KEGG   Aliarcobacter thereius: ATH_0132
Entry
ATH_0132          CDS       T07638                                 
Symbol
metH
Name
(GenBank) cobalamin-dependent methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
athr  Aliarcobacter thereius
Pathway
athr00270  Cysteine and methionine metabolism
athr00450  Selenocompound metabolism
athr00670  One carbon pool by folate
athr01100  Metabolic pathways
athr01110  Biosynthesis of secondary metabolites
athr01230  Biosynthesis of amino acids
athr04981  Folate transport and metabolism
Module
athr_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:athr00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    ATH_0132 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    ATH_0132 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    ATH_0132 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    ATH_0132 (metH)
   04980 Cobalamin transport and metabolism
    ATH_0132 (metH)
Enzymes [BR:athr01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     ATH_0132 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding B12-binding_2 CdhD
Other DBs
NCBI-ProteinID: QBF15229
LinkDB
Position
123753..127226
AA seq 1157 aa
MLKKIEELIKKQVLIIDGAMGTQLQAREIKNEYWQFEGNDLEGCNELLNLTAPHILEEIY
ENYAKAGANFISTNTFGSMPWVLDEYEIGHMSYELSKLAAIQAKKAISKYDTKESPKFVL
ASVGPGTKLPSLGHITYDYMYDGYKIMAQGLADGGTDVFLLETCQDPLQIKAALHALNDV
APQIPIMVSVTIELNGTMLIGTDAQAIAAILKPFNILSLGFNCGTGPVQVEKHIKALSEV
SRFPISVHANAGLPQNRGGKSFYPMGPEEFTSLQKSFLEINGVAFLGGCCGTTPEHIKQL
SEAVNDIVPKSPNGFLKASLASLFNIVPLKQEPAPLLIGERSNATGSKAFRELLKANDYE
GTLSVAQQQVRAGAHVIDVSVGFAGRDEREDMDKVVALYSQKISLPLMPDSTQIKALESA
LKQIGGRCIINSVNLEDGEEKFDEVCKLAKKFGAALVCLVIDEIGMAKSKERKLEVAERI
FDLCVNRHGFDPADLVFDMLTFTIGSGDEEYRTAGIETMEAIREFQIRHPEAGTTLGLSN
ISFGLAQNARIYLNSIYLDHCVKAGLTSAIVNVKHIIPLNKISDEDKKACDDLIFNNQKD
GDPLFKFIEHFSNVEDKAEQSDEEYQNLSPEEKVKKLLLDGDKERMIPLVLELKDLMAPE
IIVNEWLIDGMKVIGELFGSGQMQLPFVLQSAETMKTTVDALNPYLPKQEKASETTMVIG
TVKGDVHDVGKNLVDIILSNNGFKIINIGIKADLSKFIEAAKEHNADAIGMSGLLVKSTA
VMKENLEEMQKLGLKIPVMLGGAALTKSFVDDYCRTIYDGPIFYCRDAFDGVIAMQRVEK
GGELDTKMASDLIERIDTSDKVEKEVVEIPPYEEISMPERTFIVPPYWHRVAKTGDELDK
ELIFSWINHRVLFRQRWGYKRGKQTPEVFMKYEREVVEPTYEAIKEELISKKVFDPIAIH
SYFPCIAKDNKLYIFDKKYSYNNLEEAKNVPALSEAIKVMEFPRQRRKPFRCIADFFAND
RLDVIGFTLASAGLKISDYEREFYDKGEFTKYYQIHGVGVELAEALAEVLHKQIRLDWNI
VPNEGHKISDVQMKQYVGCRYSPGYAACPELSQSRDIFDLLNPEEFGIEISETFQMHPEQ
TTCAIVVHNKEANYYNV
NT seq 3474 nt   +upstreamnt  +downstreamnt
atgttaaaaaaaattgaagagttaataaaaaaacaagtcttaattattgatggagcaatg
ggaacacagcttcaagcaagagagataaaaaatgaatattggcaatttgaaggcaatgat
ttagaaggctgtaatgaactactaaatctaacagctccacatattttggaagagatttat
gaaaattatgcaaaagcaggtgcaaattttatatctacaaacacttttggaagtatgcct
tgggttttagatgagtatgaaattggtcatatgtcttatgaattatcaaaattagcagct
attcaagcaaaaaaagctatttcaaaatatgatacaaaagagagtccaaaatttgtatta
gcttctgttggaccaggtacaaaacttccatcacttggacatattacttatgattatatg
tatgatggttataaaataatggctcaaggtttagctgatggtggaacagatgttttttta
cttgaaacttgtcaagatccacttcaaataaaagcagctttacatgcattaaatgatgtt
gcaccacaaattcctattatggtttcagtaactattgaattaaatggaacaatgctaata
ggaacagatgcacaagcaatagctgctatcttaaaaccttttaatattttatctttagga
tttaactgtggaacaggacctgttcaagttgagaagcatataaaagcacttagtgaagtt
tcaagatttcctatttcagttcatgcaaatgcagggcttccacaaaatagaggtggaaaa
agtttttatccaatgggacctgaagagtttacaagtttacaaaaaagttttttagagata
aatggagttgcatttttaggtggatgttgtggaacaacacctgagcatataaagcaatta
agtgaagctgtaaatgatattgttccaaaatctcctaatggatttttaaaagcatcattg
gcatctttatttaatattgttccattaaaacaagaaccagcaccacttttaattggtgaa
agaagtaatgcaacaggaagtaaagcttttagagaacttttaaaggcaaacgattatgaa
ggaaccttaagtgttgcacagcaacaagtacgagctggagctcatgttattgatgtgagt
gttggatttgctgggcgtgatgaaagagaagatatggataaagttgttgctttatattct
caaaaaatttcacttccactgatgcctgattcaactcaaataaaagctctagaatctgct
ttaaaacaaattggtggaagatgtattataaactcagtaaatcttgaagatggtgaagag
aagtttgatgaggtttgtaaactagcaaagaaatttggtgcagctcttgtatgtttggtt
attgatgaaattggaatggcaaaatcaaaagagagaaaacttgaagttgcagagagaatt
tttgatttatgtgtaaatagacatggttttgatcctgctgatttagtatttgatatgctt
acatttactattggtagtggagatgaagagtacagaacagctggaatagaaacaatggaa
gcaataagagagtttcaaataagacatccagaagctggaacaacacttggattatcaaat
atatcttttggacttgctcaaaatgcaagaatttatctaaactctatctatcttgatcat
tgtgtaaaagcaggacttacaagtgctattgtaaatgtaaaacatattattcctctaaat
aaaataagcgatgaagataaaaaagcttgtgatgatttaatatttaataatcaaaaagat
ggtgatccactatttaaatttattgagcatttttcaaatgttgaagataaagcagagcaa
agtgatgaagagtatcaaaatttaagtccagaagaaaaagtaaagaaattacttttagat
ggagacaaagaaagaatgatacctttagttcttgaactaaaagatttgatggctcctgaa
attattgtaaatgagtggttgattgatggaatgaaagtaataggagagctatttggaagt
ggacagatgcaacttccatttgttcttcaaagtgcagaaactatgaaaacaactgttgat
gctttaaatccatatttgccaaaacaagaaaaagcaagtgaaacaactatggtgattggt
acagttaaaggagatgttcatgatgttggtaaaaacttagttgatattattttaagtaat
aatggatttaagattataaacataggaattaaagctgatttatcaaaatttatagaagct
gcaaaagagcataatgcagatgcaattggaatgagtggattacttgtaaaaagtacagct
gttatgaaagaaaatcttgaagagatgcaaaaacttggacttaaaattcctgttatgctt
ggtggagctgctcttacaaaaagctttgtagatgattattgtagaacaatttatgatgga
ccaatattttattgtagagatgcctttgatggtgttatagctatgcaaagagtagaaaaa
ggtggagaacttgatacaaaaatggcttctgatttaattgaaagaattgatacaagtgat
aaagtagagaaagaagtagtagaaattcctccatatgaggagatttctatgccagaaaga
acatttattgttccaccatattggcacagagttgcaaaaacaggtgatgaacttgataaa
gagcttattttttcttggataaatcatagagtattatttaggcaaagatggggatataaa
agaggaaaacagactcctgaagtatttatgaaatatgaaagagaagttgtagaaccaact
tatgaagctataaaagaagagttaattagtaaaaaagtatttgatccaatagctattcat
agctatttcccttgtattgcaaaagataataaactatatatttttgataaaaaatatagt
tataacaatcttgaagaggcaaaaaatgttccagctttaagtgaagctataaaagtgatg
gagtttccaaggcaaagaagaaaaccttttagatgtattgctgacttttttgcaaatgat
agattagatgttataggatttacacttgcaagtgcaggacttaaaataagtgattatgaa
agagaattttatgataaaggtgagtttacaaaatattatcaaattcatggtgttggagtt
gaattagcagaagctttagctgaggttttacacaaacaaataagacttgattggaatata
gttccaaatgaaggtcataaaataagtgatgttcagatgaaacaatatgtaggatgtaga
tattctccaggttatgcagcttgtccagaacttagtcaaagtagagatatttttgattta
ttaaatccagaagagtttggaattgaaataagtgagacttttcaaatgcatccagaacaa
acaacttgtgcaattgttgtccacaacaaagaagcaaattattataatgtataa

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