Bison bison bison (American bison): 104997905 Help Entry 104997905         CDS       T08726                                  Symbol PSEN2 Name (RefSeq) presenilin-2   KO K04522   presenilin 2 [EC:3.4.23.-] Organism bbis  Bison bison bison (American bison) Pathway bbis04330   Notch signaling pathway bbis04722   Neurotrophin signaling pathway bbis05010   Alzheimer disease bbis05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:bbis00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     104997905 (PSEN2)  09150 Organismal Systems   09156 Nervous system    04722 Neurotrophin signaling pathway     104997905 (PSEN2)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     104997905 (PSEN2)    05022 Pathways of neurodegeneration - multiple diseases     104997905 (PSEN2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:bbis01002]     104997905 (PSEN2) Peptidases and inhibitors [BR:bbis01002]  Aspartic peptidases   Family A22: presenilin family    104997905 (PSEN2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Presenilin Motif Other DBs NCBI-GeneID:  104997905 NCBI-ProteinID:  XP_010851177 Ensembl:  ENSBBBG00000012223 UniProt:  A0A6P3IGZ9 LinkDB All DBs Position Unknown AA seq 449 aa AA seqDB search MLTFMASDSEEEVCDERTSLMSAESPTPRSCQDGRQGLEDGESAAQWRSQESEEDHEEED PDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQL IYTPFSEDTPSVGQRLLNSVLNTLIMISVIVTMTIFLVVLYKYRCYKFIHGWLIMSSLML LFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALM ALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMV WTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPDVFEPPLPGYPGEELEEEEERG VKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPIS ITFGLIFYFSTDNLVRPFMDTLASHQLYI NT seq 1350 nt NT seq  +upstreamnt  +downstreamnt atgctcacattcatggcctctgacagcgaggaagaagtgtgtgatgagcggacgtccctg atgtcagccgagagccccacgccgcgctcctgccaggacggccggcagggcctggaggac ggagagagtgccgcccagtggagaagccaggagagtgaggaggaccacgaggaggaggac cctgaccgctatgtctgcagtggggttcctgggcggccgccaggcctggaggaggagctg accctcaaatacggggcaaagcacgtgatcatgttgtttgtgcctgtcacactgtgcatg atcgtggtggtggccaccatcaagtccgtgcgcttctacacagagaagaatggacagctc atctataccccgttctccgaggacacgccctcagtgggccagcggctcctcaactccgtg ctcaacaccctcatcatgatcagcgtcattgtcaccatgacgatcttcctggttgtgctc tacaagtaccgctgctacaagttcatccacggttggctgatcatgtcctctctgatgttg ctcttcctcttcacctacatctacctcggggaagtgctcaagacctacaatgtggccatg gactacccgaccctgttcctgaccgtctggaacttcggggcggtgggcatggtgtgcatc cactggaagggccccctagtgctgcagcaggcctacctcatcatgatcagcgcgctcatg gccttggtgttcatcaagtacctcccggagtggtccgcctgggtcattctgggcgccatc tccgtgtatgatcttgtggctgtgctgtgtcccaaagggccactgaggatgctcgtggaa accgcgcaggagagaaatgagcccatattccctgccctcatatactcatccgccatggtc tggaccgtgggcatggccaagctggacccttcctctcagggagcccttcagctcccctac gacccggagatggaagaagactcctatgacagttttggggagccctcgtaccctgacgtc tttgagcccccgctgcctggctacccgggggaggagctggaggaagaggaggaaaggggc gtgaagctcggcctcggagacttcatcttctacagtgtgctggtgggcaaggcggccgcc acgggcagcggggactggaacaccacactggcctgctttgtggccatcctcattggtttg tgtctgaccctcctgctgctcgccgtgttcaagaaggcgctgcccgccctccccatctcc atcacgttcgggctcatcttctacttctccacggacaacctggtgcggcctttcatggac accctggcctcccatcagctctacatctga

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