KEGG   Bison bison bison (American bison): 104989128
Entry
104989128         CDS       T08726                                 
Symbol
CAD
Name
(RefSeq) LOW QUALITY PROTEIN: CAD protein
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis00220  Arginine biosynthesis
bbis00240  Pyrimidine metabolism
bbis00250  Alanine, aspartate and glutamate metabolism
bbis01100  Metabolic pathways
bbis01240  Biosynthesis of cofactors
Module
bbis_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    104989128 (CAD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    104989128 (CAD)
   00220 Arginine biosynthesis
    104989128 (CAD)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:bbis01002]
    104989128 (CAD)
Enzymes [BR:bbis01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     104989128 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     104989128 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     104989128 (CAD)
Peptidases and inhibitors [BR:bbis01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   104989128 (CAD)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   104989128 (CAD)
SSDB
Motif
Pfam: CPSase_L_D2 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 ATP-grasp MGS Dala_Dala_lig_C Amidohydro_1 ATPgrasp_Ter ATP-grasp_3 Peptidase_C26 GARS_A
Other DBs
NCBI-GeneID: 104989128
NCBI-ProteinID: XP_010838996
Ensembl: ENSBBBG00000016602
UniProt: A0A6P3HA19
LinkDB
Position
Unknown
AA seq 2250 aa
MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GIPPDEVDEFGLSKWFESSGIHVAGLVVGECCPTPSHWSASCTLHEWLQQHGIPGLQGVD
TRELTKKLREQGSLLGKLVQDGTEPSTLPFLDPNARPLVPEVSTKVPQVFNAGGTPRILA
LDCGLKYNQVRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPNLVSTLSRVL
SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE
TDSLPASWLPLFTNANDHSNEGIVHESLPFFSVQFHPEHQAGPSDMELLFDIFLETVKET
AAGNPGGQTVRERLAERLCLLGIPTPGSGLTAPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQT
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFASRMAEIGEHVAPSEAANSLEQ
AQAAAERLGYPVLVRAAYALGGLGSGFASNKEELSALVAPAFAHTSQVLVDKSLKGWKEI
EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRM
KRIIAHTQLLEQHRGQPLPPDLLHQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKVGRCRXV
SEGSLSATAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNL
QLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMREEVEPVGLMTGSGVVGV
KVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGS
YKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGESPPQRSIL
EQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALG
QIGPAPPLKAHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGVTMVC
AMPNTRPPITDAPALALAQKLAEAGARCDYALFLGASSENAGTLGTVAGSAAGLKLYLNE
TFSKLRLDSVAQWMEVGGEWGRGQPASAPGLRASSRQVIRMVLGGRGGSARLPRDFPGGE
VGCGDCAGQGFEGLPPPRGLPALPQILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGP
GKGEVRPKLGSREDVEALWENMAIIDCFASDHAPHTVEEKCGPRPPPGFPGLETMLPLLL
TAVSEGRLSLDDVLQRLHHNPRRIFHLPPQEDTYVEVDLEHEWTVPSHMPFSKAHWTPFE
GHKVKGTIRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQGAVPQLTPSAPAASELTTTPE
RPRRSGPALPDGRFHLPPRIHRASDPGLPAEEPKEKTSRKAAEPELMGTLDGICYPPPPV
PRQASPQNLGTPGLLHPQTSPLLHSLVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKER
SLDILKGKVMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMS
CYADVVVLRHPQPGAVELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTI
TMVGDLKHGRTVHSLACLLTQYRVSLRYVAPPSLRMPPDVRAFVASRGTKQEEFESIEEA
LPDTDVLYMTRIQKERFGSTQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEV
DSDPRAAYFRQAENGMYIRMALLATVLGRF
NT seq 6753 nt   +upstreamnt  +downstreamnt
atggccgccctggtgttggaggacgggtcggtcctgcggggccagccctttggggccgct
gtgtcgactgccggggaagtggtgtttcaaaccggtatggtcggctaccccgaggccctg
actgacccttcctacaaagcacagatcttagtgctgacataccctctgatcggtaactac
ggaatccccccggatgaagtggatgagttcgggctcagcaagtggtttgaatcctcgggg
atccacgtggcaggactggtggtgggagagtgctgtcccacacccagccactggagtgcc
agctgcactctgcacgagtggctgcaacaacatggcataccaggcctgcaaggagtggac
actcgggagctgactaagaagctgcgagagcaagggtctctgctgggcaagttggtccag
gatgggacagaaccttcaaccctgcccttcttggaccccaatgcccgccccctggtgcca
gaggtctccactaaggttccccaggtattcaacgcagggggtacccctcggatccttgct
ttggactgtggcctcaagtataatcaggtccgatgcttgtgccagcgtggggcagaggtc
actgtggtaccctgggaccacgcgttagacagtcaagagtatgagggtctcttcctgagt
aatggccctggtgaccctgcctcctatcccaacttggtatccacactgagccgtgtttta
tctgaaccaaacccccgacctgtcttcgggatctgtctgggacaccagcttttggcctta
gccattggggccaagacttacaagatgagatatgggaaccgaggccataaccagccatgc
ttgctggtgggctccgggcgctgctttctaacatcccagaaccatggatttgctgtggaa
acagactcgctgccagcaagctggcttcctctcttcaccaatgccaatgatcactccaac
gaaggcatcgtacatgagagcctgcccttcttcagtgtccagtttcacccagagcatcaa
gctggcccttcagatatggaacttctttttgacatttttctggaaactgtgaaagaaact
gcagctggaaaccctgggggccagacagttcgagagcggctggctgagcgcctctgtctc
cttgggattcccaccccaggctctgggcttacagcaccacgaaaggttctgattctgggc
tcagggggcctctccatcggccaggccggcgagtttgactactcaggctctcaggcgatc
aaggccctgaaggaggaaaacattcagacattgctgatcaaccctaacatcgctaccgtg
cagacctcacaggggctggcggacaaggtctatttcctccccataacacctcactacgta
acccaggtgatacgtaatgagcgcccagatggtgtgttactgacttttgggggccaaaca
gctctgaactgtggtgtggagctgaccaaggctggggtgcttgctcggtacggagtccgg
gtcctgggcacacccgtggagaccattgagttgactgaagatcggcgtgccttcgcctcc
aggatggcagagatcggagagcatgtggcccccagcgaggcagcgaattctcttgagcag
gcccaggcagctgctgagagactgggataccctgtgctggtgcgcgcagcctatgccttg
ggtggcctgggctctggctttgcctctaacaaagaggagttgtctgctctcgtggcccca
gcttttgcccataccagccaagtgctggtagataagtccctgaaaggatggaaggagatt
gagtatgaggtggtgagagatgcctatggcaactgtgtcacggtgtgtaacatggagaac
ctagacccgctgggcatccacaccggggagtccatcgtggtggctccaagccagacgcta
aatgacagggagtaccagctgctgaggcagacggccatcaaggtgactcagcacctcgga
atcgtcggggagtgcaacgtgcagtacgccctgaaccctgagtctgagcagtactacatc
attgaagtgaatgccaggctctctcgcagctctgccctagccagtaaggccacaggctac
ccactggcctatgtggcagccaagctggctttgggcatccctctgcctgaactcaggaac
tctgtgacagggggaacggcagcctttgaacccagtctggattactgtgtggtgaagatt
cctcgctgggacctcagcaagttcctccgcgtcagcacaaagattgggagctgcatgaag
agcgtgggtgaagtcatgggcattgggcgttcttttgaggaggccttccagaaggctctg
cgcatggtggatgagaactgcgtgggctttgatcacacggtcaagcccgtcagtgatatg
gagttagagactccaacagacaagcgcatcttcgtggtggcagcagccctatgggctggc
tactcagtggatcgcctgtatgaactcactcgcatcgaccgctggttcctgcaccggatg
aagcggatcatagcacacacccagctgctagagcaacaccgtggacaacctttgccccca
gacctgctgcatcaggccaagtgccttggcttctcagacaagcagattgccctcgcggtc
ctcagcacagagctggctgttcgcaagctgcgtcaggaactagggatctgcccagcagtg
aagcagattgacacggttgcagctgagtggccggcccagacaaattacttgtacctgaca
tactggggcaccacccatgacctcacctttcgaacaccccatgtcctagtccttggctct
ggcgtctaccgtatcggctccagcgtcgagtttgactggtgtgccgtgggctgtatccag
cagctgcgaaagatggggtataagaccatcatggtgaactacaacccagagacagtcagc
accgactacgacatgtgtgaccgactctacttcgatgaaatctcttttgaggtggtgatg
gacatctatgagctggaaaaccctgaaggtgtgatcttgtccatgggcgggcagctgccc
aacaacatggccatggctttgcatcggcaacagtgtcgggttctgggcacctccccagaa
gccattgactcagctgagaaccgttttaagttctcccggctcctggacaccattggtatc
agccagcctcagtggagggagctcagtgacctagagtctgctcgccagttctgccagacc
gtggggtacccctgtgtcgtgcgcccctcctatgtgctgagtggtgctgctatgaacgtg
gcctacaccgatggggacttggagcgcttcttgagcagtgcagcagctgtctccaaggag
caccccgtggtcatctccaagttcatccaggaggccaaggtgggacgctgcagatgagtc
tctgaaggcagtctttcagccacggccatctccgaacacgtggagaatgcaggtgtgcat
tcaggtgatgccacactggtgaccccaccgcaggacatcactgccaaaaccctggagcgg
atcaaagccattgtgcatgccgtgggccaggagctgcaggtcacaggacccttcaatctg
cagctcattgccaaggacgaccagctgaaagtcattgaatgcaacgtgcgtgtgtctcgc
tccttccccttcgtctccaagacactaggtgtggacctagtagccttggcgacacgggtc
atcatgagggaagaagtggagcctgtgggactcatgactggctctggagttgtgggggtg
aaggtgccccagttctcgttctcccgcctggcgggggctgacgtggtgctgggtgtggag
atgaccagtactggggaagtagctggctttggggagagccgctgcgaagcctacctcaag
gccatgctcagtactggttttaagatccccaagaagaacatcttgctgaccattggcagc
tataagaacaaaagtgagttgctcccaactgtgaggctgctggagagcctgggctacagc
ctctacgccagtctgggcaccgctgacttctacacagagcatggtgtcaaggtgacggct
gtggactggcattttgaagaggcagtggatggagagtccccaccacagcgaagcattttg
gagcagcttgctgagaaaaactttgaactcgtaattaacctgtccatgcgtggggccggg
ggccggcgtctttcttccttcgtcaccaagggctaccggacacggcgcctggccgctgac
ttctccgtacccctcattattgatatcaagtgcaccaaactgtttgtggaggcgctggga
cagattgggccagcccctcctctgaaggcgcatgttgactgcatgacctcccagaagctc
gtgcggctgcctggattgattgacgtccatgtgcacctgcgggaaccaggggggacacac
aaggaggactttgcctcgggcacagctgctgccctggccgggggcgtcaccatggtgtgc
gctatgcccaatacccggccccccatcactgatgcccctgccctggccctggcgcagaag
ctggcagaggccggcgcccgctgtgactatgccttattcctcggagcctcgtcggaaaat
gcagggaccctgggcactgtggctgggtctgctgcggggctgaagctctacctcaacgag
accttctctaaactgcggctggacagtgtggcccagtggatggaggtagggggtgaatgg
gggcggggccagccagccagtgcccctggtttgagggcctcctcacggcaggtgatcagg
atggtccttgggggcaggggcggctcagcacgcctgccccgtgactttccaggaggggag
gttggatgcggggactgtgcaggtcagggcttcgagggactccccccacctcgaggtctc
cccgctctcccccagatcctgctgattaaagcggctaaggcgcgggggctgccggtgacc
tgtgaggtggcaccccaccatctgttcctgagccatgatgacctggagcgtctggggccc
gggaagggggaggttcggcccaagcttggctcccgggaggacgtggaagccctatgggag
aacatggccatcatcgactgctttgcctccgaccacgccccccacaccgtggaggagaag
tgtgggccccggcctccccccggcttcccagggctggagaccatgctgcccctgctgctg
acggcagtgagcgagggccggctcagcctggacgacgtgctgcagcgactgcaccacaac
cctcggcgcatcttccacctgccccctcaggaggacacctatgtggaggtggatctggag
cacgaatggacagtccccagccacatgcccttctccaaggcccactggacaccctttgaa
gggcataaggtgaagggcaccatccgccgtgtggtcctgcgtggggaggtggcctatatt
gacgggcaggtgctggtgccacccggctatggacaggacgtccgcaagtggccccagggt
gctgttccacagctcacgccctcggccccggctgccagtgagctaaccacgaccccggag
aggccccgccggagcggcccagcactccctgatggccgcttccacctgcctccccggatc
caccgagcctctgacccaggtttgccagctgaggagccaaaggagaagacctcccgcaag
gcagctgagccagagctgatgggaacccttgatggcatctgctaccctccaccaccagta
cctagacaggcgtcaccccagaacctggggacccctggcctgctgcacccccagacctca
cccctgctgcactcactagtgggccaacatatcctgtccgtccagcagttcaccaaggat
cagatgtctcacctgttcaacgtggcacacacgctgcgcatgatggtacagaaggagcgg
agcctcgacatcctcaaggggaaggtgatggcctccatgttctacgaggtgagcacacgg
accagcagctcctttgcagcagccatggcccggctcgggggcgctgtgctcagcttctcc
gaagccacgtcctccgtccagaagggcgagtccctggctgactcggtgcagaccatgagc
tgctacgctgatgtcgttgtgctgcggcacccccagcccggggcagtggagctggcagcc
aagcactgccggaggccagtgatcaacgcaggggacggggttggagagcaccctacccag
gccttgctggacatcttcaccatccgggaggagcttgggacggtcaatggcatgacgatc
acgatggtgggcgacctgaagcatggccgcacagtgcattcgctggcctgcctgctcacc
cagtaccgtgtcagcctgcgctacgtggcgcccccaagcctgcgcatgccccctgacgtg
cgggccttcgtggcctcccgtggcaccaagcaggaggaatttgagagcatcgaggaggcg
ctgcctgacaccgatgtactctacatgacacgcatccagaaggagcgcttcggctccacc
caggagtatgaagcatgcttcggccagttcatcctcactccgcacatcatgacccgggcc
aagaagaagatggtggtgatgcacccaatgccccgtgtcaatgagatcagtgtggaggtg
gactcagacccccgagcagcctacttccgccaggcagagaacggcatgtacatccgcatg
gctctgttggccaccgtgctgggccgcttctag

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