Bison bison bison (American bison): 104982211 Help Entry 104982211         CDS       T08726                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism bbis  Bison bison bison (American bison) Pathway bbis04022   cGMP-PKG signaling pathway bbis04068   FoxO signaling pathway bbis04081   Hormone signaling bbis04140   Autophagy - animal bbis04152   AMPK signaling pathway bbis04211   Longevity regulating pathway bbis04213   Longevity regulating pathway - multiple species bbis04910   Insulin signaling pathway bbis04920   Adipocytokine signaling pathway bbis04923   Regulation of lipolysis in adipocytes bbis04930   Type II diabetes mellitus bbis04931   Insulin resistance bbis04932   Non-alcoholic fatty liver disease bbis04935   Growth hormone synthesis, secretion and action bbis05010   Alzheimer disease bbis05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:bbis00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     104982211 (IRS2)    04022 cGMP-PKG signaling pathway     104982211 (IRS2)    04152 AMPK signaling pathway     104982211 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     104982211 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     104982211 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     104982211 (IRS2)    04923 Regulation of lipolysis in adipocytes     104982211 (IRS2)    04920 Adipocytokine signaling pathway     104982211 (IRS2)    04935 Growth hormone synthesis, secretion and action     104982211 (IRS2)   09149 Aging    04211 Longevity regulating pathway     104982211 (IRS2)    04213 Longevity regulating pathway - multiple species     104982211 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     104982211 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     104982211 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     104982211 (IRS2)    04932 Non-alcoholic fatty liver disease     104982211 (IRS2)    04931 Insulin resistance     104982211 (IRS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS MEKK4_N Motif Other DBs NCBI-GeneID:  104982211 NCBI-ProteinID:  XP_010829851 UniProt:  A0A6P3GK31 LinkDB All DBs Position Unknown AA seq 743 aa AA seqDB search MVNRRPAPCSNARLVVLVLQRAVHGRFRTAESGEPPRPRRAPLPSWEKSWGSIPLSNLSR APDGPWGNLAPWPLQPRSRKSVFLMPVFASATVGFVACSDLNSGTPTLNSSPHSHLGDAL YVRRRPLPRLCALGRGSAGDWPRPRRPGSARRSPPSSWHDGNCSLLRPLVLPFLLLHLNR RFQLPENLQVNGADDAPERARDRARGKGSPERSAGAAAADDSYGLVAPATAAYREVWQVN LKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMSIRRCGHSDSFFFIEVGR SAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSATHPISVPG ARNTPESIAETPPARDGSAGELYGYMTMERPLSHCGGRAYRRVSGDGAPDLDRGLRKRTY SLTTPARQRPVPQPSSASLDEYTLMRATFSGSSGRLCPSCPASSPKVAYHPYPEDYGDIE IGSHRSSSSNLGTDDGYVPMTPGVALLGTGSGSCKSDDYMPMSPTSVSAPKQILQPRPVP AALPPAGATLSMESADSKLLPNGDYLNMSPSDKGTAGTPPDFFSAAGETLRCRAGWPHAA GLVCGSQCAFLRSSPVALVLLVGGPWLGAELGALAPVRLLEQMGKDRGVLALTWLSQTLN DEGEERREGVQTTVNTEYALLKSDSHQKNSLRTHHLVLPLVEQAGKTRAGLRRALGGGSR SKRNSELGLVPPGLKESKAFRIK NT seq 2232 nt NT seq  +upstreamnt  +downstreamnt atggtgaaccggcgcccggcaccctgcagcaacgcccgcctcgtggtcctggtgctgcag cgtgctgtacacgggcgtttccgcaccgcggagtcaggagaaccaccccgaccccgccgt gcccctctgccttcctgggagaagtcctggggctccatcccgctcagcaacctttcccgg gccccagatggtccctggggaaacctggcgccctggcctctccagccccgatcccggaag agcgtgtttctcatgcccgtctttgcttctgccactgtgggattcgtagcctgctcggat ctgaactcggggactcccaccctcaatagcagccctcacagtcatttaggagacgcgtta tatgtccggagacgcccactcccgcgcctctgcgcgctgggccgggggtcggcgggggac tggccgcggccgcggagacccggctcggctcgccggagcccgccctcttcctggcacgat ggaaactgcagtcttctccgcccgctcgtcctcccctttctcctgttacatctaaacaga cgatttcaacttcccgagaacctgcaagtgaatggcgctgatgacgccccggaaagggcc cgcgatcgggcgcgggggaagggcagccctgagcggtcggcgggcgccgctgcggccgat gacagctacgggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggtgaac ctgaagcccaagggtctgggccagagcaagaacctgacgggcgtgtaccgcctgtgcctg tcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacgctgcag ctcatgagcatccgccgctgcggccactcggacagcttcttcttcatcgaggtgggccgc tcggccgtgacgggccccggagagctgtggatgcaggcggatgactcggtggtggcgcag aacatccacgagaccatcctggaggccatgaaggcgctcaaggagctcttcgagttccgg ccgcgcagcaagagccagtcgtccggctcgtcggctacgcaccccatcagcgtgcccggc gcgcgcaacacgcccgagtccatcgctgagacgcccccggcgcgggacggcagcgcgggc gagctgtacggctacatgaccatggagcggccgctgagccactgcggcggccgcgcctac cgcagggtctctggggacggcgccccggacttggaccgagggctgaggaagcggacttac tcgctgaccacgcctgcccggcagcggccggtgccccagccgtcctccgcgtccctggac gagtacaccttgatgcgggccaccttctcgggcagctccggccgcctgtgcccatcctgc cccgcctcttctcccaaagtggcctaccacccttaccccgaggactacggcgacatcgag attggctcgcaccgcagctccagcagtaatctgggcacggacgatggctacgtgcccatg acccccggcgtggccctcctggggacgggcagcgggagctgcaagagcgacgactacatg cccatgagccccaccagcgtgtcggccccgaaacagatcctgcagccgcgccccgtgccc gccgccttgccccctgctggggccacgctgtccatggagagcgccgacagcaagctgctg cccaacggggactacctcaacatgtcccccagtgataagggcacggcgggcaccccgccc gacttcttctcggccgcgggggagacgctgcggtgccgggctgggtggccccatgcagcg ggtctggtatgtggctcccagtgcgccttcctaagaagctcccctgttgcgctggtgctg ctggtcggggggccctggctgggggcggagttgggggcacttgccccagttagactgctg gagcagatgggcaaggacagaggtgtgcttgccttgacctggttgtctcagaccctgaat gacgagggggaggagaggagggaaggggtacagaccacagtgaacaccgagtacgccttg ctgaaatctgattctcatcagaaaaacagcctgagaacacaccaccttgtactgcctctg gtggagcaggcaggaaaaacccgggctggactgaggagggccctgggaggcggttctcgc agcaagcgaaacagtgagctggggcttgtgcctccaggcctgaaagaatccaaggccttt cggataaagtag

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