Bison bison bison (American bison): 104982944 Help Entry 104982944         CDS       T08726                                  Symbol TRAF2 Name (RefSeq) TNF receptor-associated factor 2   KO K03173   TNF receptor-associated factor 2 [EC:2.3.2.27] Organism bbis  Bison bison bison (American bison) Pathway bbis04010   MAPK signaling pathway bbis04064   NF-kappa B signaling pathway bbis04071   Sphingolipid signaling pathway bbis04137   Mitophagy - animal bbis04141   Protein processing in endoplasmic reticulum bbis04210   Apoptosis bbis04217   Necroptosis bbis04380   Osteoclast differentiation bbis04621   NOD-like receptor signaling pathway bbis04622   RIG-I-like receptor signaling pathway bbis04657   IL-17 signaling pathway bbis04668   TNF signaling pathway bbis04920   Adipocytokine signaling pathway bbis04932   Non-alcoholic fatty liver disease bbis05010   Alzheimer disease bbis05014   Amyotrophic lateral sclerosis bbis05016   Huntington disease bbis05017   Spinocerebellar ataxia bbis05022   Pathways of neurodegeneration - multiple diseases bbis05132   Salmonella infection bbis05135   Yersinia infection bbis05160   Hepatitis C bbis05163   Human cytomegalovirus infection bbis05167   Kaposi sarcoma-associated herpesvirus infection bbis05168   Herpes simplex virus 1 infection bbis05169   Epstein-Barr virus infection bbis05170   Human immunodeficiency virus 1 infection bbis05200   Pathways in cancer bbis05203   Viral carcinogenesis bbis05222   Small cell lung cancer bbis05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:bbis00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     104982944 (TRAF2)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104982944 (TRAF2)    04064 NF-kappa B signaling pathway     104982944 (TRAF2)    04668 TNF signaling pathway     104982944 (TRAF2)    04071 Sphingolipid signaling pathway     104982944 (TRAF2)  09140 Cellular Processes   09141 Transport and catabolism    04137 Mitophagy - animal     104982944 (TRAF2)   09143 Cell growth and death    04210 Apoptosis     104982944 (TRAF2)    04217 Necroptosis     104982944 (TRAF2)  09150 Organismal Systems   09151 Immune system    04621 NOD-like receptor signaling pathway     104982944 (TRAF2)    04622 RIG-I-like receptor signaling pathway     104982944 (TRAF2)    04657 IL-17 signaling pathway     104982944 (TRAF2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     104982944 (TRAF2)   09158 Development and regeneration    04380 Osteoclast differentiation     104982944 (TRAF2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     104982944 (TRAF2)    05203 Viral carcinogenesis     104982944 (TRAF2)   09162 Cancer: specific types    05222 Small cell lung cancer     104982944 (TRAF2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     104982944 (TRAF2)    05160 Hepatitis C     104982944 (TRAF2)    05168 Herpes simplex virus 1 infection     104982944 (TRAF2)    05163 Human cytomegalovirus infection     104982944 (TRAF2)    05167 Kaposi sarcoma-associated herpesvirus infection     104982944 (TRAF2)    05169 Epstein-Barr virus infection     104982944 (TRAF2)   09171 Infectious disease: bacterial    05132 Salmonella infection     104982944 (TRAF2)    05135 Yersinia infection     104982944 (TRAF2)   09164 Neurodegenerative disease    05010 Alzheimer disease     104982944 (TRAF2)    05014 Amyotrophic lateral sclerosis     104982944 (TRAF2)    05016 Huntington disease     104982944 (TRAF2)    05017 Spinocerebellar ataxia     104982944 (TRAF2)    05022 Pathways of neurodegeneration - multiple diseases     104982944 (TRAF2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     104982944 (TRAF2)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     104982944 (TRAF2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:bbis03019]     104982944 (TRAF2)    04121 Ubiquitin system [BR:bbis04121]     104982944 (TRAF2) Enzymes [BR:bbis01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      104982944 (TRAF2) Messenger RNA biogenesis [BR:bbis03019]  Eukaryotic type   mRNA surveillance and transport factors    mRNA cycle factors     Stress granule specific factors      104982944 (TRAF2) Ubiquitin system [BR:bbis04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     104982944 (TRAF2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TRAF-mep_MATH MATH_2 TRAF_BIRC3_bd zf-TRAF TRAF2_zf zf-C3HC4 TRAF3_RING zf-RING_6 zf-C3HC4_2 zf-C3HC4_4 zf-RING_4 Motif Other DBs NCBI-GeneID:  104982944 NCBI-ProteinID:  XP_010830985 Ensembl:  ENSBBBG00000024704 UniProt:  A0A6P3GX47 LinkDB All DBs Position Unknown AA seq 516 aa AA seqDB search MAAASVTPPGSLDLLQPGFSKTLLGTKLEDKYLCSACKNVLRRPFQAQCGHRYCSFCLSS ILSSGPQSCAACVHEGIYEEGVSILESSSAFPDNAARREVESLPAVCPSEGCSWKGTLKD YESCHEGQCPFMLTECPACKGLVRLGEKEHHLEHQCPERSLSCRHCRAPCSPADMKAHHQ ICPKFPLTCDGCGKKKIAREKFQDHVRACGRCRVPCRFHAVGCPEMVESEQQPEHEAQRL QEHLALLLGVLLEAGRPPGDSRLLLRPGEGALEAGTPSRVAELLQRCEALERKTATFENI VCVLNREVERVAVTAEACGRQHRLDQDRIEALSNKVQQLERSIGLKDLAMADLEQKVLEM EASTFDGVFIWKISDFSRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRAYLNGDGTGRGT HLSLFFVLMRGPHDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVGDMNI ASGCPLFCPVSKMETKNSYVRDDAIFIKAIVDLTGL NT seq 1551 nt NT seq  +upstreamnt  +downstreamnt atggctgcagccagcgtgacccctcccggctccctggacctactgcagcccggcttctcc aagactctcctggggaccaagctagaggacaagtacctgtgctcggcctgcaagaacgtg ctgcgcagacccttccaggctcagtgtggccatcgctactgctccttctgcctgagcagc atcctgagctccgggccccagagctgcgccgcctgcgtgcacgagggcatttacgaggag ggcgtctcaatcctggagagcagctcggcgttcccggacaatgctgcccgcagggaggtg gagagcctgccggccgtctgccccagcgagggctgctcctggaaggggaccctgaaggac tacgagagctgccacgaaggacagtgcccgttcatgctgaccgagtgcccggcgtgcaaa ggcctcgtgcgcctgggcgagaaggagcaccacctggagcaccagtgcccggagcggagc ctcagctgccggcactgcagggcgccctgctcccctgccgacatgaaggcgcaccaccag atctgccccaagttccccttgacgtgcgacggctgcggcaagaagaagatcgcccgtgag aagtttcaggaccacgtccgggcgtgtggcagatgccgagtcccgtgccgattccacgct gttggctgccccgagatggtggagagcgagcagcagccggagcacgaggcgcagcggctc caggagcacctggccctgctgctgggcgtcctgctggaggctgggcggcccccgggggac agccgcctgctcctcaggccaggcgagggcgccttggaggccggcacaccctccagggtg gcggagctgctgcagaggtgcgaggccctggagcggaagacagccaccttcgagaacatc gtctgtgtgctgaaccgggaggtggagcgggtggccgtgacggctgaggcctgcggccgg cagcaccggctggaccaagacaggatcgaggccctgagcaacaaggtacagcagctggag aggagcatcggcctgaaggacctggccatggccgacctggagcagaaggtcctcgagatg gaggcgtccacctttgacggcgtgttcatctggaagatctcggacttctccaggaagcgc caggaagccgtggccggccgcacgcccgccatcttctccccagccttctacaccagcagg tacggctacaagatgtgcctgcgcgcctacctcaacggggacggcacggggcgcggcacg cacctgtccctcttcttcgtgctaatgcgtggcccgcacgacgccctcctgcgctggccc ttcaaccagaaggtgaccctgatgctgctggaccagaacaaccgggagcacgtgatcgac gccttcaggcccgacgtgacctcatcctccttccagaggccggtcggcgacatgaacatc gccagcggctgcccgctcttctgccctgtctccaagatggagaccaagaactcctacgtg cgtgacgacgccatctttatcaaggccattgtggacctgaccgggctctag

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