KEGG   Balaenoptera acutorostrata scammoni (minke whale): 103008077
Entry
103008077         CDS       T03086                                 
Symbol
PIK3R3
Name
(RefSeq) phosphoinositide-3-kinase regulatory subunit 3
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
bacu  Balaenoptera acutorostrata scammoni (minke whale)
Pathway
bacu01521  EGFR tyrosine kinase inhibitor resistance
bacu01522  Endocrine resistance
bacu01524  Platinum drug resistance
bacu04012  ErbB signaling pathway
bacu04014  Ras signaling pathway
bacu04015  Rap1 signaling pathway
bacu04024  cAMP signaling pathway
bacu04062  Chemokine signaling pathway
bacu04066  HIF-1 signaling pathway
bacu04068  FoxO signaling pathway
bacu04070  Phosphatidylinositol signaling system
bacu04071  Sphingolipid signaling pathway
bacu04072  Phospholipase D signaling pathway
bacu04081  Hormone signaling
bacu04140  Autophagy - animal
bacu04150  mTOR signaling pathway
bacu04151  PI3K-Akt signaling pathway
bacu04152  AMPK signaling pathway
bacu04210  Apoptosis
bacu04211  Longevity regulating pathway
bacu04213  Longevity regulating pathway - multiple species
bacu04218  Cellular senescence
bacu04360  Axon guidance
bacu04370  VEGF signaling pathway
bacu04380  Osteoclast differentiation
bacu04510  Focal adhesion
bacu04550  Signaling pathways regulating pluripotency of stem cells
bacu04611  Platelet activation
bacu04613  Neutrophil extracellular trap formation
bacu04620  Toll-like receptor signaling pathway
bacu04625  C-type lectin receptor signaling pathway
bacu04630  JAK-STAT signaling pathway
bacu04650  Natural killer cell mediated cytotoxicity
bacu04660  T cell receptor signaling pathway
bacu04662  B cell receptor signaling pathway
bacu04664  Fc epsilon RI signaling pathway
bacu04666  Fc gamma R-mediated phagocytosis
bacu04668  TNF signaling pathway
bacu04670  Leukocyte transendothelial migration
bacu04722  Neurotrophin signaling pathway
bacu04725  Cholinergic synapse
bacu04750  Inflammatory mediator regulation of TRP channels
bacu04810  Regulation of actin cytoskeleton
bacu04910  Insulin signaling pathway
bacu04914  Progesterone-mediated oocyte maturation
bacu04915  Estrogen signaling pathway
bacu04917  Prolactin signaling pathway
bacu04919  Thyroid hormone signaling pathway
bacu04923  Regulation of lipolysis in adipocytes
bacu04926  Relaxin signaling pathway
bacu04929  GnRH secretion
bacu04930  Type II diabetes mellitus
bacu04931  Insulin resistance
bacu04932  Non-alcoholic fatty liver disease
bacu04933  AGE-RAGE signaling pathway in diabetic complications
bacu04935  Growth hormone synthesis, secretion and action
bacu04960  Aldosterone-regulated sodium reabsorption
bacu04973  Carbohydrate digestion and absorption
bacu05010  Alzheimer disease
bacu05017  Spinocerebellar ataxia
bacu05020  Prion disease
bacu05100  Bacterial invasion of epithelial cells
bacu05135  Yersinia infection
bacu05142  Chagas disease
bacu05146  Amoebiasis
bacu05160  Hepatitis C
bacu05161  Hepatitis B
bacu05162  Measles
bacu05163  Human cytomegalovirus infection
bacu05164  Influenza A
bacu05165  Human papillomavirus infection
bacu05166  Human T-cell leukemia virus 1 infection
bacu05167  Kaposi sarcoma-associated herpesvirus infection
bacu05168  Herpes simplex virus 1 infection
bacu05169  Epstein-Barr virus infection
bacu05170  Human immunodeficiency virus 1 infection
bacu05171  Coronavirus disease - COVID-19
bacu05200  Pathways in cancer
bacu05203  Viral carcinogenesis
bacu05205  Proteoglycans in cancer
bacu05206  MicroRNAs in cancer
bacu05207  Chemical carcinogenesis - receptor activation
bacu05208  Chemical carcinogenesis - reactive oxygen species
bacu05210  Colorectal cancer
bacu05211  Renal cell carcinoma
bacu05212  Pancreatic cancer
bacu05213  Endometrial cancer
bacu05214  Glioma
bacu05215  Prostate cancer
bacu05218  Melanoma
bacu05220  Chronic myeloid leukemia
bacu05221  Acute myeloid leukemia
bacu05222  Small cell lung cancer
bacu05223  Non-small cell lung cancer
bacu05224  Breast cancer
bacu05225  Hepatocellular carcinoma
bacu05226  Gastric cancer
bacu05230  Central carbon metabolism in cancer
bacu05231  Choline metabolism in cancer
bacu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bacu05415  Diabetic cardiomyopathy
bacu05417  Lipid and atherosclerosis
bacu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    103008077 (PIK3R3)
   04014 Ras signaling pathway
    103008077 (PIK3R3)
   04015 Rap1 signaling pathway
    103008077 (PIK3R3)
   04370 VEGF signaling pathway
    103008077 (PIK3R3)
   04630 JAK-STAT signaling pathway
    103008077 (PIK3R3)
   04668 TNF signaling pathway
    103008077 (PIK3R3)
   04066 HIF-1 signaling pathway
    103008077 (PIK3R3)
   04068 FoxO signaling pathway
    103008077 (PIK3R3)
   04070 Phosphatidylinositol signaling system
    103008077 (PIK3R3)
   04072 Phospholipase D signaling pathway
    103008077 (PIK3R3)
   04071 Sphingolipid signaling pathway
    103008077 (PIK3R3)
   04024 cAMP signaling pathway
    103008077 (PIK3R3)
   04151 PI3K-Akt signaling pathway
    103008077 (PIK3R3)
   04152 AMPK signaling pathway
    103008077 (PIK3R3)
   04150 mTOR signaling pathway
    103008077 (PIK3R3)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    103008077 (PIK3R3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103008077 (PIK3R3)
  09143 Cell growth and death
   04210 Apoptosis
    103008077 (PIK3R3)
   04218 Cellular senescence
    103008077 (PIK3R3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103008077 (PIK3R3)
   04550 Signaling pathways regulating pluripotency of stem cells
    103008077 (PIK3R3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103008077 (PIK3R3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103008077 (PIK3R3)
   04613 Neutrophil extracellular trap formation
    103008077 (PIK3R3)
   04620 Toll-like receptor signaling pathway
    103008077 (PIK3R3)
   04625 C-type lectin receptor signaling pathway
    103008077 (PIK3R3)
   04650 Natural killer cell mediated cytotoxicity
    103008077 (PIK3R3)
   04660 T cell receptor signaling pathway
    103008077 (PIK3R3)
   04662 B cell receptor signaling pathway
    103008077 (PIK3R3)
   04664 Fc epsilon RI signaling pathway
    103008077 (PIK3R3)
   04666 Fc gamma R-mediated phagocytosis
    103008077 (PIK3R3)
   04670 Leukocyte transendothelial migration
    103008077 (PIK3R3)
   04062 Chemokine signaling pathway
    103008077 (PIK3R3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103008077 (PIK3R3)
   04923 Regulation of lipolysis in adipocytes
    103008077 (PIK3R3)
   04929 GnRH secretion
    103008077 (PIK3R3)
   04915 Estrogen signaling pathway
    103008077 (PIK3R3)
   04914 Progesterone-mediated oocyte maturation
    103008077 (PIK3R3)
   04917 Prolactin signaling pathway
    103008077 (PIK3R3)
   04926 Relaxin signaling pathway
    103008077 (PIK3R3)
   04935 Growth hormone synthesis, secretion and action
    103008077 (PIK3R3)
   04919 Thyroid hormone signaling pathway
    103008077 (PIK3R3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    103008077 (PIK3R3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103008077 (PIK3R3)
  09156 Nervous system
   04725 Cholinergic synapse
    103008077 (PIK3R3)
   04722 Neurotrophin signaling pathway
    103008077 (PIK3R3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103008077 (PIK3R3)
  09158 Development and regeneration
   04360 Axon guidance
    103008077 (PIK3R3)
   04380 Osteoclast differentiation
    103008077 (PIK3R3)
  09149 Aging
   04211 Longevity regulating pathway
    103008077 (PIK3R3)
   04213 Longevity regulating pathway - multiple species
    103008077 (PIK3R3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103008077 (PIK3R3)
   05206 MicroRNAs in cancer
    103008077 (PIK3R3)
   05205 Proteoglycans in cancer
    103008077 (PIK3R3)
   05207 Chemical carcinogenesis - receptor activation
    103008077 (PIK3R3)
   05208 Chemical carcinogenesis - reactive oxygen species
    103008077 (PIK3R3)
   05203 Viral carcinogenesis
    103008077 (PIK3R3)
   05230 Central carbon metabolism in cancer
    103008077 (PIK3R3)
   05231 Choline metabolism in cancer
    103008077 (PIK3R3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103008077 (PIK3R3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103008077 (PIK3R3)
   05212 Pancreatic cancer
    103008077 (PIK3R3)
   05225 Hepatocellular carcinoma
    103008077 (PIK3R3)
   05226 Gastric cancer
    103008077 (PIK3R3)
   05214 Glioma
    103008077 (PIK3R3)
   05221 Acute myeloid leukemia
    103008077 (PIK3R3)
   05220 Chronic myeloid leukemia
    103008077 (PIK3R3)
   05218 Melanoma
    103008077 (PIK3R3)
   05211 Renal cell carcinoma
    103008077 (PIK3R3)
   05215 Prostate cancer
    103008077 (PIK3R3)
   05213 Endometrial cancer
    103008077 (PIK3R3)
   05224 Breast cancer
    103008077 (PIK3R3)
   05222 Small cell lung cancer
    103008077 (PIK3R3)
   05223 Non-small cell lung cancer
    103008077 (PIK3R3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103008077 (PIK3R3)
   05170 Human immunodeficiency virus 1 infection
    103008077 (PIK3R3)
   05161 Hepatitis B
    103008077 (PIK3R3)
   05160 Hepatitis C
    103008077 (PIK3R3)
   05171 Coronavirus disease - COVID-19
    103008077 (PIK3R3)
   05164 Influenza A
    103008077 (PIK3R3)
   05162 Measles
    103008077 (PIK3R3)
   05168 Herpes simplex virus 1 infection
    103008077 (PIK3R3)
   05163 Human cytomegalovirus infection
    103008077 (PIK3R3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103008077 (PIK3R3)
   05169 Epstein-Barr virus infection
    103008077 (PIK3R3)
   05165 Human papillomavirus infection
    103008077 (PIK3R3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    103008077 (PIK3R3)
   05100 Bacterial invasion of epithelial cells
    103008077 (PIK3R3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103008077 (PIK3R3)
   05142 Chagas disease
    103008077 (PIK3R3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103008077 (PIK3R3)
   05017 Spinocerebellar ataxia
    103008077 (PIK3R3)
   05020 Prion disease
    103008077 (PIK3R3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103008077 (PIK3R3)
   05418 Fluid shear stress and atherosclerosis
    103008077 (PIK3R3)
   05415 Diabetic cardiomyopathy
    103008077 (PIK3R3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    103008077 (PIK3R3)
   04932 Non-alcoholic fatty liver disease
    103008077 (PIK3R3)
   04931 Insulin resistance
    103008077 (PIK3R3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103008077 (PIK3R3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103008077 (PIK3R3)
   01524 Platinum drug resistance
    103008077 (PIK3R3)
   01522 Endocrine resistance
    103008077 (PIK3R3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bacu04131]
    103008077 (PIK3R3)
Membrane trafficking [BR:bacu04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    103008077 (PIK3R3)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 SH2_1 Cupin_8 Exonuc_VII_L
Other DBs
NCBI-GeneID: 103008077
NCBI-ProteinID: XP_007164591
LinkDB
Position
Un
AA seq 461 aa
MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAITNGMKDGSVSL
QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
KYGFSDPLTFNSVVELISHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
IERFRKEGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKP
DLIQLRKIRDQHLVWLNHKGVRQKRLNAWLGIKNEDAAETYFINEEDENLPHYDEKTWFV
EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
NT seq 1386 nt   +upstreamnt  +downstreamnt
atgtacaatacggtgtggagtatggaccgcgatgacgcagactggagggaggtgatgatg
ccctattcgacagaactgatattttatattgaaatggatcctccagctcttccaccaaag
ccaccgaagccaatgacttcagccattacaaatggaatgaaggacggttctgtttctctt
caggatgcagaatggtactggggagatatttcaagggaggaggtaaatgacaaattacgg
gacatgccagatggtaccttcttggtcagagatgcctcaacaaaaatgcagggagattac
actttgactttgcggaagggaggcaataataagctaataaagatctatcatcgagatggt
aaatatggcttttctgatcctctgacatttaattctgtggtggagctcattagccactat
catcatgaatctcttgctcagtacaatcccaaacttgatgtgaagctgatgtacccagtg
tccagataccaacaggatcagttggtaaaagaagataacattgatgcagtaggtaaaaaa
ctgcaagagtatcactctcagtatcaggaaaagagtaaagagtatgacaggctatatgaa
gaatataccagaacatcccaggaaatacagatgaagaggactgcaattgaagcttttaat
gaaacaattaaaatatttgaagagcagtgtcatacacaagagcaacatagcaaagaatat
attgagcgatttcggaaagaagggaatgaaaaggaaattgaacgaattatgatgaactat
gacaaattgaaatcacgtctgggtgagattcatgatagcaaaatgcgtctagagcaggat
ttgaagaaacaagctttggacaaccgggaaatagataaaaaaatgaacagtatcaaacct
gacctgatccagctgcgcaagatccgagatcagcaccttgtgtggctcaatcacaaagga
gtaagacagaagcgcctaaatgcctggctgggaatcaagaatgaggatgctgctgagacc
tattttatcaatgaggaagatgaaaacctgccccattatgatgaaaaaacctggtttgtt
gaggatatcaatcgagtacaagcagaggacttgctttatgggaaacctgatggtgcattc
ttaattcgtgagagtagcaagaaaggatgttatgcttgctctgtggttgctgatggggaa
gtgaagcactgcgtgatctacagcactgctcggggctatggctttgccgagccctacaac
ctgtacagctcactgaaggagctggtgctccattaccagcagacatccctcgtccagcac
aatgactccctcaacgtcaggcttgcctaccctgtccacgcacagatgccctcgctctgc
agataa

DBGET integrated database retrieval system