Bison bison bison (American bison): 104980414 Help Entry 104980414         CDS       T08726                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism bbis  Bison bison bison (American bison) Pathway bbis00230   Purine metabolism bbis01100   Metabolic pathways bbis01522   Endocrine resistance bbis04015   Rap1 signaling pathway bbis04020   Calcium signaling pathway bbis04022   cGMP-PKG signaling pathway bbis04024   cAMP signaling pathway bbis04062   Chemokine signaling pathway bbis04072   Phospholipase D signaling pathway bbis04081   Hormone signaling bbis04082   Neuroactive ligand signaling bbis04114   Oocyte meiosis bbis04211   Longevity regulating pathway bbis04213   Longevity regulating pathway - multiple species bbis04261   Adrenergic signaling in cardiomyocytes bbis04270   Vascular smooth muscle contraction bbis04371   Apelin signaling pathway bbis04540   Gap junction bbis04611   Platelet activation bbis04713   Circadian entrainment bbis04714   Thermogenesis bbis04720   Long-term potentiation bbis04723   Retrograde endocannabinoid signaling bbis04724   Glutamatergic synapse bbis04725   Cholinergic synapse bbis04727   GABAergic synapse bbis04750   Inflammatory mediator regulation of TRP channels bbis04911   Insulin secretion bbis04912   GnRH signaling pathway bbis04913   Ovarian steroidogenesis bbis04914   Progesterone-mediated oocyte maturation bbis04915   Estrogen signaling pathway bbis04916   Melanogenesis bbis04918   Thyroid hormone synthesis bbis04921   Oxytocin signaling pathway bbis04923   Regulation of lipolysis in adipocytes bbis04925   Aldosterone synthesis and secretion bbis04926   Relaxin signaling pathway bbis04927   Cortisol synthesis and secretion bbis04928   Parathyroid hormone synthesis, secretion and action bbis04934   Cushing syndrome bbis04935   Growth hormone synthesis, secretion and action bbis04970   Salivary secretion bbis04971   Gastric acid secretion bbis04972   Pancreatic secretion bbis04976   Bile secretion bbis05032   Morphine addiction bbis05142   Chagas disease bbis05146   Amoebiasis bbis05163   Human cytomegalovirus infection bbis05166   Human T-cell leukemia virus 1 infection bbis05200   Pathways in cancer bbis05207   Chemical carcinogenesis - receptor activation bbis05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bbis00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     104980414 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     104980414 (ADCY1)    04371 Apelin signaling pathway     104980414 (ADCY1)    04020 Calcium signaling pathway     104980414 (ADCY1)    04072 Phospholipase D signaling pathway     104980414 (ADCY1)    04024 cAMP signaling pathway     104980414 (ADCY1)    04022 cGMP-PKG signaling pathway     104980414 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     104980414 (ADCY1)    04081 Hormone signaling     104980414 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     104980414 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     104980414 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     104980414 (ADCY1)    04062 Chemokine signaling pathway     104980414 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     104980414 (ADCY1)    04923 Regulation of lipolysis in adipocytes     104980414 (ADCY1)    04912 GnRH signaling pathway     104980414 (ADCY1)    04913 Ovarian steroidogenesis     104980414 (ADCY1)    04915 Estrogen signaling pathway     104980414 (ADCY1)    04914 Progesterone-mediated oocyte maturation     104980414 (ADCY1)    04921 Oxytocin signaling pathway     104980414 (ADCY1)    04926 Relaxin signaling pathway     104980414 (ADCY1)    04935 Growth hormone synthesis, secretion and action     104980414 (ADCY1)    04918 Thyroid hormone synthesis     104980414 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     104980414 (ADCY1)    04916 Melanogenesis     104980414 (ADCY1)    04925 Aldosterone synthesis and secretion     104980414 (ADCY1)    04927 Cortisol synthesis and secretion     104980414 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     104980414 (ADCY1)    04270 Vascular smooth muscle contraction     104980414 (ADCY1)   09154 Digestive system    04970 Salivary secretion     104980414 (ADCY1)    04971 Gastric acid secretion     104980414 (ADCY1)    04972 Pancreatic secretion     104980414 (ADCY1)    04976 Bile secretion     104980414 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     104980414 (ADCY1)    04727 GABAergic synapse     104980414 (ADCY1)    04725 Cholinergic synapse     104980414 (ADCY1)    04720 Long-term potentiation     104980414 (ADCY1)    04723 Retrograde endocannabinoid signaling     104980414 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     104980414 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     104980414 (ADCY1)    04213 Longevity regulating pathway - multiple species     104980414 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     104980414 (ADCY1)    04714 Thermogenesis     104980414 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     104980414 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     104980414 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     104980414 (ADCY1)    05163 Human cytomegalovirus infection     104980414 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     104980414 (ADCY1)    05142 Chagas disease     104980414 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     104980414 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     104980414 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     104980414 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     104980414 (ADCY1) Enzymes [BR:bbis01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      104980414 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom Motif Other DBs NCBI-GeneID:  104980414 NCBI-ProteinID:  XP_010827411 UniProt:  A0A6P3GCR5 LinkDB All DBs Position Unknown AA seq 1372 aa AA seqDB search MLEQVQQGPECGHVQILQTWDMPRTSTFTCSYFFLSHQVPPSSSFLGKGLLFPFPSFLDF CRLLWSCTFDALRVGLGPQREKLARQQGPLGVHLAEDGHCHQSLDSPCQDLQAHQNLGSL AGQRRQRRSEDAESPRICEPTTLGRKVTLRTPCTGPSPDRLCSPAPQLAPHPASPLLLGL DFFPAVSSSRSAASSHSKKHLELPTPGQQELGRHHVPRLDVRCHTLDKENGQLQKGLAAP TRAGPGTLAPWSALLRDLSSHAVSPHRPSRQLPHELLRDCSLGASRICTGSSMPHLSIWG CARARPPPHPHALSYSFNKHQSTCYIMRGSRIYCRPDRLRPLKRQQQIEDAGGGGKDLSV PGGVFWAVWYSASTPARTLPQAQKPQPGSPVTASTAASVNQRPLQATPASRLPSLCQPFC PLARASPPRPHWGPPLSPVSATGHLKSPGLQAQLGANALLFLGVNVYGVFVRILAERAQR KAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHD NVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGL TQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWS NDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVPSH RRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALR TASEKLRNRSSFSTNVVQTTPGTRVNRYIGRLLEARQMELEMADLNFFTLKYKQAERERK YHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHITRV QCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSWSSSPNGSLVVLSSGGRDPVLP VPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLELSGYTKAMGAGA ISGRSFEPIVAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMEKVKLDNKRILFN LLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNE IIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTRAKKCISSHLSTLADFAIEMF DVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQ VTEEVHRLLRRGSYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRSLNSERKMYPFGR AGLQTRLAAGHPPVXXXXXXPVGAGPGALQGSGLAPGPPGQHLPPGASGKEA NT seq 4119 nt NT seq  +upstreamnt  +downstreamnt atgctggagcaggtgcagcagggcccagagtgtggacatgtgcagattctgcagacctgg gacatgcccaggaccagcacatttacttgctcatatttctttctgtctcatcaggtgcca cccagctcctctttcctggggaaggggctgctgttcccctttcccagcttcctggatttc tgccgactcctctggagctgcacctttgatgccctcagagtggggctgggaccacagaga gagaagctggccaggcagcagggccctctgggagtccatcttgcggaagatggtcactgc caccagagcttagactccccttgtcaggacctgcaggcgcaccagaatctgggttctctt gctggccagagacgccagcgcagaagtgaggacgctgagtcccccaggatctgcgagccc accaccctggggaggaaagtgactctccgcactccctgcaccggaccctctcctgaccgc ctgtgcagccctgccccacagctggcccctcacccagcgtcgccccttctcctcgggctg gactttttcccagctgtgtcatcctctcgctcggcagccagctcccacagtaagaagcac ctagagttgccgacaccagggcagcaggaactagggaggcaccatgtgcccaggctggac gtcagatgccacactctggacaaggagaatggccagctgcagaagggcctggctgctcca acccgggccgggcctgggaccctggccccgtggtccgccctcctgcgtgacctgtcatcc catgcagtgtccccccaccgcccttctcggcagctgccccatgagctcctgcgagactgc agcctgggtgcctcccgcatctgcactggcagctccatgccgcatctgagcatctggggc tgtgccagggccaggccacctccccacccacatgccctcagttactcattcaacaaacac cagagcacctgctatattatgagaggttcccggatctattgccgacctgacagactgagg ccccttaagaggcagcagcagattgaggatgctggtgggggtggcaaggacctgtcagtc ccgggaggcgtgttctgggctgtgtggtactcagcctccaccccagcacggacccttccc caagctcagaagcctcagcctggctcccccgtcaccgcttctactgcagccagtgtgaac cagcgccctcttcaggccacacctgccagcagattgcccagcctctgccagcccttctgc ccgttggcccgcgcctctccgcccagacctcactggggacctccactttcccctgtttct gccacaggccacctgaaaagccctggcttgcaggctcaactgggtgccaacgctctgctc ttcctcggtgtgaacgtgtatggcgtcttcgtgaggatcctggctgagcgcgcccagagg aaggccttcctgcaggcccggaactgcattgaggaccggctgaggctggaggacgagaat gagaagcaggagcggctgctcatgagcctcctgcctcggaatgttgccatggagatgaag gaggacttcctgaagccccctgagaggattttccacaagatttacatccagcggcatgac aacgtgagcatcctctttgcagacatcgtgggcttcacaggcttggcgtcacagtgcaca gcccaggagctggtgaaactcctcaacgagctcttcgggaagtttgacgagctggccaca gagaaccactgccgccgcatcaagatcctgggagattgctactactgtgtgtctggcctc actcagcccaagactgaccacgcccactgctgtgtggagatgggcctggacatgatcgac accatcacgtccgtggctgaggccactgaggtggacttgaacatgcgtgtggggctgcac accggcagggtcctctgcggggtcctgggcctgcgtaagtggcagtatgatgtgtggtcc aacgacgtgaccctggccaacgtcatggaggccgccggcctgcctgggaaggttcacatc acaaagaccaccctggcgtgcctgaacggtgactatgaggtggagccgggacacggacac gagaggaacagttttctgaaaactcataacattgagaccttttttattgtgccctcgcat cggcgaaagatatttccagggctgattctctcagacataaaaccggccaagaggatgaag ttcaagaccgtgtgctacctgctggtgcagctcatgcactgccggaagatgttcaaggcc gagatccctttctccaacgtcatgacctgtgaggacgacgacaagcggagggcactgaga acagcctcggaaaaactcagaaaccgctcgtctttctctacaaacgttgtccaaaccacc cccggcacacgtgtcaacaggtacatcggccgcctcctggaagcccgccagatggagctg gagatggcagacctgaacttcttcaccctgaagtacaagcaagctgagcgagagcgaaag taccaccagcttcaggacgagtatttcaccagcgccgtggttctggctctcattctggcc gccttattcggccttgtctaccttctaataatcccacagagtgtggctgtcctgctcctg ctggtgttctgcatctgcttcctggtggcctgtgtcctgtacctgcacatcacccgggtc cagtgttttccagggtgcctgaccatccagatccgcaccgtcttgtgcatcttcatcgtg gtcttaatctactctgtggcccaaggctgtgtggtgggctgcctgccttggtcctggagc tccagtcccaacgggtccctggtggtcctgtcttctgggggccgggacccagtgctgcct gtgccgccctgcgagtctgcgccccacgccctgttgtgcggcctcgtgggcaccctcccg ctggccatattcctgcgggtctcctccttgccaaaaatgatcctgctcgccgtgctcacc acctcctacatcctcgtcctggagctcagcgggtacacgaaggccatgggggccggtgcc atctcagggcgcagcttcgagccgatcgtggccatcctgctattctcgtgcacgctggcc ctgcacgcccggcaggtggatgtcaagctgcggctggactacctctgggcggcccaggca gaggaggagcgggatgacatggagaaagtgaagctggacaacaagaggattctcttcaac ctcctgccagcccacgttgcccagcacttcctaatgtccaaccctcgaaacatggacctg tattaccagtcatactcgcaggtgggggtcatgtttgcatccatccccaacttcaatgac ttctacatcgagctggatggcaacaacatgggggtggaatgtctacgccttctgaatgag atcatcgctgactttgatgagctcatggacaaagacttttacaaggacctagagaagatc aagaccattgggagcacgtacatggctgctgtggggctggcgcccactgctgggaccagg gctaagaagtgcatctcctcccacctcagcacgttggcagattttgccatcgagatgttt gatgtcctggatgagatcaactaccagtcttataacgactttgtgctccgtgttggcatc aatgttggccccgtggtggctggagtgatcggggctcgcaggccgcagtatgacatttgg gggaacacggtcaatgtggccagtcggatggacagtaccggcgtccagggcaggatccag gtcacagaggaagttcaccggctgctgcggcggggttcctaccacttcgtgtgccgaggc aaagtcagtgtcaagggcaagggtgagatgctgacatacttcctggaaggcaggaccgat ggaaatggctcccaaaccaggtccctgaactcagagcggaaaatgtatcctttcggaaga gctggcctccagaccagactggctgcgggtcaccccccggtnnnnnnnnnnnnnnnnnnc ccagttggagctgggccaggggctctgcagggctcggggcttgccccaggccccccaggc caacacctgccccctggagcctctgggaaggaggcttag

DBGET integrated database retrieval system