Bison bison bison (American bison): 104991715
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Entry
104991715 CDS
T08726
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis01524
Platinum drug resistance
bbis04010
MAPK signaling pathway
bbis04071
Sphingolipid signaling pathway
bbis04141
Protein processing in endoplasmic reticulum
bbis04210
Apoptosis
bbis04530
Tight junction
bbis04668
TNF signaling pathway
bbis04714
Thermogenesis
bbis04722
Neurotrophin signaling pathway
bbis04932
Non-alcoholic fatty liver disease
bbis04936
Alcoholic liver disease
bbis05010
Alzheimer disease
bbis05012
Parkinson disease
bbis05014
Amyotrophic lateral sclerosis
bbis05016
Huntington disease
bbis05017
Spinocerebellar ataxia
bbis05022
Pathways of neurodegeneration - multiple diseases
bbis05208
Chemical carcinogenesis - reactive oxygen species
bbis05417
Lipid and atherosclerosis
bbis05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
104991715 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
104991715 (MAP3K5)
04668 TNF signaling pathway
104991715 (MAP3K5)
04071 Sphingolipid signaling pathway
104991715 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
104991715 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
104991715 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
104991715 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
104991715 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
104991715 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
104991715 (MAP3K5)
05012 Parkinson disease
104991715 (MAP3K5)
05014 Amyotrophic lateral sclerosis
104991715 (MAP3K5)
05016 Huntington disease
104991715 (MAP3K5)
05017 Spinocerebellar ataxia
104991715 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
104991715 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
104991715 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
104991715 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
104991715 (MAP3K5)
04932 Non-alcoholic fatty liver disease
104991715 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
104991715 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbis01001
]
104991715 (MAP3K5)
Enzymes [BR:
bbis01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
104991715 (MAP3K5)
Protein kinases [BR:
bbis01001
]
Serine/threonine kinases: STE group
STE11 family
104991715 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
104991715
NCBI-ProteinID:
XP_010842606
Ensembl:
ENSBBBG00000025426
UniProt:
A0A6P3HJT1
LinkDB
All DBs
Position
Unknown
AA seq
1491 aa
AA seq
DB search
MGPDSIAELGRHRPEEGAVVTGNVARASWRWLRRPEYSQERLFWGPSYSRVRSGLLPTPG
YLGWGAQWVTEENLGLARCSGLGCGPGAATRSVSSGLELPSSALPRGGPRLSVPRRVGGK
KPVADLARAGTALPGGQGASHPESGALEPHRLAGSRADLSAGQEKEALSLPAQPASPPLP
GAGCPSATSGSSATRCRGNSGGGGGRRTTVAYVINEASQGQLVVAESEALQCLREACETV
GAALETLHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIIL
YCDTNSDSLQSLKEIICQKNTMCTGNYTFIPYMITPHSKVYCCDSSFMKGLTELMQPNFE
LLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRV
DNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRN
LPGDRAKALDIMIPLVQNEEQVASDMYCLVGRIYKDMFLDSNFMDTESRDHGASWFKKAF
ESEPTLQSGINYAVLLLASGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLG
ASVLANDHLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTSEQPVAKQELVDFWM
DFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWN
FSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGKNTEE
GDCEGDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLH
EEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFY
TKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTL
QYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEI
PESMSAEAKAFILKCFEPDPDKRDCANDLLMDEFLKVSSKKKKTQPKLSALSAGSNEYLR
SISLPVPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKDVKGIRTLFLGIPDE
NFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLK
WEHITTLVASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLR
NHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEGDHDERPS
NQTVRRPHAVLEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELVQKE
KELQALLHQAIEEKDQEIKHLKLKSQPIDVPGLPGCHSSSPGTNTEDSELTDWLRENGAD
EDTISRFLAEDYSLMDVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDKQA
NT seq
4476 nt
NT seq
+upstream
nt +downstream
nt
atgggacccgacagcatcgcggagctaggccggcacaggccggaggagggcgccgtggtt
acggggaacgtggcgcgtgcctcctggcgctggctgagaagacccgagtattcgcaagag
agacttttttgggggccatcctatagtcgcgtgcgctccgggcttttgcctactccaggt
tatcttgggtggggagcccagtgggtgacggaggagaaccttggcctcgcgcggtgctcc
gggctgggctgcggtccgggagccgcgacgcggtcggtttcgtccggactcgagcttccc
agcagcgccctcccccggggcgggcccagactttcagtgccgcgacgagtgggcggcaaa
aagccggtggcggacctggcgagagccgggaccgcgctccccgggggccagggtgcatcg
cacccggagagcggcgcccttgagccgcaccgcctagcaggttcgcgagccgacttgtcc
gccggccaagaaaaggaagcgctgtcccttcccgctcagccggcctccccaccccttccc
ggcgccgggtgtcccagtgccacctccgggagcagcgccacccggtgccggggcaactct
gggggcggaggcggccgacggaccacggtggcctatgtcatcaacgaagcgagccagggg
cagctggtggtggccgagagcgaggccctgcagtgcctgcgggaggcgtgcgagacggtg
ggcgccgccctggagaccctgcattttgggaaactggactttggggaaactgcggtgctg
gaccgattttacaatgcagatatcgccgtggtggagatgagtgatgccttccgacaacca
tccttattttaccaccttggagtgagagaaagtttcagcatggccaacaacatcatcctc
tactgtgatactaattcagactctctgcagtcactgaaggagatcatttgccagaagaat
actatgtgcactggaaactacacgtttatcccttacatgataacgccgcacagcaaggtc
tactgctgtgacagcagcttcatgaagggcttgactgagctcatgcagccgaactttgag
ctgcttctgggacccatctgcttacctctcgtggatcgtttcattcagcttttgaaggtg
gcacaagcaagttccagccagtatttccgggagtctatactcaacgatatcaggaaagct
cgtaacttatatactggcaaagaattggcagctgaattggcaagaattcgacagcgagtg
gataatattgaagtcttgacagcagatattgtcataaatctgttactttcatatagagat
atccaggactatgattctattgtgaagctggtagagactttagaaaagcttccaacgttt
gatttggcctcccatcaccatgtgaagtttcattatgcctttgcactgaataggagaaac
ctccctggagatagagcaaaagctcttgacattatgattcccctggtgcaaaatgaagag
caggttgcttcagatatgtattgcctcgttggtcgaatctacaaagatatgtttttggac
tctaatttcatggacactgaaagcagagaccatggagcttcttggttcaaaaaggcattt
gaatcagagccaacactacagtcaggaattaattatgcggtcctcctcctggcatctggg
caccagtttgaatcttcctttgagctccgaaaagttggggtgaagctaagtagtcttctt
ggtaaaaagggaaacttggaaaaactccagagctactgggaagttggatttttcctgggg
gccagtgtcctggccaatgaccacttgagagtcattcaagcatctgaaaagctttttaaa
ctgaagacacctgcatggtacctcaagtctatcgtagagacaattttgatatataagcat
tttgtgaaactgacttcggaacagcctgtggccaaacaggaacttgtggacttctggatg
gatttcctggtcgaggccacaaagacagatgtcactgtagttaggtttccagtattaata
ttagaaccaaccaaaatctatcaaccttcgtatttgtctatcaacaatgaagttgaggag
aagacaatatctatttggcacgtgcttcctgatgacaagaaaggtatacatgagtggaat
tttagtgcttcttctgtcaggggtgtgagtatttctaaatttgaagaacgatgctgtttt
ctgtacgtgcttcacaattctgacgatttccaaatctacttctgtacagaacttcactgt
aaaaagttttttgaaatggtgaacaccattactgaagagaaggggaaaaacacagaggaa
ggagattgtgaaggtgactccctggagtatgactatgaatacgatgaaaatggtgacaga
gtcgttttaggaaaaggcacttatgggatagtttatgcaggtcgagatctgagcaaccaa
gtcagaatcgccattaaggaaatcccagagagagacagcagatactcccagcccctgcat
gaagaaatagccttgcataagcatctgaagcacaaaaatattgtccagtatctgggctct
ttcagtgaaaatggtttcattaaaatcttcatggagcaggtcccaggaggaagtctttct
gctctccttcgttccaaatggggcccactgaaagacaatgagcaaacaattggcttttat
acaaagcaaatactggaaggattaaaatacctccatgataatcagatagttcaccgggat
ataaagggtgacaatgtgttgattaatacctacagtggtgttctcaagatttctgatttc
ggaacatcaaagaggcttgctggcataaatccatgtactgaaacttttactggtaccctc
cagtatatggcaccagaaataatagataaaggaccaagaggctatggaaaggcagcagac
atttggtctctgggctgcacgatcattgaaatggccactggaaaaccacccttttatgaa
ctgggggaaccacaagcagctatgttcaaggtggggatgtttaaagtccacccagagatc
ccagagtccatgtcagcagaggccaaggcgttcatattgaagtgtttcgaaccagaccct
gacaagagagactgtgctaacgacttgcttatggatgagttcttaaaagtttcaagcaaa
aagaaaaagacacaacctaagctttcagctctttcagctggatcgaatgagtacctcagg
agtatctccttgccagtgccagtcctggtggaggacacgagcagcagcagcgagtacggc
tcagtttcccctgacacagagttgaaggtggaccccttctctttcaaaacaagagccaag
tcctgtggagaaaaggatgtcaaaggcatccggacgctgtttctgggcatccctgatgaa
aattttgaagaccacagtgctccaccttctccagaagaaaaagattccggattctttatg
ctgaggaaggacagtgagagacgggccacgcttcacaggattctgacggaagaccaagac
aaagttgtgagaaacttaatggaatccttggctcagggggctgaagaacctaaactgaaa
tgggaacacatcacaactctggtcgcaagcctcagagaatttgtgaggtccacggaccgg
aagatcatagccaccaccctgtccaagctgaagctggagctggacttcgacagccacggg
atcagtcaggtccaggtggtgctctttggtttccaagatgctgtcaataaagttcttcgg
aatcataacatcaagccacactggatgtttgccttagacagtatcatccgaaaggcggta
cagacagctattaccattctggttccagaactgaggccgcatttcagccttgcatctgag
agtgatactgccgatcaagaagacttggatgcagaaggtgaccatgacgaacggccttca
aatcaaactgtccgaagacctcatgccgtccttgaagacgcggtggccacctcaggggtg
agcacgctcagttctactgtatcccatgactcccagagtgctcaccgatcactgaatgta
cagcttggaaggatgaaaatagaaacaaatagattactggaagaattggttcagaaagag
aaagaattacaagcactccttcatcaagctattgaagagaaagaccaagaaattaaacac
ctgaagcttaagtcccaaccaatagatgttcctgggttgcctgggtgtcactccagttct
cctggcacaaacactgaagattcggaacttactgactggctgagagagaacggagccgat
gaagacactataagtcggtttttggctgaggattattcattaatggatgttctctactat
gttacacgtgatgatttaaaatgcctgagactaaggggcgggatgctgtgcacactgtgg
aaagccatcactgacttccgagacaaacaggcttga
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integrated database retrieval system
