Bison bison bison (American bison): 104987508
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Entry
104987508 CDS
T08726
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis00562
Inositol phosphate metabolism
bbis01100
Metabolic pathways
bbis01521
EGFR tyrosine kinase inhibitor resistance
bbis04068
FoxO signaling pathway
bbis04070
Phosphatidylinositol signaling system
bbis04071
Sphingolipid signaling pathway
bbis04115
p53 signaling pathway
bbis04140
Autophagy - animal
bbis04150
mTOR signaling pathway
bbis04151
PI3K-Akt signaling pathway
bbis04218
Cellular senescence
bbis04510
Focal adhesion
bbis04931
Insulin resistance
bbis05165
Human papillomavirus infection
bbis05166
Human T-cell leukemia virus 1 infection
bbis05200
Pathways in cancer
bbis05206
MicroRNAs in cancer
bbis05208
Chemical carcinogenesis - reactive oxygen species
bbis05213
Endometrial cancer
bbis05214
Glioma
bbis05215
Prostate cancer
bbis05218
Melanoma
bbis05222
Small cell lung cancer
bbis05224
Breast cancer
bbis05225
Hepatocellular carcinoma
bbis05230
Central carbon metabolism in cancer
bbis05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
bbis05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
104987508 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
104987508 (PTEN)
04070 Phosphatidylinositol signaling system
104987508 (PTEN)
04071 Sphingolipid signaling pathway
104987508 (PTEN)
04151 PI3K-Akt signaling pathway
104987508 (PTEN)
04150 mTOR signaling pathway
104987508 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
104987508 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
104987508 (PTEN)
04218 Cellular senescence
104987508 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
104987508 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
104987508 (PTEN)
05206 MicroRNAs in cancer
104987508 (PTEN)
05208 Chemical carcinogenesis - reactive oxygen species
104987508 (PTEN)
05230 Central carbon metabolism in cancer
104987508 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
104987508 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
104987508 (PTEN)
05214 Glioma
104987508 (PTEN)
05218 Melanoma
104987508 (PTEN)
05215 Prostate cancer
104987508 (PTEN)
05213 Endometrial cancer
104987508 (PTEN)
05224 Breast cancer
104987508 (PTEN)
05222 Small cell lung cancer
104987508 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
104987508 (PTEN)
05165 Human papillomavirus infection
104987508 (PTEN)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
104987508 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
104987508 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
104987508 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
bbis01009
]
104987508 (PTEN)
Enzymes [BR:
bbis01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
104987508 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
104987508 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
104987508 (PTEN)
Protein phosphatases and associated proteins [BR:
bbis01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
104987508 (PTEN)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PTEN_C2
Tc-R-P
PTP-SAK
DSPc
PTP-NADK
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
104987508
NCBI-ProteinID:
XP_010836780
Ensembl:
ENSBBBG00000012626
UniProt:
A0A6P3HDY6
LinkDB
All DBs
Position
Unknown
AA seq
403 aa
AA seq
DB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEESSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1212 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatgggctttcctgcagaa
agacttgaaggtgtatacaggaacaatatagatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctatgtgctgaaagacattatgataccgccaaa
tttaattgcagagttgcacagtatccctttgaagaccataatccaccacagttagaactt
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttgtta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcatctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggtggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggacccacacgacgggaagacaagttcatgtac
tttgagttccctcagccattgcctgtgtgtggtgacatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaacacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagtatttgcagtatagagcgtgcagataatgacaaggaatatctagtactcacttta
acaaaaaatgatctcgacaaagcaaataaagacaaggccaaccgatacttttctccaaat
tttaaggtgaagctgtacttcacaaaaacagtagaggagtcatcaaatccagaggctagc
agttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcatacacaaatt
acaaaagtctga
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integrated database retrieval system
