Brevibacillus brevis: BBR47_22030
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Entry
BBR47_22030 CDS
T00879
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine methyltransferase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
bbe
Brevibacillus brevis
Pathway
bbe00270
Cysteine and methionine metabolism
bbe00450
Selenocompound metabolism
bbe00670
One carbon pool by folate
bbe01100
Metabolic pathways
bbe01110
Biosynthesis of secondary metabolites
bbe01230
Biosynthesis of amino acids
bbe04980
Cobalamin transport and metabolism
bbe04981
Folate transport and metabolism
Module
bbe_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
bbe00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
BBR47_22030 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
BBR47_22030 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
BBR47_22030 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
BBR47_22030 (metH)
04980 Cobalamin transport and metabolism
BBR47_22030 (metH)
Enzymes [BR:
bbe01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
BBR47_22030 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Met_synt_B12
Pterin_bind
B12-binding_2
B12-binding
CdhD
MtrH
Importin_rep_3
Motif
Other DBs
NCBI-ProteinID:
BAH43180
UniProt:
C0ZBM1
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All DBs
Position
2298104..2301550
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AA seq
1148 aa
AA seq
DB search
MKPTFREQLSRKILILDGAMGTMLQQANLTADDFGGEAYDGCNELLNLTRPDVIRSIHEK
YLEAGADIVETNTFGAASIVLAEYDVAEKDLEINIAAARLAREAVDAYSTEEWPRFVAGA
MGPTTKTLSLTGGVTFEELVEAYYRQAKGLILGGSDVLLLETSQDTLNVKAGGIGIRKAF
EELGQEIPVMLSGTIEPMGTTLAGQNIEAFYISLEHIKPVSIGLNCATGPEFMRDHLRTL
SGIAQCAVSCYPNAGLPDENGHYHETPQGLASKMRAFAEQGWINVAGGCCGTTPDHIQAM
AETLKDCKPRSTAVEPLSAVSGIEVVYVEDDNRPLLVGERTNVIGSKKFREMIAAGHYEE
ASDIARAQVKRGAHVIDICLADPDRDEYEDMEKFLQFIVKKVKAPLMIDSTDAKVMELGL
RYSQGKAILNSINLEDGLERFEEVVPLIHKFGASVVVGTIEEAGMAITREKKLEVAQRSY
DILVNQYGIKPQDIIFDPLVFPVGTGDEQYIGSAKETVEGIRLIKQAMPACKTILGVSNV
SFGLPPAGREVLNAVFLYHTTLAGLDYAIVNTEKLERYASIPEDERKLAEALLFETNDET
LAAFTEFYRQKKKEVSVEVSSLTLEERLARYVVEGSKDGLVEDLKLALDKYAPLEIINGP
LMTGMEEVGRLFNGNQLIVAEVLQSAEVMKASVSFLEPFMEKSDAAAKGKILLATVKGDV
HDIGKNLVEIILSNNGYNVVNLGIKVPPEQLIAACREEKPDAIGLSGLLVKSAQQMVITA
QDLRDAGIDIPMMVGGAALTRKFTSNRIAPEYRGIVLYAKDAMDGLDLVNRLQNPEERDR
LVEEQQHLLEAVATAQPVVEEKKAPLPARSAISRTVPIHLPPDCERHVLRQYPLSHLQPY
LNLRMLLGKHLGVRGNVDRLIEEGDEKVLELYGIVEELLKEAKQKGTITTHGVYQFFPAQ
SDGNDILVYDPKDHSKLLERFSFPRQLEEPHLCLSDFLRPVESKEMDYVGFLTVTAGGGI
REKSTELKDRGDYLRSHVLQSLALELAEAFAERIHHVMRDVWGIPDPVEMTMLERFGARY
QGIRVSFGYPACPNLEDQAQLFRLLRPEDIGVQLTEGFMMEPEASVSAMVFAHPEARYFN
AGPSIFEV
NT seq
3447 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccaacttttcgcgaacagctttcccggaaaattctgattctggacggtgcaatg
ggcaccatgcttcaacaggcgaacctgaccgctgatgatttcggcggtgaagcctatgat
ggctgtaatgaactcctgaacctgaccagaccagatgtgatccgttcgattcacgagaaa
tatttagaggcgggcgcagacattgtcgagacaaatacgtttggtgctgcttccattgtt
ttggctgagtacgatgtggcagagaaggaccttgaaatcaatatagcggcagcacgcttg
gccagagaagcggtggatgcctattccacggaggaatggccgcgttttgtagcaggtgca
atgggacctacgaccaaaaccctttcgttgacaggtggtgtcactttcgaagaactggtc
gaggcgtattatcgtcaggcaaaaggtctgattctcggtggctccgatgtgcttcttttg
gaaacttcgcaagatacgttgaacgtcaaggctggcggaatcgggattcgcaaagctttt
gaagagcttggacaggagatcccggtgatgctgtcaggtacgattgagccgatgggcacg
acgctggcgggtcaaaacatcgaggcgttttacatctccttggagcatataaagcctgtc
tctatcggtctgaactgtgcgacaggacccgagttcatgcgcgatcacctgcggacacta
tcaggaattgcccaatgtgcggtcagctgttatccgaatgcaggcttgccagacgagaat
ggccattaccatgaaacaccacagggacttgcttcgaaaatgcgagcattcgctgaacag
ggctggataaacgtcgctggcggctgctgtggaacaacgcctgaccatattcaagcgatg
gcagagaccttgaaagactgcaagccacggagtacagctgtagaaccgctgagcgcggtc
tccgggatcgaggtcgtttacgtcgaagatgacaatcgtcccttgctagttggggagaga
accaatgtcatcggttccaaaaaatttcgtgaaatgattgcagccggacactatgaagaa
gcatctgatattgcccgagcccaagtaaaacgtggcgcacacgtcatcgatatatgcttg
gctgaccccgaccgtgatgaatatgaagatatggaaaaattcctacagttcatcgtgaaa
aaagtaaaagcgcccctcatgatcgactcgacagatgccaaggtcatggagctgggactt
cgctattcgcaaggaaaggcgattctcaactcgatcaacttggaagacgggttggagcga
ttcgaggaagtcgtcccacttattcacaagttcggtgcctccgttgtcgttggaacgatt
gaggaagcgggtatggcgatcactcgcgaaaagaagctggaggtcgcgcagcgctcgtac
gacattcttgtcaaccagtacggaataaagccacaggatattattttcgatccactcgtc
tttccagtagggacaggggatgaacaatacatcggctctgcaaaggaaaccgtagaaggc
attcgtttgatcaaacaagcaatgcctgcttgcaagacgatcctgggtgtcagtaacgtt
tccttcggcttgcctcctgctgggcgggaagtgctgaacgcggtcttcttgtaccacacc
actctcgcagggcttgattacgccatcgtcaacacggagaagctggagcgctacgcttcg
attccggaagacgagagaaagctggcagaagcccttctattcgagacaaatgatgagaca
ttggcggctttcacagaattttatcgccaaaagaaaaaggaagtcagtgtggaagtctcc
tcgttaacgctcgaagaacgcttggcccgttatgtagtcgaaggctccaaggatggtctg
gtggaagacctgaagctggctctggataaatacgcaccgctcgagatcatcaacggtccg
ttgatgacggggatggaagaggtcggtcgcctattcaacggcaaccagctgatcgtggca
gaagtattgcagagcgcggaagtcatgaaggcttctgtatcatttttagagccgttcatg
gaaaaaagcgatgccgctgccaaggggaaaatcttgttggcgacagtcaagggtgatgta
cacgacatcgggaaaaacctcgtggaaattattttgtcaaacaacggctacaatgtcgtg
aacctaggaatcaaggtaccaccagagcaactgattgctgcatgcagagaagaaaagccg
gatgccatcggtctgtctggactcttggtaaaatccgcgcagcaaatggtcattactgca
caagacctgcgtgatgcaggcattgatatcccgatgatggttggcggtgcggcgttaacg
cgcaagttcacatcgaatcggatcgcaccggaataccgtggaattgttttatacgcaaaa
gacgccatggatggtctggacctcgtgaatcgtctgcaaaatccggaagaacgagatcgc
ttggtagaggaacagcagcatctgctggaagctgtcgcaacggctcagcctgttgtcgag
gagaaaaaagcacctttgccagctcgttcagccattagcagaaccgttccaatccatctg
ccgcccgattgtgaacgacatgttctgcgacaatacccgctgagccatctgcaaccgtat
ttgaacctgcggatgctcctcggaaaacacctcggtgtacgcggaaatgtagatagattg
atagaggaaggcgacgagaaggtactggaactatacggcattgtggaagagctattaaag
gaagcgaagcaaaaaggaaccattacgacacacggtgtgtatcagttcttcccggctcag
tcagatggcaacgatattttggtctatgatccaaaagaccacagcaagctgctggagcgc
ttttcgttcccgcgtcagctggaagaacctcatctctgcctgtccgacttcttgcgacca
gtcgagagcaaggaaatggattatgtcggattcctgaccgtaacggctggaggcgggatt
cgcgaaaaatcaacagagctaaaagatcgtggtgactacttgcgctctcatgtcctccaa
tccttggcattggagctggcagaggcatttgctgagcgaattcaccacgtcatgcgcgac
gtgtggggcataccggacccggttgagatgacgatgctagaacgtttcggagccagatac
caaggcattcgagtttccttcggttaccctgcttgcccgaacctggaagatcaggcgcag
ttattccgcctattgcgtccagaggatatcggcgttcagctgacagagggcttcatgatg
gagccagaggcttccgtatcggcgatggtatttgctcacccagaagcgcgttatttcaac
gcaggtccatctatttttgaagtttaa
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