Bison bison bison (American bison): 104991966 Help Entry 104991966         CDS       T08726                                  Symbol SHC2 Name (RefSeq) SHC-transforming protein 2   KO K17447   SHC-transforming protein 2 Organism bbis  Bison bison bison (American bison) Pathway bbis01521   EGFR tyrosine kinase inhibitor resistance bbis01522   Endocrine resistance bbis04012   ErbB signaling pathway bbis04014   Ras signaling pathway bbis04062   Chemokine signaling pathway bbis04072   Phospholipase D signaling pathway bbis04370   VEGF signaling pathway bbis04510   Focal adhesion bbis04650   Natural killer cell mediated cytotoxicity bbis04722   Neurotrophin signaling pathway bbis04910   Insulin signaling pathway bbis04915   Estrogen signaling pathway bbis04917   Prolactin signaling pathway bbis04926   Relaxin signaling pathway bbis04935   Growth hormone synthesis, secretion and action bbis05034   Alcoholism bbis05100   Bacterial invasion of epithelial cells bbis05214   Glioma bbis05220   Chronic myeloid leukemia bbis05224   Breast cancer bbis05225   Hepatocellular carcinoma bbis05226   Gastric cancer Brite KEGG Orthology (KO) [BR:bbis00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     104991966 (SHC2)    04014 Ras signaling pathway     104991966 (SHC2)    04370 VEGF signaling pathway     104991966 (SHC2)    04072 Phospholipase D signaling pathway     104991966 (SHC2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     104991966 (SHC2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     104991966 (SHC2)    04062 Chemokine signaling pathway     104991966 (SHC2)   09152 Endocrine system    04910 Insulin signaling pathway     104991966 (SHC2)    04915 Estrogen signaling pathway     104991966 (SHC2)    04917 Prolactin signaling pathway     104991966 (SHC2)    04926 Relaxin signaling pathway     104991966 (SHC2)    04935 Growth hormone synthesis, secretion and action     104991966 (SHC2)   09156 Nervous system    04722 Neurotrophin signaling pathway     104991966 (SHC2)  09160 Human Diseases   09162 Cancer: specific types    05225 Hepatocellular carcinoma     104991966 (SHC2)    05226 Gastric cancer     104991966 (SHC2)    05214 Glioma     104991966 (SHC2)    05220 Chronic myeloid leukemia     104991966 (SHC2)    05224 Breast cancer     104991966 (SHC2)   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     104991966 (SHC2)   09165 Substance dependence    05034 Alcoholism     104991966 (SHC2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     104991966 (SHC2)    01522 Endocrine resistance     104991966 (SHC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PID SH2 DUF7063 DUF7145 Motif Other DBs NCBI-GeneID:  104991966 NCBI-ProteinID:  XP_010842958 UniProt:  A0A6P3HJI6 LinkDB All DBs Position Unknown AA seq 446 aa AA seqDB search MELGSAGLLLTCALSPQYMGCIEVLRSMRSLDFSTRTQVTREAINRLHEVVPGVRGSWKK KAPNKALASILGKSNLRFAGMSIAVSISIDGLNLSVPATRQIIANHHMQSISFASGGDTD MADYVAYVAKDPINQRACHILECCEGLAQSVISTVGQAFELRFKQYLHSPPRVVVPPERL TGMEDSAWGDEEEVEHSYYNSLPGKEPPPGGLVDSRLALTQPCALGVLGALGQGASPARR DARGLQWDVGPSAQPGDGYVQADARGPRDYEDHLYVNTQGLDGPESLQPEDSPKKDLFDM RKWGQAXXXXXXXXXAGSVAAPLPVEDQWPSPPTRRAPIAPTEEQLRQEPWYHGQMSRRA AEKLLRADGDFLVRDSVTNPGQYVLTGMHGGQPKHLLLVDPEGVVRTKDVLFESISHLID YHLQNGQPIVAAESELHLRGVVKREP NT seq 1341 nt NT seq  +upstreamnt  +downstreamnt atggagctgggctctgcggggctgctgctgacctgtgctctctcccctcagtacatgggc tgcatcgaggtgctccgttccatgcgctccctggacttcagcacacgcacccaggtcacc agggaagccatcaaccggctccatgaggtggtgcctggcgtccggggctcctggaagaag aaggcccccaacaaggccctggcctcaatcttgggcaagagcaacctgcgcttcgcgggc atgagcattgctgtcagcatctccatcgacggcctcaacctctccgtgcccgccacgcgc cagatcatcgccaatcatcacatgcagtccatctccttcgcgtccggtggtgacacggac atggcggattatgtggcctacgtggccaaggaccccatcaaccagagagcctgtcacatc ctggagtgctgtgagggccttgcccagagcgtcatcagcaccgtgggccaagcctttgag ctgcgcttcaaacagtacctgcacagcccccccagggtcgtcgtccccccggaaaggctg accgggatggaggactcggcctggggggatgaagaagaggtggaacacagctactacaac agcctccccgggaaggagccgcccccaggagggctggtggactccaggctcgccctcaca cagccctgtgccctgggggtcctcggtgcccttggccagggagcctctcctgctcgaaga gatgcccggggcctgcagtgggatgtaggcccctcagcccagcccggggatggctatgtg caggcggacgcccggggcccccgagactacgaggaccatctgtatgtcaacacgcagggt ctggacggccctgagtccctgcagcccgaggacagtcccaagaaggatctgttcgacatg cgtaagtgggggcaggcnnnnnnnnnnnnnnnnnnnnnnnnnnnngctggctcggtggca gccccccttcccgtggaggatcagtggcccagccccccgacccgccgggcccccatcgcc cccacggaggagcagctgcgtcaggagccctggtaccatggccagatgagccgccgggcg gcggaaaaactgcttcgggcagacggggacttcctcgtgcgggacagcgtcaccaatcct gggcagtacgtcctcaccggcatgcacggggggcagcccaagcacctgctgctggtggac cctgagggcgtggtgcggacgaaggacgtgctctttgagagcatcagccacctgatcgac taccacctgcagaatgggcagcccattgtagccgctgagagtgagctgcacttgcgaggc gtcgtcaagcgggagccctga

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