Aerococcus sp. Group 1: HMPREF9243_0741
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Entry
HMPREF9243_0741 CDS
T01447
Symbol
gshAB
Name
(GenBank) glutamate--cysteine ligase/gamma-glutamylcysteine synthetase
KO
K28983
glutamate---cysteine ligase / glutathione synthase [EC:
6.3.2.2
6.3.2.3
]
Organism
aur
Aerococcus sp. Group 1
Pathway
aur00480
Glutathione metabolism
aur01100
Metabolic pathways
aur01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
aur00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00480 Glutathione metabolism
HMPREF9243_0741 (gshAB)
Enzymes [BR:
aur01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
HMPREF9243_0741 (gshAB)
6.3.2.3 glutathione synthase
HMPREF9243_0741 (gshAB)
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Paralog
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATPgrasp_ST
ATP-grasp_3
Dala_Dala_lig_C
GARS_A
Motif
Other DBs
NCBI-ProteinID:
AEA01618
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Position
752964..755258
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AA seq
764 aa
AA seq
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MNQVQNYIKNENTSALFQNTSIGIEKEGHRVTPEGHIAQTPHPKNVDGSSENQYIQRDFA
ESQTELVSPPVIGREEGVLEWMHAIYDVTLAALDNEEAIWPYSMPPKLPSDDQIKVAQLD
DPAAVDYREYLVGAYGKKLQMISGLHYNFGLDPDFIKGFYQSEHSQFESLQEAQNALYLK
LARNFLRYQWVMVYFLGASPYAHDSFFEAGVEPLGHPVRSIRNSEHGYVNHEDVHVSYHD
LETYITSLENNVKTGHLYAEKEFYSNVRLRGGAKVRDLLHTGIKYLEVRNTDIQGDAPYG
IRLRELVFIKYFLLYLLWMDEMADDPEIEVGVKIKTQVANEDPFSQTAYYDEGKQIVSGL
RQMLADLGVSQEKVDLIEEVLHRLEAPEETPAAQIVKTYPSVDAWLESGLEIAETNRKNA
LKAPYQLGGFTDMELSTQIFMADAIRSGIQVEILDRSDNLLRLSVGDHREYVKNGNITSK
DTYISHYLLANKEVTKQIIQEAGFQAPKSRTYHSLSEVERAAGLYLNRPLVVKPKSTNMG
IGISIFKKGPSREELLEAGRIAFEADDSVLLEDYVPGVEYRFFVLDGKTIAVLLRVPANV
VGNGKATIAELVAEKNEDPKRGLDHRTPLEKIQLGDIESLNLKQQGLTFDSVLAEGQRAY
LRENSNISTGGDSIDVTDQVHPSYLDIASQMADALEVNITGIDLMIADITKAAQVTNEGA
NYGFIEANFNPMMMMHVYPAQGQGVRVTEALLHYLFPEKKFLDK
NT seq
2295 nt
NT seq
+upstream
nt +downstream
nt
atgaatcaagtacaaaactatatcaaaaatgaaaatacctcagctttatttcaaaacacc
tccattggaattgaaaaagaaggccaccgggtaaccccagaagggcatattgcccaaacg
cctcatcccaaaaatgttgatggatccagtgaaaaccagtatatccagcgcgattttgct
gaatcgcaaaccgaactcgtctcgccacccgtgattggccgtgaagagggcgttctggag
tggatgcatgccatctatgacgtcacccttgccgccttagataatgaggaagccatttgg
ccttacagtatgccaccaaaattgcctagtgatgaccagattaaggtggcccaactggat
gaccctgccgcagtagattaccgggaatatctagtgggagcctatggtaagaaactacaa
atgatttctggcctccactataactttggcctcgatcccgacttcatcaagggtttctac
cagtctgaacatagccaatttgaaagcttacaggaggctcaaaatgccctctatttaaaa
cttgcccggaactttttacgctatcaatgggtgatggtttatttcttaggagctagtccc
tatgcccacgactccttctttgaggctggagtggagcctcttggccatccggtgcggagt
atccgtaattctgagcatggctatgttaaccatgaagatgtccatgtttcttaccacgat
ctagaaacttacatcactagcctagaaaacaatgttaaaaccggtcacctttatgctgag
aaggaattttattctaacgtgcgtttacggggtggcgctaaggtcagagacctcctccat
accggaattaaatacttggaagtgcgcaataccgatatccaaggcgatgcgccctatggg
attcgcttaagagaacttgttttcattaaatacttcttactctatctgctttggatggat
gagatggctgatgacccggaaattgaagtgggcgttaagattaagacccaagtcgctaat
gaagatcctttcagccaaacggcctactatgatgaaggcaagcagatcgtcagtggtttg
cggcaaatgctagcggacttaggagtgagccaagagaaagtggacctgattgaggaagtt
cttcatcgtttggaagcaccagaagagaccccagcggctcagattgtaaaaacttatccc
agtgtggacgcctggttagaatccggtttggaaattgccgaaaccaaccgcaaaaatgct
ctcaaggcgccttatcaattaggtggctttaccgatatggaattgtctacccagatcttt
atggcagatgccattcgctccgggatccaggtagagattctagaccggtctgataacctc
ctccgcctctcggtcggagaccacagggaatatgtcaaaaatggcaatatcaccagcaag
gatacctatatttcccactatctcttagccaataaagaagtcaccaaacaaattatccaa
gaggctggtttccaagcccccaaatcgcggacctatcacagcctaagtgaggtggaaagg
gcagccggactctatcttaaccgccccttagtggttaaacccaaatcaaccaatatgggc
attggtatttccatctttaaaaagggacctagccgtgaagaacttttagaggccggtcgg
attgcctttgaagcggatgacagtgtgctcttagaagactatgtgccaggggtagagtac
cgcttctttgtcctggatggtaagaccatcgctgttttactcagagtgcctgctaatgtg
gtgggcaatgggaaggcgaccatcgcagaattagtcgctgagaagaatgaagaccctaag
cgaggcttagaccaccggactccactggaaaaaattcaactaggagacatcgaatccttg
aaccttaaacaacagggtttgacctttgacagcgtcttggctgagggtcagcgggcttac
ttaagggaaaactccaatatttctactgggggcgactcgatcgatgttaccgatcaggtt
catccctcctatcttgacattgccagtcaaatggctgatgccttagaagtgaacattaca
gggatcgacctgatgattgcagatattacaaaagctgcccaagtgaccaatgaaggggcc
aattatggctttatcgaagccaatttcaaccctatgatgatgatgcacgtctatccagcc
caaggccaaggggtccgtgtcactgaagccttgcttcattacctctttccagaaaagaaa
ttcttagataaataa
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