Bison bison bison (American bison): 104991731
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Entry
104991731 CDS
T08726
Symbol
ADCY8
Name
(RefSeq) LOW QUALITY PROTEIN: adenylate cyclase type 8
KO
K08048
adenylate cyclase 8 [EC:
4.6.1.1
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis00230
Purine metabolism
bbis01100
Metabolic pathways
bbis01522
Endocrine resistance
bbis04015
Rap1 signaling pathway
bbis04020
Calcium signaling pathway
bbis04022
cGMP-PKG signaling pathway
bbis04024
cAMP signaling pathway
bbis04062
Chemokine signaling pathway
bbis04072
Phospholipase D signaling pathway
bbis04114
Oocyte meiosis
bbis04211
Longevity regulating pathway
bbis04213
Longevity regulating pathway - multiple species
bbis04261
Adrenergic signaling in cardiomyocytes
bbis04270
Vascular smooth muscle contraction
bbis04371
Apelin signaling pathway
bbis04540
Gap junction
bbis04611
Platelet activation
bbis04713
Circadian entrainment
bbis04714
Thermogenesis
bbis04720
Long-term potentiation
bbis04723
Retrograde endocannabinoid signaling
bbis04724
Glutamatergic synapse
bbis04725
Cholinergic synapse
bbis04727
GABAergic synapse
bbis04742
Taste transduction
bbis04750
Inflammatory mediator regulation of TRP channels
bbis04911
Insulin secretion
bbis04912
GnRH signaling pathway
bbis04913
Ovarian steroidogenesis
bbis04914
Progesterone-mediated oocyte maturation
bbis04915
Estrogen signaling pathway
bbis04916
Melanogenesis
bbis04918
Thyroid hormone synthesis
bbis04921
Oxytocin signaling pathway
bbis04923
Regulation of lipolysis in adipocytes
bbis04925
Aldosterone synthesis and secretion
bbis04926
Relaxin signaling pathway
bbis04927
Cortisol synthesis and secretion
bbis04928
Parathyroid hormone synthesis, secretion and action
bbis04934
Cushing syndrome
bbis04935
Growth hormone synthesis, secretion and action
bbis04970
Salivary secretion
bbis04971
Gastric acid secretion
bbis04972
Pancreatic secretion
bbis04976
Bile secretion
bbis05032
Morphine addiction
bbis05163
Human cytomegalovirus infection
bbis05166
Human T-cell leukemia virus 1 infection
bbis05200
Pathways in cancer
bbis05207
Chemical carcinogenesis - receptor activation
bbis05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
104991731 (ADCY8)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
104991731 (ADCY8)
04371 Apelin signaling pathway
104991731 (ADCY8)
04020 Calcium signaling pathway
104991731 (ADCY8)
04072 Phospholipase D signaling pathway
104991731 (ADCY8)
04024 cAMP signaling pathway
104991731 (ADCY8)
04022 cGMP-PKG signaling pathway
104991731 (ADCY8)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
104991731 (ADCY8)
09144 Cellular community - eukaryotes
04540 Gap junction
104991731 (ADCY8)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
104991731 (ADCY8)
04062 Chemokine signaling pathway
104991731 (ADCY8)
09152 Endocrine system
04911 Insulin secretion
104991731 (ADCY8)
04923 Regulation of lipolysis in adipocytes
104991731 (ADCY8)
04912 GnRH signaling pathway
104991731 (ADCY8)
04913 Ovarian steroidogenesis
104991731 (ADCY8)
04915 Estrogen signaling pathway
104991731 (ADCY8)
04914 Progesterone-mediated oocyte maturation
104991731 (ADCY8)
04921 Oxytocin signaling pathway
104991731 (ADCY8)
04926 Relaxin signaling pathway
104991731 (ADCY8)
04935 Growth hormone synthesis, secretion and action
104991731 (ADCY8)
04918 Thyroid hormone synthesis
104991731 (ADCY8)
04928 Parathyroid hormone synthesis, secretion and action
104991731 (ADCY8)
04916 Melanogenesis
104991731 (ADCY8)
04925 Aldosterone synthesis and secretion
104991731 (ADCY8)
04927 Cortisol synthesis and secretion
104991731 (ADCY8)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
104991731 (ADCY8)
04270 Vascular smooth muscle contraction
104991731 (ADCY8)
09154 Digestive system
04970 Salivary secretion
104991731 (ADCY8)
04971 Gastric acid secretion
104991731 (ADCY8)
04972 Pancreatic secretion
104991731 (ADCY8)
04976 Bile secretion
104991731 (ADCY8)
09156 Nervous system
04724 Glutamatergic synapse
104991731 (ADCY8)
04727 GABAergic synapse
104991731 (ADCY8)
04725 Cholinergic synapse
104991731 (ADCY8)
04720 Long-term potentiation
104991731 (ADCY8)
04723 Retrograde endocannabinoid signaling
104991731 (ADCY8)
09157 Sensory system
04742 Taste transduction
104991731 (ADCY8)
04750 Inflammatory mediator regulation of TRP channels
104991731 (ADCY8)
09149 Aging
04211 Longevity regulating pathway
104991731 (ADCY8)
04213 Longevity regulating pathway - multiple species
104991731 (ADCY8)
09159 Environmental adaptation
04713 Circadian entrainment
104991731 (ADCY8)
04714 Thermogenesis
104991731 (ADCY8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
104991731 (ADCY8)
05207 Chemical carcinogenesis - receptor activation
104991731 (ADCY8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
104991731 (ADCY8)
05163 Human cytomegalovirus infection
104991731 (ADCY8)
09165 Substance dependence
05032 Morphine addiction
104991731 (ADCY8)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
104991731 (ADCY8)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
104991731 (ADCY8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
104991731 (ADCY8)
Enzymes [BR:
bbis01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
104991731 (ADCY8)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_cyc
Adcy_cons_dom
AC_N
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
104991731
NCBI-ProteinID:
XP_010842620
Ensembl:
ENSBBBG00000022858
UniProt:
A0A6P3HVR2
LinkDB
All DBs
Position
Unknown
AA seq
1252 aa
AA seq
DB search
MELSDVRCLSGSEELYTIHPTPPAGDSGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGG
GNGSSSKASDPGGGGPNHHHASQLSGDSALPLYALGPGEPAHGTGGPKVFPERSGSGSAS
GSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRR
KXXXXXNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSH
TYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGT
SLMQVVLQAVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEA
RLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFAD
VKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHA
HCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANK
LESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPE
DIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALH
VQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCA
FIVLLFITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWIN
ETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFT
GVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKE
ASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHV
ARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFD
ELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINK
HSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLI
LKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGL
VQSLNRQRQKQLLNENNNTGIIKSHYNRRTLLTPSGPEPGAPAEGADKSELP
NT seq
3759 nt
NT seq
+upstream
nt +downstream
nt
atggagctctccgatgtgcgctgcctgagcggcagcgaggaactgtacaccatccacccg
acgcccccggccggcgacagcgggagcggctcccggccgcagcggctgctgtggcagacg
gcggtgcggcacatcaccgagcagcgcttcatccatgggcaccgcggcggcggcggtggc
gggaacggaagctccagcaaagcctcggaccccggaggcggcggacccaaccaccaccac
gcgtcgcagctgtccggcgactcggcgctgcccctctacgcgctgggccctggggagcca
gcgcacggcaccggcggccccaaagtcttcccggaacgcagcgggagcggcagcgccagc
ggcagcggcggcgggggagacctgggcttcctgcacctcgactgcgccccgagcaactcg
gatttcttcctcaatgggggctacagctaccgaggggtcattttccccaccctgcgcaac
tccttcaagtcccgggatctggagcgcctctaccagcgctatttcctgggccagaggcgc
aaannnnnnnnnnnnnnnaacgtgctggacgtgctgaccaaactcaccctcctggttctc
cacttgagcctggcctcggcccccatggacccgctcaagggcatcctgctgggcttcttc
accggcatagaggtggtgatctgcgccctggtggtggtcagaaaggacaccacctcgcac
acatacctgcagtacagcggtgtggtcacttgggtggccatgaccacccagatcttagca
gcagggctcggctatgggctcctgggagacggcatcggctacgtgctcttcacccttttt
gccacctacagcatgctgccgctgccgctcacctgggccatcctggccggcctaggcacc
tctttgatgcaggtggtcctccaagcggtcatccccaggctggcggtcatttccatcaat
caggttgtggcccaggcagtgttattcatgtgtatgaacacagctggaatcttcatcagt
tacctgtcagaccgggcccagcgccaagccttcctggagacacggaggtgtgtggaggcc
aggctgcgcctggagacggaaaaccaaagacaggagcgacttgtgctgtccgtgcttcct
cgttttgttgtcctggagatgatcaatgacatgaccaacgtggaagacgagcacctacag
catcagttccaccggatctacatccatcgatacgagaatgtcagtattctttttgcagat
gttaaaggatttaccaacctctccacgaccttgtctgctcaggagctggtcaggatgctc
aacgagctctttgccagatttgatcgactggcccatgagcatcactgccttcgtattaaa
atcctgggggactgctactactgcgtttcaggacttcctgagccccgccaggaccacgcc
cactgctgtgttgaaatgggcctcagcatgatcaaaactatcaggtatgtgcgatcaagg
acaaagcacgatgttgacatgcggattggaatccactcgggctcggtgctgtgcggcgtg
ttgggtcttcggaagtggcagtttgatgtctggtcttgggatgtggacatcgcgaacaaa
cttgaatctggaggaatccccgggcggattcacatttccaaagccacgctggactgcctc
aacggtgactataatgtggaagagggtcacggtaaagagaggaatgaattcttgaggaag
cataatatagagacctatttaattaagcagcctgaggagagtctgctgtctttgcctgaa
gacatcgtcaaggagtctgtgagctcctcagacaggagaaacagcggggcgacgttcaca
gagggatcttggagccctgaactgcccttcgataacatagtggggaaacagaacactctg
gctgccctaacaagaaattcaataaatctacttccaaaccatcttgcacaagctttgcat
gtccagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagt
ggtgataaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagc
ctggagcacaagtattctcaaatgagggatgaagtattcaaatcaaacttggtctgtgcg
tttatcgttcttctatttatcacggcaatacaaagcttgcttccttcttcaagggtgatg
cccatggccatccagttttccatcctgatcatgctgcactcagctctggtcctcatcact
acggcagaggattacaagtgtttgcccctagtcctccggaaaacctgctgttggattaac
gagacctatttggccaggaacgtcatcatctttgcatccatcttgattaatttcctgggc
gccatcctaaatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctgact
ttcaattcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttcacg
ggggtgctggccatggtgacctgtgcggttttcctccgactcaactctgtccttaagctg
gctgtgctcctgatcatgattgccatctacgccctgctgaccgagaccatctatgcaggc
ctctttctgcgctacgacaacctgaaccacagcggagaagatttcctggggaccaaggaa
gcgtcactgctgctaatggccatgtttcttcttgccgttttctaccatggacagcagctg
gagtacacagcccgcctggacttcctgtggcgagtccaggccaaagaggagatcaacgag
atgaaggagctgagggagcacaatgagaacatgctgcggaacatcctgcccagccacgtg
gcccgccacttcctggagaaggaccgggacaatgaggagctgtattctcaatcctatgac
gccgtcggggtgatgtttgcctccatcccggggtttgcagacttttactctcagaccgaa
atgaacaaccaaggagtggagtgcctccgcctactgaatgagatcattgctgacttcgat
gagctgcttggtgaagaccggtttcaagacattgaaaagattaagaccattggtagtacc
tacatggccgtgtcaggcctgtcacctgaaaagcagcaatgcgaggataagtgggggcat
ttgtgcgccctggccgacttctccctcgccctgactgaaagcatccaggagatcaacaag
cattccttcaacaatttcgagctccggattggcatcagccacggctcagtggtagccggt
gtcatcggcgctaagaaaccacagtacgacatttggggcaaaaccgtgaacctggcgagt
cggatggacagcacaggggtcagcggcaggatccaggtcccggaggagacctacctcatc
ctgaaggaccagggctttgcctttgactaccgaggggagatctatgtgaagggcatcagc
gaacaggaagggaaaatcaaaacgtactttctcctgggaagagtccagcccaaccccttc
atcctgccccccaggagactgcccgggcagtactccttggccgcggtcgtcctgggcctc
gtccagtctctcaacaggcagaggcagaagcagctgctgaacgagaacaacaacacgggc
attatcaagagccactacaaccggcggactttgctgacacccagcgggcccgagccggga
gccccagccgaaggcgccgacaagtccgagttgccataa
DBGET
integrated database retrieval system
