00458  Syndromic craniosynostoses
H00505  FGFR3-related short limb skeletal dysplasia
H00642  Lacrimo-auriculo-dento-digital syndrome
H00997  CATSHL syndrome
H01749  Achondroplasia
H01750  Thanatophoric dysplasia
H01754  Crouzon syndrome
H01990  Muenke syndrome
H02068  Hypochondroplasia
H02069  SADDAN
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   04014 Ras signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   04015 Rap1 signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   04020 Calcium signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   04151 PI3K-Akt signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   05206 MicroRNAs in cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   05230 Central carbon metabolism in cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
  09162 Cancer: specific types
   05219 Bladder cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05094  FGFR3, CD333; fibroblast growth factor receptor 3
Protein kinases [BR:ko01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   K05094  FGFR3, CD333; fibroblast growth factor receptor 3
CD molecules [BR:ko04090]
 Proteins
  K05094  CD333, FGFR3; fibroblast growth factor receptor 3
Other DBs
GO: 0005007
Genes
HSA: 2261(FGFR3)
PTR: 461067(FGFR3)
PPS: 100976551(FGFR3)
GGO: 101139997(FGFR3) 115932714 115932715
PON: 100433126(FGFR3)
NLE: 100591839(FGFR3)
MCC: 712829(FGFR3)
MCF: 102128947(FGFR3)
CSAB: 103246479(FGFR3)
CATY: 105585485(FGFR3)
PANU: 101014560(FGFR3)
RRO: 104678934(FGFR3)
RBB: 108532286(FGFR3)
TFN: 117085041(FGFR3)
PTEH: 111539069(FGFR3)
CJC: 100409938(FGFR3)
SBQ: 101051421(FGFR3)
MMUR: 105856032(FGFR3)
MMU: 14184(Fgfr3)
MCAL: 110293909(Fgfr3)
MPAH: 110330788(Fgfr3)
RNO: 84489(Fgfr3)
MCOC: 116069961(Fgfr3)
MUN: 110557305(Fgfr3)
CGE: 100764560(Fgfr3)
PLEU: 114694056(Fgfr3)
NGI: 103741127(Fgfr3)
HGL: 101711651(Fgfr3)
CCAN: 109695016(Fgfr3)
TUP: 102500041(FGFR3)
CFA: 488808(FGFR3)
VVP: 112922612(FGFR3)
VLG: 121489705(FGFR3)
AML: 100481826(FGFR3)
UAH: 113245744(FGFR3)
ORO: 101381434(FGFR3)
ELK: 111149137
MPUF: 101691659(FGFR3)
EJU: 114196996(FGFR3)
MLX: 118010795(FGFR3)
FCA: 100141386(FGFR3)
PYU: 121039432(FGFR3)
PBG: 122479132(FGFR3)
PPAD: 109269781(FGFR3)
AJU: 106978850(FGFR3)
HHV: 120231844(FGFR3)
BTA: 281769(FGFR3)
BOM: 102264670(FGFR3)
BIU: 109560724(FGFR3)
BBUB: 102395462(FGFR3)
OAS: 554324(FGFR3)
ODA: 120861835(FGFR3)
CCAD: 122428025(FGFR3) 122442295
SSC: 100514115(FGFR3)
CFR: 102512878(FGFR3)
CBAI: 105072182(FGFR3)
CDK: 105100875(FGFR3)
BACU: 103002473(FGFR3)
LVE: 103086424(FGFR3)
OOR: 101273169(FGFR3)
DLE: 111164861(FGFR3)
PCAD: 102982240(FGFR3)
ECB: 100034114(FGFR3)
EPZ: 103556997(FGFR3)
EAI: 106830606(FGFR3)
MMYO: 118665364(FGFR3)
MNA: 107524118(FGFR3)
HAI: 109390958(FGFR3)
SHON: 118987768(FGFR3)
AJM: 119035526(FGFR3)
MMF: 118633856(FGFR3)
PALE: 102878342(FGFR3)
PGIG: 120582906(FGFR3)
RAY: 107518024(FGFR3)
MJV: 108383914(FGFR3)
TOD: 119260900(FGFR3)
LAV: 100674054(FGFR3)
TMU: 101341002
MDO: 100023287(FGFR3)
SHR: 100913979(FGFR3)
PCW: 110212245(FGFR3)
OAA: 100084071(FGFR3)
GGA: 396515(FGFR3)
PCOC: 116225737(FGFR3)
MGP: 100543461(FGFR3)
CJO: 107313983(FGFR3)
NMEL: 110398027(FGFR3)
APLA: 101804995(FGFR3)
ACYG: 106034332(FGFR3)
TGU: 100218924(FGFR3)
LSR: 110473290(FGFR3)
SCAN: 103826117(FGFR3)
PMOA: 120509387(FGFR3)
OTC: 121334977(FGFR3)
GFR: 102044988(FGFR3)
FAB: 101812160(FGFR3)
PHI: 102114034(FGFR3)
PMAJ: 107203422(FGFR3)
CCAE: 111927721(FGFR3)
CCW: 104690922(FGFR3)
ETL: 114061475(FGFR3)
FPG: 101920747(FGFR3)
FCH: 102052231(FGFR3)
CLV: 102098275(FGFR3)
EGZ: 104130196(FGFR3)
NNI: 104018093(FGFR3)
PADL: 103920985(FGFR3)
AAM: 106498761(FGFR3)
AROW: 112965516(FGFR3)
NPD: 112942995(FGFR3)
DNE: 112990762(FGFR3)
ASN: 102371740(FGFR3)
AMJ: 106736800(FGFR3)
CPOO: 109322182(FGFR3)
GGN: 109303914(FGFR3)
PSS: 102444715(FGFR3)
CMY: 102939991(FGFR3)
CPIC: 101933794(FGFR3)
TST: 117878458(FGFR3)
CABI: 116817612(FGFR3) 116826290
PVT: 110085587(FGFR3)
PBI: 103067086(FGFR3)
TSR: 106555648
PGUT: 117664767(FGFR3)
PMUA: 114596954(FGFR3)
ZVI: 118078263 118096480(FGFR3)
XLA: 399347(fgfr3.S) 779370(fgfr3.L)
XTR: 100196923(fgfr3)
NPR: 108788840(FGFR3)
DRE: 58129(fgfr3)
CCAR: 109098492
IPU: 108263592
PHYP: 113539741(fgfr3)
AMEX: 103045058(fgfr3)
EEE: 113589671(fgfr3)
TRU: 101063860(fgfr3)
LCO: 104926793(fgfr3)
NCC: 104955633
CGOB: 115027139
ELY: 117267283(fgfr3)
PLEP: 121953470(fgfr3)
SLUC: 116036735(fgfr3)
ECRA: 117935936(fgfr3)
PFLV: 114546647
GAT: 120833006(fgfr3)
MSAM: 119910102(fgfr3)
CUD: 121526058(fgfr3)
MZE: 101476450(fgfr3)
ONL: 100689850(fgfr3)
OAU: 116329031(fgfr3)
OLA: 100049424(fgfr3)
OML: 112139739(fgfr3)
XMA: 102228238
XCO: 114134047(fgfr3)
XHE: 116708872(fgfr3)
PRET: 103458160
CVG: 107087110
CTUL: 119796224(fgfr3)
NFU: 107391665
ALIM: 106519945(fgfr3)
AOCE: 111580110(fgfr3)
CSEM: 103383204(fgfr3)
LCF: 108889150(fgfr3)
SDU: 111226196(fgfr3)
SLAL: 111646819(fgfr3)
XGL: 120795599(fgfr3)
HCQ: 109520993(fgfr3)
BPEC: 110155643(fgfr3)
MALB: 109962419(fgfr3)
OMY: 110519382(fgfr3)
ELS: 105015916(fgfr3)
SFM: 108920925(fgfr3)
PKI: 111844207(fgfr3)
AANG: 118227480(fgfr3)
LOC: 102691474(fgfr3)
LCM: 102364583(FGFR3)
CMK: 103181516(fgfr3)
DME: Dmel_CG7223(htl)
DER: 6552001
DGR: 6568139
CCAT: 101461001
BBIF: 117205543
BVK: 117230758
CGIG: 122394896
FEX: 115239000
CCIN: 107271667
LDC: 111506930
APLN: 108740541
PPYR: 116165339
OTU: 111425220
MSEX: 115446494
PPOT: 106102608
PXU: 106114513
FOC: 113215199
CSEC: 111872649
DMK: 116918797
HAME: 121877401
BGT: 106071935
GAE: 121383688
PMAX: 117339943
HMG: 100206525(FGFR) 100214111
 » show all
Reference
  Authors
Terada M, Shimizu A, Sato N, Miyakaze SI, Katayama H, Kurokawa-Seo M
  Title
Fibroblast growth factor receptor 3 lacking the Ig IIIb and transmembrane domains secreted from human squamous cell carcinoma DJM-1 binds to FGFs.
  Journal
Mol Cell Biol Res Commun 4:365-73 (2001)
DOI:10.1006/mcbr.2001.0306
  Sequence
[hsa:2261]
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