Bison bison bison (American bison): 104994392 Help Entry 104994392         CDS       T08726                                  Symbol THBS1 Name (RefSeq) thrombospondin-1   KO K16857   thrombospondin 1 Organism bbis  Bison bison bison (American bison) Pathway bbis04015   Rap1 signaling pathway bbis04115   p53 signaling pathway bbis04145   Phagosome bbis04148   Efferocytosis bbis04151   PI3K-Akt signaling pathway bbis04350   TGF-beta signaling pathway bbis04510   Focal adhesion bbis04512   ECM-receptor interaction bbis04820   Cytoskeleton in muscle cells bbis05144   Malaria bbis05165   Human papillomavirus infection bbis05205   Proteoglycans in cancer bbis05206   MicroRNAs in cancer bbis05219   Bladder cancer Brite KEGG Orthology (KO) [BR:bbis00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     104994392 (THBS1)    04350 TGF-beta signaling pathway     104994392 (THBS1)    04151 PI3K-Akt signaling pathway     104994392 (THBS1)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     104994392 (THBS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     104994392 (THBS1)    04148 Efferocytosis     104994392 (THBS1)   09143 Cell growth and death    04115 p53 signaling pathway     104994392 (THBS1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     104994392 (THBS1)   09142 Cell motility    04820 Cytoskeleton in muscle cells     104994392 (THBS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     104994392 (THBS1)    05205 Proteoglycans in cancer     104994392 (THBS1)   09162 Cancer: specific types    05219 Bladder cancer     104994392 (THBS1)   09172 Infectious disease: viral    05165 Human papillomavirus infection     104994392 (THBS1)   09174 Infectious disease: parasitic    05144 Malaria     104994392 (THBS1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:bbis04131]     104994392 (THBS1)   09183 Protein families: signaling and cellular processes    00536 Glycosaminoglycan binding proteins [BR:bbis00536]     104994392 (THBS1) Membrane trafficking [BR:bbis04131]  Endocytosis   Phagocytosis    Opsonins     104994392 (THBS1) Glycosaminoglycan binding proteins [BR:bbis00536]  Heparan sulfate / Heparin   Extracellular matrix molecules    104994392 (THBS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TSP_C TSP_3 TSP_1 TSP1_spondin VWC TSP1_CFP_C EGF_3 cEGF TSP1_ADAMTS EGF_CA Laminin_G_3 Laminin_G_2 TSP1_CCN EGF Laminin_G_1 Motif Other DBs NCBI-GeneID:  104994392 NCBI-ProteinID:  XP_010846231 Ensembl:  ENSBBBG00000015017 UniProt:  A0A6P3HUI8 LinkDB All DBs Position Unknown AA seq 1170 aa AA seqDB search MGLAWGLGILLLLHACGSNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR IEDANLIPPVPDKKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLAVERKDHSGQVFSVV SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD VPIQSIFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVFV TLDNNVVNGSSPAIRTDYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK VTEENKELANELRRPPLCYHNGVQYRTGDEWTVDSCTECRCQNSVTICKKVSCPIMPCSN ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSVTCGNGIQQRGRSCDSLNNRCEGSSVQT RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGKARE TKACQKDSCPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQI CNKQDCPIDGCLSNPCFAGVQCTSYPDGSWKCGACPPGYSGDGVECKDVDECKEVPDACF NHNGEHRCENTDPGYNCLPCPPRFTGSQPFGRGVEHATANKQVCKPRNPCTDGTHDCNKN AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNEDLLCVANATYHCRKDNCPN LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN HNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQKDTDMDGVGDQCDNCPLEH NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN DGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDQDKVPDIDDICPENVDISETDFRRF QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL WHTGNTSGQVRTLWHDPRHIGWKDFTAYRWHLSHRPKTGFIRVVMYEGKKIMADSGPIYD KTYAGGRLGLFVFSQEMVFFSDLKYECRDS NT seq 3513 nt NT seq  +upstreamnt  +downstreamnt atggggctggcctggggactcggtatcctgctcctgttgcatgcctgcggctccaaccgc attccagagtctgggggagacaacagtgtgtttgacatctttgaactcaccggagctgcc cgcaagggctctgggcgccgactggtgaagggccctgacccttctagcccagctttccgc atcgaggatgccaacctgatcccccctgtgcctgacaagaagttccaagacctagtggat gctgtgcgggcggagaaaggtttcctcctcctggcctccctgaggcaaatgaagaagacc cggggtaccctgctggctgtggagcggaaagaccactctggccaggtcttcagcgtggtc tccaatggcaaggcgggcaccctggacctgagcctgaccgtgcaggggaagcagcatgtg gtgtcggtggaagaagcactcctggcgactggccagtggaagagcatcaccctgtttgtg caggaggacagggcccagctgtacatcgactgtgagaagatggagaatgcggagctggat gtccccatccagagcatcttcaccagggacctggccagcatcgccagactccgcattgcc aaaggaggtgtcaatgacaatttccagggggtgctgcagaatgtaaggtttgtctttgga accacaccagaagacatcctcaggaacaaaggctgctccagctctaccagtgtctttgtc acccttgacaacaacgtggtgaatgggtccagccctgccatccgcaccgactacattggc cacaagacaaaggacctgcaagccatctgtggcatctcatgtgacgagctgtccagcatg gtcctggagctcaggggtctacgcaccatcgtgaccacgctgcaggacagtatccgcaaa gtgaccgaagagaacaaagagctggccaacgagctgaggaggcccccactctgctaccac aacggagtgcagtacaggactggcgacgagtggacggtggacagctgcactgagtgtcgc tgccagaactcagttaccatctgcaaaaaagtgtcctgtcccatcatgccctgctccaat gccacagttccagatggagaatgctgcccacggtgctggcccagcgactctgcagacgac ggctggtccccgtggtctgagtggacctcttgctctgtgacctgtggcaatggaatccag cagcgtggccgctcctgcgacagcctcaacaacagatgcgagggctcctctgtgcagacg cggacctgccacatccaggagtgtgacaagagatttaaacaggatggcggctggagccac tggtccccatggtcatcttgctccgtaacatgtggagacggtgtgatcacaaggatccgg ctctgcaactcccccagcccccagatgaatgggaagccgtgtgagggcaaagcccgggag accaaagcctgccagaaagactcctgccccatcaatggaggctggggaccttggtcacca tgggacatctgttctgtcacctgtggaggaggggtacagaaacgtagccggctctgcaac aaccccacaccccagtttggaggcaaggactgcgttggtgatgtgacagaaaaccagatc tgcaacaagcaggactgtcccattgacggatgcctgtccaatccctgctttgctggtgtc cagtgtaccagctaccctgatggcagctggaagtgtggtgcctgtcccccaggctatagt ggagatggagtcgagtgcaaagacgttgatgagtgcaaagaagtccctgatgcctgcttc aaccacaatggagagcacaggtgtgagaacacagaccccggctacaactgcctgccctgc ccaccgcgcttcactggctcgcagccctttggccggggcgtggaacatgccaccgccaac aagcaggtatgcaagccccgaaacccctgcacagacgggacacacgactgcaacaagaac gccaagtgcaactacctgggccactacagcgaccccatgtaccgctgcgagtgcaagcct ggctacgccggcaacggcatcatctgcggggaggacacagacctggacggctggcccaat gaggacctgctgtgcgtggccaatgcaacttaccactgcagaaaggataattgccccaac cttcccaactcagggcaggaagactatgacaaggatggaatcggcgatgcctgcgatgat gacgatgacaatgataagattccagatgacagggacaactgtccattccattacaaccca gcccagtacgactatgacagagatgacgtgggagaccgctgtgacaactgcccctacaac cacaacccagaccaggctgacacagataacaatggggaaggagacgcctgcgcagctgac attgatggggacggtatcctcaatgaacgggacaactgccagtatgtctacaatgtggac cagaaagacactgacatggacggggttggtgatcagtgtgacaactgccccctggaacac aatccagaccagctcgactctgactcggaccgcattggagacacctgtgacaacaatcag gatattgatgaagacggccaccagaacaatctggacaactgtccctacgtgcccaacgcc aaccaggctgaccatgacaaggatggcaaaggcgatgcctgtgaccatgatgacgacaat gatggcattcctgatgaccgggacaactgcaggctggtgcccaatcctgaccagaaggac tctgatggtgatggtcgaggtgatgcttgcaaagatgattttgaccaggacaaggtgcca gacattgatgacatctgtcccgaaaatgttgatatcagtgagactgatttccgccgattc cagatgattcctctagatcccaaagggacatcccagaatgaccctaactgggttgtacgc catcagggtaaagaactcgtccagactgtcaactgtgaccctggacttgctgtaggttat gacgaatttaacgccgtggacttcagtggcaccttcttcatcaacaccgagagggacgac gactatgccggctttgtgtttggctaccagtccagcagccgcttctatgttgtgatgtgg aagcaagtcactcagtcctactgggacaccaaccccacgagggctcaggggtactctgga ctttccgtgaaggttgtaaactccaccacggggcctggcgagcacctgcggaatgccctg tggcacacaggaaacacctctggccaggtgcgcacactgtggcatgaccctcgtcacatt ggctggaaagatttcactgcctacagatggcatctgagccataggccaaagacaggtttc atcagagtggtaatgtatgaagggaagaaaatcatggctgactcaggacccatctatgac aaaacctatgctggtgggaggctaggcttgttcgtcttctctcaagaaatggtgttcttc tccgacctgaaatatgaatgcagagactcctaa

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