KEGG   Acidithiobacillus thiooxidans: GCD22_01355
Entry
GCD22_01355       CDS       T06281                                 
Symbol
ligA
Name
(GenBank) DNA ligase (NAD(+)) LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
atx  Acidithiobacillus thiooxidans
Pathway
atx03030  DNA replication
atx03410  Base excision repair
atx03420  Nucleotide excision repair
atx03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:atx00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    GCD22_01355 (ligA)
   03410 Base excision repair
    GCD22_01355 (ligA)
   03420 Nucleotide excision repair
    GCD22_01355 (ligA)
   03430 Mismatch repair
    GCD22_01355 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:atx03032]
    GCD22_01355 (ligA)
   03400 DNA repair and recombination proteins [BR:atx03400]
    GCD22_01355 (ligA)
Enzymes [BR:atx01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     GCD22_01355 (ligA)
DNA replication proteins [BR:atx03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     GCD22_01355 (ligA)
DNA repair and recombination proteins [BR:atx03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     GCD22_01355 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     GCD22_01355 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     GCD22_01355 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      GCD22_01355 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 HHH_5 BRCT DNA_ligase_ZBD Nlig-Ia PTCB-BRCT HHH BRCT_2 5_3_exonuc
Other DBs
NCBI-ProteinID: QFX95729
UniProt: A0A5P9XPX1
LinkDB
Position
1268958..1270991
AA seq 677 aa
MASANDRDLQRIMQLRAQLSEANAAYYQKDAPTLSDPEYDVLLRELQALENRYPQWHSAD
SPTQRVGAAPLNHFAEIHYRVPMTSLDNVFDDAGFADWLVRVYKGLGHEQVSMSAEPKFD
GLSVNIRYENGRLLQAGTRGDGSTGEDVTSNVRSIRNVPLQLKGKNWPNILEVRGEVVIP
VAAFERLNDERLRNHENPFANPRNAAAGSLRQLDSQVTAQRPLAFFPWGWGEVNAPLAET
HLEVLQQLAGWGFEVTSYLSKIDHLDDCREYYLKMQNLREQMPFEIDGLVFKVNDLHERE
RLGFTARAPRWAIAYKFPAHEEKTVVEDILASVGRTGVITPVAQLRPVQVGGVTVSRASL
HNQDEVDRKDIRVGDTVLVRRAGDVIPEVVMVILEARPEHTQPWQIPDHCPICGSEVLRL
SNEAAHRCMGGIYCPAQRVGAISHFASRKAMDIRGLGEKLITQLVDRELVKTVADIYSLN
EDVLCGLERMARKSAQNLLAEIAASRQTQLWRFLYALGIRQVGETTAKSLAEHFGDLDPL
MTADEAQLQNIPDVGPIVAESVQHFFAQSHNREVITALRTAGLHWEKVAPKSSGHLAGRI
FVLTGTLPQMSREEAKAAIEATGAKVSSSVSAKTDYVVLGADAGSKAEKAAKLGITVVDE
AQLLELLKESYTTLHMD
NT seq 2034 nt   +upstreamnt  +downstreamnt
gtggcatcagccaatgacagggatctgcagcgaattatgcaattacgcgcgcaactgagc
gaagccaatgccgcctactatcagaaagatgcgccgacgctcagcgatccagaatatgac
gtgctcctgcgggaacttcaggcactcgaaaatcgctatccacagtggcacagtgccgat
tcgccgacgcaaagggtaggtgcagcccccctcaatcattttgccgaaatacattatcgt
gtgcccatgacctctttggacaatgtgtttgacgatgcgggttttgcagactggttggtg
cgagtctacaaagggctgggacatgagcaggtcagcatgagcgcggagcccaaatttgat
ggtctttcggtcaacatccgctatgaaaacggacgattactgcaggcaggtacccgggga
gatggcagtaccggagaagacgtcaccagtaatgtgcggagtattcgcaatgtgcctttg
caactaaagggtaagaattggccgaacattcttgaggttcgtggcgaggtagtcattccg
gtcgcggcttttgagcgtttaaatgatgaacgtttacggaatcatgaaaacccgtttgcc
aatccccgcaatgcggcagcgggaagcttgcggcaactggattcacaggtcacggcgcaa
aggcccctcgcttttttcccctggggctggggagaagtgaatgcccccttggcagaaacc
catcttgaagtgttacagcaactggccggctggggatttgaagtaacttcttaccttagt
aagatcgatcatcttgatgattgtagagaatattatttaaaaatgcagaatttacgtgaa
caaatgccctttgaaatagatggcctggtgtttaaggtgaatgatttgcatgaacgggag
cgcctgggcttcacagcgcgcgcgccacgctgggctattgcctataaatttccggcgcac
gaggaaaaaacagtggttgaggacattctggcttcggtgggacgtacgggcgtgattacc
cctgttgcccaattgcgtcccgtgcaggtgggtggagtgaccgtcagtcgtgccagcttg
cataatcaggatgaagtagatcgcaaggatatccgggtaggcgatacggtattggtgcgg
cgggcgggtgatgtgattcctgaagtggtcatggtcatccttgaagccagaccggagcat
acccagccctggcagatacctgatcattgcccgatctgtggatcggaagtgttgcgtctc
agcaacgaagccgcgcatcgttgcatggggggtatttattgtccggcgcaaagagtgggt
gcaatcagtcatttcgcttcacgcaaggccatggatattcgtggtctgggcgaaaaactg
attacccaactggtagatcgtgaactggtcaaaacggtggctgatatttactccctcaat
gaagacgtgttgtgtggtctggagcgtatggcccgtaaatcggcacaaaatctgctcgcc
gaaattgcagcttcgcggcaaacacaactttggcgctttttgtatgccctgggtattcgt
caggtcggtgaaacgacagccaaatcactggctgagcactttggcgatcttgatccgctg
atgacggcagatgaggcacaactgcagaatattccggatgtagggcctattgtcgccgag
tccgtccagcatttttttgcgcaatcccataatcgggaagtgattacggccttgcgcact
gccggcctgcactgggagaaggtcgcgcccaaaagctctggacatttggctgggcgcata
tttgtcctgacaggaactctcccgcagatgagtcgggaagaagccaaggcggccattgag
gcaaccggggccaaggtcagtagttccgtctccgcgaaaaccgattatgtggtgttgggt
gcggatgcgggcagtaaggcagagaaggcagccaagctgggcattacggttgtggatgaa
gcgcagttgctggaactgttaaaggagtcatacacaaccctacatatggattga

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