Actinomyces weissii: JG540_04580
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Entry
JG540_04580 CDS
T07198
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
awe
Actinomyces weissii
Pathway
awe00010
Glycolysis / Gluconeogenesis
awe00020
Citrate cycle (TCA cycle)
awe00620
Pyruvate metabolism
awe00785
Lipoic acid metabolism
awe01100
Metabolic pathways
awe01110
Biosynthesis of secondary metabolites
awe01120
Microbial metabolism in diverse environments
awe01200
Carbon metabolism
awe01210
2-Oxocarboxylic acid metabolism
Module
awe_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
awe00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
JG540_04580 (aceE)
00020 Citrate cycle (TCA cycle)
JG540_04580 (aceE)
00620 Pyruvate metabolism
JG540_04580 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
JG540_04580 (aceE)
Enzymes [BR:
awe01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
JG540_04580 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Motif
Other DBs
NCBI-ProteinID:
QQM68116
UniProt:
A0A7T7S2K3
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Position
complement(1107673..1110426)
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AA seq
917 aa
AA seq
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MSPTSDSTPLIDGLLSKVTDNDPEETKEWRDSLDALIKEKGAPRARFILLSMLADARRKN
VAVPAQTATPYVNTISVEDEPYFPGDEATERTYRRWLRWNAAVMVTRAQRPGVAVGGHIS
SYASTATLYEVGMNHFFRGKDHPGGGDHVFFQGHASPGNYARAFLEGRLTEADLDGFRQE
YSHPKEGRGLPSYPHPRRMEDFWEFPTVSMGLGPAEAIYQAWFDKYLQGAGIKDTSQQHT
WAFLGDGEMDEPESRGMIQLAANQQLDNLTFVVNCNLQRLDGPVRGNGKIVQELEAQFKG
AGWNVIKVLWGRGWDQLLAADKDHALEHLMMETLDGDYQAFKANDGAYVREHFFGRDPRT
AALVKDWTDEEIWALQRGGNDYRKVYAAYKAAMEHKGQPTLILAHTVKGYMLGTHFAGRN
ATHQMKKLTLEDLKGLRDRLHIPVTDEQLEANPKMPPYYRPAADDPALLYMLERRRQLGG
FVPERRDHGKELELPGDKAYDILKSGSGKQEVATTMAFVRLLKELLKEKGVGRRIVPIIP
DESRTFGMESLFPTKKIYNTLGQNYTPVDADMMLSYRESTSGQLMHTGINEAGSAALFQV
VGTSYATHGEPMIPVYIFYSMFGFQRTADQFWAAGDQLARGFIMGATAGRTTLAGEGTQH
MDGHSPLISGTNEAVVTYDPAYAYEIRHIVRDALERWYGPDSGRNRDIMYYLTVYNEPIV
QPAEPEGVDVEGIIKGLYKLDDAPAGEGPEVTLLASGVGVPWIREARDILLQDWGVRAST
WSVTSWNELRREALAAEKANFLSGDTAGQVPYLTRRLSEVQGPYIATSDFDHLVQDQIRA
WVPGDFHTLGADGFGFSDTRAAARRFFLIDAHSVVVKALQALVRQGRLDRSVLDQALSLY
ELENVHAGTSGSTGGEA
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccagtgactccactccgcttattgacggcctcctgagcaaggtcaccgac
aacgaccccgaggagaccaaggagtggcgcgactcgctagacgccctgatcaaggagaag
ggcgccccccgcgcccgcttcatcctgctgtccatgctggctgacgcgcgccgcaagaac
gtcgccgtcccggcccagaccgccaccccctacgtcaacaccatcagcgtggaggacgag
ccctacttccccggtgacgaggccaccgagcgcacctaccgccgctggctgcgctggaac
gcggccgtgatggtcacccgcgcccagcgccccggcgtcgccgtgggcgggcacatctcc
tcctacgcctccaccgccaccctctacgaggtgggcatgaaccacttcttccggggcaag
gaccaccccggcggcggtgaccacgtgttcttccagggccacgcctcccccggcaactac
gcccgcgccttcctggaggggcggctgaccgaggcggacctggacggcttccgccaggag
tactcccaccccaaggagggtcggggcctgccctcctacccgcacccgcgccgcatggag
gacttctgggagttccccaccgtctccatgggcctgggcccggcggaggccatctaccag
gcctggttcgacaagtacctgcagggcgctggtatcaaggacacctcccagcagcacacc
tgggccttcctgggcgacggcgagatggacgagcccgagtcccgcggcatgatccagctg
gccgccaaccagcagctggacaacctgaccttcgtggtcaactgcaacctgcagcgcctc
gacggccccgtgcgcggcaacggcaagatcgtccaggagctggaggcccagttcaagggc
gcgggctggaacgtcatcaaggtcctgtggggccgcggctgggaccagctcctggcggct
gacaaggaccatgccctggagcacctgatgatggagaccctggacggcgactaccaggcc
ttcaaggccaatgacggcgcctacgtgcgtgagcacttcttcgggcgcgacccccgcacc
gcggccctggtcaaggactggaccgacgaggagatctgggccctgcagcgtggcggcaac
gactaccgcaaggtctacgccgcctacaaggcggccatggagcacaagggccagcccacc
ctgatcctggcccacacggtcaagggctacatgctgggcacgcacttcgcggggcgcaac
gccacccaccagatgaagaagctcaccctggaggacctcaagggcctgcgcgaccggctg
cacatcccggtcacggacgagcagctggaggccaaccccaagatgccgccctactaccgt
ccggcagccgacgacccggcgctgctgtacatgctggagcggcgtcgccagctcggtggc
ttcgtacccgagcgccgcgaccacggcaaggagctggagctgcccggagacaaggcctac
gacatcctcaagtccggctccggcaagcaggaggtcgccaccaccatggccttcgtgcgc
ctgctcaaggagctgctcaaggagaagggcgtcggacggcgcatcgtgccgatcatcccg
gacgagtcgcggaccttcggcatggagtcgctgttccccaccaagaagatctacaacacc
ctggggcagaactacacgccggtggacgccgacatgatgctgtcctaccgggagtccacc
tccggccagctcatgcacaccggcatcaacgaggcgggctccgcggccctgttccaggtg
gttggcaccagctacgccacccacggcgagccgatgatccccgtgtacatcttctactcg
atgttcggcttccagcgcaccgcggaccagttctgggccgccggtgaccagctggcccgc
ggcttcatcatgggcgccaccgccgggcgcaccacgctggccggtgagggcacccagcac
atggacggccactcgccgctcatctccgggaccaacgaggccgtggtcacctacgacccc
gcctacgcctacgagatccggcacatcgtgcgtgacgccctggagcgctggtacggaccc
gactcgggccgcaaccgcgacatcatgtactacctgaccgtctacaacgagcccatcgtc
cagcccgccgagccggagggcgtggacgtggagggcatcatcaagggcctgtacaagctc
gacgacgcccccgccggtgagggcccagaggtcaccctgctggcctccggcgtgggtgtg
ccgtggatccgtgaggcccgcgacatcctgctgcaggactggggcgtgcgcgcctccacc
tggtccgtgaccagctggaacgagctgcgccgtgaggccctggccgctgagaaggccaac
ttcctctctggtgacaccgccgggcaggtcccctacctgacccgcaggctctcggaggtg
caggggccctacatcgccacgagcgacttcgaccacctggtgcaggaccagatccgtgcc
tgggtgccgggcgacttccacaccctgggtgcggacggcttcggcttctccgacacgcgt
gccgcagcccgccgcttcttcctgatcgacgcgcactcggtggtggtcaaggccctgcag
gcgctggtgcgtcagggcaggctggaccgttcggtgctggaccaggcgctgagcctctac
gagctggagaacgtacacgcgggcacctccggctcaaccggtggtgaggcctga
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